Evaluación de la calidad de un servicio de voluntariado en oncología: un Análisis Importancia-Valoración (IPA)

Objective: Using an Importance-Performance Analysis (IPA), this paper examined a Radiotherapy and Oncological Patient and Non-patient perceived importance and performance of ten Humanization Volunteer Program selection factors in the General Hospital in Spain.Methods: The authors identified a list of seven items from the Health-marketing literature reviews, and each item was rated using a 5-point Likert scale. Responses were obtained of 148 usable interviews.Results: The importance-performance patient grid was corrected with literature recommendations and, in the patient sample, shows three items fall in the “Keep up the good work” quadrant, four items fall into the “Low priority” quadrant, zero items fall into the “Possible overkill” quadrant, and no items fall in the “Concentrate here” quadrant. Non-patient (n=80) factors means shows statistical differences with patient (n=68) means in catering (t=-2.38; df.=146; p<0.05), and information (t=2.16; df146; p<0,05).Conclusions: The results are useful in identifying areas for strategic focus to help Health Services managers develop humanization programs with volunteer workers and different program users. Implication to volunteer programs managers and researchers were discussed.Objetivo: Usando el Análisis de Importancia-Valoración (IPA), este artículo examina la importancia y valoración percibidas por pacientes oncológicos y sus acompañantes de un programa de humanización realizado por voluntarios en un servicio de Radioterapia de un hospital general en España.Método: Los autores identifican una lista de siete ítems que surgen de la revisión de literatura en Marketing Sanitario; cada ítem fue puntuado con una escala Likert de 5 puntos.Resultados: Los resultados se obtuvieron de las respuestas a 148 entrevistas. El gráfico fue corregido con las recomendaciones sugeridas en la literatura y en el caso de los pacientes, muestra tres factores que caen en el cuadrante de “Mantener el buen trabajo”, cuatro atributos caen dentro del cuadrante de ”Baja Prioridad” y ningún atributo se observa en los cuadrantes de “Posible dilapidación de recursos” y “Concentrarse aquí”. Se encuentran diferencias entre medias de la muestra de pacientes (n=68) y de familiares acompañantes (n=80) en los atributos de catering (t=-2,38; g.l.=146; p<0,05), y en el de información (t=2,16; g.l.=146; p<0,05).Conclusiones: Los resultados parecen útiles para identificar áreas de interés para los gestores de los servicios de salud para desarrollar programas de humanización de servicios basados en el trabajo de voluntarios y dirigidos a diferentes tipos de usuarios. Las implicaciones para los gerentes de programas de voluntariado e investigadores son discutidas

Evaluación de la calidad de un servicio de voluntariado en oncología: un Análisis Importancia-Valoración (IPA)

Objective: Using an Importance-Performance Analysis (IPA), this paper examined a Radiotherapy and Oncological Patient and Non-patient perceived importance and performance of ten Humanization Volunteer Program selection factors in the General Hospital in Spain.Methods: The authors identified a list of seven items from the Health-marketing literature reviews, and each item was rated using a 5-point Likert scale. Responses were obtained of 148 usable interviews.Results: The importance-performance patient grid was corrected with literature recommendations and, in the patient sample, shows three items fall in the “Keep up the good work” quadrant, four items fall into the “Low priority” quadrant, zero items fall into the “Possible overkill” quadrant, and no items fall in the “Concentrate here” quadrant. Non-patient (n=80) factors means shows statistical differences with patient (n=68) means in catering (t=-2.38; df.=146; p&lt;0.05), and information (t=2.16; df146; p&lt;0,05).Conclusions: The results are useful in identifying areas for strategic focus to help Health Services managers develop humanization programs with volunteer workers and different program users. Implication to volunteer programs managers and researchers were discussed.</p

Histological assessment of nanostructured fibrin-agarose skin substitutes grafted in burnt patients. A time-course study

A previously developed fibrin-agarose skin model—UGRSKIN—showed promising clinical results in severely burnt patients. To determine the histological parameters associated to the biocompatibility and therapeutic effects of this model, we carried out a comprehensive structural and ultrastructural study of UGRSKIN grafted in severely burnt patients after 3 months of follow-up. The grafted epidermis was analogue to native human skin from day 30th onward, revealing well-structured strata with well-differentiated keratinocytes expressing CK5, CK8, CK10, claudin, plakoglobin, filaggrin, and involucrin in a similar way to controls, suggesting that the epidermis was able to mature and differentiate very early. Melanocytes and Langerhans cells were found from day 30th onward, together with a basement membrane, abundant hemidesmosomes and lack of rete ridges. At the dermal layer, we found an interface between the grafted skin and the host tissue at day 30th, which tended to disappear with time. The grafted superficial dermis showed a progressive increase in properly-oriented collagen fibers, elastic fibers and proteoglycans, including decorin, similarly to control dermis at day 60-90th of in vivo follow-up. Blood vessels determined by CD31 and SMA expression were more abundant in grafted skin than controls, whereas lymphatic vessels were more abundant at day 90th. These results contribute to shed light on the histological parameters associated to biocompatibility and therapeutic effect of the UGRSKIN model grafted in patients and demonstrate that the bioengineered skin grafted in patients is able to mature and differentiate very early at the epithelial level and after 60–90 days at the dermal level.Consejería de Salud y Familias, Junta de AndalucíaGrant/Award Numbers: PE- 0395-2019, PI-0458-2016Consejería de Transformación Económica, Industria,Conocimiento y Universidades, Grant/Award Number: B-CTS-450-UGR20Instituto de Salud Carlos III, Grant/Award Number: AC17/0001

Fibrin and Marine-Derived Agaroses for the Generation of Human Bioartificial Tissues: An Ex Vivo and In Vivo Study

Development of an ideal biomaterial for clinical use is one of the main objectives of current research in tissue engineering. Marine-origin polysaccharides, in particular agaroses, have been widely explored as scaffolds for tissue engineering. We previously developed a biomaterial based on a combination of agarose with fibrin, that was successfully translated to clinical practice. However, in search of novel biomaterials with improved physical and biological properties, we have now generated new fibrin-agarose (FA) biomaterials using 5 different types of agaroses at 4 different concentrations. First, we evaluated the cytotoxic effects and the biomechanical properties of these biomaterials. Then, each bioartificial tissue was grafted in vivo and histological, histochemical and immunohistochemical analyses were performed after 30 days. Ex vivo evaluation showed high biocompatibility and differences in their biomechanical properties. In vivo, FA tissues were biocompatible at the systemic and local levels, and histological analyses showed that biointegration was associated to a pro-regenerative process with M2-type CD206-positive macrophages. These results confirm the biocompatibility of FA biomaterials and support their clinical use for the generation of human tissues by tissue engineering, with the possibility of selecting specific agarose types and concentrations for applications requiring precise biomechanical properties and in vivo reabsorption times.Hispanagar SA, Burgos, Spain, through CDTI, Ministry of Science and Innovation, Spain, Programa Operativo Plurirregional de Crecimiento Inteligente (CRIN) IDI-20180052Spanish Plan Nacional de Investigacion Cientifica, Desarrollo e Innovacion Tecnologica (I + D + I) of the Spanish Ministry of Science and Innovation (Instituto de Salud Carlos III) FIS PI20/0317 FIS PI20/0318 FIS PI21/0980 ICI19/00024 ICI21/00010Junta de Andalucia PE-0395-2019 PI-0442-2019 PI-0086-2020Consejeria de Transformacion Economica, Industria, Conocimiento y Universidades B-CTS-504-UGR2

Characterization of the human ridged and non-ridged skin: a comprehensive histological, histochemical and immunohistochemical analysis

The structure of the human skin is directly dependent on its location and the mechanical forces to which it is subjected. In the present work, we have performed a comprehensive analysis of the human ridged and non-ridged skin to identify the differences and similarities between both skin types. For this purpose, human skin samples were obtained from dorsal hand skin (DHS), palmar hand skin (PHS), dorsal foot skin (DFS) and plantar foot skin (PFS) from the same cadaveric donors. Histological, histochemical and semiquantitative and quantitative immunohistochemical analyses were carried out to evaluate the epidermis, dermis and basement membrane. Results show that the epithelial layer of ridged skin had larger cell number and size than non-ridged skin for most strata. Melanocytes and Langerhans cells were more abundant in non-ridged skin, whereas Merkel cells were preferentially found in ridged skin. The expression pattern of CK5/6 was slightly differed between non-ridged and ridged skin. Involucrin expression was slightly more intense in non-ridged skin than in ridged skin. Collagen was more abundant in foot skin dermis than in hand skin, and in ridged skin as compared to non-ridged skin. Elastic fibers were more abundant in DHS. Biglycan was more abundant in foot skin than in hand skin. No differences were found for blood and lymphatic vessels. The basement membrane laminin was preferentially found in foot skin. These results revealed important differences at the epithelial, dermal and basement membrane levels that could contribute to a better knowledge of the human skin histology.This work was partially supported by Award no. AC17/00013 (NanoGSkin) by ISCIII thorough AES 2017 and within the EuroNanoMed framework

Effects of Four Formulations of Prostaglandin Analogs on Eye Surface Cells. A Comparative Study

We evaluated the cytotoxic effects of four prostaglandin analogs (PGAs) used to treat glaucoma. First we established primary cultures of conjunctival stromal cells from healthy donors. Then cell cultures were incubated with different concentrations (0, 0.1, 1, 5, 25, 50 and 100%) of commercial formulations of bimatoprost, tafluprost, travoprost and latanoprost for increasing periods (5 and 30 min, 1 h, 6 h and 24 h) and cell survival was assessed with three different methods: WST-1, MTT and calcein/AM-ethidium homodimer-1 assays. Our results showed that all PGAs were associated with a certain level of cell damage, which correlated significantly with the concentration of PGA used, and to a lesser extent with culture time. Tafluprost tended to be less toxic than bimatoprost, travoprost and latanoprost after all culture periods. The results for WST-1, MTT and calcein/AM-ethidium homodimer-1 correlated closely. When the average lethal dose 50 was calculated, we found that the most cytotoxic drug was latanoprost, whereas tafluprost was the most sparing of the ocular surface in vitro. These results indicate the need to design novel PGAs with high effectiveness but free from the cytotoxic effects that we found, or at least to obtain drugs that are functional at low dosages. The fact that the commercial formulation of tafluprost used in this work was preservative-free may support the current tendency to eliminate preservatives from eye drops for clinical use.This study was supported by the Spanish Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica (I+D+I) from the Spanish Ministry of Economy and Competitiveness (Instituto de Salud Carlos III), grants FIS PI11/1582 and FIS PI14/0955 (co-financed by FEDER funds, European Union) and by Grant P10-CTS-6060 from the Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucia, Spain (Proyectos de Excelencia)

Magisterio, educación y humanidades

172 p.Diversas circunstancias del presente obligan a pensar acerca del papel de la formación humanística en todos los procesos educativos. Las manifestaciones de intolerancia, barbarie, corrupción, falta de pertenencia, ausencia de memoria histórica o espiritualidad, entre otros factores, llevan a analizar, en profundidad y con esperanza, los diferentes conflictos humanos. Así mismo, a procurar alzar la voz para ofrecer algunas reflexiones que iluminen posibilidades de diálogo y reconocimiento, las cuales colaboren con la reconstrucción del tejido social que, por la diversidad de manifestaciones de una realidad en crisis, necesita algunas pistas para atender las necesidades más apremiantes del contexto colombiano, aunque estas sean de carácter teórico, como las que se presentan en el siguiente volumen. La participación activa de los docentes del departamento de Humanidades de la Universidad Católica de Colombia, permite reconocer que cada quien, desde su campo disciplinar y académico, es consciente de la necesidad de asumir la vocería para reflexionar y dialogar sobre diversidad de temas y autores, que pueden orientar las posibilidades de comprensión frente a las situaciones que se viven en el día a día y que no son ajenas a las aulas de clase y a la cotidianidad de la comunidad universitaria. Es por ello que en este libro se presentan reflexiones en torno a: el papel de la educación política; la alteridad; la relación entre filosofía y pintura; los aportes del Magisterio de la Iglesia al concepto de funcionamiento familiar; la consciencia política; Jesucristo como el rostro de la felicidad cristiana; el desarrollo de la Constitución Pastoral Gaudium et Spes en las encíclicas de S.S. Benedicto XVI y su relación con la Doctrina Social de la Iglesia; algunas lecciones sobre la mujer y el hombre en el Magisterio; la pedagogía de la pregunta y la respuesta en la posibilidad de un proyecto de vida; la educación en el Magisterio Pontificio; y las enseñanzas de la teología del cuerpo.Prólogo 1. Educar para pensar políticamente: el papel de la educación política en el contexto colombiano 2. El lenguaje: camino hacia la alteridad 3. Merleau-Ponty: filosofía y pintura. La duda de Cézanne 4. Aportes del Magisterio de la Iglesia al concepto de funcionamiento familiar (APGAR) 5. De la ceguera a la lucidez: camino hacia una consciencia política 6. Jesucristo: el rostro de la felicidad cristiana 7. Desarrollo de la constitución pastoral Gaudium et spes en las encíclicas de S.S. Benedicto XVI y su relación con la Doctrina Social de la Iglesia 8. Algunas lecciones sobre la mujer y el hombre en el Magisterio 9. Un proyecto de vida desde la pedagogía de la pregunta y la respuesta 10. La educación en el Magisterio Pontificio: algunas enseñanzas de la teología del cuerpo Bibliografí

Prediction of the shear strength of reinforced masonry walls using a large experimental database and artificial neural networks

This paper analyses the accuracy of a selection of expressions currently available to estimate the in-plane shear strength of reinforced masonry (RM) walls, including those presented in some international masonry codes. For this purpose, predictions of such expressions are compared with a set of xperimental results reported in the literature. The experimental database includes specimens built with ceramic bricks and concrete blocks tested in partially and fully grouted conditions, which typically present a shear failure mode. Based on the experimental data collected and using artificial neural networks (ANN), this paper presents alternative expressions to the different existing methods to predict the in-plane shear strength of RM walls. The wall aspect ratio, the axial pre-compression level on the wall, the compressive strength of masonry, as well as the amount and spacing of vertical and horizontal reinforcement throughout the wall are taken into consideration as the input parameters for the proposed expressions. The results obtained show that ANN-based proposals give good predictions and in general fit the experimental results better than other calculation methods.This work was supported by the Fondo Nacional de Ciencia y Tecnologia de Chile, (Fondecyt de Iniciacion) [grant number 11121161].Aguilar, V.; Sandoval, C.; Adam Martínez, JM.; Garzón-Roca, J.; Valdebenito, G. (2016). Prediction of the shear strength of reinforced masonry walls using a large experimental database and artificial neural networks. Structure and Infrastructure Engineering. 12(12):1661-1674. https://doi.org/10.1080/15732479.2016.1157824S16611674121

BiFiSo-CSIC: balance de una lucha multidisciplinar contra la pandemia

En marzo de 2020 se declaró el estado de emergencia en España a raíz de una pandemia causada por el virus llamado SARS-CoV-2. La enfermedad, denominada COVID-19, produce una gran letalidad en personas de edad avanzada. Estas excepcionales circunstancias dictaron medidas inéditas en nuestro país: confinamiento domiciliario, cierre de colegios y comercios no esenciales. El Consejo Superior de Investigaciones Científicas (CSIC) reaccionó de inmediato: recién iniciado el confinamiento todos los investigadores de esta institución fueron convocados para dedicar parte de su tiempo a investigar sobre la pandemia. La respuesta fue instantánea y personas de todas las áreas de investigación se brindaron a contribuir con su granito de arena. Lo que al principio iba a suponer una media del 20% del tiempo de cada investigador pasó a ocupar toda la jornada: y así hasta hoy. En este contexto surge el proyecto BiFiSo, en el cual desde la biología, la filosofía o la antropología hemos estudiado y explicado la pandemia, complementando mutuamente la visión de nuestras respectivas especialidades.Consejo Superior de Investigaciones Científicas aporta financiación como institución fundacional de The Conversation ES. Universidad de Málaga aporta financiación como institución colaboradora de The Conversation ES.Peer reviewe

Gestión cultural: retos y experiencias desde la academia

Gestión Cultural: retos y experiencias desde la academia es la compilación de dieciocho trabajos de titulación de estudiantes de la segunda y tercera cohorte de la Maestría en Gestión Cultural que oferta la Universidad Politécnica Salesiana en sus sedes de Cuenca, Quito y Guayaquil. Este programa de posgrado surgió como respuesta a la necesidad de cualificar a profesionales ya vinculados al sector y que provienen de otras disciplinas académicas; así como de nuevos actores y gestores que dinamicen la gestión cultural del país. Los trabajos aquí presentados (artículos y proyectos de titulación) son una muestra de la formación multidisciplinaria de profesionales a nivel nacional, preparados para desarrollar modelos de gestión cultural. Representan una muestra de la formación especializada en la gestión de los recursos e industrias culturales; dominio de los conceptos de cultura, patrimonio e identidad; habilidades en la ejecución de proyectos culturales; aplicación de tecnologías especializadas a los distintos campos del sector cultural; conocimiento de marco legislativo y políticas cultuales; manejo de la comunicación y mediación cultural