A Detailed Observational Analysis of V1324 Sco, the Most Gamma-Ray Luminous Classical Nova to Date

It has recently been discovered that some, if not all, classical novae emit GeV gamma rays during outburst, but the mechanisms involved in the production of the gamma rays are still not well understood. We present here a comprehensive multi-wavelength dataset---from radio to X-rays---for the most gamma-ray luminous classical nova to-date, V1324 Sco. Using this dataset, we show that V1324 Sco is a canonical dusty Fe-II type nova, with a maximum ejecta velocity of 2600 km s$^{-1}$ and an ejecta mass of few $\times 10^{-5}$ M$_{\odot}$. There is also evidence for complex shock interactions, including a double-peaked radio light curve which shows high brightness temperatures at early times. To explore why V1324~Sco was so gamma-ray luminous, we present a model of the nova ejecta featuring strong internal shocks, and find that higher gamma-ray luminosities result from higher ejecta velocities and/or mass-loss rates. Comparison of V1324~Sco with other gamma-ray detected novae does not show clear signatures of either, and we conclude that a larger sample of similarly well-observed novae is needed to understand the origin and variation of gamma rays in novae.Comment: 26 pages, 13 figure

Tamoxifen-Independent Recombination in the RIP-CreER Mouse

The inducible Cre-lox system is a valuable tool to study gene function in a spatial and time restricted fashion in mouse models. This strategy relies on the limited background activity of the modified Cre recombinase (CreER) in the absence of its inducer, the competitive estrogen receptor ligand, tamoxifen. The RIP-CreER mouse (Tg (Ins2-cre/Esr1) 1Dam) is among the few available β-cell specific CreER mouse lines and thus it has been often used to manipulate gene expression in the insulin-producing cells of the endocrine pancreas

Early spectral evolution of classical novae: consistent evidence for multiple distinct outflows

The physical mechanism driving mass ejection during a nova eruption is still poorly understood. Possibilities include ejection in a single ballistic event, a common envelope interaction, a continuous wind, or some combination of these processes. Here we present a study of 12 Galactic novae, for which we have pre-maximum high-resolution spectroscopy. All 12 novae show the same spectral evolution. Before optical peak, they show a slow P Cygni component. After peak a fast component quickly arises, while the slow absorption remains superimposed on top of it, implying the presence of at least two physically distinct flows. For novae with high-cadence monitoring, a third, intermediate-velocity component is also observed. These observations are consistent with a scenario where the slow component is associated with the initial ejection of the accreted material and the fast component with a radiation-driven wind from the white dwarf. When these flows interact, the slow flow is swept up by the fast flow, producing the intermediate component. These colliding flows may produce the gamma-ray emission observed in some novae. Our spectra also show that the transient heavy element absorption lines seen in some novae have the same velocity structure and evolution as the other lines in the spectrum, implying an association with the nova ejecta rather than a pre-existing circumbinary reservoir of gas or material ablated from the secondary. While this basic scenario appears to qualitatively reproduce multi-wavelength observations of classical novae, substantial theoretical and observational work is still needed to untangle the rich diversity of nova properties.Comment: 39 pages, 35 figures, submitted to Ap

Revisiting the classics: On the evolutionary origin of the "Fe II" and "He/N" spectral classes of novae

The optical spectra of novae are characterized by emission lines from the hydrogen Balmer series and either Fe II or He/N, leading to their traditional classification into two spectral classes: "Fe II" and "He/N". For decades, the origins of these spectral features were discussed in the literature in the contexts of different bodies of gas or changes in the opacity of the ejecta, particularly associated with studies by R. E. Williams and S. N. Shore. Here, we revisit these major studies with dedicated, modern data sets, covering the evolution of several novae from early rise to peak all the way to the nebular phase. Our data confirm previous suggestions in the literature that the "Fe II" and "He/N" spectral classes are phases in the spectroscopic evolution of novae driven primarily by changes in the opacity, ionization, and density of the ejecta, and most if not all novae go through at least three spectroscopic phases as their eruptions evolve: an early He/N (phase 1; observed during the early rise to visible peak and characterized by P Cygni lines of He I, N II, and N III), then an Fe II (phase 2; observed near visible peak and characterized by P Cygni lines of Fe II and O I), and then a later He/N (phase 3; observed during the decline and characterized by emission lines of He I. He II, N II, and N III), before entering the nebular phase. This spectral evolution seems to be ubiquitous across novae, regardless of their speed class; however the duration of each of these phase differs based on the speed class of the nova.Comment: 21 pages, 14 figures, 11 tables, Submitted to MNRA

Clustering of Unhealthy Behaviors in the Aerobics Center Longitudinal Study

Background Clustering of unhealthy behaviors has been reported in previous studies; however the link with all-cause mortality and differences between those with and without chronic disease requires further investigation. Objectives To observe the clustering effects of unhealthy diet, fitness, smoking, and excessive alcohol consumption in adults with and without chronic disease and to assess all-cause mortality risk according to the clustering of unhealthy behaviors. Methods Participants were 13,621 adults (aged 20–84) from the Aerobics Center Longitudinal Study. Four health behaviors were observed (diet, fitness, smoking, and drinking). Baseline characteristics of the study population and bivariate relations between pairs of the health behaviors were evaluated separately for those with and without chronic disease using cross-tabulation and a chi-square test. The odds of partaking in unhealthy behaviors were also calculated. Latent class analysis (LCA) was used to assess clustering. Cox regression was used to assess the relationship between the behaviors and mortality. Results The four health behaviors were related to each other. LCA results suggested that two classes existed. Participants in class 1 had a higher probability of partaking in each of the four unhealthy behaviors than participants in class 2. No differences in health behavior clustering were found between participants with and without chronic disease. Mortality risk increased relative to the number of unhealthy behaviors participants engaged in. Conclusion Unhealthy behaviors cluster together irrespective of chronic disease status. Such findings suggest that multi-behavioral intervention strategies can be similar in those with and without chronic disease

Measurements of (tt)over-barH Production and the CP Structure of the Yukawa Interaction between the Higgs Boson and Top Quark in the Diphoton Decay Channel

The first observation of the (tt) over barH process in a single Higgs boson decay channel with the full reconstruction of the final state (H -> gamma gamma) is presented, with a significance of 6.6 standard deviations (sigma). The CP structure of Higgs boson couplings to fermions is measured, resulting in an exclusion of the pure CP-odd structure of the top Yukawa coupling at 3.2 sigma. The measurements are based on a sample of protonproton collisions at a center-of-mass energy root s = 13 TeV collected by the CMS detector at the LHC, corresponding to an integrated luminosity of 137 fb(-1). The cross section times branching fraction of the (tt) over barH process is measured to be sigma B-(tt) over barH(gamma gamma) = 1.56(-0.32)(+0.34) th, which is compatible with the standard model prediction of 1.13(-0.11)(+0.08) fb. The fractional contribution of the CP-odd component is measured to be f(CP)(Hu) = 0.00 +/- 0.33.Peer reviewe

Measurement of the inclusive and differential Higgs boson production cross sections in the leptonic WW decay mode at p root s=13 TeV

Measurements of the fiducial inclusive and differential production cross sections of the Higgs boson in proton-proton collisions at root s = 13 TeV are performed using events where the Higgs boson decays into a pair of W bosons that subsequently decay into a final state with an electron, a muon, and a pair of neutrinos. The analysis is based on data collected with the CMS detector at the LHC during 2016-2018, corresponding to an integrated luminosity of 137 fb(-1). Production cross sections are measured as a function of the transverse momentum of the Higgs boson and the associated jet multiplicity. The Higgs boson signal is extracted and simultaneously unfolded to correct for selection efficiency and resolution effects using maximum-likelihood fits to the observed distributions in data. The integrated fiducial cross section is measured to be 86.5 +/- 9.5 fb, consistent with the Standard Model expectation of 82.5 +/- 4.2 fb. No significant deviation from the Standard Model expectations is observed in the differential measurements.Peer reviewe