Standardization of Manikkadai Nool

Aim of the study is to standardize Manikkadai nool- a siddha diagnostic tool. • Due to lack of theoretical evidences, it becomes a quite difficult to standardize Manikkadai in a better way. But the author tried best to present most possible outcome regarding Manikkadai nool. • 100 patients were randomly selected from OPD with age group of 18 to 60 years at Government Siddha Medical College, Palayamkottai, Tirunelveli according to the inclusion and exclusion criteria. • 4 threads were used to assess Manikkadai nool to analyze if there is any variation between threads. • Manikkadai viratkadai alavu were taken in both Metacarpophalangeal and Interphalngeal joints of palmar and dorsal surfaces of the hand. • Like this a total of 96 measurements were taken in each participant, to standardize the Measuring side (Right and Left), Measuring surface (Palmar and Dorsal), Measuring joints (MCP and IP), Measuring thread of Manikkadai nool (Pattu, Twine, Swing and Panjavarna thread). • Along with Manikkadai, Other siddha diagnostic procedures such as Ennvagai thervu was also included to add strength to the study. • Based on the statistical analysis, Observation and results: • PANJAVARNA NOOL gives better results when compared to other threads used such as Pattu nool, Twine thread, Swing thread. • Measurements of Both PALMAR SURFACE and DORSAL SURFACE presents better results. • Measuring finger breadths in METACARPOPHALANGEAL JOINTS gives better results than interphalangeal joint. • OPPOSITE SIDE MEASUREMENT i.e. measuring Manikkadai circumference and viratkadai (Finger breadth) of opposite side gives better results than the same side. CONCLUSION: On standardizing Manikkadai nool, Panjavarna nool, both Palmar surface & Dorsal surface and Metacarpophalangeal joint were considered as best when comparing it with symptoms proposed in siddha textual references. Besides that, other siddha parameters such as Naadi and Neikuri also helped in diagnosing a disease in a more efficient way. By this author concluded that siddha diagnostic tools can be also used confirmatory diagnostic tools when used in a proper and efficient way. So further studies should be needed to strengthen Siddha diagnostic parameters. The author encourage further studies on Manikkadai nool by taking this study as preliminary one because further studies will be needed prior to use these methods in clinical practice

BIOFILM FORMATION AND QUORUM SENSING ANALYSIS OF UROPATHOGENIC MULTIDRUG RESISTANCE ESCHERICHIA COLI

Objective: Escherichia coli (E. coli) are gram-negative facultative anaerobes which are commonly found in the lower intestine. Biofilm production in E. coli promotes colonization and leads to an increase rate of infections, and such infections may be difficult to treat as they exhibit multidrug resistance (MDR). Methods: 50 strains of uropathogenic E. coli were collected from Clinical Microbiology laboratory at Saveetha medical college and hospital for a time period of 3 mo. Strains were identified by conventional biochemical methods. Biofilm formation and quorum sensing analysis were performed by the Microtitre plate method and Thin Layer Chromatography method (TLC), respectively. Results: In this study, 46 (92%) of E. coli strains were strong, 3(6%) were intermediate and 1(2%) were weak biofilm producers. From TLC analysis, 34 (68%) of the strains produced Acyl Homoserine Lactone molecules. Out of which, 16 isolates were shown unknown analytes of Retardation factor (Rf) value greater than 1. The Rf values identified were 3 unsubstituted C4 (5), 3 unsubstituted C6 (3), 3 oxo C8 (3), 3 oxo C4 (4), 3 oxo C6 (2), 3 oxo C1 (1). Conclusion: In this study, 100% of isolates were biofilm producers. Of which 18 strains produced known Acyl Homoserine Lactone molecules and 16 isolates produced unknown analytes. Thus, quorum sensing molecules plays a major role in biofilm formation

A Novel estimation and Correction of Channel errors in LTE SYSTEMS

The increase in the number of RF devices and the requirement for large data rates places major role in increasing demand on bandwidth. This necessitates the need for RF communication systems with increased throughput and capacity. MIMO-OFDM is one way to meet this basic requirement. OFDM is used in many (WCD) wireless communication devices and offers high spectral efficiency and resilience to multipath channel effects. Though OFDM is very sensitive to synchronization errors, it makes the task of channel equalization simple. MIMO utilize the multiple antennas to increase throughput without increasing transmitter power or bandwidth. This project presents an introduction to the (MPC) multipath fading channel and describes an appropriate channel model. Many modulation schemes are presented (i.e. BPSK, QPSK, QAM) that are often used in Conjunction with OFDM. Mathematical modeling and analysis of OFDM are given along with a discrete implementation common to modern RF communication systems. Synchronization errors are modeled mathematically and simulated, as well as techniques to estimate and correct those errors at the receiver accurately

Crystal structure of 8-hydroxyquinolin-ium 2-carboxy-6-nitrobenzoate mono-hydrate

The authors thank SAIF, IIT Madras for the data collection.Peer reviewedPublisher PD

Studies on crossability in cashew (Anacardium occidentale L.) genotypes

Successful hybridization primarily depends on the crossability of the parents involved as well as development of the F1 hybrids and their derivatives. In the present study, 12 crosses were attempted to study the crossability relationship among cashew genotypes. Among the crosses, the highest crossability was recorded in the cross H-303 x VTH 711/4 (17.16%), whereas, high rate of abscission of young fruits was observed in crosses involving NRCC Selection -2 as female parent. The genotype VTH 711/4 has shown substantially high per cent of crossability and better nut set with different genotypes of cashew

Recent advances in starch–clay nanocomposites

Biological nanocomposites are a valuable addition to the existing nanocomposite materials and eventually can substitute petroleum-based composite materials in numerous applications due to their inherent advantages such as biodegradability, eco-friendliness, low cost, and easy availability to name a few. Recently, polymer–clay nanocomposites have achieved much more attention due to their enhanced properties such as size dispersion and significant enhancement in physicochemical and mechanical properties in comparison to the pure polymer systems. Among various biopolymers, starch is one of the most abundant natural polymers on the earth and is highly valuable due to its chemical and physical properties. Starch polymer has highly increased potential as an alternative to petroleum-based materials. However, starch cannot be used alone and starch–clay nanocomposite has emerged as a new potential green sustainable material. This article focuses on recent progress in starch-based nanocomposites with particular emphasis on starch–clay nanocomposite preparation, properties, and applications

Genetic relatedness among developing seeds and intra fruit seed abortion in Dalbergia sissoo (Fabaceae)

Dalbergia sissoo, a wind-dispersed tropical tree, exhibits high intrafruit seed abortion. Of the four to five ovules in the flower, generally one and occasionally two or three develop to maturity. It has been proposed that the seed abortion is a consequence of intense sibling competition for maternal resources and that this competition occurs as an inverse function of the genetic relatedness among the developing seeds. Accordingly, developing seeds compete intensely when they are genetically less related but tend to develop together when genetically more related. We tested this hypothesis by comparing the genetic similarity among the pairs of seeds developing within a pod with that among (a) random pairs from the pool of all seeds, (b) random pairs from single-seeded pods, and (c) random pairs from two-seeded pods, using both randomly amplified polymorphic DNA (RAPD) and isozymes in five trees. We found that the pairs of seeds developing within a pod are genetically more similar than any random pairs of seeds in a tree. Thus the formation of two-seeded pods appear to be associated with increased genetic relatedness among the developing seeds. We discuss the results in the context of possible fitness advantages and then discuss the possible mechanisms that promote tolerance among related seeds

Hydrolysis of proteinaceous tannery solid waste for the production of extracellular acidic protease by Selenomonas ruminantium

The objective of this study was to produce protease from Selenomonas ruminantium using animal fleshing (ANFL), an untanned tannery solid waste as the sole protein source. Optimization of the minimal medium composition for the production of protease was carried out by a statistical approach using response surface methodology (RSM) which includes the variables such as NH4Cl, K2HPO4, KH2PO4 and NaCl. The isolate was found to produce maximum protease at pH 6 and at a temperature of about 40°C. Protease was purified 56 fold with a total yield of 28.14%. The enzyme was found to be monomeric having a molecular weight around 53 kDa. The purified enzyme was stable at a pH of about 4 revealing its acid protease nature and was also found to be stable up to 40°C. The enzyme was activated by divalent cations like Ca2+ and Mg2+ and inhibited by dithiothreitol (DTT), where the latter suggested its cysteine protease nature. The enzyme had good stability in the presence of non-ionic surfactants like tween 20, tween 40, tween 80 and triton X100 and also in the presence of solvents like methanol, ethanol and isopropanol. These characteristics reveal the potential of the enzyme for different industrial applications.Keywords: Acid protease, animal fleshing, optimization, response surface methodology (RSM), Selenomonas ruminantiu

Project management tool

A system for managing a project that includes multiple tasks and a plurality of workers. Input information includes characterizations based upon a human model, a team model and a product model. Periodic reports, such as a monthly report, a task plan report, a budget report and a risk management report, are generated and made available for display or further analysis. An extensible database allows searching for information based upon context and upon content