Recent Progress and Next Steps for the MATHUSLA LLP Detector

We report on recent progress and next steps in the design of the proposed MATHUSLA Long Lived Particle (LLP) detector for the HL-LHC as part of the Snowmass 2021 process. Our understanding of backgrounds has greatly improved, aided by detailed simulation studies, and significant R&D has been performed on designing the scintillator detectors and understanding their performance. The collaboration is on track to complete a Technical Design Report, and there are many opportunities for interested new members to contribute towards the goal of designing and constructing MATHUSLA in time for HL-LHC collisions, which would increase the sensitivity to a large variety of highly motivated LLP signals by orders of magnitude.Comment: Contribution to Snowmass 2021 (EF09, EF10, IF6, IF9), 18 pages, 12 figures. v2: included additional endorser

Purakau Myths & Legends Mitos y Leyendas | Waikato Museum

All cultures have myths and legends woven into the fabric of their traditions. Eleven artists and fourteen writers from Aotearoa, Cuba, Mexico and Spain respond to the idea of myths and legends, creating twelve posters that tell of legends and contemporary political myths, challenging our complacency with war, the planet, colonisation and life. Over nine months, we will reveal to you four posters at a time... allowing each to tell their tale in Maaori, Spanish and English. We encourage you to read these walls

Pūrākau / Myths and legends / Mitos y leyendas

Trilingual Publication (English, Spanish and Te Reo Maori) Posters from Aotearoa, Cuba & Mexico Pūrākau = a Maori term referring to myths, legends and "lessons for life" Poster = a print-based medium that uses visual devices to form opinion, persuade, provoke, unite and divide us. In 2009 Xavier Meade (NZ) and Flor de Lis López Hernández (Cuba) invited twelve artists from Aotearoa, Cuba and Mexico to produce posters in response to the theme of ‘Pūrākau’. The artists activated a diverse range of indigenous myths and legends: “The Tangler”, “the Disappearance of Matias Perez”, “Origin of the Poisonous Guao Plant” among others. The stories are deeply embedded in their cultures or origin, but the underlying themes resonate across cultures. The craftsmanship of the posters is exquisite. The Cuban contributors come from a long-standing tradition of handcrafted screen-printing which has been maintained since the Cuban Revolution. All posters are made in their country of origin, through screen-print and lithographic processes. Pūrākau follows in the footsteps of Xavier Meade’s highly successful “Aotearoa Liberators” project, a collaborative exhibition of posters that found an audience in New Zealand, Mexico and Cuba. http://ramp.mediarts.net.nz/aotearoaliberators/ ---------- Pūrākau / Myths and Legends / Mitos y Leyendas is a publication accompanying the international poster project Pūrākau. Curated by expatriate Mexican artist Xavier Meade together with Cuban curator Flor de Lis López Hernández, the project exchanges the shape of poet-colonial resistance in the form of indigenous myths and legends. Taking its cue from Cuban revolutionary design, the collected posters use bold graphic imagery to convey pūrākau, or ‘lessons for life’. This touring exhibition brought together twelve leading artists from Cuba, Mexico and Aotearoa New Zealand to exchange indigenous myths and legends through poster design: Denis O'Connor, Natalie Robertson, Michael Reed, Claudio Sotolongo Menéndez, Giselle Monzón Calero, Michele Miyares Hollands, Eric Silva, Mario & Yesca, Arturo Meade and Carlos Pez. The publication is presented in three languages – English, Māori and Spanish – and features writing by Jon Bywater, Danny Butt, Yani Monzón Calero, Ernesto Pérez Castillo, Claudio Sotolongo, Carlos Meade, Luis Delaç, Los Appo Stoles Irreverentes, the curators and many of the artists

Aotearoa Liberators & Púrákau (Myths and Legends - Mitos y leyendas)

Two series of limited edition Posters with contributions from Mexican, Cuban and New Zealand asrists, designers and writers

Improving Lung Function in Severe Heterogenous Emphysema with the Spiration Valve System (EMPROVE). A Multicenter, Open-Label Randomized Controlled Clinical Trial

Less invasive, nonsurgical approaches are needed to treat severe emphysema. To evaluate the effectiveness and safety of the Spiration Valve System (SVS) versus optimal medical management. In this multicenter, open-label, randomized, controlled trial, subjects aged 40 years or older with severe, heterogeneous emphysema were randomized 2:1 to SVS with medical management (treatment) or medical management alone (control). The primary efficacy outcome was the difference in mean FEV from baseline to 6 months. Secondary effectiveness outcomes included: difference in FEV responder rates, target lobe volume reduction, hyperinflation, health status, dyspnea, and exercise capacity. The primary safety outcome was the incidence of composite thoracic serious adverse events. All analyses were conducted by determining the 95% Bayesian credible intervals (BCIs) for the difference between treatment and control arms. Between October 2013 and May 2017, 172 participants (53.5% male; mean age, 67.4 yr) were randomized to treatment (  = 113) or control (  = 59). Mean FEV showed statistically significant improvements between the treatment and control groups-between-group difference at 6 and 12 months, respectively, of 0.101 L (95% BCI, 0.060-0.141) and 0.099 L (95% BCI, 0.048-0.151). At 6 months, the treatment group had statistically significant improvements in all secondary endpoints except 6-minute-walk distance. Composite thoracic serious adverse event incidence through 6 months was greater in the treatment group (31.0% vs. 11.9%), primarily due to a 12.4% incidence of serious pneumothorax. In patients with severe heterogeneous emphysema, the SVS shows significant improvement in multiple efficacy outcomes, with an acceptable safety profile.Clinical trial registered with www.clinicaltrials.gov (NCT01812447)

Traumatic brain injury : integrated approaches to improve prevention, clinical care, and research

Rahul Raj on työryhmän InTBIR Participants Investigators jäsen.Peer reviewe

Explore the lifetime frontier with MATHUSLA

The observation of long-lived particles at the LHC would reveal physics beyond the Standard Model, could account for the many open issues in our understanding of our universe, and conceivably point to a more complete theory of the fundamental interactions. Such long-lived particle signatures are fundamentally motivated and can appear in virtually every theoretical construct that address the Hierarchy Problem, Dark Matter, Neutrino Masses and the Baryon Asymmetry of the Universe. We describe in this document a large detector, MATHUSLA, located on the surface above an HL-LHC $pp$ interaction point, that could observe long-lived particles with lifetimes up to the Big Bang Nucleosynthesis limit of 0.1 s. We also note that its large detector area allows MATHUSLA to make important contributions to cosmic ray physics. Because of the potential for making a major breakthrough in our conceptual understanding of the universe, long-lived particle searches should have the highest level of priority.The observation of long-lived particles at the LHC would reveal physics beyond the Standard Model and could account for the many open issues in our understanding of our universe. Long-lived particle signatures are well motivated and can appear in many theoretical constructs that address the Hierarchy Problem, Dark Matter, Neutrino Masses and the Baryon Asymmetry of the Universe. With the current experiments at the particle accelerators, no search strategy will be able to observe the decay of neutral long-lived particles with masses above GeV and lifetimes at the limit set by Big Bang Nucleosynthesis, cτ ∼ 107–108 m. The MATHUSLA detector concept (MAssive Timing Hodoscope for Ultra-Stable neutraL pArticles) will be presented. It can be implemented on the surface above ATLAS or CMS detectors in time for the high-luminosity LHC operations, to search for neutral long-lived particles with lifetimes up to the BBN limit. The large area of the detector allows MATHUSLA to make important contributions also to cosmic-ray physics. We will also report on the analysis of data collected by the test stand installed on the surface above the ATLAS detector, the on-going background studies, and plans for the MATHUSLA detector