495 research outputs found

    Elaboration et utilisation d'un modèle représentatif pour optimiser le soutènement des galeries minières profondes

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    The use of a same roadway to serve two workings allows to reduce the mining costs. However, at great depth, the roadways behavior become bad and their treatment have to be adapted. In-situ measurements and numerical modelling have allowed to understand the main deformation mechanisms. On this base, treatment modifications have been tested using UDEC code.L'utilisation d'une même galerie pour desservir deux chantiers d'exploitation présente des avantages économiques évidents. A forte profondeur cependant, le comportement des voies se dégrade et le soutènement habituellement mis en oeuvre n'est pas toujours bien adapté. La combinaison des mesures in situ et de la modélisation numérique a permis de déterminer les mécanismes principaux de déformation de ces voies. Sur cette base, deux modifications de leur soutènement ont été testées numériquement à l'aide du logiciel UDEC

    Physiological mechanisms and adaptation strategies of Lactuca sativa L. in response to Olea europaea L. and Ficus carica L. allelochemicals

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    Agro-industrial wastes of Ficus carica L. and Olea europaea L. represent great sources of bioactive phenolic compounds that would be actively involved in sustainable development. Most of these wastes possess a valuable source of phytotoxic compounds that would be used as potential bioherbicides, but their function and mechanisms of action in cultivated crops remain far to be understood. In this study, we investigate the biochemical and physiological mechanisms of action of fig and olive allelochemicals extracts in lettuce as a model plant for weed species studies. Results revealed that these allelochemicals triggered an oxidative stress through cell membrane damage in lettuce roots and leaves, which was mitigated by various adaptive responses. Therefore, an intricate defense system was implicated by the increase of enzymatic and non-enzymatic antioxidants in lettuce tissues. This adaptive physiological response was highly correlated with the regulation of the phenylpropanoid pathway through the distinguished activation of phenylalanine ammonia-lyase by 98% and phenolic accumulation by 85% under olive and fig leaves aqueous extracts. The outcomes of this study will help understanding the response of cultivated crop to fig and olive phenolic compounds that can be selective in their actions, or the plants can be selective in their responses

    Fascitis necrotizante de extremidad superior: a propósito de un caso

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    Los autores presentan un caso de fascitis necrotizante en miembro superior causada por la combinación de bacterias estreptococo microaerofílico y estafilococo aureus. El paciente ha sobrevivido con una pérdida orgánica mínima (amputación del quinto dedo) y una recuperación funcional completa. Se destaca el papel de la antibioterapia precoz.The authors report a case of necrotizing fascitis of the upper limb, produced by a microaerophilic streptococcus and staphilococcus aureus. The only organic sequelae for the patient was amputation of the little finger with a complete recovery of the functional capacity. The role of the early institution of high dose antibiotic therapy is emphasized

    CLIMATE CHANGE AND HUMAN ACTIVITIES IMPACT ON THE GROUNDWATER OF THE EASTERN MOROCCO: CASE OF TRIFFA PLAIN AND SHALLOW COASTAL MEDITERRANEAN AQUIFER AT SAÏDIA

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    Located at the North-eastern part of Morocco the plain of Triffa and the area of Saïdia are under a semiarid climate (Fig1). The water resources in this zone are rather fragile and influenced by a highly irregular rainfall distribution, both in time (annual and inter-annual distribution) and in space with a yearly average which does not exceed 240 mm

    Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy

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    Acknowledgments Blood biochemistry analysis and serum analysis were performed by the Easter Bush Pathology Department, University of Edinburgh. Animal husbandry was performed by Centre for Integrative Physiology bio-research restructure technical staff, University of Edinburgh. Assistance with intravenous injections was provided by Ian Coldicott (University of Sheffield) and Hannah Shorrock (University of Edinburgh). Human blood cDNA was a gift to GH from Kathy Evans, University of Edinburgh. Imaging was performed at the IMPACT imaging facility, University of Edinburgh, with technical assistance from Anisha Kubasik-Thayil. The authors would also like to thank Lyndsay Murray for technical discussions relating to qRT-PCR analysis. This work was supported by funding from the SMA Trust and the Anatomical Society (via grants to THG); the Euan MacDonald Centre for Motor Neurone Disease Research (via grants to THG and SHP); the Wellcome Trust (via grants to EJNG and THG); Muscular Dystrophy UK (via grants to THG and CGB); a Elphinstone Scholarship from the University of Aberdeen (to SHP); and The French Muscular Dystrophy Association (via grants to CM and JC).Peer reviewedPublisher PD

    Production of Sodium Bose--Einstein condensates in an optical dimple trap

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    We report on the realization of a sodium Bose--Einstein condensate (BEC) in a combined red-detuned optical dipole trap, formed by two beams crossing in a horizontal plane and a third, tightly focused dimple trap propagating vertically. We produce a BEC in three main steps: loading of the crossed dipole trap from laser-cooled atoms, an intermediate evaporative cooling stage which results in efficient loading of the auxiliary dimple trap, and a final evaporative cooling stage in the dimple trap. Our protocol is implemented in a compact setup and allows us to reach quantum degeneracy even with relatively modest initial atom numbers and available laser power

    Economic efficiency of public secondary education expenditure: how different are developed and developing countries?

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    Este estudio mide la eficiencia del gasto público en educación secundaria en 35 países desarrollados y en desarrollo mediante el uso de una metodología semiparamétrica DEA (análisis envolvente de datos) en dos pasos. En primer lugar, implementamos dos modelos de frontera transfronteriza para el período 2009-2012: uno que utiliza un aporte físico (es decir, relación maestro-alumno) y otro que utiliza un aporte monetario (es decir, gasto gubernamental por estudiante secundario). Estos resultados se corrigen por los efectos del PIB per cápita y el logro educativo de los adultos como insumos no discrecionales. Obtenemos cuatro resultados importantes: (i) los países desarrollados y en desarrollo tienen los mismos procesos de producción educativa cuando se comparan utilizando insumos físicos, pero no cuando se los compara con insumos monetarios; (ii) los países en desarrollo podrían aumentar sus tasas de matrícula y puntajes PISA en aproximadamente un 9% y un 5%, respectivamente, al mantener las mismas proporciones maestro-alumno y los niveles de gasto público que los países desarrollados; (iii) Irlanda, Japón y Corea son países eficientes en los dos modelos de frontera (Colombia también se incluye en esta categoría cuando se utiliza la relación maestro-alumno como insumo); y (iv) la sólida evidencia empírica indica que tanto el ingreso como el logro educativo de los padres afectan positivamente la eficiencia de la educación pública en ambos modelos.This study measures the efficiency of public secondary education expenditure in 35 developing and developed countries using a two-step semi-parametric DEA (data envelopment analysis) methodology. First, we implement two cross-country frontier models for the 2009-2012 period: one using a physical input (i.e., teacher-pupil ratio) and one using a monetary input (i.e., government expenditure per secondary student). These results are corrected by the effects of GDP per capita and adult educational attainment as non-discretionary inputs. We obtain four important results: (i) developed and developing countries have the same education production processes when they are compared using physical inputs but not when compared using monetary inputs; (ii) developing countries could increase their enrollment rates and PISA scores by approximately 9% and 5%, respectively, by maintaining the same teacher-pupil ratios and public spending levels as developed countries; (iii) Ireland, Japan and Korea are efficient countries in the two frontier models (Colombia is also included in this category when the teacher-pupil ratio is used as input); and (iv) robust empirical evidence indicates that both income and parental educational attainment positively affect the efficiency of public education in both models

    Seismic risk in the city of Al Hoceima (north of Morocco) using the vulnerability index method, applied in Risk-UE project

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    The final publication is available at Springer via http://dx.doi.org/10.1007/s11069-016-2566-8Al Hoceima is one of the most seismic active regions in north of Morocco. It is demonstrated by the large seismic episodes reported in seismic catalogs and research studies. However, seismic risk is relatively high due to vulnerable buildings that are either old or don’t respect seismic standards. Our aim is to present a study about seismic risk and seismic scenarios for the city of Al Hoceima. The seismic vulnerability of the existing residential buildings was evaluated using the vulnerability index method (Risk-UE). It was chosen to be adapted and applied to the Moroccan constructions for its practicality and simple methodology. A visual inspection of 1102 buildings was carried out to assess the vulnerability factors. As for seismic hazard, it was evaluated in terms of macroseismic intensity for two scenarios (a deterministic and probabilistic scenario). The maps of seismic risk are represented by direct damage on buildings, damage to population and economic cost. According to the results, the main vulnerability index of the city is equal to 0.49 and the seismic risk is estimated as Slight (main damage grade equal to 0.9 for the deterministic scenario and 0.7 for the probabilistic scenario). However, Moderate to heavy damage is expected in areas located in the newer extensions, in both the east and west of the city. Important economic losses and damage to the population are expected in these areas as well. The maps elaborated can be a potential guide to the decision making in the field of seismic risk prevention and mitigation strategies in Al Hoceima.Peer ReviewedPostprint (author's final draft
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