227 research outputs found
Il Cinema VR come esperienza immersiva archi-schermica
Il saggio intende proporre una riflessione teorica nei confronti del Cinema VR, pratica artistica recente che ha visto la luce applicando lâapparato tecnico ed estetico della Virtual Reality alla narrativitĂ e agli stilemi cinematografici. Dopo una breve premessa etimologica attorno allâidea di immersivitĂ , utile a circoscrivere il campo dâindagine, viene introdotto lâoggetto di studio suddetto, cercando di analizzarne la natura mediale e descrivendo perciĂČ questâultima attraverso alcune riflessioni di Citton e di Auslander. Ci si sofferma in seguito sul pensiero di Carbone e sulla sua âfilosofia-schermiâ, tentando di associare al Cinema VR lââidea sensibileâ di âarchi-schermoâ, attraverso un discorso sulla percezione tra corpo e schermo. Infine, dopo alcune precisazioni di carattere tecnico, si cerca di rilanciare il discorso teorico appoggiandosi allâanalisi di DâAloia, cercando di esplicitare quanto sviluppato lungo la trattazione applicandolo, evidenziandone cosĂŹ da ultimo anche possibili ampliamenti futuri.The essay aims to propose a theoretical reflection about VR Cinema, a recent artistic practice born by applying the technical and aesthetic apparatus of Virtual Reality to narrative and stylistic features of Cinema. After a brief etymological premise around the idea of immersivity, useful for circumscribing the field of investigation, we will introduce the Cinema VR, trying to analyse its media nature describing it through some reflections by Citton and by Auslander. We then will focus on Carboneâs âphilosophy-screensâ, trying to associate the âsensitive ideaâ of âarche-screenâ with the Cinema VR, through a discussion on the perception between body and screen. In the end, after some clarifications of a technical nature, we will return to the theoretical exploration using the analysis of DâAloia. In this way we will try to explain what we developed throughout the discussion, highlighting also possible future extensions
Global constraints on absolute neutrino masses and their ordering
Within the standard three-neutrino framework, the absolute neutrino masses
and their ordering (either normal, NO, or inverted, IO) are currently unknown.
However, the combination of current data coming from oscillation experiments,
neutrinoless double beta decay searches, and cosmological surveys, can provide
interesting constraints for such unknowns in the sub-eV mass range, down to
O(0.1) eV in some cases. We discuss current limits on absolute neutrino mass
observables by performing a global data analysis, that includes the latest
results from oscillation experiments, neutrinoless double beta decay bounds
from the KamLAND-Zen experiment, and constraints from representative
combinations of Planck measurements and other cosmological data sets. In
general, NO appears to be somewhat favored with respect to IO at the level of
~2 sigma, mainly by neutrino oscillation data (especially atmospheric),
corroborated by cosmological data in some cases. Detailed constraints are
obtained via the chi^2 method, by expanding the parameter space either around
separate minima in NO and IO, or around the absolute minimum in any ordering.
Implications for upcoming oscillation and non-oscillation neutrino experiments,
including beta-decay searches, are also discussed.Comment: 17 pages, including 3 tables and 11 figure
Limitations to the Accuracy of Cosmic Background Radiation Anisotropy Measurements: Atmospheric Fluctuations
We discuss the ultimate limits posed by atmospheric fluctuations to observations of cosmic background anisotropies (CBAs) in ground-based and balloon-borne experiments both in the radio and millimetric regions. We present correlation techniques useful in separating CBAs from atmospheric fluctuations. An experimental procedure is discussed for testing a site in view of possible CBA observations. Four sites with altitudes ranging from 0 up to 3.5 km have been tested
An improved limit on the neutrino mass with CMB and redshift-dependent halo bias-mass relations from SDSS, DEEP2, and Lyman-Break Galaxies
We use measurements of luminosity-dependent galaxy bias at several different
redshifts, SDSS at , DEEP2 at and LBGs at , combined with
WMAP five-year cosmic microwave background anisotropy data and SDSS Red
Luminous Galaxy survey three-dimensional clustering power spectrum to put
constraints on cosmological parameters. Fitting this combined dataset, we show
that the luminosity-dependent bias data that probe the relation between halo
bias and halo mass and its redshift evolution are very sensitive to sum of the
neutrino masses: in particular we obtain the upper limit of eV at the 95% confidence level for a
model, with a equal to (1). When we
allow the dark energy equation of state parameter to vary we find
for a general model with the 95% confidence
level upper limit on the neutrino masses at eV. The
constraint on the dark energy equation of state further improves to
when using also ACBAR and supernovae Union data, in addition
to above, with a prior on the Hubble constant from the Hubble Space Telescope.Comment: 9 pages, 6 figures, submitted to PR
Future weak lensing constraints in a dark coupled universe
Coupled cosmologies can predict values for the cosmological parameters at low
redshifts which may differ substantially from the parameters values within
non-interacting cosmologies. Therefore, low redshift probes, as the growth of
structure and the dark matter distribution via galaxy and weak lensing surveys
constitute a unique tool to constrain interacting dark sector models. We focus
here on weak lensing forecasts from future Euclid and LSST-like surveys
combined with the ongoing Planck cosmic microwave background experiment. We
find that these future data could constrain the dimensionless coupling to be
smaller than a few . The coupling parameter is strongly
degenerate with the cold dark matter energy density and the
Hubble constant .These degeneracies may cause important biases in the
cosmological parameter values if in the universe there exists an interaction
among the dark matter and dark energy sectors.Comment: 8 pages, 6 figure
Determining the Neutrino Mass Hierarchy with Cosmology
The combination of current large scale structure and cosmic microwave
background (CMB) anisotropies data can place strong constraints on the sum of
the neutrino masses. Here we show that future cosmic shear experiments, in
combination with CMB constraints, can provide the statistical accuracy required
to answer questions about differences in the mass of individual neutrino
species. Allowing for the possibility that masses are non-degenerate we combine
Fisher matrix forecasts for a weak lensing survey like Euclid with those for
the forthcoming Planck experiment. Under the assumption that neutrino mass
splitting is described by a normal hierarchy we find that the combination
Planck and Euclid will possibly reach enough sensitivity to put a constraint on
the mass of a single species. Using a Bayesian evidence calculation we find
that such future experiments could provide strong evidence for either a normal
or an inverted neutrino hierachy. Finally we show that if a particular neutrino
hierachy is assumed then this could bias cosmological parameter constraints,
for example the dark energy equation of state parameter, by > 1\sigma, and the
sum of masses by 2.3\sigma.Comment: 9 pages, 6 figures, 3 table
European medicines agency approval summary: zaltrap for the treatment of patients with oxaliplatin-resistant metastatic colorectal cancer
On 1 February 2013, a marketing authorisation valid throughout the European Union was issued for aflibercept (Zaltrap) in combination with irinotecan/5-fluorouracil/ folinic acid chemotherapy for the treatment of adults with metastatic colorectal cancer resistant to or progressive after an oxaliplatin-containing regimen. Aflibercept is a recombinant fusion protein which blocks the activation of vascular endothelial growth factor (VEGF) receptors and the proliferation of endothelial cells, acting as a soluble decoy receptor that binds to VEGF-A with higher affinity than its native receptors, as well as placental growth factor and VEGF-B. The use of aflibercept was studied in a randomised, double-blind, placebo-controlled phase III study, in patients with metastatic colorectal cancer (mCRC) who had previously been treated with an oxaliplatinbased treatment with or without prior bevacizumab. Aflibercept (n=612) was compared with placebo (n=614), both in combination with FOLFIRI (infusional fluorouracil, leucovorin and irinotecan). The primary endpoint of the study was overall survival (OS). The median OS in the intent-to-treat population was 13.5 months in subjects treated with aflibercept compared with 12.1 months for subjects in the control arm (stratified HR=0.817, 95% CI 0.714 to 0.935, stratified pvalue=0.0032). The frequency of adverse events was higher in the aflibercept arm compared with the placebo arm, reflecting the toxicity profile of anti-VEGF agents in combination with chemotherapy. This paper is based on the scientific review of the application leading to approval of aflibercept in the EU. The detailed scientific assessment report and product information for this product are available on the European Medicines Agency website
The Sunyaev-Zeldovich MITO Project
Compton scattering of the cosmic microwave background radiation by electrons
in the hot gas in clusters of galaxies - the Sunyaev-Zeldovich effect - has
long been recognized as a uniquely important feature, rich in cosmological and
astrophysical information. We briefly describe the effect, and emphasize the
need for detailed S-Z and X-ray measurements of nearby clusters in order to use
the effect as a precise cosmological probe. This is the goal of the MITO
project, whose first stage consisted of observations of the S-Z effect in the
Coma cluster. We report the results of these observations.Comment: To appear in Proceedings of `Understanding our Universe at the close
of XXth century', School held Apr 25 - May 6 2000, Cargese, 16 pages LaTeX, 2
figures ps (using elsart.sty & elsart.cls), text minor revisio
CMB Polarization Systematics, Cosmological Birefringence and the Gravitational Waves Background
Cosmic Microwave Background experiments must achieve very accurate
calibration of their polarization reference frame to avoid biasing the
cosmological parameters. In particular, a wrong or inaccurate calibration might
mimic the presence of a gravitational wave background, or a signal from
cosmological birefringence, a phenomenon characteristic of several
non-standard, symmetry breaking theories of electrodynamics that allow for
\textit{in vacuo} rotation if the polarization direction of the photon.
Noteworthly, several authors have claimed that the BOOMERanG 2003 (B2K)
published polarized power spectra of the CMB may hint at cosmological
birefringence. Such analyses, however, do not take into account the reported
calibration uncertainties of the BOOMERanG focal plane. We develop a formalism
to include this effect and apply it to the BOOMERanG dataset, finding a
cosmological rotation angle . We also
investigate the expected performances of future space borne experiment, finding
that an overall miscalibration larger then for Planck and
for EPIC, if not properly taken into account, will produce a bias on the
constraints on the cosmological parameters and could misleadingly suggest the
presence of a GW background.Comment: 10 pages, 3 figure
Amplitudes of thermal and kinetic Sunyaev-Zel'dovich signals from small-scale CMB anisotropies
While the arcminute-scale Cosmic Microwave Background (CMB) anisotropies are
due to secondary effects, point sources dominate the total anisotropy power
spectrum. At high frequencies the point sources are primarily in the form of
dusty, star-forming galaxies. Both Herschel and Planck have recently measured
the anisotropy power spectrum of cosmic infrared background (CIB) generated by
dusty, star-forming galaxies from degree to sub-arcminute angular scales,
including the non-linear clustering of these galaxies at multipoles of 3000 to
6000 relevant to CMB secondary anisotropy studies. We scale the CIB angular
power spectra to CMB frequencies and interpret the combined WMAP-7 year and
arcminute-scale Atacama Cosmology Telescope (ACT) and South Pole Telescope
(SPT) CMB power spectra measurements to constrain the Sunyaev-Zel'dovich (SZ)
effects. Allowing the CIB clustering amplitude to vary, we constrain the
amplitudes of thermal and kinetic SZ power spectra at 150 GHz.Comment: 8 pages, 3 figures, 2 table
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