1,323 research outputs found

    Enhancement of the superconducting transition temperature from the competition between electron-electron correlations and electron-phonon interactions

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    We uncover that the competition between electron-electron correlations and electron-phonon interactions gives rise to unexpectedly huge enhancement of the superconducting transition temperature, several hundreds percent larger (≄\geq 200 K) than that of the case when only one of the two is taken into account (∌\sim 30 K). Our renormalization group analysis claims that this mechanism for the enhancement of the critical temperature is not limited on superconductivity but applied to various Fermi surface instabilities, proposing an underlying universal structure, which turns out to be essentially identical to that of a recent study [Phys. Rev. Lett. {\bf 108}, 046601 (2012)] on the enhancement of the Kondo temperature in the presence of Rashba spin-orbit interactions. We also discuss the stability of superconductivity against nonmagnetic randomness

    B --> pi and B --> K transitions in partially quenched chiral perturbation theory

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    We study the properties of the B-->pi and B-->K transition form factors in partially quenched QCD by using the approach of partially quenched chiral perturbation theory combined with the static heavy quark limit. We show that the form factors change almost linearly when varying the value of the sea quark mass, whereas the dependence on the valence quark mass contains both the standard and chirally divergent (quenched) logarithms. A simple strategy for the chiral extrapolations in the lattice studies with Nsea=2 is suggested. It consists of the linear extrapolations from the realistically accessible quark masses, first in the sea and then in the valence quark mass. From the present approach, we estimate the uncertainty induced by such extrapolations to be within 5%.Comment: Published versio

    PIONIER: a visitor instrument for the VLTI

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    PIONIER is a 4-telescope visitor instrument for the VLTI, planned to see its first fringes in 2010. It combines four ATs or four UTs using a pairwise ABCD integrated optics combiner that can also be used in scanning mode. It provides low spectral resolution in H and K band. PIONIER is designed for imaging with a specific emphasis on fast fringe recording to allow closure-phases and visibilities to be precisely measured. In this work we provide the detailed description of the instrument and present its updated status.Comment: Proceedings of SPIE conference Optical and Infrared Interferometry II (Conference 7734) San Diego 201

    The diameter of the CoRoT target HD 49933. Combining the 3D limb darkening, asteroseismology, and interferometry

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    Context. The interpretation of stellar pulsations in terms of internal structure depends on the knowledge of the fundamental stellar parameters. Long-base interferometers permit us to determine very accurate stellar radii, which are independent constraints for stellar models that help us to locate the star in the HR diagram. Aims: Using a direct interferometric determination of the angular diameter and advanced three-dimensional (3D) modeling, we derive the radius of the CoRoT target HD 49933 and reduce the global stellar parameter space compatible with seismic data. Methods: The VEGA/CHARA spectro-interferometer is used to measure the angular diameter of the star. A 3D radiative hydrodynamical simulation of the surface is performed to compute the limb darkening and derive a reliable diameter from visibility curves. The other fundamental stellar parameters (mass, age, and Teff) are found by fitting the large and small p-mode frequency separations using a stellar evolution model that includes microscopic diffusion. Results: We obtain a limb-darkened angular diameter of {\theta}LD = 0.445 \pm 0.012 mas. With the Hipparcos parallax, we obtain a radius of R = 1.42 \pm 0.04 Rsun. The corresponding stellar evolution model that fits both large and small frequency separations has a mass of 1.20 \pm 0.08 Msun and an age of 2.7 Gy. The atmospheric parameters are Teff = 6640 \pm 100 K, log g = 4.21 \pm 0.14, and [Fe/H] = -0.38.Comment: 4 pages, 4 figure

    Identification of distinct subgroups of Sj\uf6gren\u27s disease by cluster analysis based on clinical and biological manifestations: data from the cross-sectional Paris-Saclay and the prospective ASSESS cohorts

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    \ua9 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: Sj\uf6gren\u27s disease is a heterogenous autoimmune disease with a wide range of symptoms—including dryness, fatigue, and pain—in addition to systemic manifestations and an increased risk of lymphoma. We aimed to identify distinct subgroups of the disease, using cluster analysis based on subjective symptoms and clinical and biological manifestations, and to compare the prognoses of patients in these subgroups. Methods: This study included patients with Sj\uf6gren\u27s disease from two independent cohorts in France: the cross-sectional Paris-Saclay cohort and the prospective Assessment of Systemic Signs and Evolution of Sj\uf6gren\u27s Syndrome (ASSESS) cohort. We first used an unsupervised multiple correspondence analysis to identify clusters within the Paris-Saclay cohort using 26 variables comprising patient-reported symptoms and clinical and biological manifestations. Next, we validated these clusters using patients from the ASSESS cohort. Changes in disease activity (measured by the European Alliance of Associations for Rheumatology [EULAR] Sj\uf6gren\u27s Syndrome Disease Activity Index [ESSDAI]), patient-acceptable symptom state (measured by the EULAR Sj\uf6gren\u27s Syndrome Patient Reported Index [ESSPRI]), and lymphoma incidence during follow-up were compared between clusters. Finally, we compared our clusters with the symptom-based subgroups previously described by Tarn and colleagues. Findings: 534 patients from the Paris-Saclay cohort (502 [94%] women, 32 [6%] men, median age 54 years [IQR 43–64]), recruited between 1999 and 2022, and 395 patients from the ASSESS cohort (370 [94%] women, 25 [6%] men, median age 53 years [43–63]), recruited between 2006 and 2009, were included in this study. In both cohorts, hierarchical cluster analysis revealed three distinct subgroups of patients: those with B-cell active disease and low symptom burden (BALS), those with high systemic disease activity (HSA), and those with low systemic disease activity and high symptom burden (LSAHS). During follow-up in the ASSESS cohort, disease activity and symptom states worsened for patients in the BALS cluster (67 [36%] of 186 patients with ESSPRI score <5 at month 60 vs 92 [49%] of 186 at inclusion; p<0\ub70001). Lymphomas occurred in patients in the BALS cluster (five [3%] of 186 patients; diagnosed a median of 70 months [IQR 42–104] after inclusion) and the HSA cluster (six [4%] of 158 patients; diagnosed 23 months [13–83] after inclusion). All patients from the Paris-Saclay cohort with a history of lymphoma were in the BALS and HSA clusters. This unsupervised clustering classification based on symptoms and clinical and biological manifestations did not correlate with a previous classification based on symptoms only. Interpretation: On the basis of symptoms and clinical and biological manifestations, we identified three distinct subgroups of patients with Sj\uf6gren\u27s disease with different prognoses. Our results suggest that these subgroups represent different heterogeneous pathophysiological disease mechanisms, stages of disease, or both. These findings could be of interest when stratifying patients in future therapeutic trials. Funding: Fondation pour la Recherche M\ue9dicale, French Ministry of Health, French Society of Rheumatology, Innovative Medicines Initiative 2 Joint Undertaking, Medical Research Council UK, and Foundation for Research in Rheumatology

    PIBF+ extracellular vesicles from mouse embryos affect IL-10 production by CD8+ cells

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    Earlier evidence suggests, that the embryo signals to the maternal immune system. Extracellular vesicles (EVs) are produced by all types of cells, and because they transport different kinds of molecules from one cell to the other, they can be considered as means of intercellular communication. The aim of this work was to test, whether the embryo is able to produce sufficient amounts of EVs to alter the function of peripheral lymphocytes. Embryo-derived EVs were identified by their Annexin V biding capacity, and sensitivity to Triton X dependent lysis, using flow cytometry. Transmission electron microscopy was used to detect EVs at the implantation site. Progesterone-induced blocking factor (PIBF) expression in embryo-derived EVs was demonstrated with immuno-electron microscopy. The % of IL-10 + murine lymphocytes was determined by flow cytometry. EVs were present in embryo culture media, but not in empty media. Mouse embryo-derived EVs adhere to the surface of both CD4+ and CD8+ murine peripheral T lymphocytes, partly, via phosphatidylserine binding. The number of IL-10+ murine peripheral CD8+ cells increases in the presence of embryo-derived EVS, and this effect is counteracted by pre-treatment of EVs with an anti-PIBF antibody, suggesting that the embryo communicates with the maternal immune system via EVs

    Superconductivity in Fullerides

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    Experimental studies of superconductivity properties of fullerides are briefly reviewed. Theoretical calculations of the electron-phonon coupling, in particular for the intramolecular phonons, are discussed extensively. The calculations are compared with coupling constants deduced from a number of different experimental techniques. It is discussed why the A_3 C_60 are not Mott-Hubbard insulators, in spite of the large Coulomb interaction. Estimates of the Coulomb pseudopotential Ό∗\mu^*, describing the effect of the Coulomb repulsion on the superconductivity, as well as possible electronic mechanisms for the superconductivity are reviewed. The calculation of various properties within the Migdal-Eliashberg theory and attempts to go beyond this theory are described.Comment: 33 pages, latex2e, revtex using rmp style, 15 figures, submitted to Review of Modern Physics, more information at http://radix2.mpi-stuttgart.mpg.de/fullerene/fullerene.htm

    A ten thousand frames per second readout MAPS for the EUDET beam telescope

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    Designed and manufactured in a commercial CMOS 0.35 ÎŒm OPTO process for equipping the EUDET beam telescope, MIMOSA26 is the first reticule size pixel sensor with digital output and integrated zero suppression. It features a matrix of pixels with 576 rows and 1152 columns, covering an active area of ~224 mm2. A single point resolution of about 4 ÎŒm was obtained with a pixel pitch of 18.4 ÎŒm. Its architecture allows a fast readout frequency of ~10 k frames/s. The paper describes the chip design, test and major characterisation outcome

    Obscured Activity: AGN, Quasars, Starbursts and ULIGs observed by the Infrared Space Observatory

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    Some of the most active galaxies in the Universe are obscured by large quantities of dust and emit a substantial fraction of their bolometric luminosity in the infrared. Observations of these infrared luminous galaxies with the Infrared Space Observatory (ISO) have provided a relatively unabsorbed view to the sources fuelling this active emission. The improved sensitivity, spatial resolution and spectroscopic capability of ISO over its predecessor Infrared Astronomical Satellite (IRAS), has enabled significant advances in the understanding of the infrared properties of active galaxies. ISO surveyed a wide range of active galaxies which, in the context of this review, includes those powered by intense bursts of star-formation as well as those containing a dominant active galactic nucleus (AGN). Mid infrared imaging resolved for the first time the dust enshrouded nuclei in many nearby galaxies, while a new era in infrared spectroscopy was opened by probing a wealth of atomic, ionic and molecular lines as well as broad band features in the mid and far infrared. This was particularly useful since it resulted in the understanding of the power production, excitation and fuelling mechanisms in the nuclei of active galaxies including the intriguing but so far elusive ultraluminous infrared galaxies. Detailed studies of various classes of AGN and quasars greatly improved our understanding of the unification scenario. Far-infrared imaging and photometry also revealed the presence of a new very cold dust component in galaxies and furthered our knowledge of the far-infrared properties of faint starbursts, ULIGs and quasars. We summarise almost nine years of key results based upon ISO data spanning the full range of luminosity and type of active galaxies.Comment: Accepted for publication in 'ISO science legacy - a compact review of ISO major achievements', Space Science Reviews - dedicated ISO issue. To be published by Springer in 2005. 62 pages (low resolution figures version). Higher resolution PDFs available from http://users.physics.uoc.gr/~vassilis/papers/VermaA.pdf or http://www.iso.vilspa.esa.es/science/SSR/Verma.pd
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