94 research outputs found

    The Four-Year College Pipeline and Factors Related to Bachelor\u27s Degree Completion for High School Graduates

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    This study examines students\u27 progress from high school graduation through college enrollment and completion. Much of the existing research frames high school dropout, college access, and college completion as separate phenomena; few studies examine individuals\u27 transitions across these points. Thinking about these events as related pieces of a pathway to educational attainment is called an education pipeline perspective. This perspective is particularly useful today, given recent reforms aimed at improving high school academic achievement, preparing students for college and careers, and increasing educational attainment. Using two nationally representative, longitudinal data sets (ELS:2002 and NELS:88) I examined changes in the education pipeline for high school seniors in the 2004 and 1992 cohorts. I also explored the relationship between bachelor\u27s degree completion and high school academic achievement using logistic regression for students from the 2004 senior cohort who enrolled on-time in four-year institutions. The logistic regression results were used to conduct a path analysis modeling to what extent the experience of transferring from a four-year college mediates the relationship between bachelor\u27s degree completion and academic achievement. Findings from this study indicate that a greater percentage of the 2004 cohort enrolled in college compared to the previous cohort, but the increase was largely driven by students who delayed enrollment by six months or more. The six-year bachelor\u27s degree completion rate of the 2004 cohort was also lower than that of the 1992 cohort. Additionally, students who transferred from four-year institutions tended to switch to public two-year institutions. Results from the regression analyses suggest that high school GPA was a stronger predictor of bachelor\u27s completion than SAT score; however, SAT score better predicted transferring. Transferring was a significant, but weak mediator of the relationship between academic achievement and bachelor\u27s degree completion. This study\u27s findings contribute to the understanding of student transitions along the education pipeline and to the literature on academic achievement, transfer, and bachelor\u27s degree completion

    Evaluation of the i3 Scale-up of Reading Recovery | Year One Report, 2011-12

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    Reading Recovery (RR) is a short-term early intervention designed to help the lowest-achieving readers in first grade reach average levels of classroom performance in literacy. Students identified to receive Reading Recovery meet individually with a specially trained Reading Recovery (RR) teacher every school day for 30-minute lessons over a period of 12 to 20 weeks. The purpose of these lessons is to support rapid acceleration of each child's literacy learning. In 2010, The Ohio State University received a Scaling Up What Works grant from the U.S. Department of Education's Investing in Innovation (i3) Fund to expand the use of Reading Recovery across the country. The award was intended to fund the scale-up of Reading Recovery by training 3,675 new RR Teachers in U.S. schools, thereby expanding capacity to allow service to an additional 88,200 students.The Consortium for Policy Research in Education (CPRE) was contracted to conduct an independent evaluation of the i3 scale up of Reading Recovery over the course of five years. The evaluation includes parallel rigorous experimental and quasi-experimental designs for estimating program impacts, coupled with a large-scale mixed-methods study of program implementation under the i3 scale-up. This report presents findings through the second year of the evaluation. The primary goals of this evaluation were: a) to assess the success of the scale-up in meeting the i3 grant's expansion goals; b) to document the implementation of scale-up and fidelity to program standards; and, c) to provide experimental evidence of the impacts of Reading Recovery on student learning under this scale-up effort

    Evaluation of the i3 Scale-Up of Reading Recovery | Year Two Report, 2012-13

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    Reading Recovery is a short-term early intervention designed to help the lowest-achieving readers in first grade reach average levels of classroom performance in literacy. Students identified to receive Reading Recovery meet individually with a specially trained Reading Recovery teacher every school day for 30-minute lessons over a period of 12 to 20 weeks. The purpose of these lessons is to support rapid acceleration of each child’s literacy learning. In 2010, The Ohio State University received a Scaling Up What Works grant from the U.S. Department of Education Investing in Innovation (i3) Fund to expand the use of Reading Recovery across the country. The award was intended to fund the training of 3,675 new Reading Recovery teachers in U.S. schools, thereby expanding service to an additional 88,200 students. The Consortium for Policy Research in Education (CPRE) was contracted to conduct an independent evaluation of the i3 scale-up of Reading Recovery over the course of five years. The evaluation includes parallel rigorous experimental and quasi-experimental designs for estimating program impacts, coupled with a large-scale mixed-methods study of program implementation. This report presents the findings of the second year of the evaluation. The primary goals of this evaluation are: a) to provide experimental evidence of the impacts of Reading Recovery on student learning under this scale-up effort ; b) to assess the success of the scale-up in meeting the i3 grant’s expansion goals; and c) to document the implementation of the scale-up and fidelity to program standards. This document is the second in a series of three reports based on our external evaluation of the Reading Recovery i3 Scale-Up. This report presents results from the impact and implementation studies conducted over the 2012-2013 school year—the third year of the scale-up effort and the second full year of the evaluation. In order to estimate the impacts of the program, a sample of first graders who had been selected to receive Reading Recovery were randomly assigned to a treatment group that received Reading Recovery immediately, or to a control group that did not receive Reading Recovery until the treatment group had exited the intervention. The reading achievement of students in this sample was assessed using a standardized assessment of reading achievement—the Iowa Tests of Basic Skills (ITBS). The data for the implementation study include extensive interviews and surveys with Reading Recovery teachers, teacher leaders, site coordinators, University Training Center directors, members of the i3 project leadership team at The Ohio State University, and principals and first-grade teachers in schools involved in the scale-up. Case studies were also conducted in nine i3 scale-up schools to observe how Reading Recovery operates in different contexts

    Absorption Imaging of Ultracold Atoms on Atom Chips

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    Imaging ultracold atomic gases close to surfaces is an important tool for the detailed analysis of experiments carried out using atom chips. We describe the critical factors that need be considered, especially when the imaging beam is purposely reflected from the surface. In particular we present methods to measure the atom-surface distance, which is a prerequisite for magnetic field imaging and studies of atom surface-interactions.Comment: 12 pages, 8 figures. v2 contains updated figures, modifications to tex

    The Measurement of Rent Inflation

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    Providing for shelter represents a large portion of the typical household budget. Accordingly, rent, paid either to a landlord or to oneself as an owner-occupant, has a large weight in the CPI and in the personal consumption expenditures deflator, resulting in substantial scrutiny of how tenant rent and owners' equivalent rent are measured in these price indexes. In this paper, we describe how the Bureau of Labor Statistics (BLS) estimates tenant rent and owners' equivalent rent. We then estimate alternative inflation rates for tenant rent and owners' equivalent rent based on American Housing Survey data, following BLS methodology as closely as possible. Our alternative tenant rent inflation series is generally consistent with the corresponding BLS series. However, our alternative owners' equivalent rent inflation series is consistently lower than the corresponding BLS series by an amount large enough to have a significant effect on the overall inflation rate. This result is driven by the inverse relationship between rent inflation and the level of monthly housing cost evident in the American Housing Survey data

    dolls/puppets as miniatures - more than small

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    Weitere Hrsg.: Jana Mikota, Philipp SchmerheimDer Themenschwerpunkt der zweiten Ausgabe von de:do lautet: Puppen als Miniaturen – mehr als klein. Puppen und ihre Kontexte beanspruchen hier, ’mehr’ als nur verkleinerte Varianten oder Repliken menschlicher Lebenswelten zu sein. Nicht von ungefähr gelten sie als ein ’Fundort der Größe’ (Bachelard). Als ’kleine Formate’ generieren sie Bilder und Narrative der eigenen Art, die in Funktion und Wirkung offen sind: so bewegen sie sich zwischen Abbildung, Verdichtung und Transformation von Realität, sind Ausdruck von Sehnsüchten und/oder Kontrollbedürfnissen ihrer ErschafferInnen, lösen Bezauberung, Verwunderung oder Befremden aus und ermöglichen ganzheitliche Weltzugänge und Erkenntnis über innere Zusammenhänge. Einmal mehr erweisen sich Puppen als Miniaturen und im Kontext miniaturisierter Welten als hybride Objekte, aufgeladen mit vielerlei Symbolik und Bedeutungsüberschuss. Die Zusammenschau der höchst unterschiedlichen Beiträge im vorliegenden Heft vermittelt eine Ahnung von möglichen Spannungsverhältnissen – zwischen ’klein’ und ’groß’, ’Sichtbarem’ und ’Verstecktem’, ’Realität’ und ’Fiktion’, ’Mimesis’ und ’Poetik’. Das heterogene Themenspektrum unterstreicht die subtile Bedeutung der Puppe als einem besonderen Markenzeichen der ’kleinen Form’ in vielerlei Disziplinen. Die Beiträge stammen aus so unterschiedlichen Fächern bzw. interdisziplinär offenen Fachkulturen wie Archäologie, Anthropologie, Volkskunde, Kinder- und Jugendliteratur, Kunstgeschichte, Spielzeugkunde, Animationsfilm, Bildende Kunst, Mode-Design, Forensik. Ein Interview mit einer jungen Künstlerin, Miszellen und Rezensionen ergänzen die Themenvielfalt.The focus topic of the second edition of the journal denkste: puppe / just a bit of: doll (de:do), a multidisciplinary, peer reviewed online journal for human-doll discourses is: dolls/puppets as miniatures - more than small. Dolls/puppets and their contexts claim to be ’more’ than just miniaturized variants or replicas of human worlds. Thus, it is not by chance that they are regarded as a ’place to find greatness’ (Bachelard). As ’small formats’, they generate images and narratives of their own kind which are open in function and effect: they oscillate between representation, condensation and transformation of reality, expressing longings and/or control needs of their creators and triggering enchantment, amazement or alienation while enabling a holistic access to the world and insight into inner contexts. Arguing in this line, dolls/puppets prove to be miniatures and – in the context of miniaturized worlds –hybrid objects, charged with all sorts of symbolism and excess of meaning. The synopsis of the highly diverse contributions in this issue gives us an idea of possible tensions – between ’small’ and ’large’, ’visible’ and ’hidden’, ’reality’ and ’fiction’, ’mimesis’ and ’poetics’. The heterogeneous range of topics underlines the subtle significance of the doll/puppet as a special trademark of the ’small form’ in many disciplines. The contributions come from subjects as diverse as diverse as archeology, anthropology, folklore, children’s and youth literature, art history, toy studies, animated film, fine arts, fashion design, forensics. An interview with a young artist, miscellaneous aspects as well as reviews complete the variety of topics

    Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication

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    Pharmacological targeting of metabolic processes in cancer must overcome redundancy in biosynthetic pathways. Deoxycytidine (dC) triphosphate (dCTP) can be produced both by the de novo pathway (DNP) and by the nucleoside salvage pathway (NSP). However, the role of the NSP in dCTP production and DNA synthesis in cancer cells is currently not well understood. We show that acute lymphoblastic leukemia (ALL) cells avoid lethal replication stress after thymidine (dT)-induced inhibition of DNP dCTP synthesis by switching to NSP-mediated dCTP production. The metabolic switch in dCTP production triggered by DNP inhibition is accompanied by NSP up-regulation and can be prevented using DI-39, a new high-affinity small-molecule inhibitor of the NSP rate-limiting enzyme dC kinase (dCK). Positron emission tomography (PET) imaging was useful for following both the duration and degree of dCK inhibition by DI-39 treatment in vivo, thus providing a companion pharmacodynamic biomarker. Pharmacological co-targeting of the DNP with dT and the NSP with DI-39 was efficacious against ALL models in mice, without detectable host toxicity. These findings advance our understanding of nucleotide metabolism in leukemic cells, and identify dCTP biosynthesis as a potential new therapeutic target for metabolic interventions in ALL and possibly other hematological malignancies

    Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography

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    Combined inhibition of ribonucleotide reductase and deoxycytidine kinase (dCK) in multiple cancer cell lines depletes deoxycytidine triphosphate pools leading to DNA replication stress, cell cycle arrest and apoptosis. Evidence implicating dCK in cancer cell proliferation and survival stimulated our interest in developing small molecule dCK inhibitors. Following a high throughput screen of a diverse chemical library, a structure-activity relationship study was carried out. Positron Emission Tomography (PET) using (18)F-L-1-(2′-deoxy-2′-FluoroArabinofuranosyl) Cytosine ((18)F-L-FAC), a dCK-specific substrate, was used to rapidly rank lead compounds based on their ability to inhibit dCK activity in vivo. Evaluation of a subset of the most potent compounds in cell culture (IC(50) = ∼1 – 12 nM) using the (18)F-L-FAC PET pharmacodynamic assay identified compounds demonstrating superior in vivo efficacy
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