A scientific attempt to Identify and prioritize the elements effective on the development of strategic thinking in the MAPNA Group Corporation

The purpose of the present study was to identify the effective elements on strategic thinking in the MAPNA Group Corporation whilst its' method of conduction is a mixed one. Once interviews were completed, 44 raw datasets were identified which were transformed into 28 mutual codes that were further categorized in 6 concepts that felt under two categories; ultimately a theory was made. Among the several elements that have been found effective on strategic thinking it can be referred to organizational structure, reward system, organizational culture, organizational agility, organizational outlook, organizational creativity and innovation. In the qualitative part, the population of the present study includes the entire experts and elites of the MAPNA Group Corporation and the identified elements have been subjected to numerical analyses in form of hypotheses. In addition in the quantitative part, the population of the study includes the entire employees of the MAPNA Group Corporation among whom 154 individuals have been selected as the samples of the study. results of the study have shown that the identified elements are not of equal importance and in terms of priority these elements respectively include organizational structure, organizational agility, organizational outlook, organizational creativity and innovationو reward system, organizational culture

The Role of Personality Characteristics in Differentiating Different Family Types

ABSTRACT The current study has investigated differences among different family types based on family process and content model considering personality characteristics. 147 married men and women were asked to answer items of family content and process scales and short version of NEO's personality inventory. Data was analyzed by multivariate analysis of Variance method. Findings showed that there were significant differences among different family types in terms of their personality characteristics, except for Openness to experience. Healthy families reported higher Extraversion, Conscientiousness, and Agreeablenessand lower ones in Neuroticism compared to unhealthy and problematic families. Also, problematic families reported higher Extraversion, Conscientiousness, and Agreeableness and lower Neuroticism in comparison with unhealthy families

THE RELATIONSHIP BETWEEN EMOTIONAL INTELLIGENCE AND ORGANIZATIONAL COMMITMENT AMONG EMPLOYEES OF GOVERNMENTAL ORGANIZATIONS AFFILIATED SUBGROUPS TEHRAN MUNICIPALITY

The purpose of this study was to investigate the relationship between emotional intelligence and organizational commitment among Tehran City municipality staff. The research method is descriptive correlation. The statistical population of the study consisted of all the staff of the districts in Tehran (N = 420). The statistical sample was 201 randomly selected according to the Krejsi-Morgan table among the employees of Tehran's 15-9 district. The research instrument included two questionnaires, emotional intelligence and organizational commitment which had an appropriate validity and reliability. Kolmogorov-Smirnov test and Pearson correlation coefficient were used to analyze the data. Data analysis showed that there was a positive and significant relationship between emotional intelligence and organizational commitment (P <0.05). In explaining the results of this study, it can be concluded that employees with high emotional intelligence, cooperation, creativity and communication between They show a better person, they are able to understand, express and manage their emotions, which affects their attitude towards their work, colleagues, managers, executives, and their commitment to the organization. It is suggested that municipalities take courses To train emotional intelligence for the staff of this collection.  Article visualizations

The effect of MDMA and pentoxifylline drug on bad/bcl-xl gene dosage expression changes on rat liver

        MDMA generally known as ecstasy, have deleterious effects on the serotonergic neurotransmitter system. Recent findings suggest that the liver and brain are major target organs of MDMA-related toxicities. Although most research is being dynamically performed on brain, however, the molecular mechanisms by which MDMA elicits adverse effects in both organs are poorly undrestood.The present study was performed to obtain evidence for molecular mechanism of apoptosis involved in MDMA-induced hepatotoxicity in rat liver after MDMAadministration. Moreover, the antagonistic effect of pentoxifylline was assessed on hepatotoxicity after MDMA administration. In this experimental study, sample size and power in each group were calculated as 10 rats with 95% confidence level and 5% confidence interval. In the study, four experimental groups were selected including Control Normal, MDMA, MDMA+PTX and PTX+MDMA. MDMA was dissolved in PBS and intraperitoneally injected three doses of 7.5mg/kg with two hours gap between doses. Pentoxyfilline also was injected as 100mg/kg, simultaneously with third dose of MDMA. After treatment, total RNA was isolated from liver tissue (5mg). Absorbance at 260nm, 280nm and 230nm were measured and immediately reverse transcription was performed. Included target genes were BAD and BCL-XL as pro-apoptotic and anti-apoptotic gene, respectively. After set up and validation, Real-Time PCR were performed and obtaining data were statistically analyzed to determine significantly differences between groups. Using Real-Time quantitative PCR results, BCL-XL gene expression ratio significantly increased in MDMA+PTX group. Moreover, BAD gene expression ratio increased and up-regulated in PTX+MDMA group (P-value <0.001).Our study focused on molecular mechanism of MDMA in programmed cell death using gene expression quantification of a pro-apoptotic and anti-apoptoic gene in MDMA-induced hepatotoxocity. The results shown MDMA prompted apoptosis in liver and pentoxifylline protects hepatotoxicity after and befor taking MDMA.

Determination of the association between body image with sexual function and marital adjustment in fertile and infertile Women by path analysis modeling

Abstract Background & Objective: Infertility has several adverse effects on body, psychological and social aspects of women. Otherwise, body image could be a predictor of different behaviors including sexual behavior. Thus, in the present study we aimed to assess the association between body image with sexual function and marital adjustment in fertile and infertile women. Materials & Methods: One-hundred and thirty fertile and 130 infertile women were enrolled in this study. Statistical analysis was performed by using AMOS 18 with structural equation modeling. Results: In fertile women, the strongest path coefficient was related with the effect of body image on general health, while in infertile women, the strongest path coefficient was associated with the effect of body image on sexual function. In both occupying and non-occupying women the strongest path coefficient was related with the effect of body image on general health. In those infertile women who had the supports of their partners, the strongest path coefficient was associated with the effect of body image on sexual function, and in those infertile women who had not the supports of their partners the strongest path coefficient belonged to the effect of sexual function on marital adjustment. Conclusion: Based on our results, it seems that using structural equation modeling in evaluating and recognition of direct, indirect and total effects of the similar model is absolutely necessary and can be a good alternative method instead of regression

Prevalence of micro-aspiration of bile acids in patients with primary lung cancer: A cross-sectional study

BACKGROUND: Lung cancer remains a serious public healthproblem and is the first cause of cancer-related death worldwide. There is some evidence suggests that bile acid micro-aspiration may contribute to the development of lung diseases. This study aimed to assess the prevalence of microaspiration of bile acids in patients with primary lung cancer.METHODS: In a cross-sectional study, 52 patients with primary lung cancer referred to a teaching hospital affiliated with Kerman University of Medical Sciences, Kerman, Iran were enrolled. Patients with pathology-confirmed lung cancer who did not receive specific treatment were included in the present study. All patients underwent bronchoscopy and the levels of bile acid was assessed in their Broncho-Alveolar Lavage (BAL) samples.RESULTS: According to the results, 53.85% of patients were in the age group of 40 to 59 years. Of the participants, 88.46% were male, 82.69% were smokers, and 69.23% were opium addicted. The most common presenting clinical symptoms of patients were heartburn (61.55%), hoarseness (17.31%), and epigastric pain (9.61%), respectively. Ninety-two point thirty two percent of patients had endobronchial lesions in bronchoscopy. Squamous cell carcinoma, small-cell lung carcinoma and adenocarcinoma accounts for 48.08%, 34.61% and 17.31% of all cases of lung cancer, respectively. Bile acids were found in the BAL sample of all patients with primary lung cancer. The mean Bile acids levels in patients were 63.42 (SD=7.03) μmol/Lit.CONCLUSION: According to the results of present study, there was a micro-aspiration of bile acids in all patients with primary lung cancer that may participate in shaping early events in the etiology of primary lung cancer. It seems that developing clinical strategies preventing the micro-aspiration of bile acids into the lungs could remove a key potential trigger in this process

Comparison between doxycycline–rifampin–amikacin and doxycycline–rifampin regimens in the treatment of brucellosis

SummaryBackgroundCombination drug therapy of brucellosis leads to recovery of symptoms, shortening of symptomatic interval, and decrease in morbidity rate, but single drug therapy is associated with more relapse episodes and a higher rate of drug resistance. Different drug combinations have been evaluated in the treatment of brucellosis. Considering the failure of treatment and relatively high rate of relapse of the disease with the World Health Organization's (WHO) recommended therapeutic regimen, we evaluated a new regimen that we assumed would increase the success of treatment and decrease the rate of relapse. In this study we compare the standard regimen of the WHO, doxycycline–rifampin (DR), to triple therapy with doxycycline–rifampin–amikacin (ADR).MethodsTwo hundred and twenty-eight consecutive patients with brucellosis, who attended Hamedan Sina Hospital between 1999 and 2001, whether seen as outpatients or as inpatients, were enrolled in the study. The participants were randomly allocated to the DR group (receiving doxycycline 100mg twice a day and rifampin 10mg/kg body weight/day every morning, both taken orally for eight weeks) or the ADR group (receiving doxycycline 100mg twice a day and rifampin 10mg/kg body weight/day every morning, both taken orally for eight weeks, plus 7.5mg/kg amikacin intramuscularly twice a day for seven days). The patients were checked for the relief of symptoms, drug side-effects, and relapse of disease during the treatment and follow-up.ResultsOf the 228 patients enrolled, eight were withdrawn – four patients from the DR group and four from the ADR group. Of the remaining 220 participants (110 in the ADR group and 110 in the DR group), 107 were male (48.6%) and 113 were female (51.4%). Mean age was 35.7±17 years in the ADR group and 37±18.4 years in the DR group (p=0.5). In the DR group, 97 (88.2%) and in the ADR group, 106 (96.4%) of the patients had relief of symptoms (a significant difference by Chi-square test (p=0.04)). After completion of treatment, and at the sixth month follow-up, nine (9.3%) patients in the DR group and six (5.7%) in the ADR group experienced a relapse of the disease, with no significant difference (p=0.4). Mild side-effects were found in only 10 patients, and none required discontinuation of the therapeutic regimen. Of these patients, four were from DR group and six from ADR group; no significant difference was observed (p=0.7).ConclusionsGiven the fact that the ADR regimen had a higher efficacy and more rapid action in terms of relief of symptoms compared to the DR regimen, and that no significant difference in drug side-effects and disease relapse existed in the patients of either group, adding amikacin to the DR standard treatment regimen seems beneficial

Effects of Alginate Coating Containing Zataria multiflora Essential Oil in the Form of an Emulsion Gel and Nano-emulsion on the Chemical Quality and Sensory Properties of Rainbow Trout Fillet

Fish is often more perishable than most other foodstuffs. Microbial progression, enzymatic activity, and non-enzymatic oxidation of fats reduce the quality of fish and its products. The present study aimed to evaluate the effects of the nano-gel emulsion and emulsion gel of an alginate coating containing Zataria multiflora essential oil (ZMEO) on the chemical and sensorial quality of rainbow trout fillet (Oncorhynchus mykiss) during 16 days of refrigerated storage (4±1°C). The fish fillets were treated with alginate coating, alginate emulsion with different ZMEO concentrations (E0.25%, E0.5%, and E1%), and nano-emulsion with different ZMEO concentrations (N0.25%, N0.5%, and N1%). Afterwards, the fillets were analyzed for chemical changes (pH, TVB-N, TBARS, PV, FFA, and fatty acid profile) and sensory properties (color, texture, flavor, odor, and overall acceptability) on days zero, four, eight, 12, and 16. Data analysis was performed in SPSS version 21 using ANOVA, Bonferroni post-hoc test, and Dunnett T3 test to assess significant differences at P<0.05. The results of chemical analysis showed an increasing trend (pH, TVB-N, TBARS, PV, FFAs, MUFAs, and SFAs) during the storage period (day 16) although the rate was slower in the nano-emulsion treatments. Furthermore, the sensory properties of the samples decreased during the storage period, while using ZMEO in the alginate coating (especially in the nano-emulsion form) showed better results compared to the control. According to the results, the alginate coating containing ZMEO (especially in the nano-emulsion form) could preserve the chemical and sensorial quality of the fresh trout fillets for four days

INVESTIGATION THE ROLE OF MEPXH1 (HIS139ARG) POLYMORPHISM ON NUMBER OF EXACERBATIONS AND DISEASE SEVERITY IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN A SMOKER POPULATION

The purpose of this study was to examine investigation the role of mEPXH1 (His139Arg) polymorphisms on number of exacerbations and disease severity in chronic obstructive pulmonary disease in a smoker population. Chronic obstructive pulmonary disease (COPD) has become the fourth most common single cause of morbidity, and its prevalence is increasing worldwide. It is a syndrome composed of chronic bronchitis, small airways disease (bronchiolitis), and emphysema, in varying proportions between affected individuals. The study was performed cohort and prospectively. The population consist of 213 patients with COPD disease. Genotyping of mEPXH1 was performed using multiplex PCR. Data analysis included, Pearson’s r correlations, regression analysis, ANOVA analyses, Tukey, test for comparison and SPSS software (package of Spss / pc + + ver18). The results showed that there is not relationship between polymorphisms of mEPXH1 and number of exacerbations. According the results, there is not significant relationship between polymorphisms of mEPXH1 and disease severity. Also there is not significant relationship between mEPXH1 and disease in COPD patients on basis parameters of spirometery and oxidative stress in COPD patients