Role of Social Media in Inciting the Genocidal Acts: A Case Study on Myanmar’s Rohingya

For years, security forces and the Myanmar army persecuted the Rohingya Muslims, under the shade of “national security”. In 2018, the New York Times published a report accusing Facebook of spreading hate speech, incitements, propaganda, and inflammatory posts against the Rohingyas. According to the report, approximately 700 people worked in a secretoperation which was started by the military people of Myanmar a few years back. There are debates regarding social media’s involvement, more specifically Facebook’s involvement, in causing genocide. This article thus examines the role of social media in inciting genocide in Myanmar against the Muslim Rohingyas. The core argument is that Myanmar was involved in spreading hate speech and propaganda through social media. Consideringthe role of social media in inciting genocidal acts, this article also proves the Rohingya genocide from the perspective of the 1948 Genocide Convention

Transit Zones

Transit Zones interrogates conceptual and theoretical issues concerning the notion of nomadic transience, where movement, stasis and the peripatetic state converge with time. This photographic based research examines the relationship between the still frame and the moving image and the visual metamorphosis from realism to abstraction in the spatial and temporal dimensions of terrestrial places and non-places. Transit Zones identifies isolates, preserves and presents a moment taken from a continuum; a journey into contemporary spaces to engage viewers at a visceral level. Still or static photographic images within Transit Zones observe the state of transit and the movement encountered in transit; inscribing this state of being somewhere else, in another country, another time and place, taking a momentary glimpse of the world, and seeing it phenomenologically to make meaning of the experience. As John Berger states, the true content of a photograph is invisible, for it derives from a play, not with form, but with time. One might argue that photography is as close to music as to painting. Objects recorded in any photograph (from the most effective to the most commonplace) carry approximately the same weight, the same conviction. What varies is the intensity with which we are made aware of the poles of absence and presence. Between these two poles photography finds its proper meaning. The most popular use of the photograph is as a memento of the absent. Here the state of transit or peripatetique, by its very nature, transforms the real into the state of the unknown, offering a dreamlike quality, as the past resonates in the now. As anthropological places of consumption and communication are photographed, we are presented with a memory, a new reality, translated through movement. Transit Zones is this state of transit. Central to this research are the symbiotic relationship between the still frame and the moving image, stasis and movement, time and motion, past and present and the selected moment of transience revealed by the narrative of the photograph. The affect of evolving technologies on the transmission of the image and the symbiotic relationship between travel, movement, speed and perception revealing how nomadic wanderings can change our perception of time. The visual presentation and preservation of time is pivotal within Transit Zones research, from the pictorial to abstraction and stasis to movement and the relationship with time and photographic representation

Aplikasi Rekomendasi Resep Masakan Khas Indonesia bagian Timur Menggunakan Metode Collaboration Collective Intelligence dan Slope One

Resep makanan penting dalam komposisi hidangan, dan juga tidak hanya secara fisik tetapi beberapa dibutuhkan digital. Jadi pengguna tidak perlu menyimpan buku resep yang telah dibeli untuk menemukan resep. Dari situs web yang memberikan rekomendasi untuk digital panduan resep adalah dapurSiapsaji. Aplikasi ini membantu pengguna untuk mencari resep hanya dengan memasukkan bahan dari makanan yang dimiliki oleh pengguna. Dan itu akan menghasilkan daftar menu atau dengan kata lain daftar hidangan menggunakan bahan yang dimasukkan sebelumnya pengguna. Dan ada juga rekomendasi terkait setelah membuka salah satu resep setelah pencarian. Tidak hanya itu, situs web ini juga dapat memberikan kebebasan untuk berinovasi, dengan cara semua pengguna dapat mengisi resep baru sesuai dengan inovasi dan kreasi itu sendiri. Kemudian resepnya akan dipublikasikan dan dibaca oleh publik. Kolektif Kecerdasan Kolektif dan Kemiringan Satu metode ini diimplementasikan dalam desain desain aplikasi ini

PENGGUNAAN ALAT BANTU JALAN SEBAGAI FAKTOR RESIKO PERASAAN TAKUT JATUH PADA LANSIA DI KOTA DEPOK

Penurunan fungsi sistem muskuluskeletal pada lansia berakibat pada meningkatnya kejadian jatuh. Hal tersebut menimbulkan perasaan takut jatuh lansia. Penggunaan alat bantu jalan merupakan salah satu faktor resiko peningkatan perasaan takut jatuh. Penelitian ini bertujuan untuk menganalisis hubungan antara alat bantu jalan dengan perasaan takut jatuh. Desain penelitian yang digunakan adalah cross sectional dengan melibatkan 111 lansia di Kota Depok dengan menggunakan multistage random sampling. Perasaan takut jatuh dinilai dengan menggunakan instrument Falls Efficacy Scale- International (FES-I) dan analisis bivariat menggunakan uji statistic chi square. Hasil penelitian menunjukan ada hubungan antara penggunaan alat bantu jalan dengan perasaan takut jatuh (p value 0,0001). Perawat perlu mengetahui cara melakukan skrining dan mengenal faktor resiko perasaan takut jatuh pada lansia. &nbsp

Assessing the Participants of UNDANA Teacher Pro Profiles with Digital-Based Learning Model; Cat. 1, 2022

This study aims to profile teachers in the 1st category of Undana Teacher Professional Education in 2022 using a digital-based learning model. The expected results are the right model in evaluating digital-based learning models to be ready to become professional teachers, graduates from Category I Teacher Professional Education Participants in 2022 at Nusa Cendana University, Kupang, East Nusa Tenggara. Conditions in the field show that student learning strategies and activities play a very important role in digital-based learning, where students sometimes lack concentration and are less skilled in learning activities with digital-based models. The research uses qualitative methods and aims to evaluate the effectiveness of digital-based learning models in preparing teachers for professionalism. Research innovations at the theoretical level, for the development of studies on population mobility, who work as teachers, practical levels for regions of origin, the potential for remittances of migrants between regions in NTT, and their impact on destination areas. The design of this study was carried out in two stages within a span of 1 year of research procedures in the first semester: field observations which were exploratory studies of learning strategies for In-service PPG students in Kupang City and its surroundings. In various study programs where learning uses Digital-based. Followed by the preparation of a draft field observation report. Seminars or workshops around the effect of full IT/Digital use between learning strategies and Digital mastery which are still minimal/insufficient in the 2 (two) PPG Study Programs referred to above and with reporting. The second semester, Conducting Interactive Analysis of the Milles and Humburman model where IT media learning strategies with Online learning strategies affect the ability to learn to operate a Computer and continue with paying attention to Digital students high ability to operate Computers / IT in lectures at PPG Undana

Isolasi Mikroba Dari Air Asam Tambang Pada Area Pertambangan Tembaga Di Pulau Wetar, Provinsi Maluku

This research was conducted to find bacteria from the genus Acidithiobacillus ferrooxidans which isolated from mine acid water in the copper mining area on Wetar Island, Maluku Province. This bacterium will be utilized in the biohidrometallurgical process (bioleaching) for copper extraction in mining area. The results of this study indicate that bacteria can be isolated from mine acid water samples by enrichment method that was use liquid media from Leathen which is optimized using Trypton Soya Broth (TSB) and bacterial growth on solid media. The presence of Thiobacillussp bacteria was confirmed by the results of gene analysis using a 16S rRNA sequence showing the presence of mixed bacterial colonies but not a single colony

The stabilisation of purified, reconstituted P-glycoprotein by freeze drying with disaccharides

The drug efflux pump P-glycoprotein (P-gp) (ABCB1) confers multidrug resistance, a major cause of failure in the chemotherapy of tumours, exacerbated by a shortage of potent and selective inhibitors. A high throughput assay using purified P-gp to screen and characterise potential inhibitors would greatly accelerate their development. However, long-term stability of purified reconstituted ABCB1 can only be reliably achieved with storage at -80 °C. For example, at 20 °C, the activity of ABCB1 was abrogated with a half-life of <1 day. The aim of this investigation was to stabilise purified, reconstituted ABCB1 to enable storage at higher temperatures and thereby enable design of a high throughput assay system. The ABCB1 purification procedure was optimised to allow successful freeze drying by substitution of glycerol with the disaccharides trehalose or maltose. Addition of disaccharides resulted in ATPase activity being retained immediately following lyophilisation with no significant difference between the two disaccharides. However, during storage trehalose preserved ATPase activity for several months regardless of the temperature (e.g. 60% retention at 150 days), whereas ATPase activity in maltose purified P-gp was affected by both storage time and temperature. The data provide an effective mechanism for the production of resilient purified, reconstituted ABCB1

Bal kamrai deformáció cardialis könnyűlánc-amyloidosisban és hypereosinophilia-szindrómában. Eredmények a MAGYAR-Path Tanulmányból = Left ventricular deformation in cardiac light-chain amyloidosis and hypereosinophilic syndrome Results from the MAGYAR-Path Study

Absztrakt: Bevezetés: A hypereosinophilia-szindróma (HES) és az immunglobulinkönnyűlánc-amyloidosis (ALA) két ritka hematológiai betegség, melyek cardialis eltérésekkel járnak együtt. Célkitűzés: A jelen vizsgálat célja a HES- és ALA-betegek bal kamrai (BK-i) deformációs paramétereinek összehasonlító vizsgálata volt háromdimenziós speckle-tracking echokardiográfia (3DSTE) segítségével. Módszer: A vizsgálatok során 10 HES-beteg (átlagos életkor: 60,9 ± 14,7 év) és 19 ALA-ban szenvedő páciens (átlagos életkor: 63,4 ± 7,8 év, 13 férfi) eredményeit elemeztük. Kontrollcsoportként 13, korban és nemben egyeztetett, egészséges felnőtt szolgált (átlagos életkor: 59,2 ± 4,3 év, 5 férfi). Valamennyi esetben teljes körű kétdimenziós Doppler-echokardiográfiás vizsgálat készült 3DSTE-vel kiegészítve. Eredmények: A kontrollcsoporthoz képest az ALA-betegcsoportban mért valamennyi basalis szegmentális BK-i strain szignifikánsan alacsonyabbnak mutatkozott. Az ALA-betegek globális és átlagolt szegmentális BK-i longitudinális strain (LS) értékei az egészséges kontrollcsoporthoz hasonlítva szignifikánsan alacsonyabbnak bizonyultak. A HES-betegcsoport és az egészséges kontrollok összehasonlítása során szignifikáns különbséget tapasztaltunk a globális BK-LS tekintetében, míg a szegmentális basalis BK-LS is szignifikánsan alacsonyabbnak bizonyult a HES-betegekben. A HES- és az ALA-betegcsoport értékeit összehasonlítva a basalis BK-i radiális és 3D strain mutatott szignifikáns eltérést. Következtetések: A 3DSTE alkalmas módszer a HES- és az ALA-betegcsoportban a BK-i deformációs mechanika részletes vizsgálatára. Mindkét betegcsoportban jelentős deformációs eltérések tapasztalhatók, ALA fennállása esetén az eltérések kifejezettebbek. Orv Hetil. 2020; 161(5): 169–176. | Abstract: Introduction: Hypereosinophilic syndrome (HES) and immunoglobulin light-chain amyloidosis (ALA) are two, rare haematological disorders associated with cardiac alterations. Aim: The goal of the present study was a comparative assessment of left ventricular (LV) deformational parameters in HES and ALA patients using three-dimensional speckle-tracking echocardiography (3DSTE). Method: In the present study, results of 10 HES patients (mean age: 60.9 ± 14.7 years) and 19 ALA patients (mean age: 63.4 ± 7.8 years, 13 males) were analysed. The control group contained 13 age- and gender-matched healthy adults (mean age: 59.2 ± 4.3 years, 5 males). All patients underwent a complete two-dimensional Doppler echocardiography followed by 3DSTE. Results: All basal segmental LV strains were significantly reduced in ALA patients as compared to the control group. Global and mean segmental LV longitudinal strain (LS) values of ALA patients proved to be significantly decreased as compared to those of the healthy control group. During comparison of HES patients and healthy controls, significant difference could be detected in global LV-LS, while segmental basal LV-LS was also significantly reduced in HES patients. Basal LV radial and 3D strains showed significant differences when parameters of HES and ALA patient groups were compared. Conclusion: 3DSTE is a feasible tool for the detailed assessment of LV deformation in HES and ALA patients. Significant LV deformational abnormalities could be detected in both groups. In the case of ALA, these abnormalities are more prominent. Orv Hetil. 2020; 161(5): 169–176

Comparison of humoral and cellular immune responses in hematologic diseases following completed vaccination protocol with BBIBP-CorV, or AZD1222, or BNT162b2 vaccines against SARS-CoV-2

Background: Vaccination has proven the potential to control the COVID-19 pandemic worldwide. Although recent evidence suggests a poor humoral response against SARS-CoV-2 in vaccinated hematological disease (HD) patients, data on vaccination in these patients is limited with the comparison of mRNA-based, vector-based or inactivated virus-based vaccines. Methods: Forty-nine HD patients and 46 healthy controls (HCs) were enrolled who received two-doses complete vaccination with BNT162b2, or AZD1222, or BBIBP-CorV, respectively. The antibodies reactive to the receptor binding domain of spike protein of SARS-CoV-2 were assayed by Siemens ADVIA Centaur assay. The reactive cellular immunity was assayed by flow cytometry. The PBMCs were reactivated with SARS-CoV-2 antigens and the production of activation-induced markers (TNF-α, IFN-γ, CD40L) was measured in CD4+ or CD8+ T-cells ex vivo. Results: The anti-RBD IgG level was the highest upon BNT162b2 vaccination in HDs (1264 BAU/mL) vs. HCs (1325 BAU/mL) among the studied groups. The BBIBP-CorV vaccination in HDs (339.8 BAU/mL ***p < 0.001) and AZD1222 in HDs (669.9 BAU/mL *p < 0.05) resulted in weaker antibody response vs. BNT162b2 in HCs. The response rate of IgG production of HC vs. HD patients above the diagnostic cut-off value was 100% vs. 72% for the mRNA-based BNT162b2 vaccine; 93% vs. 56% for the vector-based AZD1222, or 69% vs. 33% for the inactivated vaccine BBIBP-CorV, respectively. Cases that underwent the anti-CD20 therapy resulted in significantly weaker (**p < 0.01) anti-RBD IgG level (302 BAU/mL) than without CD20 blocking in the HD group (928 BAU/mL). The response rates of CD4+ TNF-α+, CD4+ IFN-γ+, or CD4+ CD40L+ cases were lower in HDs vs. HCs in all vaccine groups. However, the BBIBP-CorV vaccine resulted the highest CD4+ TNF-α and CD4+ IFN-γ+ T-cell mediated immunity in the HD group. Conclusion: We have demonstrated a significant weaker overall response to vaccines in the immunologically impaired HD population vs. HCs regardless of vaccine type. Although, the humoral immune activity against SARS-CoV-2 can be highly evoked by mRNA-based BNT162b2 vaccination compared to vector-based AZD1222 vaccine, or inactivated virus vaccine BBIBP-CorV, whereas the CD4+ T-cell mediated cellular activity was highest in HDs vaccinated with BBIBP-CorV