Homosistinurie: beskrywing van 'n geval

Homocystinuria is an inborn error in the methionine metabolic pathway. It is due to an absence of the enzyme cystathionine synthesase and is inherited probably as a result of autosomal recessive transmission. It is characterized by a 'Marfan-like' appearance, ectopia lentis, a marked thrombo-embolic tendency and often mental retardation. Large quantities of methionine and homocystine are present in the blood, and homocystine in the urine. Treatment is not yet clear but a low-methionine diet with cystine supplementation started at an early age holds the most promise. A case of homocystinuria, probably the first in the Republic of South Africa, is described

Friends and Enemies in Athenian Politics

Copyright © The Classical Association 1996The Greeks divided their world into a number of contrasting categories which cut across and dissected each other: Greek and barbarian, slave and free, friend and enemy, insider and outsider, us and them. This essentially bipartite view of the world (although the dualism changed according to circumstance) affected the way Greek society worked, and the way that the Greeks thought about themselves. In this pair of papers, Professor Rhodes and I will be concerned only with one of these oppositions, friends and enemies

Presence and species identity of rumen flukes in cattle and sheep in the Netherlands

The purpose of the study was to gain knowledge about the prevalence and identity of rumen flukes (RF) in cattle and sheep in the Netherlands. Routine faecal examinations of diagnostic submissions between May 2009 and September 2014 showed a mean annual herd or flock RF prevalence of 15.8% for cattle and 8.0% for sheep. Prevalence in cattle was higher after 2012 than before, which may reflect a change in detection method as well as an increase in true prevalence. During November and December 2014, an abattoir survey was conducted to allow for scoring of rumen fluke burden and to obtain specimens for molecular species characterization. Over 8 visits to 5 abattoirs in areas deemed to pose a high risk for trematode infection, 116 cows and 41 sheep from 27 herds and 10 flocks were examined. Prevalence of RF was higher in beef cattle than in dairy cattle and higher in cattle than in sheep. Median fluke burden was >100 specimens per animal for most positive animals. Using a semi-quantitative RF density score as a gold standard, sensitivity and specificity of a modified quantitative Dorsman egg counting method were estimated at 82.6% and 83.3%, respectively. Of 14 collected adult rumen flukes, twelve (8 bovine and 4 ovine specimens) were identified as Calicophoron daubneyi. The other two, of bovine origin, were identified as Paramphistomum leydeni, which was unexpected as in other European countries all recently collected rumen flukes in both cattle and sheep were identified as C. daubneyi. The findings implicate that multiple rumen fluke species, intermediate host species and transmission cycles may play a role in rumen fluke infections in the Netherlands

A preliminary assessment of water partitioning and ecohydrological coupling in northern headwaters using stable isotopes and conceptual runoff models

Funded by European Research Council ERC. Grant Number: GA 335910 VEWA Swedish Science Foundation (SITES) Future Forest Formas (ForWater) SKB the Kempe foundation Environment Canada the Garfield Weston Foundation the Natural Sciences and Engineering Research Council of Canada (NSERC) the Northwest Territories Cumulative Impacts Monitoring ProgramPeer reviewedPublisher PD

The Impact of Isospin Breaking on the Distribution of Transition Probabilities

In the present paper we investigate the effect of symmetry breaking in the statistical distributions of reduced transition amplitudes and reduced transition probabilities. These quantities are easier to access experimentally than the components of the eigenvectors and were measured by Adams et al. for the electromagnetic transitions in ^{26}Al. We focus on isospin symmetry breaking described by a matrix model where both, the Hamiltonian and the electromagnetic operator, break the symmetry. The results show that for partial isospin conservation, the statistical distribution of the reduced transition probability can considerably deviate from the Porter-Thomas distribution.Comment: 16 pages, 8 figures, submitted to PR

Representation theory of some infinite-dimensional algebras arising in continuously controlled algebra and topology

In this paper we determine the representation type of some algebras of infinite matrices continuously controlled at infinity by a compact metrizable space. We explicitly classify their finitely presented modules in the finite and tame cases. The algebra of row-column-finite (or locally finite) matrices over an arbitrary field is one of the algebras considered in this paper, its representation type is shown to be finite.Comment: 33 page

Classification in e-procurement

Three coupled knowledge transfer partnerships used pattern recognition techniques to produce an e-procurement system which, the National Audit Office reports, could save the National Health Service £500 m per annum. An extension to the system, GreenInsight, allows the environmental impact of procurements to be assessed and savings made. Both systems require suitable products to be discovered and equivalent products recognised, for which classification is a key component. This paper describes the innovative work done for product classification, feature selection and reducing the impact of mislabelled data

Are we willing to give what it takes? Willingness to pay for climate change adaptation in developing countries

Climate change adaptation is gaining traction as a necessary policy alongside mitigation, particularly for developing countries, many of which lack the resources to adapt. However, funding for developing country adaptation remains woefully inadequate. This paper identifies the burden of responsibility that individuals in the UK are willing to incur in support of adaptation projects in developing countries. Results from a nationally representative survey indicate that UK residents are willing to contribute £27 per year (or a median of £6 per year) towards developing country adaptation (US$30 and$7 using the World Bank’s purchasing power conversion factors). This represents less than one third of the back-of-the-envelope $100-140 per capita per year that the authors estimate would be needed to raise the$70-100bn per year recommended by the World Bank to fund developing country adaptation. Regressions indicate that WTP is driven mostly by a combination of beliefs and perceptions about one’s own knowledge levels, rather than actual knowledge of climate change. We conclude that, to engage the many different audiences that make up the ‘public’, communication efforts must move beyond the simple provision of information and instead, connect with people’s existing values and beliefs

An eco-climatic framework for evaluating the resilience of vegetation to water deficit

The surge in global efforts to understand the causes and consequences of drought on forest ecosystems has tended to focus on specific impacts such as mortality. We propose an ecoclimatic framework that takes a broader view of the ecological relevance of water deficits, linking elements of exposure and resilience to cumulative impacts on a range of ecosystem processes. This ecoclimatic framework is underpinned by two hypotheses: (i) exposure to water deficit can be represented probabilistically and used to estimate exposure thresholds across different vegetation types or ecosystems; and (ii) the cumulative impact of a series of water deficit events is defined by attributes governing the resistance and recovery of the affected processes. We present case studies comprising Pinus edulis and Eucalyptus globulus, tree species with contrasting ecological strategies, which demonstrate how links between exposure and resilience can be examined within our proposed framework. These examples reveal how climatic thresholds can be defined along a continuum of vegetation functional responses to water deficit regimes. The strength of this framework lies in identifying climatic thresholds on vegetation function in the absence of more complete mechanistic understanding, thereby guiding the formulation, application and benchmarking of more detailed modelling