859 research outputs found

    Burton V. Barnes as a forest botanist

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/120432/1/Dick2016_Barnes_Tribute.pdfDescription of Dick2016_Barnes_Tribute.pdf : Main articl

    A bilingual advantage in controlling language interference during sentence comprehension

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    This study compared the comprehension of syntactically simple with more complex sentences in Italian–English adult bilinguals and monolingual controls in the presence or absence of sentence-level interference. The task was to identify the agent of the sentence and we primarily examined the accuracy of response. The target sentence was signalled by the gender of the speaker, either a male or a female, and this varied over trials, where the target was spoken in a male voice the distractor was spoken in a female voice and vice versa. In contrast to other work showing a bilingual disadvantage in sentence comprehension under conditions of noise, we show that in this task, where voice permits selection of the target, adult bilingual speakers are in fact better able than their monolingual Italian peers to resist sentence-level interference when comprehension demands are high. Within bilingual speakers we also found that degree of proficiency in English correlated with the ability to resist interference for complex sentences both when the target and distractor were in Italian and when the target was in English and the distractor in Italian

    Adalimumab in Juvenile Idiopathic Arthritis–Associated Uveitis:5-Year Follow-up of the Bristol Participants of the SYCAMORE Trial

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    PURPOSE:To determine longer-term outcomes of participants enrolled from a single center in the SYCAMORE trial, a randomized placebo-controlled trial of adalimumab versus placebo in children with juvenile idiopathic arthritis-associated uveitis (JIA-U) uncontrolled on methotrexate. DESIGN:Retrospective interventional case series. METHODS:Medical records of all 28 SYCAMORE participants recruited at the Bristol Eye Hospital were reviewed at approximately 3-monthly intervals up to 5 years from the trial randomization date. Uveitis activity, treatment course, visual outcomes, ocular complications and adverse events were recorded. Data are presented using summary statistics. RESULTS:Following withdrawal of the investigational medicinal product (IMP), 25 of the 28 participants were started on adalimumab for active juvenile idiopathic arthritis-associated uveitis (JIA-U). Of the 12 participants in the active treatment arm of the SYCAMORE study, 11 (92%) were restarted on adalimumab after withdrawal of the IMP for active JIA-U (median time to flare 188 days (range 42-413)). Two participants stopped adalimumab for uncontrolled JIA-U. One participant had a reduction in vision to 0.3 due to cataract. Mean visual acuity for the remaining 27 participants was -0.04 (right eye) and -0.05 (left eye). CONCLUSIONS:Drug-induced remission of JIA-U did not persist when adalimumab was withdrawn after 1-2 years treatment. Adalimumab was well tolerated and visual acuity outcomes were excellent

    HgCdTe Avalanche Photodiode Array Detectors with Single Photon Sensitivity and Integrated Detector Cooler Assemblies for Space Lidar Applications

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    A HgCdTe avalanche photodiode (APD) focal plane array assembly with linear mode photon-counting capability has been developed for space lidar applications. An integrated detector cooler assembly (IDCA) has been built using a miniature Stirling cooler. A microlens array has been included to improve the fill factor. The HgCdTe APD has a spectral response from 0.9- to 4.3-m wavelengths, a photon detection efficiency as high as 70%, and a dark count rate of <250 kHz at 110 K. The mass of the IDCA is 0.8 kg and the total electrical power consumption is about 7 W. The HgCdTe APD arrays have been characterized at NASA Goddard Space Flight Center. A series of environmental tests have been conducted for the IDCAs, including vibration, thermal cycling, and thermal vacuum tests. A description of the device and the test results at NASA are given in this paper

    Surface Charge Control of Quantum Dot Blinking

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    A characteristic property of colloidal semiconductor nanocrystal quantum dots (QDs) is their emission intermittency. Although a unifying theory of QD photoprocesses remains elusive, the importance of charged states is clear. We now report a new approach to directly study the role of surface charge on QD emission by adding metal ions to individual, core-only QDs immobilized in aqueous solution in an agarose gel. The CdTe QDs show very stable emission in the absence of metal ions but a dramatic and reversible increase in blinking due to the presence of trivalent metal ions. Our results support a charge-separation model, in which the major blinking pathway is the surface trapping of electrons; transiently bound metal ions close to the QD surface enhance this process

    Polymorphic Microsatellite Loci for Virola sebifera (Myristicaceae) Derived from Shotgun 454 Pyrosequencing

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    This work is licensed under a Creative Commons Attribution License (CC-BY-NC-SA) (http://creativecommons.org/licenses/by-nc-sa/4.0/)Premise of the study: Polymorphic microsatellite loci were characterized in the dioecious neotropical rainforest tree Virola sebifera. The markers will be used to study ecological and genetic impacts of hunting and landscape change in this vertebrate-dispersed, insect-pollinated tree species. Methods and Results: Simple sequence repeat (SSR) markers were screened from genomic libraries of South American V. sebifera obtained by shotgun 454 pyrosequencing. Primer pairs were tested on Panamanian samples (N = 42). Approximately 52% of the 61 tested SSR markers amplified, and 16% were polymorphic. Ten selected polymorphic SSR loci contained seven to 15 alleles per locus, and polymorphic information content averaged 0.694. Observed heterozygosity ranged from 0.465 to 0.905, and expected heterozygosity was between 0.477 and 0.876. Conclusions: The 10 polymorphic loci will be useful in studying gene flow and genetic structure at local and regional spatial scales in V. sebifera

    Racial and ethnic disparities in access to minimally invasive mitral valve surgery

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    IMPORTANCE: Whether people from racial and ethnic minority groups experience disparities in access to minimally invasive mitral valve surgery (MIMVS) is not known. OBJECTIVE: To investigate racial and ethnic disparities in the utilization of MIMVS. DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used data from the Society of Thoracic Surgeons Database for patients who underwent mitral valve surgery between 2014 and 2019. Statistical analysis was performed from January 24 to August 11, 2022. EXPOSURES: Patients were categorized as non-Hispanic White, non-Hispanic Black, and Hispanic individuals. MAIN OUTCOMES AND MEASURES: The association between MIMVS (vs full sternotomy) and race and ethnicity were evaluated using logistic regression. RESULTS: Among the 103 753 patients undergoing mitral valve surgery (mean [SD] age, 62 [13] years; 47 886 female individuals [46.2%]), 10 404 (10.0%) were non-Hispanic Black individuals, 89 013 (85.8%) were non-Hispanic White individuals, and 4336 (4.2%) were Hispanic individuals. Non-Hispanic Black individuals were more likely to have Medicaid insurance (odds ratio [OR], 2.21; 95% CI, 1.64-2.98; P \u3c .001) and to receive care from a low-volume surgeon (OR, 4.45; 95% CI, 4.01-4.93; P \u3c .001) compared with non-Hispanic White individuals. Non-Hispanic Black individuals were less likely to undergo MIMVS (OR, 0.65; 95% CI, 0.58-0.73; P \u3c .001), whereas Hispanic individuals were not less likely to undergo MIMVS compared with non-Hispanic White individuals (OR, 1.08; 95% CI, 0.67-1.75; P = .74). Patients with commercial insurance had 2.35-fold higher odds of undergoing MIMVS (OR, 2.35; 95% CI, 2.06-2.68; P \u3c .001) than those with Medicaid insurance. Patients operated by very-high volume surgeons (300 or more cases) had 20.7-fold higher odds (OR, 20.70; 95% CI, 12.7-33.9; P \u3c .001) of undergoing MIMVS compared with patients treated by low-volume surgeons (less than 20 cases). After adjusting for patient risk, non-Hispanic Black individuals were still less likely to undergo MIMVS (adjusted OR [aOR], 0.88; 95% CI, 0.78-0.99; P = .04) and were more likely to die or experience a major complication (aOR, 1.25; 95% CI, 1.16-1.35; P \u3c .001) compared with non-Hispanic White individuals. CONCLUSIONS AND RELEVANCE: In this cross-sectional study, non-Hispanic Black patients were less likely to undergo MIMVS and more likely to die or experience a major complication than non-Hispanic White patients. These findings suggest that efforts to reduce inequity in cardiovascular medicine may need to include increasing access to private insurance and high-volume surgeons

    Role of melt supply in oceanic detachment faulting and formation of megamullions

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    Author Posting. © Geological Society of America, 2008. This article is posted here by permission of Geological Society of America for personal use, not for redistribution. The definitive version was published in Geology 36 (2008): 455-458, doi:10.1130/G24639A.1.Normal faults are ubiquitous on mid-ocean ridges and are expected to develop increasing offset with reduced spreading rate as the proportion of tectonic extension increases. Numerous long-lived detachment faults that form megamullions with large-scale corrugations have been identified on magma-poor mid-ocean ridges, but recent studies suggest, counterintuitively, that they may be associated with elevated magmatism. We present numerical models and geological data to show that these detachments occur when ~30%–50% of total extension is accommodated by magmatic accretion and that there is significant magmatic accretion in the fault footwalls. Under these low-melt conditions, magmatism may focus unevenly along the spreading axis to create an irregular brittle-plastic transition where detachments root, thus explaining the origin of the enigmatic corrugations. Morphological and compositional characteristics of the oceanic lithosphere suggested by this study provide important new constraints to assess the distribution of magmatic versus tectonic extension along mid-ocean ridges.This research was supported by the National Science Foundation and by the Henry Bryant Bigelow Chair in Oceanography to Tucholke at Woods Hole Oceanographic Institution
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