On the Potential of Leptonic Minimal Flavour Violation

Minimal Flavour Violation can be realized in several ways in the lepton sector due to the possibility of Majorana neutrino mass terms. We derive the scalar potential for the fields whose background values are the Yukawa couplings, for the simplest See-Saw model with just two right-handed neutrinos, and explore its minima. The Majorana character plays a distinctive role: the minimum of the potential allows for large mixing angles -in contrast to the simplest quark case- and predicts a maximal Majorana phase. This points in turn to a strong correlation between neutrino mass hierarchy and mixing pattern.Comment: 6 pages; version published on Physics Letters

Analysis of General Power Counting Rules in Effective Field Theory

We derive the general counting rules for a quantum effective field theory (EFT) in $\mathsf{d}$ dimensions. The rules are valid for strongly and weakly coupled theories, and predict that all kinetic energy terms are canonically normalized. They determine the energy dependence of scattering cross sections in the range of validity of the EFT expansion. We show that the size of cross sections is controlled by the $\Lambda$ power counting of EFT, not by chiral counting, even for chiral perturbation theory ($\chi$PT). The relation between $\Lambda$ and $f$ is generalized to $\mathsf{d}$ dimensions. We show that the naive dimensional analysis $4\pi$ counting is related to $\hbar$ counting. The EFT counting rules are applied to $\chi$PT, low-energy weak interactions, Standard Model EFT and the non-trivial case of Higgs EFT.Comment: V2: more details and examples added; version published in journal. 17 pages, 4 figures, 2 table

Stem Cells in Domestic Animals: Applications in Health and Production

In the last decade, researchers described Mesenchymal Stem/stromal cells (MSCs) as a possible population of cells for cell-based therapies in regenerative medicine, both for humans and animals. The aim of this first article (and the aim of the next books in this collection) is to gather high-quality research and review articles that could broaden knowledge regarding the role of MSCs in domestic animals’ health and production

Stem cells from foetal adnexa and fluid in domestic animals: An update on their features and clinical application

Over the past decade stem cell research has emerged as an area of major interest for its potential in regenerative medicine applications. This is in constant need of new cell sources to conceive regenerative medicine approaches for diseases that are still without therapy. Scientists drew the attention toward alternative sources such as foetal adnexa and fluid, since these sources possess many advantages: first of all, cells can be extracted from discarded foetal material and it is noninvasive for the patient and inexpensive, secondly abundant stem cells can be obtained and finally, these stem cell sources are free from ethical considerations. Cells derived from foetal adnexa and fluid preserve some of the characteristics of the primitive embryonic layers from which they originate. Many studies have demonstrated the differentiation potential in vitro and in vivo toward mesenchymal and non-mesenchymal cell types; in addition the immune-modulatory properties make these cells a good candidate for allo- and xenotransplantation. Naturally occurring diseases in domestic animals can be more ideal as disease model of human genetic and acquired diseases and could help to define the potential therapeutic use efficiency and safety of stem cells therapies. This review offers an update on the state of the art of characterization of domestic animals MSCs derived from foetal adnexa and fluid and on the latest findings in pre-clinical or clinical setting of the stem cell populations isolated from these sources

Spatial clustering of mental disorders and associated characteristics of the neighbourhood context in Malmö, Sweden, in 2001

Study objective: Previous research provides preliminary evidence of spatial variations of mental disorders and associations between neighbourhood social context and mental health. This study expands past literature by (1) using spatial techniques, rather than multilevel models, to compare the spatial distributions of two groups of mental disorders (that is, disorders due to psychoactive substance use, and neurotic, stress related, and somatoform disorders); and (2) investigating the independent impact of contextual deprivation and neighbourhood social disorganisation on mental health, while assessing both the magnitude and the spatial scale of these effects. Design: Using different spatial techniques, the study investigated mental disorders due to psychoactive substance use, and neurotic disorders. Participants: All 89 285 persons aged 40–69 years residing in Malmö, Sweden, in 2001, geolocated to their place of residence. Main results: The spatial scan statistic identified a large cluster of increased prevalence in a similar location for the two mental disorders in the northern part of Malmö. However, hierarchical geostatistical models showed that the two groups of disorders exhibited a different spatial distribution, in terms of both magnitude and spatial scale. Mental disorders due to substance consumption showed larger neighbourhood variations, and varied in space on a larger scale, than neurotic disorders. After adjustment for individual factors, the risk of substance related disorders increased with neighbourhood deprivation and neighbourhood social disorganisation. The risk of neurotic disorders only increased with contextual deprivation. Measuring contextual factors across continuous space, it was found that these associations operated on a local scale. Conclusions: Taking space into account in the analyses permitted deeper insight into the contextual determinants of mental disorders

Electron conductivity and second generation Composite Fermions

The relation between the conductivity tensors of Composite Fermions and electrons is extended to second generation Composite Fermions. It is shown that it crucially depends on the coupling matrix for the Chern-Simons gauge field. The results are applied to a model of interacting Composite Fermions that can explain both the anomalous plateaus in spin polarization and the corresponding maxima in the resistivity observed in recent transport experiments

CP violation with a dynamical Higgs

We determine the complete set of independent gauge and gauge-Higgs CP-odd effective operators for the generic case of a dynamical Higgs, up to four derivatives in the chiral expansion. The relation with the linear basis of dimension six CP-odd operators is clarified. Phenomenological applications include bounds inferred from electric dipole moment limits, and from present and future collider data on triple gauge coupling measurements and Higgs signals.Comment: 41 pages, 3 figures; V2: citations added, typos corrected, version published on JHE

Higgs ultraviolet softening

We analyze the leading effective operators which induce a quartic momentum dependence in the Higgs propagator, for a linear and for a non-linear realization of electroweak symmetry breaking. Their specific study is relevant for the understanding of the ultraviolet sensitivity to new physics. Two methods of analysis are applied, trading the Lagrangian coupling by: i) a "ghost" scalar, after the Lee-Wick procedure; ii) other effective operators via the equations of motion. The two paths are shown to lead to the same effective Lagrangian at first order in the operator coefficients. It follows a modification of the Higgs potential and of the fermionic couplings in the linear realization, while in the non-linear one anomalous quartic gauge couplings, Higgs-gauge couplings and gauge-fermion interactions are induced in addition. Finally, all LHC Higgs and other data presently available are used to constrain the operator coefficients; the future impact of $pp\to\text{4 leptons}$ data via off-shell Higgs exchange and of vector boson fusion data is considered as well. For completeness, a summary of pure-gauge and gauge-Higgs signals exclusive to non-linear dynamics at leading-order is included.Comment: 31 pages, 3 figures, 7 table