Sustainable Delivery of Speech-Language Therapy Services in Small Island Developing States Using Information and Communication Technology – A Study of the Maldives

Small Island Developing States (SIDS), a subgroup of Majority world countries, face complex challenges providing equitable access to speech-language therapy (SLT) services. Increasing use of information and communication technology (ICT) to enhance SLT services is seen in the Minority world. This study explored the potential of using ICT to provide sustainable SLT services in one SIDS, the Maldives. A mixed method approach was used integrating data from (a) 21 online documents, (b) interview with an ICT official, and (c) surveys of 13 island councillors and 73 parents of children with communication difficulties. Almost 100% of the population had access to mobile phones and mobile broadband internet. Most parents were active and frequent ICT users. The government provided financial aid for people with disabilities which could be utilised to access ICT for services. Asynchronous service delivery using accessible ICT and parents as agents of service delivery can potentially enhance SLT services

The BASES expert statement in safeguarding in the sport sciences.

Within the context of sport and exercise science, safeguarding concerns a professional obligation to protect all parties (for example the client, athlete and/or self) from maltreatment or harm (Mountjoy et al., 2016). Safeguarding should embrace relational (others), individual (self) and organisational (culture) considerations. The understanding of physical, emotional and social well-being and freedom from discrimination are the focus of safeguarding education. In this expert statement we provide information in three key areas: 1) a brief summary of the research themes and findings surrounding maltreatment in sport; 2) a discussion of safeguarding within the sport and exercise profession and finally; 3) recommendations for sport and exercise scientists on matters of safeguarding

Improving corporate governance in state-owned corporations in China: which way forward?

This article discusses corporate governance in China. It outlines the basic agency problem in Chinese listed companies and questions the effectiveness of the current mechanisms employed to improve their standards of governance. Importantly, it considers alternative means through which corporate practice in China can be brought into line with international expectations and stresses the urgency with which this task must be tackled. It concludes that regulators in China must construct a corporate governance model which is compatible with its domestic setting and not rush to adopt governance initiatives modelled on those in cultures which are fundamentally different in the hope of also reproducing their success

Double quick, double click reversible peptide “stapling”

The development of constrained peptides for inhibition of protein–protein interactions is an emerging strategy in chemical biology and drug discovery. This manuscript introduces a versatile, rapid and reversible approach to constrain peptides in a bioactive helical conformation using BID and RNase S peptides as models. Dibromomaleimide is used to constrain BID and RNase S peptide sequence variants bearing cysteine (Cys) or homocysteine (hCys) amino acids spaced at i and i + 4 positions by double substitution. The constraint can be readily removed by displacement of the maleimide using excess thiol. This new constraining methodology results in enhanced α-helical conformation (BID and RNase S peptide) as demonstrated by circular dichroism and molecular dynamics simulations, resistance to proteolysis (BID) as demonstrated by trypsin proteolysis experiments and retained or enhanced potency of inhibition for Bcl-2 family protein–protein interactions (BID), or greater capability to restore the hydrolytic activity of the RNAse S protein (RNase S peptide). Finally, use of a dibromomaleimide functionalized with an alkyne permits further divergent functionalization through alkyne–azide cycloaddition chemistry on the constrained peptide with fluorescein, oligoethylene glycol or biotin groups to facilitate biophysical and cellular analyses. Hence this methodology may extend the scope and accessibility of peptide stapling

Tidal Stream vs. Wind Energy: The Value of Cyclic Power When Combined with Short-Term Storage in Hybrid Systems

This study quantifies the technical, economic and environmental performance of hybrid systems that use either a tidal stream or wind turbine, alongside short-term battery storage and back-up oil generators. The systems are designed to partially displace oil generators on the island of Alderney, located in the British Channel Islands. The tidal stream turbine provides four power generation periods per day, every day. This relatively high frequency power cycling limits the use of the oil generators to 1.6 GWh/year. In contrast, low wind resource periods can last for days, forcing the wind hybrid system to rely on the back-up oil generators over long periods, totalling 2.4 GWh/year (50% higher). For this reason the tidal hybrid system spends £0.25 million/year less on fuel by displacing a greater volume of oil, or £6.4 million over a 25 year operating life, assuming a flat cost of oil over this period. The tidal and wind hybrid systems achieve an oil displacement of 78% and 67% respectively (the same as the reduction in carbon emissions). For the wind hybrid system to displace the same amount of oil as the tidal hybrid system, two additional wind turbines are needed. The ability of the battery to store excess turbine energy during high tidal/wind resource periods relies on opportunities to regularly discharge stored energy. The tidal hybrid system achieves this during slack tides. Periods of high wind resource outlast those of high tidal resource, causing the battery to often remain fully charged and excess wind power to be curtailed. Consequently the wind hybrid system curtails 1.9 GWh/year, whilst the tidal turbine curtails 0.2 GWh/year. The ability of the tidal stream turbines to reduce curtailment, fuel costs and carbon emissions may provide a case for implementing them in hybrid systems, if these benefits outweigh their relatively high capital and operating expenditure.</jats:p

The role of mothers-in-law in antenatal care decision-making in Nepal: a qualitative study

Background Antenatal care (ANC) has been recognised as a way to improve health outcomes for pregnant women and their babies. However, only 29% of pregnant women receive the recommended four antenatal visits in Nepal but reasons for such low utilisation are poorly understood. As in many countries of South Asia, mothers-in-law play a crucial role in the decisions around accessing health care facilities and providers. This paper aims to explore the mother-in-law’s role in (a) her daughter-in-law’s ANC uptake; and (b) the decision-making process about using ANC services in Nepal. Methods In-depth interviews were conducted with 30 purposively selected antenatal or postnatal mothers (half users, half non-users of ANC), 10 husbands and 10 mothers-in-law in two different (urban and rural) communities. Results Our findings suggest that mothers-in-law sometime have a positive influence, for example when encouraging women to seek ANC, but more often it is negative. Like many rural women of their generation, all mothers-in-law in this study were illiterate and most had not used ANC themselves. The main factors leading mothers-in-law not to support/ encourage ANC check ups were expectations regarding pregnant women fulfilling their household duties, perceptions that ANC was not beneficial based largely on their own past experiences, the scarcity of resources under their control and power relations between mothers-in-law and daughters-in-law. Individual knowledge and social class of the mothers-in-law of users and non-users differed significantly, which is likely to have had an effect on their perceptions of the benefits of ANC. Conclusion Mothers-in-law have a strong influence on the uptake of ANC in Nepal. Understanding their role is important if we are to design and target effective community-based health promotion interventions. Health promotion and educational interventions to improve the use of ANC should target women, husbands and family members, particularly mothers-in-law where they control access to family resources

Living for the weekend: youth identities in northeast England

Consumption and consumerism are now accepted as key contexts for the construction of youth identities in de-industrialized Britain. This article uses empirical evidence from interviews with young people to suggest that claims of `new community' are overstated, traditional forms of friendship are receding, and increasingly atomized and instrumental youth identities are now being culturally constituted and reproduced by the pressures and anxieties created by enforced adaptation to consumer capitalism. Analysis of the data opens up the possibility of a critical rather than a celebratory exploration of the wider theoretical implications of this process