99 research outputs found
Seasonal variations of Saanen goat milk composition and the impact of climatic conditions
The aim of this research was to investigate the effect of climatic conditions and their impact on seasonal variations of physico-chemical characteristics of Saanen goat milk produced over a period of 4 years. Lactation period (early, mid and late) and year were considered as factors that influence physico-chemical composition of milk. Pearson's coefficient of correlation was calculated between the physico-chemical characteristics of milk (fat, proteins, lactose, non-fat dry matter, density, freezing point, pH, titrable acidity) and climatic condition parameters (air temperature, temperature humidity index-THI, solar radiation duration, relative humidity). Results showed that all physico-chemical characteristics of Saanen goat milk varied significantly throughout the lactation period and years. The decrease of fat, protein, non-fat dry matter and lactose content in goat milk during the mid-lactation period was more pronounced than was previously reported in the literature. The highest values for these characteristics were recorded in the late lactation period. Observed variations were explained by negative correlation between THI and the physico-chemical characteristics of Saanen goat milk. This indicated that Saanen goats were very prone to heat stress, which implied the decrease of physico-chemical characteristics during hot summers
Background free search for neutrinoless double beta decay with GERDA Phase II
The Standard Model of particle physics cannot explain the dominance of matter
over anti-matter in our Universe. In many model extensions this is a very
natural consequence of neutrinos being their own anti-particles (Majorana
particles) which implies that a lepton number violating radioactive decay named
neutrinoless double beta () decay should exist. The detection
of this extremely rare hypothetical process requires utmost suppression of any
kind of backgrounds.
The GERDA collaboration searches for decay of Ge
(^{76}\rm{Ge} \rightarrow\,^{76}\rm{Se} + 2e^-) by operating bare detectors
made from germanium with enriched Ge fraction in liquid argon. Here, we
report on first data of GERDA Phase II. A background level of
cts/(keVkgyr) has been achieved which is the world-best if
weighted by the narrow energy-signal region of germanium detectors. Combining
Phase I and II data we find no signal and deduce a new lower limit for the
half-life of yr at 90 % C.L. Our sensitivity of
yr is competitive with the one of experiments with
significantly larger isotope mass.
GERDA is the first experiment that will be background-free
up to its design exposure. This progress relies on a novel active veto system,
the superior germanium detector energy resolution and the improved background
recognition of our new detectors. The unique discovery potential of an
essentially background-free search for decay motivates a
larger germanium experiment with higher sensitivity.Comment: 14 pages, 9 figures, 1 table; ; data, figures and images available at
http://www.mpi-hd.mpg/gerda/publi
The first search for bosonic super-WIMPs with masses up to 1 MeV/c with GERDA
We present the first search for bosonic super-WIMPs as keV-scale dark matter
candidates performed with the GERDA experiment. GERDA is a neutrinoless
double-beta decay experiment which operates high-purity germanium detectors
enriched in Ge in an ultra-low background environment at the Laboratori
Nazionali del Gran Sasso (LNGS) of INFN in Italy. Searches were performed for
pseudoscalar and vector particles in the mass region from 60 keV/c to 1
MeV/c. No evidence for a dark matter signal was observed, and the most
stringent constraints on the couplings of super-WIMPs with masses above 120
keV/c have been set. As an example, at a mass of 150 keV/c the most
stringent direct limits on the dimensionless couplings of axion-like particles
and dark photons to electrons of and
at 90% credible interval,
respectively, were obtained.Comment: 6 pages, 3 figures, submitted to Physical Review Letters, added list
of authors, updated ref. [21
Characterization of 30 Ge enriched Broad Energy Ge detectors for GERDA Phase II
The GERmanium Detector Array (GERDA) is a low background experiment located
at the Laboratori Nazionali del Gran Sasso in Italy, which searches for
neutrinoless double beta decay of Ge into Se+2e. GERDA has
been conceived in two phases. Phase II, which started in December 2015,
features several novelties including 30 new Ge detectors. These were
manufactured according to the Broad Energy Germanium (BEGe) detector design
that has a better background discrimination capability and energy resolution
compared to formerly widely-used types. Prior to their installation, the new
BEGe detectors were mounted in vacuum cryostats and characterized in detail in
the HADES underground laboratory in Belgium. This paper describes the
properties and the overall performance of these detectors during operation in
vacuum. The characterization campaign provided not only direct input for GERDA
Phase II data collection and analyses, but also allowed to study detector
phenomena, detector correlations as well as to test the strength of pulse shape
simulation codes.Comment: 29 pages, 18 figure
Limit on the Radiative Neutrinoless Double Electron Capture of Ar from GERDA Phase I
Neutrinoless double electron capture is a process that, if detected, would
give evidence of lepton number violation and the Majorana nature of neutrinos.
A search for neutrinoless double electron capture of Ar has been
performed with germanium detectors installed in liquid argon using data from
Phase I of the GERmanium Detector Array (GERDA) experiment at the Gran Sasso
Laboratory of INFN, Italy. No signal was observed and an experimental lower
limit on the half-life of the radiative neutrinoless double electron capture of
Ar was established: 3.6 10 yr at 90 % C.I.Comment: 7 pages, 3 figure
The Large Enriched Germanium Experiment for Neutrinoless Double Beta Decay (LEGEND)
The observation of neutrinoless double-beta decay (0)
would show that lepton number is violated, reveal that neutrinos are Majorana
particles, and provide information on neutrino mass. A discovery-capable
experiment covering the inverted ordering region, with effective Majorana
neutrino masses of 15 - 50 meV, will require a tonne-scale experiment with
excellent energy resolution and extremely low backgrounds, at the level of
0.1 count /(FWHMtyr) in the region of the signal. The
current generation Ge experiments GERDA and the MAJORANA DEMONSTRATOR
utilizing high purity Germanium detectors with an intrinsic energy resolution
of 0.12%, have achieved the lowest backgrounds by over an order of magnitude in
the 0 signal region of all 0
experiments. Building on this success, the LEGEND collaboration has been formed
to pursue a tonne-scale Ge experiment. The collaboration aims to develop
a phased 0 experimental program with discovery potential
at a half-life approaching or at years, using existing resources as
appropriate to expedite physics results.Comment: Proceedings of the MEDEX'17 meeting (Prague, May 29 - June 2, 2017
Pulse shape analysis in Gerda Phase II
The GERmanium Detector Array (Gerda) collaboration searched for neutrinoless double- decay in Ge using isotopically enriched high purity germanium detectors at the Laboratori Nazionali del Gran Sasso of INFN. After Phase I (2011–2013), the experiment benefited from several upgrades, including an additional active veto based on LAr instrumentation and a significant increase of mass by point-contact germanium detectors that improved the half-life sensitivity of Phase II (2015–2019) by an order of magnitude. At the core of the background mitigation strategy, the analysis of the time profile of individual pulses provides a powerful topological discrimination of signal-like and background-like events. Data from regular Th calibrations and physics data were both considered in the evaluation of the pulse shape discrimination performance. In this work, we describe the various methods applied to the data collected in Gerda Phase II corresponding to an exposure of 103.7 kg year. These methods suppress the background by a factor of about 5 in the region of interest around keV, while preserving % of the signal. In addition, an exhaustive list of parameters is provided which were used in the final data analysis
Losartan Improved Antioxidant Defense, Renal Function and Structure of Postischemic Hypertensive Kidney
Ischemic acute renal failure (ARF) is a highly complex disorder involving renal vasoconstriction, filtration failure, tubular obstruction, tubular backleak and generation of reactive oxygen species. Due to this complexity, the aim of our study was to explore effects of Angiotensin II type 1 receptor (AT1R) blockade on kidney structure and function, as well as oxidative stress in spontaneously hypertensive rats (SHR) after renal ischemia reperfusion injury. Experiments were performed on anaesthetized adult male SHR in the model of ARF with 40 minutes clamping the left renal artery. The right kidney was removed and 40 minutes renal ischemia was performed. Experimental groups received AT1R antagonist (Losartan) or vehicle (saline) in the femoral vein 5 minutes before, during and 175 minutes after the period of ischemia. Biochemical parameters were measured and kidney specimens were collected 24h after reperfusion. ARF significantly decreased creatinine and urea clearance, increased LDL and lipid peroxidation in plasma. Treatment with losartan induced a significant increase of creatinine and urea clearance, as well as HDL. Lipid peroxidation in plasma was decreased and catalase enzyme activity in erythrocytes was increased after losartan treatment. Losartan reduced cortico-medullary necrosis and tubular dilatation in the kidney. High expression of pro-apoptotic Bax protein in the injured kidney was downregulated after losartan treatment. Our results reveal that angiotensin II (via AT1R) mediates the most postischemic injuries in hypertensive kidney through oxidative stress enhancement. Therefore, blockade of AT1R may have beneficial effects in hypertensive patients who have developed ARF
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