Pyhän Tuomaan muisto

Arvosteltu teos: The restless corpse: Thomas Aquina's remains as the centre of conflict and cult in late medieval Southern Italy / Marika Räsänen. Turku : Marika Räsänen, 2013

Ars musice

Ars musice, composed in Paris during the late thirteenth century, reflects Johannes de Grocheio\u27s awareness of the complexity of the task of describing music. As the editors note in their introduction, Grocheio is aware of the enormous range of types of music performed in different ways in different places. How can he impose order on this enormous subject matter? He decided to resolve this question by structuring his discussion around the practice of music that he observed in the city of Paris, organized into three main \u27branches\u27: music of the people (musica vulgalis), composite or regular, \u27which they call measured music\u27 (musica mensurata), and ecclesiastical music (musica ecclesiastica), which he claims derives from the other two (AM 6.2). The originality of Grocheio\u27s treatise has attracted considerable scholarly interest. It has long been recognized as a unique source of information about musical life in medieval Paris. Through his treatise, Grocheio enables a modern reader to become aware of the complex auditory environment of that city in the late thirteenth century as well as of its intellectual vitality at a particularly vibrant moment in its history.https://scholarworks.wmich.edu/mip_teamsvaria/1003/thumbnail.jp

The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System

The development and regeneration of myelin by oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), requires profound changes in cell shape that lead to myelin sheath initiation and formation. Here, we demonstrate a requirement for the basal polarity complex protein Scribble in CNS myelination and remyelination. Scribble is expressed throughout oligodendroglial development and is up-regulated in mature oligodendrocytes where it is localised to both developing and mature CNS myelin sheaths. Knockdown of Scribble expression in cultured oligodendroglia results in disrupted morphology and myelination initiation. When Scribble expression is conditionally eliminated in the myelinating glia of transgenic mice, myelin initiation in CNS is disrupted, both during development and following focal demyelination, and longitudinal extension of the myelin sheath is disrupted. At later stages of myelination, Scribble acts to negatively regulate myelin thickness whilst suppressing the extracellular signal-related kinase (ERK)/mitogen-activated protein kinase (MAP) kinase pathway, and localises to non-compact myelin flanking the node of Ranvier where it is required for paranodal axo-glial adhesion. These findings demonstrate an essential role for the evolutionarily-conserved regulators of intracellular polarity in myelination and remyelination

Pyhän Tuomaan muisto

Kirjallisuusarvostel

Manuscripts in Polish libraries copied before 1200 and the expansion of Latin Christendom in the eleventh and twelfth centuries

Mews Constant-J. Manuscripts in Polish libraries copied before 1200 and the expansion of Latin Christendom in the eleventh and twelfth centuries. In: Scriptorium, Tome 56 n°1, 2002. pp. 80-118