Analysis On Energy Consumption In The Health Sector And Energy Saving Measures

The services sector within which is also the Health Sector is a sector with particular importance given that the majority of consumers in this sector are public services consumers. Under Directive 2006/32/EC this sector should play promoter role of developments in terms of improving energy efficiency. Given the fact that many projects in the field of energy efficiency mainly funded by donors aimed the Public Health sector because besides achieving energy savings there should also be reached the comfort level within the building as most of the Health care buildings in Kosovo lack the basic comfort level regarding internal temperature, air flow and lighting

A Case of Allergic Dermatitis after Self-Treatment with Propolis: Case Report

Background:  Propolis or bee-glue is used as adjuvant in the therapy because of its antiseptic, anti-inflammatory, anesthetic and antibacterial properties. Propolis is found in a number of products such as cosmetics, shampoos, toothpastes, lip balms, creams and ointments. In dermatology propolis has been used for wound healing, treatment of ulcers and eczema, and regeneration of the skin. The sensitizing properties of propolis have been reported in the literature.Aim: The aim of this study was to present a case of allergic contact dermatitis after self-treatment with propolis.Methods: We report a case of 46 years old man who presented severe vesiculo-bullous elements on the leg after the treatment with bee-glue for the eczematous elements.Results: The diagnosis of allergic contact dermatitis to propolis was confirmed due to patch tests.Conclusions: Here we show that allergic contact dermatitis from propolis should be taken in consideration if an allergic reaction is evident. Dermatologists and general physicians should be aware of propolis as an important allergen that can cause Allergic Contact Dermatitis. The therapeutic use of propolis should be performed under medical advisory

A Severe Case of Wheat-Dependent Exercise-Induced Anaphylaxis in Adulthood

Food-dependent exercise-induced anaphylaxis (FDEIA), is a severe form of allergy for which the ingestion of a specific food, usually before physical exercise induces symptoms of anaphylaxis. Patients typically have IgE antibodies to the food that triggers the reactions; however, the symptoms appear only if the co-factors act together. The most common reported cause of these reactions seems to be wheat. In some cases FDEIA is displayed even when the food is eaten immediately after exercise, showing that in FDEIA, not the sequence but rather the coincidence of triggering factors use, is of crucial importance. The risk to develop anaphylaxis in these patients depends on the presence and, in some cases, on the amount of cofactors of anaphylaxis. There are lots of evidences about the role of NSAIDs as cofactors of anaphylaxis

Clinically relevant subgroups in COPD and asthma

As knowledge of airways disease has grown, it has become apparent that neither chronic obstructive pulmonary disease (COPD) nor asthma is a simple, easily defined disease. In the past, treatment options for both diseases were limited; thus, there was less need to define subgroups. As treatment options have grown, so has our need to predict who will respond to new drugs. To date, identifying subgroups has been largely reported by detailed clinical characterisation or differences in pathobiology. These subgroups are commonly called "phenotypes"; however, the problem of defining what constitutes a phenotype, whether this should include comorbid diseases and how to handle changes over time has led to the term being used loosely. In this review, we describe subgroups of COPD and asthma patients whose clinical characteristics we believe have therapeutic or major prognostic implications specific to the lung, and whether these subgroups are constant over time. Finally, we will discuss whether the subgroups we describe are common to both asthma and COPD, and give some examples of how treatment might be tailored in patients where the subgroup is clear, but the label of asthma or COPD is not

Coat Polymorphism in Eurasian Lynx: Adaptation to Environment or Phylogeographic Legacy?

We studied the relationship between the variability and contemporary distribution of pelage phenotypes in one of most widely distributed felid species and an array of environmental and demographic conditions. We collected 672 photographic georeferenced records of the Eurasian lynx throughout Eurasia. We assigned each lynx coat to one of five phenotypes. Then we fitted the coat patterns to different environmental and anthropogenic variables, as well as the effective geographic distances from inferred glacial refugia. A majority of lynx were either of the large spotted (41.5%) or unspotted (uniform, 36.2%) phenotype. The remaining patterns (rosettes, small spots and pseudo-rosettes) were represented in 11.0%, 7.4%, and 3.9% of samples, respectively. Although various environmental variables greatly affected lynx distribution and habitat suitability, it was the effect of least-cost distances from locations of the inferred refugia during the Last Glacial Maximum that explained the distribution of lynx coat patterns the best. Whereas the occurrence of lynx phenotypes with large spots was explained by the proximity to refugia located in the Caucasus/Middle East, the uniform phenotype was associated with refugia in the Far East and Central Asia. Despite the widely accepted hypothesis of adaptive functionality of coat patterns in mammals and exceptionally high phenotypic polymorphism in Eurasian lynx, we did not find well-defined signs of habitat matching in the coat pattern of this species. Instead, we showed how the global patterns of morphological variability in this large mammal and its environmental adaptations may have been shaped by past climatic change.publishedVersio

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis

Membranous Nephropathy (MN) is a rare autoimmune cause of kidney failure. Here we report a genome-wide association study (GWAS) for primary MN in 3,782 cases and 9,038 controls of East Asian and European ancestries. We discover two previously unreported loci, NFKB1 (rs230540, OR = 1.25, P = 3.4 × 10-12) and IRF4 (rs9405192, OR = 1.29, P = 1.4 × 10-14), fine-map the PLA2R1 locus (rs17831251, OR = 2.25, P = 4.7 × 10-103) and report ancestry-specific effects of three classical HLA alleles: DRB1*1501 in East Asians (OR = 3.81, P = 2.0 × 10-49), DQA1*0501 in Europeans (OR = 2.88, P = 5.7 × 10-93), and DRB1*0301 in both ethnicities (OR = 3.50, P = 9.2 × 10-23 and OR = 3.39, P = 5.2 × 10-82, respectively). GWAS loci explain 32% of disease risk in East Asians and 25% in Europeans, and correctly re-classify 20-37% of the cases in validation cohorts that are antibody-negative by the serum anti-PLA2R ELISA diagnostic test. Our findings highlight an unusual genetic architecture of MN, with four loci and their interactions accounting for nearly one-third of the disease risk

Allergic Acute Coronary Syndrome: A Case Report and Literature Review

Introduction: Kounis Syndrome was first described in 1991 by Kounis and Zavras as “the concurrence of chest pain during an allergic reaction, accompanied by clinical laboratory findings of classical angina pectoris caused by inflammatory mediators released during the allergic insult” [1]. The mechanism of Kounis Syndrome most likely involves the release of cytokines through mast-cell degranulation, which leads to coronary vasospasm and atheromatous plaque erosion or rupture following the allergic reaction to an allergen.[2] The treatment is specific to acute coronary syndrome and anaphylaxis, with the added complication that the drugs used, while indicated in each of the two disorders separately, may present contradictions when administered jointly in one patient.[3] The purpose of this review is to briefly revise the existing literature regarding its overlooked diagnosis and contradictory joint management of anaphylaxis and acute coronary syndrome. We will conduct a brief review of the current literature on Kounis Syndrome while describing a suspected case of a female patient presented with both anaphylaxis symptoms and angina pectoris. Conclusions: Kounis syndrome is defined as the co-incidental occurrence of an acute coronary syndrome with hypersensitivity reactions following an allergic reaction. Treatment of allergic reactions may be sufficient in type I KS. In contrast, coronary intervention is needed in the other two types, accompanied by vasodilator drugs, including nitrates and calcium antagonists, each of which may have contradictory effects

THE ROLE AND ASSOCIATION OF BODY HEIGHT AND WEIGHT OF THE PERFORMANCE OF MOTOR ABILITIES IN SOCCER PLAYERS

The youth ability to perform high-speed running actions such as sprints to win possession of the ball or to pass defending players is believed to be critical to the outcome of soccer matches (Bradley et al., 2009). As such, sprint ability has been reported to be a physical prerequisite for professional soccer players (Cometti et al., 2001; Gissiset al., 2006). The goal of this study was to evaluate the role and association of body weight and height in the performance of motor abilities in youth soccer players. Methods: The subjects of this study were 64 youth soccer players with an average weight 47.5 kg (+/- 7.3 kg) and height 157.3 cm (+/- 7.4cm). Anthropometrics were measured as body height and weight in youth. The subject underwent to perform a speed test (10m and 30m sprint test, 10x5m speed agility test) and standing long jump to evaluate explosive power to lower limbs. Analysis of correlation was performed to find out if there was the association. Result: The results show that; body weight were correlated with motor abilities as follows; body weight with 10m sprint test (r= -0.054; sig= 0.671), body weight with 30m sprint test (r= -0.049; sig= 0.724), body weight with 10x5m agility test (r= -0.025; sig= 0.871), body weight with standing long jump test (r= 0.193; sig= 0.163). While body height were correlated with motor abilities as follows; body height with 10m sprint test (r= -0.051; sig= 0.6), body height with 30m sprint test (r= -0.054; sig= 0.671), body height with 10x5m agility test (r= -0.018; sig= 0.909), body height with standing long jump test (r= 0.215; sig= 0.119). Conclusion: There was a negative but no significant correlation between body weight and body height with motor abilities with regard to speed and agility. There was no significant correlation between body weight and height with explosive power of lower limbs. This results even though found no significance correlation but negative correlation, suggest that coaches should be careful with anthropometrics variables of their players in designing athletic program with regard to speed and agilit