469 research outputs found

    Evaluating Department Chair and Student Leadership in Higher Education

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    In higher education, assessment of leadership capacities and performance of department chairs and students allows stakeholders to evaluate individuals and programs

    Evaluating department chairs’ effectiveness using faculty ratings

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    Doctor of PhilosophyCurriculum and Instruction ProgramsStephen L. BentonThis study examined relationships between faculty perceptions of their academic department chair’s overall effectiveness and their ratings of his/her personal characteristics and administrative methods. The experimenter analyzed secondary data obtained from the Individual Development and Educational Assessment (IDEA) Center’s Feedback for Department Chairs system. Data came from 604 department chairs and their corresponding 9,125 faculty members across the years 2003 to 2007. Faculty completed the 70-item Faculty Perceptions of Department Head/Chair Survey, and their department chair responded to the 30-item Department Head/Chair Information Form. Exploratory factor analysis (EFA) of department chair ratings revealed three underlying dimensions of administrative responsibilities, ranked in order of importance: Departmental Operations, Faculty Enhancement, and Research and Assessment. EFAs of faculty ratings determined one factor explained the department chair’s personal characteristics—Flexibility/Adaptability—and one factor explained the department chair’s performance of administrative methods—Communication and Coordination. Items with high component matrix coefficients were summed to produce scales with high reliability for each factor. Multiple regression analysis indicated that faculty ratings of the department chair’s Flexibility/Adaptability and Communication and Coordination explained 83% of the variance in their ratings of the department chair’s overall effectiveness (p < .001). Ratings on Communication and Coordination explained the most variance. Faculty ratings of the department chair’s performance of administrative responsibilities also explained 83% of the variance in their ratings of the chair’s overall effectiveness (p < .001). Faculty Enhancement showed the strongest relationship. The findings help to explain the underlying dimensions of the academic department chair’s effectiveness and the role of faculty ratings in evaluation

    USAID Feed the Future Innovation Lab: Global research in sustainable intensification

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    United States Agency for International Developmen

    Mobilisation and remobilisation of a large archetypal pathogenicity island of uropathogenic Escherichia coli in vitro support the role of conjugation for horizontal transfer of genomic islands

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    Background: A substantial amount of data has been accumulated supporting the important role of genomic islands (GEIs) - including pathogenicity islands (PAIs) - in bacterial genome plasticity and the evolution of bacterial pathogens. Their instability and the high level sequence similarity of different (partial) islands suggest an exchange of PAIs between strains of the same or even different bacterial species by horizontal gene transfer (HGT). Transfer events of archetypal large genomic islands of enterobacteria which often lack genes required for mobilisation or transfer have been rarely investigated so far. Results: To study mobilisation of such large genomic regions in prototypic uropathogenic E. coli (UPEC) strain 536, PAI II536 was supplemented with the mobRP4 region, an origin of replication (oriVR6K), an origin of transfer (oriTRP4) and a chloramphenicol resistance selection marker. In the presence of helper plasmid RP4, conjugative transfer of the 107-kb PAI II536 construct occured from strain 536 into an E. coli K-12 recipient. In transconjugants, PAI II536 existed either as a cytoplasmic circular intermediate (CI) or integrated site-specifically into the recipient’s chromosome at the leuX tRNA gene. This locus is the chromosomal integration site of PAI II536 in UPEC strain 536. From the E. coli K-12 recipient, the chromosomal PAI II536 construct as well as the CIs could be successfully remobilised and inserted into leuX in a PAI II536 deletion mutant of E. coli 536. Conclusions: Our results corroborate that mobilisation and conjugal transfer may contribute to evolution of bacterial pathogens through horizontal transfer of large chromosomal regions such as PAIs. Stabilisation of these mobile genetic elements in the bacterial chromosome result from selective loss of mobilisation and transfer functions of genomic islands

    Population based Ant Colony Optmization on FPGA

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    We propose to modify a type of ant algorithm called Population based Ant Colony Optimization (P-ACO) to allow implementation on an FPGA architecture. Ant algorithms are adapted from the natural behavior of ants and used to find good solutions to combinatorial optimization problems. General layout on the FPGA and algorithmic description are covered. The most notable achievements featured in this paper are a runtime reduction and including the approximation of the heuristic function by a small set of favored decisions which changes over time

    Propiedades puzolánicas de desechos de la industria azucarera (primera parte)

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    Non altered straw and sugar cane bagasse ash (CPC, CBC) collected directly from the boilers in the sugar industry and from non-controlled burning in the open fields turned up to be a reasonably good pozzolana, which can be utilized for the manufacture of lime-pozzolana binders. This paper presents a detailed survey of this material with the aim to use it as raw material in the manufacture of binders.Las cenizas de bagazo y paja de caña de azúcar (CPC, CBC), obtenidas en forma inalterada directamente de las calderas de la fábrica de azúcar, y de la quema incontrolada en el campo, representan una interesante fuente de puzolana reactiva, con potencialidad de ser usada en la preparación de aglomerantes del tipo cal/puzolana. El trabajo que se presenta realizó una evaluación integral de estas puzolanas, con el interés de utilizarlas como materia prima en la producción de aglomerantes

    Propiedades puzolánicas de desechos de la industria azucarera (segunda parte)

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    Results of studies conducted in lime pozzolana pastes are introduced in this paper. The pozzolana was sourced from Sugar Cane Baggasse Ash (CBC) and Sugar Cane Straw Ash (CPC). The hydration of this binder was carefully monitored by means of instrumental techniques with the aim of describing the kinetics of the reaction.Se presentan los resultados de estudios realizados en pastas fabricadas con un aglomerante del tipo calpuzolana, utilizando cenizas de paja de caña (CPC) y cenizas de bagazo de caña (CBC) como puzolanas. Se muestran los estudios que caracterizan la reacción de hidratación desarrollada en este tipo de aglomerante. La evaluación realizada, utilizando diferentes técnicas instrumentales, permitieron estudiar y comprender la cinética de la reacción

    Network Archaeology: Uncovering Ancient Networks from Present-day Interactions

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    Often questions arise about old or extinct networks. What proteins interacted in a long-extinct ancestor species of yeast? Who were the central players in the Last.fm social network 3 years ago? Our ability to answer such questions has been limited by the unavailability of past versions of networks. To overcome these limitations, we propose several algorithms for reconstructing a network's history of growth given only the network as it exists today and a generative model by which the network is believed to have evolved. Our likelihood-based method finds a probable previous state of the network by reversing the forward growth model. This approach retains node identities so that the history of individual nodes can be tracked. We apply these algorithms to uncover older, non-extant biological and social networks believed to have grown via several models, including duplication-mutation with complementarity, forest fire, and preferential attachment. Through experiments on both synthetic and real-world data, we find that our algorithms can estimate node arrival times, identify anchor nodes from which new nodes copy links, and can reveal significant features of networks that have long since disappeared.Comment: 16 pages, 10 figure

    Stability, Entrapment and Variant Formation of Salmonella Genomic Island 1

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    <div><h3>Background</h3><p>The <em>Salmonella</em> genomic island 1 (SGI1) is a 42.4 kb integrative mobilizable element containing several antibiotic resistance determinants embedded in a complex integron segment In104. The numerous SGI1 variants identified so far, differ mainly in this segment and the explanations of their emergence were mostly based on comparative structure analyses. Here we provide experimental studies on the stability, entrapment and variant formation of this peculiar gene cluster originally found in <em>S</em>. Typhimurium.</p> <h3>Methodology/Principal Findings</h3><p>Segregation and conjugation tests and various molecular techniques were used to detect the emerging SGI1 variants in <em>Salmonella</em> populations of 17 <em>Salmonella enterica</em> serovar Typhimurium DT104 isolates from Hungary. The SGI1s in these isolates proved to be fully competent in excision, conjugal transfer by the IncA/C helper plasmid R55, and integration into the <em>E. coli</em> chromosome. A trap vector has been constructed and successfully applied to capture the island on a plasmid. Monitoring of segregation of SGI1 indicated high stability of the island. SGI1-free segregants did not accumulate during long-term propagation, but several SGI1 variants could be obtained. Most of them appeared to be identical to SGI1-B and SGI1-C, but two new variants caused by deletions via a short-homology-dependent recombination process have also been detected. We have also noticed that the presence of the conjugation helper plasmid increased the formation of these deletion variants considerably.</p> <h3>Conclusions/Significance</h3><p>Despite that excision of SGI1 from the chromosome was proven in SGI1<sup>+</sup><em>Salmonella</em> populations, its complete loss could not be observed. On the other hand, we demonstrated that several variants, among them two newly identified ones, arose with detectable frequencies in these populations in a short timescale and their formation was promoted by the helper plasmid. This reflects that IncA/C helper plasmids are not only involved in the horizontal spreading of SGI1, but may also contribute to its evolution.</p> </div
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