Determinants of Alanine Dipeptide Conformational Equilibria on Graphene and Hydroxylated Derivatives

Citation: Poblete, H., Miranda-Carvajal, I., & Comer, J. (2017). Determinants of Alanine Dipeptide Conformational Equilibria on Graphene and Hydroxylated Derivatives. The Journal of Physical Chemistry B. https://doi.org/10.1021/acs.jpcb.7b01130Understanding the interaction of carbon nanomaterials with proteins is essential for determining the potential effects of these materials on health and in the design of biotechnology based on them. Here we leverage explicit-solvent molecular simulation and multidimensional free-energy calculations to investigate how adsorption to carbon nanomaterial surfaces affects the conformational equilibrium of alanine dipeptide, a widely used model of protein backbone structure. We find that the two most favorable structures of alanine dipeptide on graphene (or large carbon nanotubes) correspond to the two amide linkages lying in the same plane, flat against the surface, rather than the nonplanar ?-helix-like and ?-sheet-like conformations that predominate in aqueous solution. On graphenic surfaces, the latter conformations are metastable and most often correspond to amide?? stacking of the N-terminal amide. The calculations highlight the key role of amide?? interactions in determining the conformational equilibrium. Lesser but significant contributions from hydrogen bonding to the high density interfacial water layer or to the hydroxy groups of hydroxylated graphene also define the most favorable conformations. This work should yield insight on the influence of carbon nanotubes, graphene, and their functionalized derivatives on protein structure

Acceptance of transgenic vegetable oil from different countries of origin in the Araucanía Region, Chile

Considerando el rechazo de los consumidores hacia alimentos genéticamente modificados y que el país de origen es usado como indicador de calidad, se estudió la importancia relativa de la existencia de modificación genética (MG), origen y precio en la compra de aceite de girasol en Temuco, Chile, junto con la identificación y la caracterización de diferentes segmentos de mercado, mediante una encuesta a 400 personas. Utilizando análisis conjunto se determinó que la existencia de MG (36,0%) fue levemente más importante que el origen (33,3%) y el precio (30,7%) en la muestra total, con preferencia hacia el producto sin MG, de origen chileno y al menor precio. Mediante análisis de conglomerados jerárquicos se diferenciaron tres segmentos: el mayoritario (45,5%) dio elevada importancia a la existencia de MG y presentó un alto rechazo hacia el aceite transgénico; el segundo grupo (29,7%) asignó mayor relevancia al precio y acepta aceite argentino; el grupo minoritario (24,8%) otorgó mayor importancia al origen y acepta aceite español. Independientemente de lo anterior, los grupos mostraron mayor preferencia por el aceite chileno. La ausencia de MG en aceite es una condición deseable para una importante proporción de consumidores (45,5%), pero el resto se muestra relativamente indiferente hacia la existencia o ausencia de manipulación genética en este producto.Considering the rejection by consumers of genetically modified foods, and that the country of origin is used as an indicator of quality, a study was done of the relative importance of the existence of genetic modification (GM), the origin and the price in the purchase of sunflower oil in Temuco through a survey of 400 people; at the same time different market segments were identified and characterized. It was determined by conjoint analysis that the existence of GM (36.0%) was slightly more important than country of origin (33.3%) and price (30.7%) in the total sample, with a preference for product with no GM, of Chilean origin and at a lower price. Three segments were distinguished by analysis of hierarchical conglomerates. The majority segment (45.5%) attributed great importance to the existence of GM and presented high rejection of transgenic vegetable oil. The second group (29.7%) assigned greater importance to the price and accepted Argentinean oil. The minority group (24.8%) attributed greater importance to country of origin and accepted Spanish oil. Regardless of the above distinctions, all groups expressed a greater preference for Chilean oil. The absence of GM in vegetable oil is a desirable condition for a large proportion of consumers (45.5%), but the rest were relatively indifferent to the existence or absence of genetic manipulation in this product.Fil: Schnettler, Berta. Universidad de La Frontera (Chile). Facultad de Ciencias Agropecuarias y Forestales. Departamento de Producción Agropecuaria.Fil: Miranda, Horacio. Universidad de La Frontera (Chile). Facultad de Ciencias Agropecuarias y Forestales. Departamento de Producción Agropecuaria.Fil: Sepúlveda, José. Universidad de La Frontera (Chile). Facultad de Educación, Ciencias Sociales y Humanidades. Departamento de Psicología.Fil: Denegri, Marianela. Universidad de La Frontera (Chile). Facultad de Educación, Ciencias Sociales y Humanidades. Departamento de Psicología.Fil: Mora, Marcos. Universidad de Chile. Facultad de Ciencias Agronómicas. Departamento de Economía Agraria

A REFORMA AGRÁRIA COMO INSTRUMENTO DE JUSTIÇA DISTRIBUTIVA NOS MOLDES PROPOSTOS POR JOHN RAWLS

Analisa a Teoria da justiça proposta por John Rawls, especialmente a sua compreensão sobre justiça distributiva. Investiga se a reforma agrária pode ser entendida como um instrumento de realização dessa justiça distributiva, sobretudo em razão de sua fundamentalidade, da função social da propriedade e dos meios dispostos na legislação para a sua implementação. A metodologia adotada quanto ao procedimento foi a pesquisa bibliográfica e legislativa. Ao final, concluiu-se que a reforma agrária tem a capacidade de ressignificar o conceito de propriedade, objetiva contribuir para o desenvolvimento nacional, com a diminuição da pobreza e desigualdades sociais e por isso está alinhada à noção de justiça distributiva nos moldes do pensamento liberal igualitário de John Rawl

UMA LEITURA DWORKINIANA DO CONTROLE JUDICIAL DA REFORMA AGRÁRIA

Analisa se a reforma agrária pode ser levada a efeito por decisões judiciais. Inicia com a Teoria do Direito desenvolvida por Dworkin e sua reflexão sobre o controle judicial de políticas públicas a partir de construção argumentativa que inclui questões morais e propriamente políticas. Em seguida, passa-se ao estudo sobre o que seria a reforma agrária como política pública e como direito fundamental. Por fim, analisa como o Poder Judiciário vem se estruturando para lidar com a questão. Concluiu-se que o Poder Judiciário pode intervir na distribuição de terras, baseando-se em princípios, para salvaguardar direitos fundamentais

KEPENTINGAN JEPANG TERHADAP TIMOR LESTE MELALUI JAPAN INTERNATIONAL COOPERATION AGENCY (JICA) 2002-2012

Japan was a developed country in industry and technology, this was really support Japan in giving aids to developing countries, through ODA (Official Development Assistent) aid framework. These AID gave to developing countries that facing various problems, such as poverty, starvation, and insufficient health and education services, with agreement between both of them. Timor Leste was one of developing country that accepting aid from Japan through Japan International Cooperation Agency (JICA) upon the agreement between both them. Keywords : Cooperation

Measurement invariance of the comprehensive feeding practices questionnaire in dual-earner parents with adolescent children in Chile

The Comprehensive Feeding Practices Questionnaire (CFPQ) has been evaluated in international studies, but the evaluation of its psychometric properties in Spanish, and in particular for parents of adolescents is still limited, and the invariance of measurement according to gender has not been evaluated. Therefore, the objectives of this study were: (1) To adapt the five-factor model of the CFPQ instrument to Spanish; (2) To examine the psychometric properties of this adaptation; and (3) To evaluate the measurement invariance of the model to verify the equivalence of measurement of the perceptions of food parenting practices between mothers and fathers belonging to nuclear, dual-earner families with adolescent children. Participants were 946 mothers and fathers from Southern Chile. Results showed that the conceptual equivalence for the CFPQ was achieved. An exploratory factor analysis was performed for a five-factor model: Monitoring, Child control, Restriction for weight control, Modeling and Environment. Horn’s parallel analysis identified four factors, while factor loading analysis determined the removal of the environment factor. Confirmatory factor analysis presented good reliability values. Convergent and discriminant validity was confirmed, and medium-to-high levels of goodness of fit were obtained, eliminating two items. Results supported a final model of four factors and 19 items. Multigroup analysis of the measurement model verified the configural and metric invariance between fathers and mothers, while the scalar and strict partial invariance was verified. These findings are a relevant guide to measure factorial scores in the four-factor model of the CFPQ, establishing a characterization of feeding practices of parents and adolescents.© 2023 Del Valle, Miranda, Orellana, Grunert and Schnettler. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.fi=vertaisarvioitu|en=peerReviewed

The diverging patterns of life satisfaction between families : A latent profile analysis in dual-earner parents with adolescents

This study identifies family profiles based onthe level of life satisfaction (LS) inmothers, fathers and adolescents, and variables related to their family, food, and work life.The sample was composed of 303 families of dual-earner parents (mothers’ mean age = 40.9 years, SD = 7.4, fathers’ mean age = 43.2 years, SD = 7.2) and one of their children aged between 10 and 17 years (mean age 13.3, SD = 2.4, 51.5% female). A Latent Profile Analysis (LPA) was used to identify five family profiles. Profiles differed in LS, satisfaction with family life (SWFaL), satisfaction with food-related life (SWFoL), family functioning, both parents’ worklife balance and their perception of the financial situation of the household. Balanced and imbalanced families in terms of LS differed in the three family members’ LS and SWFaL, mothers’ and children’ SWFoL and family functioning, and both parents’ perception of financial situation. These results contribute to understanding the heterogeneity of life satisfaction dynamics between and within dual-earner families.©2021 Springer Nature. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.fi=vertaisarvioitu|en=peerReviewed

Aceptación de una hortaliza con denominación de origen en dos ciudades del sur de Chile

Considering that the regional origin of foods can increase consumer acceptance, the relative importance of the designation of origin (DO) in the decision to purchase tomatoes in Temuco and Puerto Montt, Chile was evaluated, consumer segments were distinguished according to their preferences by administering a survey to 400 people. A conjoint analysis was used to determine that the variety of tomato (41.8%) was more important than DO (19.5%) and price (17.0%). Presentation and size were the least important attributes. Consumers preferred long-life tomatoes and in bunch, with Angol DO at the lowest price. A hierarchical cluster analysis distinguished three segments. The first (52.5%) was sensitive to variety. The second (13.0%) was also sensitive to variety, but they preferred to pay the highest price. The third (34.5%) was sensitive to price. All three segments preferred the tomato with Angol DO. The segments differed significantly according to gender, size of family group and level of satisfaction with their food-related life. The results indicate a good acceptance of tomatoes with Angol DO; however, particular relevance must be given to the variety of tomato produced.Considerando que la región de origen de los alimentos puede aumentar la aceptación de los consumidores, se evaluó la importancia relativa de la información referida a la denominación de origen (DO) en la decisión de compra de tomates en Temuco y Puerto Montt, Chile, y se diferenciaron segmentos de consumidores según sus preferencias, mediante una encuesta a 400 personas. Utilizando análisis conjunto se determinó que la variedad de tomate (41,8%) fue más importante que la DO (19,5%) y el precio (17,0%). La presentación y el tamaño fueron atributos poco importantes. Los consumidores prefirieron tomate larga vida y en racimo, con DO de Angol, al menor precio. Mediante análisis de conglomerados jerárquicos se diferenciaron tres segmentos. El primero (52,5%) fue sensible a la variedad. El segundo (13,0%) también fue sensible a la variedad, pero prefirieron pagar el precio más elevado. El tercero (34,5%) fue sensible al precio. Los tres segmentos prefirieron el tomate con DO de Angol. Los segmentos se diferenciaron significativamente según género, tamaño del grupo familiar y nivel de satisfacción con su alimentación. Los resultados indican buena aceptación hacia tomates con DO de Angol, sin embargo, se debe dar especial relevancia a la variedad de tomate a producir.Fil: Schnettler, Berta. Universidad de La Frontera (Chile). Facultad de Ciencias Agropecuarias y Forestales. Departamento de Producción Agropecuaria.Fil: Pihán, Rodolfo. Universidad de La Frontera (Chile). Facultad de Ciencias Agropecuarias y Forestales. Departamento de Producción Agropecuaria.Fil: Valdevenito, Ana. Universidad de La Frontera (Chile). Facultad de Ciencias Agropecuarias y Forestales. Departamento de Producción Agropecuaria.Fil: Miranda, Horacio. Universidad de La Frontera (Chile). Facultad de Ciencias Agropecuarias y Forestales. Departamento de Producción Agropecuaria.Fil: Lobos, Germán. Universidad de Talca (Chile)Fil: Grunert, Klaus G.. Universidad de Aarhus (Dinamarca

Halitosis y factores asociados en niños de 6 a 9 años de edad de la escuela Santo Domingo de la ciudad de Managua en el período comprendido de febrero a marzo del 2005

Tesis (Cirujano Dentista)--Universidad Americana, Managua, 2005Evaluar la halitosis y sus factores asociados en niños entre 6 y 9años de edad en la escuela Santo Domingo en el período comprendido de Febrero a Marzo del 2005. Identificar la prevalencia de halitosis en niños de 6 a 9 años de edad en la escuela Santo Domingo, así como también establecer el grado o nivel de halitosis en niños