Descrevendo a Magia: a construção narrativa de audiodescrições a partir de Harry Potter e a Pedra Filosofal

Trabalho de Conclusão de Curso apresentado ao Instituto Latino-Americano de Arte, Cultura e História da Universidade Federal da Integração Latino-Americana, como requisito parcial à obtenção do título de Bacharel em Cinema e Audiovisual. Orientador: Prof. Ms. Kira Santos PereiraA audiodescrição é um recurso de tecnologia assistiva que, através da tradução de informações visuais para verbais permite o acesso de pessoas com deficiência mental e visual à conteúdos audiovisuais. Contudo, a partir de uma mesma obra é possível que diferentes versões audiodescritas sejam criadas, devido às diversas possibilidades de construção narrativa para serem exploradas. Cada uma destas construções oferece não só uma mudança no modo como a história é contada, mas diferentes sensações para o espectador enquanto assiste a obra. A partir de uma analise comparativa entre a versão audiodescrita britânica e a versão americana de Harry Potter e a Pedra Filosofal (Chris Columbus, 2001) e de ideias desenvolvidas por teóricos das áreas de cinema, som e tradução, este trabalho busca encontrar diferenças nas construções narrativas de cada versão e pontuar o que elas representam para o espectador durante o processo de apreciação de obras audiovisuais que contam com este recursoAudio description is an assistive technology that gives people with visual or mental disabilities access to audiovisual content through a translation of visual elements into verbal codes. However, it is possible to achieve different audio described versions from just one content due to the existence of many narrative construction possibilities. Each of those offer not only a different way in which the story is told, but different feelings to be passed onto the audience. Through a compared analysis of both the british and american audio described version of Harry Potter and the Philosopher’s Stone (Chris Columbus, 2001) and the work of authors connected to fields of cinema, sound and translation, this assignment searches for differences in the narrative construction within every version and what they represent to the audience while watching i

Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro

The growth rate of numerous cancer cell lines is regulated in part by actions of neuropeptides of the vasoactive intestinal peptide (VIP) family, which also includes pituitary adenylate cyclase-activating peptide (PACAP), glucagon, and peptide histidine/isoleucine (PHI). The aim of this work was to investigate the effect of these peptides on the growth of the rat glioblastoma cell line C6 in vitro. We also sought to determine which binding sites were correlated with the effects observed. Proliferation studies performed by means of a CyQuant trade mark assay showed that VIP and PACAP strongly stimulated C6 cell proliferation at most of the concentrations tested, whereas PHI increased cell proliferation only when associated with VIP. Two growth hormone-releasing factor (GRF) derivatives and the VIP antagonist hybrid peptide neurotensin-VIP were able to inhibit VIP-induced cell growth stimulation, even at very low concentrations. Binding experiments carried out on intact cultured C6 cells, using 125I-labeled VIP and PACAP as tracers, revealed that the effects of the peptides on cell growth were correlated with the expression on C6 cells of polyvalent high-affinity VIP-PACAP binding sites and of a second subtype corresponding to very high-affinity VIP-selective binding species. The latter subtype, which interacted poorly with PACAP with a 10,000-fold lower affinity than VIP, might mediate the antagonist effects of neurotensin- VIP and of both GRF derivatives on VIP-induced cell growth stimulation

THE CHORÁ OF PATMOS (GREECE): ANALYSIS OF ARCHITECTURAL HERITAGE, IDENTIFICATION OF RISKS AND ASSESSMENT OF IMPACTS

Abstract. The Historic Center (Chorá) of Patmos, located in one of the Dodecanese Islands of Greece, was inscribed in the World Heritage List in 1999. The morphological feature, the housing typologies and the building techniques that characterize the Chorá provide an authentic and astonishing expression of the stylistic and typological models of the vernacular architecture of the Greek islands. This paper presents part of the research carried out on the Chorá of Patmos, within the 3D Past project, funded by the European Creative Europe program. The first part illustrates the results of the research concerning the analysis of the material components of the architectural heritage of Patmos: the urban structure, the evolution of the main architectural typologies, the feature of the main building systems. The second part of the paper presents the application of the Heritage Impact Assessment (HIA), a tool for the management of site transformations and in particular for identifying, forecasting and evaluating the impact of potential development on the Outstanding Universal Value (OUV) of the properties. In the case of Patmos the application of HIA can provide an important contribution to manage changes and future transformations in order to preserve the cultural significance of the site and ensure its sustainable development

Frenkel Excitons in Tubular Geometries

Molecular aggregates with tubular geometries are chemically interesting because of their light‐harvesting and energy transfer capabilities. Nature utilizes these characteristics in the form of chloroplasts in green bacteria. These tubular aggregates absorb photons at specific sites, and then transfer the absorbed energy to acceptor sites in order to use that energy for photosynthesis. In order to investigate the dynamics of such energy transfers, a computational simulation was developed to generate molecular aggregates and model the movement of energy from a donor molecule to an acceptor molecule. The model utilizes Frenkel excitons, which regulate transport through fluctuations in the molecules’ energy levels. Three geometries were investigated: a single‐walled nanotube, a double‐walled nanotube, and a double-helix. It was found that the rate of exciton transport was fastest in the helices and slowest in the double-­walled nanotube, and that the exciton becomes far more delocalized in a double-­helix than in a nanotube. Helices seem to be better suited to high-­speed energy transfer, though whether helical aggregates are plausible experimentally remains untested.Bachelor of Scienc

A collaborative Web App to foster a knowledge network on vernacular heritage, craftspeople, and sustainability

[EN] Vernacular architecture provides extraordinary technological and typological solutions, which are the result of a complex system of knowledge that has evolved through trial and error, in a deep connection to the environmental, social, economic and cultural contexts. The goal of the study presented here is to propose a tool able to organise vernacular knowledge, both tangible and intangible, by systematising principles, strategies, design models and solutions in order to be more easily shared, transmitted and employed in the design of new sustainable architecture. The tool, which is developed as part of the project "VerSus+ / Heritage for People" (Creative Europe Program), is a collaborative Web Application able to map solutions and models from vernacular architecture, and to associate and classify them with sustainable strategies. In addition to physical objects (cultural landscapes, urban, typological and technological solutions), the App will also map the people involved in the knowledge management of vernacular architecture: craftspeople and professionals in the field of vernacular architecture enhancement and conservation. This tool can catalogue solutions and knowledge from different branches of vernacular architecture, and make it available to a large audience, such as professionals, researchers, artisans and citizens, who can also directly contribute to the growth of the vernacular database by adding new information and solutions to the App. The idea is to have a user friendly and easy to consult App, able to suggest new solutions to contemporary design problems, based on the observation of similar past problems, so that sustainable models developed in the past can be adapted to design and construct a more appropriate architecture for the future.Ammendola, J.; Dipasquale, L.; Ferrari, EP.; Mecca, S.; Montoni, L.; Zambelli, M. (2022). A collaborative Web App to foster a knowledge network on vernacular heritage, craftspeople, and sustainability. En Proceedings HERITAGE 2022 - International Conference on Vernacular Heritage: Culture, People and Sustainability. Editorial Universitat Politècnica de València. 703-710. https://doi.org/10.4995/HERITAGE2022.2022.1495170371

Nonlinear optical signatures of ultraviolet light-induced ring opening in α -terpinene

Photoinduced electrocyclic ring opening reactions in conjugated cylcoalkenes are among the most elementary processes in organic chemistry. One prototypical ring opening reaction transforms cyclohexadiene into hexatriene. It is known that a sequence of sub-100 fs internal conversion transitions precedes bond breaking in cyclohexadiene and some of its derivatives. However, these excited state dynamics have never been directly monitored in solution because of insufficient time resolution. Here we aim to uncover the extraordinary photophysics behind related ultrafast internal conversion processes in a derivative of cyclohexadiene, α-terpinene (α-TP), solvated in cyclohexane. Transient absorption anisotropy experiments conducted with 20 fs laser pulses at 267 nm expose non-exponential depopulation kinetics for the ππ* electronic state of α-TP. Our data show that population transfer rapidly accelerates within the first 100 fs after photoexcitation. In addition, recurrences in two-dimensional photon echo (2DPE) line shapes reveal strong vibronic coupling in a normal mode near 523 cm−1, which involves torsions of the C=C bonds and hydrogen out-of-plane (HOOP) wagging on a vinyl group. With the support of several experiments, we hypothesize that the excited state wavepacket in α-TP undergoes several recurrences in the C=C stretching coordinate before displacement along the C=C torsion/vinyl HOOP coordinate finally sets it free from the Franck–Condon region of the potential energy surface. The unconfined wavepacket departs the ππ* electronic state by way of a conical intersection with a lower energy excited state. The present observations are made possible by recent improvements to both the time resolution and detection sensitivity of our experimental setup. This work demonstrates that it is now possible to acquire 2DPE signals in the deep ultraviolet, which are comparable with high-quality measurements in the visible spectral region. These technical developments open the door to studies of many beautiful models for elementary chemical dynamics

Cirrhosis in a captive sun bear (Helarctos malayanus): a case report

El oso malayo (Helarctos malayanus o Ursus malayanus) es el más pequeño de los osos existentes en la actualidad. Su hábitat natural son las selvas tropicales del sudeste de Asia. Son omnívoros, se alimentan de brotes de plantas, raíces, frutas, bayas y semillas, como así también de pequeños mamíferos, aves, insectos e incluso miel de abejas. No presentan período de hibernación, pero en condiciones naturales durante la época de invierno, debido a la carencia de alimentos, se mantienen a partir de las reservas corporales grasas acumuladas en otoño (perÍodo de hiperalimentación).Facultad de Ciencias Veterinaria

Mapas conceituais: como uso da metodologia de ensino e pesquisa para o estudo de desenvolvimento de projeto arquitetônico / Conceptual maps: how to use the teaching and research methodology for the architectural project development study

Esta pesquisa pretendeu aplicar uma nova metodologia de ensino com o estudo dos “mapas conceituais”, no qual esta ferramenta é capaz de organizar e mostrar o conhecimento de forma muito clara, além de demonstrar como as informações interagem.

Projeto de extensão – acessibilidade em foco: ruas acessíveis para todos / Extension project - accessibility in focus: streets accessible to all

O projeto tem como propósito dar continuidade ao projeto Cesmac Acessível, no qual foi apresentado uma proposta visando melhores condições de acessibilidade aos indivíduos P.N.E de acordo com a norma ABNT NBR 9050 – 2015, desenvolvendo calçadas adequadas para uso no ambiente do CESMAC, na Rua Cônego Machado. Neste projeto os espaços acessíveis estenderam-se as ruas, da Harmonia, Rad. Odete Pacheco e Jornal de Alagoas, beneficiando a todos os usuários com passeios, equipamentos e mobiliários inclusivos. A proposta em questão segue as normas determinadas pela lei.