Theoretical interpretation of scanning probe images of molecules on surfaces

Scanning tunnelling microscopy (STM) and atomic force microscopy (AFM) can produce images of molecules with extremely high resolution. However, Claims that dynamic force microscopy has the capability to resolve intermolecular bonds in real space continue to be vigorously debated. Several studies have now shown that tip flexibility, especially at very close tip-sample separations, is responsible for the striking intra- and intermolecular resolution observed with various scanning probe microscopy techniques. The apparent intermolecular features can be observed with dynamic force microscopy even when no bonding interaction is present, suggesting that such features are in fact an artefact and cannot be interpreted as a real-space image of an intermolecular bond. We have studied the interaction between fullerene (C60) molecules using a sum of pairwise Lennard-Jones (12-6) potentials, and investigated how flexibility in the tip can produce a bond like feature between the molecules in a C60 island where there is no chemical bond present except the weak van der Waals force. We also investigate how the potential between the molecules is dependent on their relative orientations. For a given configuration of the tip and the sample molecules, our results allow us to predict the form of the intermolecular potential that would be observed using non contact atomic force microscopy (NC-AFM). Our study on the Si(111)-(7x7) reconstructed surface using the same model provides a better understating on the origin of ‘sub-atomic’ contrast observed in experiment suggesting that the contrast can arise from a flexible tip exploring an asymmetric potential created due to the positioning of the surrounding surface atoms. We have also simulated NC-AFM images of 2D bi-isonicotinic acid lattice using the same model. The geometry of the lattice have been optimized using DFT before simulating AFM images. Simulation results are in a good agreement with the experiment. The theoretical work is accompanied by a variety of experimental results obtained by the group of Prof Philip Moriarty at the University of Nottingham

Phytochemical investigations of Campsis radicans L.

Petroleum ether, dichloromethane and ethyl acetate soluble fractions were obtained through partitioning the crude methanolic extract of the leaves of Campsis radicans L. (Family. Bignoniaceae) followed by the chromatographic separation of secondary metabolites from them. A total of five triterpene compounds i.e., corosolic acid methyl ester (1), β-amyrin (2), arjunolic acid (3), maslinic acid (4) and 28-O-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl]-2α,3α,19α-trihydroxy-12-en-28-ursolic acid (5) were isolated from the dichloromethane fractions and their structures were characterized by 1H NMR spectroscopy and compared the NMR data with published values

On the Convergence of the Homotopy Analysis Method for Inner-Resonance of Tangent Nonlinear Cushioning Packaging System with Critical Components

Homotopy analysis method (HAM) is applied to obtain the approximate solution of inner-resonance of tangent cushioning packaging system based on critical components. The solution is obtained in the form of infinite series with components which can be easily calculated. Using a convergence-control parameter, the HAM utilizes a simple method to adjust and control the convergence region of the infinite series solution. The obtained results show that the HAM is a very accurate technique to obtain the approximate solution

Human Behaviour and Responses Challenge towards Emergence of Infectious Diseases: E.coli clinical isolate

Consumption of undercooked ground beef is the most common route of transmission of verotoxin-producing E.coli. It is estimated that non-O157 verotoxigenic E.coli (VTEC) can cause diarrhea.The sample was isolated from Universiti Malaya Medical Centre. All the isolates were identified using agarose gel electrophoresis method. This study aims to detect the verotoxin genes and detect the link or involvement of plasmids with these verotoxin genes.  Therefore, this study will contribute to shed new light on resolving the significant and global problem of diarrheal disease caused by this particular pathogenic organism and help in improvising novel therapeutic approaches to improve human healthcare.© 2016. The Authors. Published for AMER ABRA by e-International Publishing House, Ltd., UK. Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies, Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.Keywords: E.coli; non-0157; plasmid profil

The One Step Optimal Homotopy Analysis Method to Circular Porous Slider

An incompressible Newtonian fluid is forced through the porous of a circular slider which is moving laterally on a horizontal plan. In this paper, we introduce and apply the one step Optimal Homotopy Analysis Method one step OHAM to the problem of the circular porous slider where a fluid is injected through the porous bottom. The effects of mass injection and lateral velocity on the heat generated by viscous dissipation are investigated by solving the governing boundary layer equations using one step optimal homotopy technique. The approximate solution for the coupled nonlinear ordinary differential equations resulting from the momentum equation is obtained and discussed for different values of the Reynolds number of the velocity field. The solution obtained is also displayed graphically for various values of the Reynolds number and it is shown that the one step OHAM is capable of finding the approximate solution of circular porous slider

Intermolecular artifacts in probe microscope images of C60 assemblies

Claims that dynamic force microscopy has the capability to resolve intermolecular bonds in real space continue to be vigorously debated. To date, studies have been restricted to planar molecular assemblies with small separations between neighboring molecules. Here we report the observation of intermolecular artifacts over much larger distances in 2D assemblies of C60 molecules, with compelling evidence that in our case the tip apex is terminated by a C60 molecule (rather than the CO termination typically exploited in ultrahigh resolution force microscopy). The complete absence of directional interactions such as hydrogen or halogen bonding, the nonplanar structure of C60, and the fullerene termination of the tip apex in our case highlight that intermolecular artifacts are ubiquitous in dynamic force microscopy

The Potential Short- and Long-Term Disruptions and Transformative Impacts of 5G and Beyond Wireless Networks: Lessons Learnt from the Development of a 5G Testbed Environment

The capacity and coverage requirements for 5 th generation (5G) and beyond wireless connectivity will be significantly different from the predecessor networks. To meet these requirements, the anticipated deployment cost in the United Kingdom (UK) is predicted to be between £30bn and £50bn, whereas the current annual capital expenditure (CapEX) of the mobile network operators (MNOs) is £2.5bn. This prospect has vastly impacted and has become one of the major delaying factors for building the 5G physical infrastructure, whereas other areas of 5G are progressing at their speed. Due to the expensive and complicated nature of the network infrastructure and spectrum, the second-tier operators, widely known as mobile virtual network operators (MVNO), are entirely dependent on the MNOs. In this paper, an extensive study is conducted to explore the possibilities of reducing the 5G deployment cost and developing viable business models. In this regard, the potential of infrastructure, data, and spectrum sharing is thoroughly investigated. It is established that the use of existing public infrastructure (e.g., streetlights, telephone poles, etc.) has a potential to reduce the anticipated cost by about 40% to 60%. This paper also reviews the recent Ofcom initiatives to release location-based licenses of the 5G-compatible radio spectrum. Our study suggests that simplification of infrastructure and spectrum will encourage the exponential growth of scenario-specific cellular networks (e.g., private networks, community networks, micro-operators) and will potentially disrupt the current business models of telecommunication business stakeholders - specifically MNOs and TowerCos. Furthermore, the anticipated dense device connectivity in 5G will increase the resolution of traditional and non-traditional data availability significantly. This will encourage extensive data harvesting as a business opportunity and function within small and medium-sized enterprises (SMEs) as well as large social networks. Consequently, the rise of new infrastructures and spectrum stakeholders is anticipated. This will fuel the development of a 5G data exchange ecosystem where data transactions are deemed to be high-value business commodities. The privacy and security of such data, as well as definitions of the associated revenue models and ownership, are challenging areas - and these have yet to emerge and mature fully. In this direction, this paper proposes the development of a unified data hub with layered structured privacy and security along with blockchain and encrypted off-chain based ownership/royalty tracking. Also, a data economy-oriented business model is proposed. The study found that with the potential commodification of data and data transactions along with the low-cost physical infrastructure and spectrum, the 5G network will introduce significant disruption in the Telco business ecosystem

An Action Plan for Adaptation in Bangladesh Agriculture under Climate Change

This report is the outcome of a study titled 'An Action Plan for Adaptation in Bangladesh Agriculture under Climate Change', carried out with support from the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS). This report prepared by the Center for Environmental and Geographic Information Services (CEGIS) delineates an action plan to prioritize adaptation options after considering the inputs by experts and scrutiny by stakeholders. It aims to promote precision agriculture and commercialization of crop agriculture with strong institutional and financial footing to tackle climate change