SONA project - Asthma management questionnaire

Questionnaire used to collect data in the SONA projec

Farmers’ Agro-climatological Knowledge of Changes in Precipitation and Temperature Extremes in Semi-arid Nakasongola

Understanding agro-climatological knowledge of farmers to climate extremes provides useful information in developing appropriate adaptation strategies critical for enhancing resilience of agricultural systems to climate change. This study was conducted to establish farmers’ agro-climatological knowledge and perceptions to trends of climate extremes in semi-arid Nakasongola district. Climate extremes were derived by analyzing rainfall and temperature data sets from 1970 to 2013 using RClimdex software. Data to establish farmer’s knowledge were collected through face to face household interviews and analyzed using descriptive statistics by SPSS. Annual total precipitation (PRCPTOT) index showed increasing non significant trends (P > 0.05). Heavy precipitation days (R10mm) showed weak positive non significant increasing trend (P < 0.05). Consecutive wet days (CWDs) were decreasing (P < 0.05) while consecutive dry days (CDDs) were significantly increasing. Percentage hot days were positively increasing while warm nights revealed a declining trend. Farmers’ perceived changes in rainfall and temperature extremes compared well with the observed climatological trends. CDDs and heavy precipitation days were the most perceived extremes. Key adaptation strategies included; fencing of grazeable land, use of drought tolerant pasture species, utilization of crop residues and pasture conservation, water harvesting and change of grazing time. Limited access to climate information and insecure land ownership rights were key barriers constraining adaptation. Therefore policies that ensure secure land ownership rights while improving farmers’ access to early warning information on climate events can effectively facilitate adaptation to climate change. Key words: Trends, precipitation, temperature, extremes and climate change DOI: 10.7176/JNSR/11-20-05 Publication date:October 31st 202

Effects of treating helminths during pregnancy and early childhood on risk of allergy-related outcomes: Follow-up of a randomized controlled trial.

BACKGROUND: Helminth infections, common in low-income countries, may protect against allergy-related disease. Early exposure may be a key. In the Entebbe Mother and Baby Study, treating helminths during pregnancy resulted in increased eczema rates in early childhood. We followed the cohort to determine whether this translated to increased asthma rates at school age. METHODS: This randomized, double-blind, placebo-controlled trial, conducted in Entebbe, Uganda, had three interventions. During pregnancy, women were randomized, simultaneously, to albendazole vs placebo and to praziquantel vs placebo. Their children were independently randomized to quarterly albendazole vs placebo from age 15 months to 5 years. We here report follow-up to age 9 years. Primary outcomes at 9 years were recent reported wheeze, skin prick test positivity (SPT) to common allergens and allergen-specific IgE positivity to dust mite or cockroach. Secondary outcomes were doctor-diagnosed asthma and eczema rates between 5 and 9 years, recent eczema, rhinitis and urticaria at 9 years, and SPT and IgE responses to individual allergens. RESULTS: 2507 pregnant women were enrolled; 1215 children were seen at age nine, of whom 1188 are included in this analysis. Reported wheeze was rare at 9 years (3.7%) while SPT positivity (25.0%) and IgE positivity (44.1%) were common. There was no evidence of a treatment effect for any of the three interventions on any of the primary outcomes. CONCLUSIONS: Prenatal and early-life treatment of helminths, in the absence of change in other exposures, is unlikely to increase the risk of atopic diseases later in childhood in this tropical, low-income setting

Effect of biotic and abiotic factors on composition and foraging intensity of subterranean termites

Elucidating the influence of ecological factors on composition and foraging intensity of subterranean termites is critical in development of sustainable termite management strategies. Our aim was therefore to analyze the effect of selected biotic and abiotic factors on composition and foraging intensity of termites. We used principal component and canonical correspondence analysis to select appropriate factors and to model relationships respectively. Macrotermes species occurred in sites where the quantity of litter was generally above the mean. However, Macrotermes herus (Rambur) and Macrotermes spp.4 occurred in sites where the litter quantity was below the mean. Trinervitermes oeconomous (Tragardh) and Odontoremes spp.1 were noted to occur in the direction of increasing quantity of biomass. Generally, most species occurred in sites where soil pH was above or slightly below the mean (4.8). Majority of the species were also noted to occur in sites where bulk density was below or slightly above the mean (1.55 g/cm3). Highest bait consumption (95%) occurred within a range of 55 to 60% basal cover beyond which the amount of bait consumed reduced. Litter and biomass quantity, pH and bulk density were noted as the most influential environmental variables determining composition of termites while basal cover was the major determinant of foraging intensity.Key words: Rangelands, Macrotermes, rangelands, vegetation, litter, biomass, basal-cover

Integrated termite management for improved rainwater management: A synthesis of selected African experiences

In eastern Africa, termites are perceived by farmers, livestock keepers, and many development agencies as serious agricultural pests that destroy pasture, crops and wooden infrastructure. Commonly use control measures have proven to be ineffective. When the CGIAR Challenge Program on Water and Food (CPWF) undertook research aimed at increasing agricultural water productivity in eastern Africa, termites destroyed early experiments designed to rehabilitate degraded land and increase water productivity. Building on indigenous knowledge from termite affected regions of Ethiopia, the CPWF and Uganda partners initiated research on integrated termite management. Results were promising. This literature review was commissioned to capture the state-of-knowledge about termite taxonomy, and diversity, farmers’ ethno-ecological knowledge of subterranean termites and termite management practices and control measures used in African crop and rangeland production systems. The paper offers some general lessons and guidelines for future agricultural research and development programs where termite damage is problematic. In brief, we conclude that ITM offers greater prospects for enabling termites to play important positive roles in agro-ecosystem functioning while reducing the damage they inflict on crop and livestock production

Life-course of atopy and allergy-related disease events in tropical sub-Saharan Africa: A birth cohort study.

BACKGROUND: In high-income countries, allergy-related diseases (ARDs) follow a typical sequence, the 'Atopic March'. Little is known about the life-course of ARDs in the markedly different, low-income, tropical environment. We describe ARDs in a tropical, African birth cohort. METHODS: Ugandan children were followed from birth to 9 years. ISAAC questionnaires were completed at intervals; doctor-diagnosed ARDs were recorded throughout follow-up. Skin prick tests (SPTs) were performed at 3 and 9 years. Atopy was defined as ≥1 positive SPT. RESULTS: Of the 2345 live-born children, 1214 (52%) were seen at 9 years. Wheeze and eczema were common in infancy, but by 9 years, only 4% reported recent wheeze, 5% eczema and 5% rhinitis. Between 3 and 9 years, atopy prevalence increased from 19% to 25%. Atopy at 3 or 9 years was associated with reported ARD events at 9 years, for example OR = 5.2 (95% CI 2.9-10.7) for atopy and recent wheeze at 9 years. Reported or doctor-diagnosed ARD events in early childhood were associated with the same events in later childhood, for example OR = 4.4 (2.3-8.4) for the association between reported wheeze before 3 years with reported recent wheeze at 9 years, but progression from early eczema to later rhinitis or asthma was not observed. CONCLUSION: Allergen sensitization started early in childhood and increased with age. Eczema and wheeze were common in infancy and declined with age. Atopy was strongly associated with ARD among the few affected children. The typical Atopic March did not occur. Environmental exposures during childhood may dissociate atopy and ARD

Productivity and morphology of Ankole cattle in three livestock production systems in Uganda

Phenotypic characterization is critical in breed improvement and conservation. To determine the performance and morphological features of Ankole cattle in three livestock production systems (LPS) of Uganda, 248 farms were studied. Height at withers (HW), heart girth (HG), body length (BL), ear length, horn length (HL), distance between horn tips (HS) and body weight (BW) were then measured on 120 bulls and 180 cows. Data were analysed using LPS (crop livestock, agropastoral, pastoral), county (Gomba, Kazo, Kiboga, Mawoggola, Nyabushozi) and sex (females, males) as main factors. In the results, age at sexual maturity was 23.6 ± 0.5 months for bulls and 22.7 ± 0.5 months for cows. Age at first calving was 33.2 ± 0.5 months, whereas calving interval was 12.9 ± 0.8 months. Lactation length differed between LPS (5.5 ± 0.4, 6.3 ± 0.3 and 7.4 ± 0.2 months in agropastoral, crop livestock and pastoral, respectively). Mean daily milk off take was 2.2 ± 0.1 kg/cow whereas preweaning calf survivability was 90.0 ± 6.5%. Sex and LPS significantly influenced HW, HL and HS. Positive correlations were observed between BW and HG, BL and HL. Correlation coefficients were much lower in females than in males, except for BW vs HG and BW vs HW. Results show wide variations both in performance and morphology suggesting that within breed selection scheme and/or management improvement may lead to productivity improvements

Clinical Presentation of T.b. rhodesiense Sleeping Sickness in Second Stage Patients from Tanzania and Uganda

Sleeping sickness, or Human African Trypanosomiasis (HAT), caused by Trypanosoma brucei rhodesiense is one of the most neglected tropical diseases. It affects mainly rural, poor East African populations and has very high socio-economic impacts. T.b. rhodesiense HAT is an acute disease; patients quickly progress from the first stage, where trypanosomes are detectable in blood and lymph, to the second stage, where parasites penetrate the central nervous system. If left untreated, T.b. rhodesiense HAT is fatal. Disease control is hampered by the absence of sensitive diagnostic tools and safe drugs. Second stage patients can only be treated with melarsoprol, a highly toxic, arsenical drug. It is more difficult to treat patients successfully at advanced stages of the disease, and late onset of treatment should be avoided. Yet, most patients are treated for other conditions prior to HAT diagnosis. Therefore, it is important that health personnel in T.b. rhodesiense endemic regions have a detailed understanding of the clinical presentation of the disease and consider regional characteristics of T.b. rhodesiense HAT for decision making and differential diagnosis

Uptake of HIV and syphilis testing of pregnant women and their male partners in a programme for prevention of mother-to-child HIV transmission in Uganda

OBJECTIVE: To describe uptake of HIV and syphilis testing in a prevention of mother-to-child HIV transmission programme in Uganda. METHODS: Analysis of data from routine HIV and syphilis testing at Entebbe Hospital antenatal services. RESULTS: A total of 20,738 women attended antenatal services. Exactly 62.8% of women, but only 1.8% of their male partners, accepted testing for HIV; 82.2% of women, but only 1.1% of their male partners accepted syphilis testing. Partners of women with positive HIV results were more likely to come for subsequent testing. Of 200 couples whose partners accepted HIV-testing within 30 days of one another, 19 (9.5%) were HIV-discordant, representing 65.5% of couples with at least one partner HIV-positive. HIV prevalence was 12.6% for women and 10.8% for men; syphilis prevalence was 4.0% for women and 6.2% for men. CONCLUSION: Uptake of HIV and syphilis testing was fairly good among pregnant women attending antenatal clinics at Entebbe Hospital, but very low among their male partners. The level of HIV-discordant couples was high. These clinics should be made more couples-friendly to identify both HIV-positive men for treatment and discordant couples for HIV prevention