Study of the photon strength functions and level density in the gamma decay of the n + 234U reaction

The accurate calculations of neutron-induced reaction cross sections are relevant for many nuclear applications. The photon strength functions and nuclear level densities are essential inputs for such calculations. These quantities for 235U are studied using the measurement of the gamma de-excitation cascades in radiative capture on 234U with the Total Absorption Calorimeter at n_TOF at CERN. This segmented 4π gamma calorimeter is designed to detect gamma rays emitted from the nucleus with high efficiency. This experiment provides information on gamma multiplicity and gamma spectra that can be compared with numerical simulations. The code diceboxc is used to simulate the gamma cascades while geant4 is used for the simulation of the interaction of these gammas with the TAC materials. Available models and their parameters are being tested using the present data. Some preliminary results of this ongoing study are presented and discussed

Application of the liposuction techniques and principles in specific body areas and pathologies

The buttocks have been a symbol of attraction, sexuality and eroticism since ancient times and therefore, they have an important role in defining the posterior body contour. More and more people are talking about and understand the meaning and the role that buttocks play in modeling and physical beauty. The three dimensional gluteoplasty (3-DGP) is an innovative technique that allows us to change volume, shape and firmness, not only in the buttocks but also in the adjacent regions such as the thighs and trochanters, becoming an ideal tool to answer the frequent reasons of consultation of our patients about this particular area of the body: ..

Myositis Ossificans of the temporalis muscle : case report

Los autores presentan un caso poco frecuente de miositis osificante del músculo temporal en un paciente varón de 51 años que se manifiesta con limitación de la apertura oral, con masa firme y dura en la fosa temporal derecha. La tomografia axial computerizada (TC) reveló una masa de densidad ósea localizada en la región temporal derecha, que unía el hueso temporal derecho con la apófisis coronoides y una imagen de pseudo-articulación en su porción media. La miositis osificante traumática es un tumor benigno que se localiza frecuentemente en las extremidades de los adolescentes. Los casos en el esqueleto craneofacial son raros. En esta localización, los músculos masetero y esternocleidomastoideo son los más frecuentemente afectados. Las características clínico patológicas de la miositis osificante pueden imitar otros tumores de los tejidos blandos, por lo que se requiere un cuidadoso diagnóstico diferencial. Histológicamente, la actividad osteoblástica asemeja a veces a un osteosarcoma, que requiere establecer el diagnóstico diferencial entre ambas entidades. En nuestro caso, el tratamiento quirúrgico, mediante abordaje combinado retromolar y hemicoronal, fue el elegido

"INTERGROWTH21st vs customized fetal growth curves in the assessment of the neonatal nutritional status: a retrospective cohort study of gestational diabetes"

Background Gestational diabetes mellitus is associated with increased incidence of adverse perinatal outcomes including newborns large for gestational age, macrosomia, preeclampsia, polyhydramnios, stillbirth, and neonatal morbidity. Thus, fetal growth should be monitored by ultrasound to assess for fetal overnutrition, and thereby, its clinical consequence, macrosomia. However, it is not clear which reference curve to use to define the limits of normality. Our aim is to determine which method, INTERGROWTH21st or customized curves, better identifies the nutritional status of newborns of diabetic mothers. Methods This retrospective cohort study compared the risk of malnutrition in SGA newborns and the risk of overnutrition in LGA newborns using INTERGROWTH21st and customized birth weight references in gestational diabetes. The nutritional status of newborns was assessed using the ponderal index. Additionally, to determine the ability of both methods in the identification of neonatal malnutrition and overnutrition, we calculate sensitivity, specificity, positive predictive value, negative predictive value and likelihood ratios. Results Two hundred thirty-one pregnant women with GDM were included in the study. The rate of SGA indentified by INTERGROWTH21st was 4.7% vs 10.7% identified by the customized curves. The rate of LGA identified by INTERGROWTH21st was 25.6% vs 13.2% identified by the customized method. Newborns identified as SGA by the customized method showed a higher risk of malnutrition than those identified as SGA by INTERGROWTH21st. (RR 4.24 vs 2.5). LGA newborns according to the customized method also showed a higher risk of overnutrition than those classified as LGA according to INTERGROWTH21st. (RR 5.26 vs 3.57). In addition, the positive predictive value of the customized method was superior to that of INTERGROWTH21st in the identification of malnutrition (32% vs 27.27%), severe malnutrition (22.73% vs 20%), overnutrition (51.61% vs 32.20%) and severe overnutrition (28.57% vs 14.89%). Conclusions In pregnant women with DMG, the ability of customized fetal growth curves to identify newborns with alterations in nutritional status appears to exceed that of INTERGROWTH21s

Trends in Hospitalization of Patients with Potentially Serious Diseases Evaluated at a Quick Diagnosis Clinic

Although quick diagnosis units (QDU) have become a cost-effective alternative to inpatient admission for diagnosis of potentially serious diseases, the rate of return hospitalizations among evaluated patients is unknown. This study examined the temporal trends in admissions of QDU patients through 15 years. Adult patients referred to QDU from 2004 to 2019 who were hospitalized between the first and last visit in the unit were eligible. Decisions about admissions were mainly based on the Appropriateness Evaluation Protocol and required independent validation by experienced clinicians using a customized tool. The final analysis included 825 patients. Patient characteristics and major reasons for admission were compared each year and linear trends were analyzed. Admission rates decreased from 7.2% in 2004-2005 to 4.3% in 2018-2019 (p < 0.0001). While a significant increasing trend was observed in the rate of admissions due to cancer-related complications (from 39.5% in 2004-2005 to 61.7% in 2018-2019; p < 0.0001), those due to anemia-related complications and scheduled invasive procedures experienced a significant downward trend. A likely explanation for these declining trends was the relocation of the unit to a new daycare center in 2013-2014 with recovery rooms and armchairs for IV treatments. The facts of this study could help in the provision of anticipatory guidance for the optimal management of patients at risk of clinical complications

What is the relevance of an ambulatory quick diagnosis unit or inpatient admission for the diagnosis of pancreatic cancer? A retrospective study of 1004 patients

Quick diagnosis units (QDU) have become an alternative hospital-based ambulatory medicine strategy to inpatient hospitalization for potentially serious illnesses in Spain. Whether diagnosis of pancreatic cancer is better accomplished by an ambulatory or inpatient approach is unknown. The main objective of this retrospective study was to examine and compare the diagnostic effectiveness of a QDU or inpatient setting in patients with pancreatic cancer. Patients with a diagnosis of pancreatic adenocarcinoma who had been referred to a university, tertiary hospital-based QDU or hospitalized between 2005 and 2018 were eligible. Presenting symptoms and signs, risk and prognostic factors, and time to diagnosis were compared. The costs incurred during the diagnostic assessment were analyzed with a microcosting method. A total of 1004 patients (508 QDU patients and 496 inpatients) were eligible. Admitted patients were more likely than QDU patients to have weight loss, asthenia, anorexia, abdominal pain, jaundice, and palpable hepatomegaly. Time to diagnosis of inpatients was similar to that of QDU patients (4.1 [0.8 vs 4.3 [0.6] days; P = .163). Inpatients were more likely than QDU patients to have a tumor on the head of the pancreas, a tumor size >2 cm, a more advanced nodal stage, and a poorer histological differentiation. No differences were observed in the proportion of metastatic and locally advanced disease and surgical resections. Microcosting revealed a cost of 347.76 (48.69) per QDU patient and 634.36 (80.56) per inpatient (P < .001). Diagnosis of pancreatic cancer is similarly achieved by an inpatient or QDU clinical approach, but the latter seems to be cost-effective. Because the high costs of hospitalization, an ambulatory diagnostic assessment may be preferable in these patients

Diseño y documentación del sistema de gestión de calidad para Seguridad Santander LTDA.

La elaboración del proyecto en la empresa SEGURIDAD SANTANDER LTDA., se llevó a cabo porque la misma solicitó el servicio para aspirar a la certificación de sus procesos y de esta forma adquirir ventajas competitivas en el mercado de seguridad privada; para esto se diseñaron los diferentes documentos exigidos por la norma mencionada para el Sistema de Gestión de Calidad, cuyo objetivo principal se basa en el mejoramiento continuo de sus actividades enfocadas en las necesidades y expectativas del cliente.The elaboration of the project in the company SEGURIDAD SANTANDER LTDA., was carried out because the same one asked for the service to aspire to the certification of its processes and this form to acquire competitive advantages in the market of private security; for this the different documents demanded by the norm mentioned for the System were designed from Management of Quality, whose primary objective is based on the continuous improvement of its focused activities in the necessities and expectations of the client

An event-driven link-level simulator for validation of AFDX and Ethernet avionics networks.

Aircraft are composed of many electronic systems: sensors, displays, navigation equipment and communication elements. These elements require a reliable interconnection, which is a major challenge for communication networks as high reliability and predictability requirements must be verified for safe operation. In addition, their verification via hardware deployments is limited because these are costly and make difficult to try different architectures and configurations, thus delaying the design and development in this area. Therefore, verification at early stages of the design process is of great importance that has to be supported via simulation. In this context, the present work presents an event-driven link level framework and simulator for the validation of avionics networks. The presented tool supports avionics protocols such as Avionics Full-Duplex Switched Ethernet (AFDX), which is a common protocol in avionics, as well as Ethernet, which is used with static routing in such scenarios. The simulator also uses realistic element models to provide accurate results. The proposed platform is evaluated in Clean Sky's Disruptive Cockpit for Large Passenger Aircraft architecture scenario. The speed of the verification is a key factor, so the computational cost is analyzed, proving that the execution time is linearly dependent on the number of messages sent.This work has been partially funded by: the Junta de Andalucía and the ERDF(European Regional Development Fund) Operational Programme in the framework of the CAPTOR project: “advanCed Avionics communications validation and verification PlaTfORm” (Ref. PYC20 RE 077 UMA); AERTEC Solutions (reference 8.06/5.59.5543, 8.06/5.59.5715 and 806/59. 5974) in the framework of project 2020 AS-DISCO: “Audio Suite for Disruptive Cockpit Demonstrator” (this project has received funding from the Clean Sky 2 Joint Undertaking under the European Union's Horizon 2020 research and innovation programme under Grant Agreement n°: 865416’); Ministry of Economic Affairs and Digital Transformation and the European Union - NextGenerationEU, in the framework of the Recovery, Transformation and Resilience Plan and the Recovery and Resilience Mechanism under the MAORI project; the Ministry of Science and Innovation (grant FPU21/04472); and the "Universidad de Málaga, Campus de Excelencia Internacional Andalucía Tech" through the “II Plan Propio de Investigación, Transferencia y Divulgación Científica”. The authors are grateful to Aertec Solutions for their support and collaboration in this project

Unintentional weight loss: Clinical characteristics and outcomes in a prospective cohort of 2677 patients.

Background Whereas there are numerous studies on unintentional weight loss (UWL), these have been limited by small sample sizes, short or variable follow‐up, and focus on older patients. Although some case series have revealed that malignancies escaping early detection and uncovered subsequently are exceptional, reported follow-ups have been too short or unspecified and necropsies seldom made. Our objective was to examine the etiologies, characteristics, and long-term outcome of UWL in a large cohort of outpatients. Methods We prospectively enrolled patients referred to an outpatient diagnosis unit for evaluation of UWL as a dominant or isolated feature of disease. Eligible patients underwent a standard baseline evaluation with laboratory tests and chest X-ray. Patients without identifiable causes 6 months after presentation underwent a systematic follow-up lasting for 60 further months. Subjects aged ≥65 years without initially recognizable causes underwent an oral cavity examination, a videofluoroscopy or swallowing study, and a depression and cognitive assessment. Results Overall, 2677 patients (mean age, 64.4 [14.7] years; 51% males) were included. Predominant etiologies were digestive organic disorders (nonmalignant in 17% and malignant in 16%). Psychosocial disorders explained 16% of cases. Oral disorders were second to nonhematologic malignancies as cause of UWL in patients aged ≥65 years. Although 375 (14%) patients were initially diagnosed with unexplained UWL, malignancies were detected in only 19 (5%) within the first 28 months after referral. Diagnosis was established at autopsy in 14 cases. Conclusion This investigation provides new information on the relevance of follow-up in the long-term clinical outcome of patients with unexplained UWL and on the role of age on this entity. Although unexplained UWL seldom constitutes a short-term medical alert, malignancies may be undetectable until death. Therefore, these patients should be followed up regularly (eg yearly visits) for longer than reported periods, and autopsies pursued when facing unsolved deaths

Caracterizacion Microestructural de un acero aisisae 1045 tratado termicamente en el intervalo intercritico

Los aceros doble fase cobran más importancia cada día debido a la buena combinación de propiedades mecánicas que ofrecen, siendo la industria automotriz su principal aplicación, la combinación de ferrita y martensita en su microestructura son las causantes de producir transformaciones en sus propiedades mecánicas. Para este estudio se empleó un acero AISI/SAE 1045 tratado desde temperaturas intercríticas donde se encuentran ferrita y austenita y al realizar el enfriamiento rápido se transforma en martensita. Las fracciones de cada fase, varían al aumentar la temperatura desde la cual se realiza el tratamiento. Para obtener estas proporciones se utilizó la norma ASTM 562, se realizaron diversos análisis microestructurales y pruebas de dureza. Al hacer el temple en agua y el posterior revenido desde diferentes temperaturas en el intervalo intercrítico, se encontró que en ciertos rangos había un cambio sustancial en las propiedades analizadas, luego del temple se realizó un revenido a 550C con tiempos de 1, 2 y 4 horas, las metalografías muestran una variación significativa de la fracción volumétrica de martensita, mientras que al templar en aceite el material presentó la típica estructura de un acero doble fase, en donde inclusive en algunos casos se evidenció la aparición de perlita.Dual phase steels become more important every day due to the good combination of mechanical properties that offer the automotive industry being the main application, the combination of ferrite and martensite microstructure are responsible for producing changes in their mechanical properties. For this study, an AISI/SAE 1045 steel treated from intercritical temperatures which are ferrite and austenite and rapid cooling to make the martensite becomes used. The fractions of each phase vary with increasing temperature from which the treatment is performed. For these ratios the ASTM 562 standard was used, various microstructural analysis and hardness tests were performed. Upon water quenching and subsequent tempering from different temperatures in the intercritical range, it was found that in certain ranges had a substantial change in the analyzed properties after quenching tempering was performed 550 ºC with times of 1, 2 and 4 hours, the metallographic show significant variation in the volume fraction of martensite, while the oil tempering the material showed the typical structure of a dual phase steel, where even in some cases the appearance of pearlite was evident