37 research outputs found
Children’s and adults’ understanding of death: Cognitive, parental, and experiential influences
This study explored the development of understanding of death in a sample of 4- to 11-year-old British children and adults (N = 136). It also investigated four sets of possible influences on this development: parents’ religion and spiritual beliefs, cognitive ability, socioeconomic status, and experience of illness and death. Participants were interviewed using the “death concept” interview that explores understanding of the subcomponents of inevitability, universality, irreversibility, cessation, and causality of death. Children understood key aspects of death from as early as 4 or 5 years, and with age their explanations of inevitability, universality, and causality became increasingly biological. Understanding of irreversibility and the cessation of mental and physical processes also emerged during early childhood, but by 10 years many children’s explanations reflected not an improved biological understanding but rather the coexistence of apparently contradictory biological and supernatural ideas—religious, spiritual, or metaphysical. Evidence for these coexistent beliefs was more prevalent in older children than in younger children and was associated with their parents’ religious and spiritual beliefs. Socioeconomic status was partly related to children’s biological ideas, whereas cognitive ability and experience of illness and death played less important roles. There was no evidence for coexistent thinking among adults, only a clear distinction between biological explanations about death and supernatural explanations about the afterlife
Morphine drug discrimination testing and substitution assessments in adult male Sprague–Dawley rats
Short and Long-Term Delayed Reassessment of Drug Discrimination Testing in Adult Female SD Rats
The THC Tetrad Test: Characterization, Evaluation, and Screening of WIN55 212-2 and Other Test Substances in Wistar Han Rats
Morphine Drug Discrimination Testing and Substitution Assessments in Adult Male Sprague–Dawley Rats
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Perspective: Challenges and Future Directions in Clinical Research with Nuts and Berries.
Consumption of nuts and berries are considered part of a healthy eating pattern. Nuts and berries contain a complex nutrient profile consisting of essential vitamins and minerals, fiber, polyunsaturated fatty acids, and phenolics in quantities that improve physiological outcomes. The spectrum of health outcomes that may be impacted by the consumptions of nuts and berries includes cardiovascular, gut microbiome, and cognitive, among others. Recently, new insights regarding the bioactive compounds found in both nuts and berries have reinforced their role for use in precision nutrition efforts. However, challenges exist that can affect the generalizability of outcomes from clinical studies, including inconsistency in study designs, homogeneity of test populations, variability in test products and control foods, and assessing realistic portion sizes. Future research centered on precision nutrition and multi-omics technologies will yield new insights. These and other topics such as funding streams and perceived risk-of-bias were explored at an international nutrition conference focused on the role of nuts and berries in clinical nutrition. Successes, challenges, and future directions with these foods are presented here