Challenges in Procurement of Pharmaceuticals in the Ethiopian Health Institutions

Public procurement is crucial to government service delivery. Procurement of Pharmaceuticals in public hospitals has faced challenges that affect service delivery. Public procurement is a key tool to the overall achievements of development goals such as reducing poverty and providing health, infrastructure, education and other services hence immensely contribute to best utilization of public resources. The limited public resources should be properly managed to get the most out of these resources. Despite its importance, limited scientific research has been undertaken to examine the Challenges of procurement in public institutions in the case of Health institutions. This study aimed to describe challenges in procurement of pharmaceuticals in Jimma University Specialized Hospital (JUSH). Specifically, the study sought to describe challenges in regards to the procurement process, procurement planning, staff competency, and information communication technology and procurement organization structure. The study was conducted through a descriptive design of research. The targeted respondents were 146 and comprise of Administration Officers and functional head that are members of tender committee and/or directly/indirectly involved in pharmaceutical procurements, Supply Chain and pharmaceuticals professionals, and pharmacy service professionals, Department heads of service delivery units and nurse heads of service delivery units in Jimma University Specialized Hospital. A structured questionnaire and interview as a data collection instrument were used. The field data were statistically analyzed using descriptive statistics and narrative summary analyses. Findings indicate that lengthy pharmaceuticals procurement process, lack of employee competency ,poor culture of pharmaceuticals procurement planning are the most serious challenges in pharmaceuticals procurement and fully centralization of pharmaceuticals procurement activities and in efficient use of information communication technology are the next most serious challenges in pharmaceuticals procurement Jimma University specialized Hospital. Keywords: Procurement, Challenges, pharmaciuticals, Ethiopia, Health institutions, procurement Organizational structure DOI: 10.7176/IEL/11-2-01 Publication date:June 30th 202

A Story of One\u27s Own: Creative Narratives about Muslim Women in Turkey

Writing fiction within a feminist framework is a helpful way in bringing up women’s issues to a wider readership that is not necessarily familiar with feminist scholarship. Through creative narrative an author can dispel misunderstandings, correct misconceptions and represent underrepresented women who have been rendered invisible or pushed to the margins by hegemonic discourses. My novella tells the story of a group of Muslim women doing community work in Turkey. Navigating their way in contemporary Turkey, these women dispel the upheld literary stereotypes of Muslim women. Through their work and dedication, these women show that they are not victims of a suppressive religion, or escapees from an oppressive culture. Instead they see themselves as participants in a noble cause for the benefit of the wider society. The impetus for their service is drawn from the main sources of their religion: Quran and the example of the prophet Muhammad

Identifying breeding objectives of smallholders/pastoralists and optimizing community-based breeding programs for adapted sheep breeds in Ethiopia

The aim of this thesis was to identify breeding objectives of smallholder and pastoral sheep keepers in Ethiopia (Afar, Bonga, Horro and Menz areas) and to design appropriate community-based breeding plans for genetic improvement of four indigenous sheep breeds. Information on genetics of adaptation in farm animals was reviewed. Two live animals ranking experiments approaches, own-flock and groupanimal ranking, were used to identify sheep breeding objectives. In own-flock ranking, owners paid more attention to production and reproduction performances and behavioral traits (e.g. milk yield, temperament, lamb growth, mothering ability, body size, lambing interval). In group-animal ranking, observable attributes like coat color, tail type, ear size, body size, etc. recurred. Afar (pastoral) and Menz (sheepbarley) sheep breeders, coping with more challenging production environments, considered more attributes compared to the two crop-livestock systems (Bonga and Horro). Four scenarios of ram selection and ram use were compared via deterministic simulation of breeding plans for community-based sheep breeding programs considering the top three most important traits identified. The review work revealed the need to identify the most appropriate and adapted genotypes capable of coping with environmental challenges posed by the production systems or, wherever possible, adapt the environments to the requirements of the animals. In conclusion, both own-flock and group-animal ranking experiments can serve as tools in objective traits identification in production systems without recording practices. Strong selection and short use of rams for breeding were the preferred options. Expected genetic gains are satisfactory but rely on continuous recording

Simulation of Alternative Plans for Community Based Goat Breeding Program in Arid, Semi-Arid and Mixed Production Systems in Ethiopia

On station small ruminant researches in Ethiopia were ineffective due to various factors. As alternative, community based breeding program (CBBP) has emerged. In the current CBBPs, sire side selection only (SN1) is practiced. The objective of the present work was to compare SN1 by simulating alternative breeding scenarios for Abergelle (AB), Centeral Highland (CH) and Woyto-Guji (WG) goat breeds in Ethiopia. Three scenarios including selection on dam side (SN2) in addition to SN1, application of genomic selection (SN3) onto SN1 and use of sires from SN1 for mating in additional flocks (SN4) were simulated and compared with SN1 based on the predicted annual genetic gain (PAGG) and discounted profits. The breeding objective traits or selection criteria were six month weight (6mw, kg) for all breeds, average daily milk yield (ADM, kg) and survival to six month of age (SURV) for AB, litter size at birth (LSB) for CH and WG, litter size at weaning (LSW) for CH and kidding interval (KI, days) for WG. ZPLAN+ software was used for the simulation. The PAGG for 6mw (kg) ranged from 0.087 (SN4) to 0.25 (SN3) for AB where it ranged from 0.47 (SN4) to 0.97 (SN3) for ADM (kg) for same breed. PAGG in 6mw (kg) ranging from 0.13 (SN4) to 0.47 (SN3) and from 0.20 (SN4) to 0.31 (SN3) for CH Gonder and Ambo sites, respectively were simulated whereas this parameter ranged from 0.10 (SN4) to 0.27 (SN3) for WG. The alternative breeding scenarios to SN1 resulted in better PAGGs, especially for 6mw in three of the goat breeds and for ADM in AB. Based on the PAGGs and profitability, we recommend SN2 over SN1. However, SN4 could also be applied, compared to SN1, in view of suitability of addressing emerging demands

Breeding objectives for Red Maasai and Dorper sheep in Kenya—A participatory approach

The Red Maasai sheep breed is under threat due to indiscriminate crossbreeding and strategies are needed to conserve and improve the breed. The aim of this study was to understand farmers’ preferences for important traits of flocks of Red Maasai, Dorper and crosses in two different areas, Amboseli and Isinya, in Kenya. Farmers identified three ewes that represented the best, average, and poorest within its breed group of each farm and gave reasons for their ranking. The most important traits were body size and growth rate and thereafter milk yield. The Red Maasai was preferred for its better reproduction and tolerance against diseases and drought. In the harshest area, Amboseli, all breed groups had about the same body weight, whereas in Isinya, where conditions are better and farmers are more market oriented, Dorper and crosses had superior weights

Correlated response to selection for litter size environmental variability in rabbits' resilience

[EN] Resilience is the ability of an animal to return soon to its initial productivity after facing diverse environmental challenges. This trait is directly related to animal welfare and it plays a key role in fluctuations of livestock productivity. A divergent selection experiment for environmental variance of litter size has been performed successfully in rabbits over ten generations. The objective of this study was to analyse resilience indicators of stress and disease in the divergent lines of this experiment. The high line showed a lower survival rate at birth than the low line (-4.1%). After correcting by litter size, the difference was -3.2%. Involuntary culling rate was higher in the high than in the low line (+12.4%). Before vaccination against viral haemorrhagic disease or myxomatosis, concentration of lymphocytes, C-reactive protein (CRP), complement C3, serum bilirubin, triglycerides and cholesterol were higher in the high line than in the low line (difference between lines +4.5%, +5.6 mu g/ml, +4.6 mg/ml, +7.9 mmol/l, +0.3 mmol/l and +0.4 mmol/l). Immunological and biochemical responses to the two vaccines were similar. After vaccination, the percentage of lymphocytes and CRP concentration were higher in the low line than in the high one (difference between lines +4.0% and +13.1 mu g/ml). The low line also showed a higher increment in bilirubin and triglycerides than the high line (+14.2 v. +8.7 mmol/l for bilirubin and +0.11 v. +0.01 mmol/l for triglycerides); these results would agree with the protective role of bilirubin and triglycerides against the larger inflammatory response found in this line. In relation to stress, the high line had higher basal concentration of cortisol than the low line (+0.2ng/ml); the difference between lines increased more than threefold after the injection of ACTH 1 to 24, the increase being greater in the high line (+0.9 ng/ml) than in the low line (+0.4 ng/ml). Selection for divergent environmental variability of litter size leads to dams with different culling rate for reproductive causes and different kits' neonatal survival. These associations suggest that the observed fitness differences are related to differences in the inflammatory response and the corticotrope response to stress, which are two important components of physiological adaptation to environmental aggressions.This study is supported by the Spanish Ministry of Economy and Competitiveness (MINECO) with the Projects AGL2014-55921, C2-1-P and C2-2-P, and AGL2017-86083, C2-1-P and C2-2-P.Argente, M.; Garcia, M.; Zbynovska, K.; Petruska, P.; Capcarova, M.; Blasco Mateu, A. (2019). 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Haplotype Affinities Resolve a Major Component of Goat (Capra hircus) MtDNA D-Loop Diversity and Reveal Specific Features of the Sardinian Stock

Goat mtDNA haplogroup A is a poorly resolved lineage absorbing most of the overall diversity and is found in locations as distant as Eastern Asia and Southern Africa. Its phylogenetic dissection would cast light on an important portion of the spread of goat breeding. The aims of this work were 1) to provide an operational definition of meaningful mtDNA units within haplogroup A, 2) to investigate the mechanisms underlying the maintenance of diversity by considering the modes of selection operated by breeders and 3) to identify the peculiarities of Sardinian mtDNA types. We sequenced the mtDNA D-loop in a large sample of animals (1,591) which represents a non-trivial quota of the entire goat population of Sardinia. We found that Sardinia mirrors a large quota of mtDNA diversity of Western Eurasia in the number of variable sites, their mutational pattern and allele frequency. By using Bayesian analysis, a distance-based tree and a network analysis, we recognized demographically coherent groups of sequences identified by particular subsets of the variable positions. The results showed that this assignment system could be reproduced in other studies, capturing the greatest part of haplotype diversity