How self-organization can guide evolution

Self-organization and natural selection are fundamental forces that shape the natural world. Substantial progress in understanding how these forces interact has been made through the study of abstract models. Further progress may be made by identifying a model system in which the interaction between self-organization and selection can be investigated empirically. To this end, we investigate how the self-organizing thermoregulatory huddling behaviours displayed by many species of mammals might influence natural selection of the genetic components of metabolism. By applying a simple evolutionary algorithm to a wellestablished model of the interactions between environmental, morphological, physiological and behavioural components of thermoregulation, we arrive at a clear, but counterintuitive, prediction: rodents that are able to huddle together in cold environments should evolve a lower thermal conductance at a faster rate than animals reared in isolation. The model therefore explains how evolution can be accelerated as a consequence of relaxed selection, and it predicts how the effect may be exaggerated by an increase in the litter size, i.e. by an increase in the capacity to use huddling behaviours for thermoregulation. Confirmation of these predictions in future experiments with rodents would constitute strong evidence of a mechanism by which self-organization can guide natural selection

Data Recovery from SCATHA Satellite

This document gives a brief description of the SCATHA (P78-2) satellite and consolidates into one location information relevant to the generation of the SCATHA Summary Data parameters for the European Space Agency (ESA), under ESTEC Contract No. 11006/94/NL/CC, and the National Aeronautics and Space Administration (NASA), under Grant No. NAGW-414 1. Included are descriptions of the instruments from which the Summary Data parameters are generated, their derivation, and archival. Any questions pertaining to the Summary Data parameters should be directed to Dr. Joseph Fennell

Comparative physiology of Australian quolls (Dasyurus; Marsupialia)

Quolls (Dasyurus) are medium-sized carnivorous dasyurid marsupials. Tiger (3,840 g) and eastern quolls (780 g) are mesic zone species, northern quolls (516 g) are tropical zone, and chuditch (1,385 g) were once widespread through the Australian arid zone. We found that standard physiological variables of these quolls are consistent with allometric expectations for marsupials. Nevertheless, inter-specific patterns amongst the quolls are consistent with their different environments. The lower T ^sub b^ of northern quolls (34°C) may provide scope for adaptive hyperthermia in the tropics, and they use torpor for energy/water conservation, whereas the larger mesic species (eastern and tiger quolls) do not appear to. Thermolability varied from little in eastern (0.035°C °C^sup -1^) and tiger quolls (0.051°C ºC^sup -1^) to substantial in northern quolls (0.100°C ºC^sup -1^) and chuditch (0.146°C ºC^sup -1^), reflecting body mass and environment. Basal metabolic rate was higher for eastern quolls (0.662 ± 0.033 ml O^sub 2^ g^sup -1^ h^sup -1^), presumably reflecting their naturally cool environment. Respiratory ventilation closely matched metabolic demand, except at high ambient temperatures where quolls hyperventilated to facilitate evaporative heat loss; tiger and eastern quolls also salivated. A higher evaporative water loss for eastern quolls (1.43 ± 0.212 mg H^sub 2^O g^sup -1^ h^sup -1^) presumably reflects their more mesic distribution. The point of relative water economy was low for tiger (-1.3°C), eastern (-12.5°C) and northern (+3.3) quolls, and highest for the chuditch (+22.6°C). We suggest that these differences in water economy reflect lower expired air temperatures and hence lower respiratory evaporative water loss for the arid-zone chuditch relative to tropical and mesic quolls

A study to assess changes in myocardial perfusion after treatment with spinal cord stimulation and percutaneous myocardial laser revascularisation; data from a randomised trial

<p>Abstract</p> <p>Background</p> <p>Spinal cord stimulation (SCS) and percutaneous myocardial laser revascularisation (PMR) are treatment modalities used to treat refractory angina pectoris, with the major aim of such treatment being the relief of disabling symptoms. This study compared the change in myocardial perfusion following SCS and PMR treatment.</p> <p>Methods</p> <p>Subjects with Canadian Cardiovascular Society class 3/4 angina and reversible perfusion defects as assessed by single-photon emission computed tomographic myocardial perfusion scintigraphy were randomised to SCS (34) or PMR (34). 28 subjects in each group underwent repeat myocardial perfusion imaging 12 months post intervention. Visual scoring of perfusion images was performed using a 20-segment model and a scale of 0 to 4.</p> <p>Results</p> <p>The mean (standard deviation) baseline summed rest score (SRS) and stress scores (SSS) were 4.6 (5.7) and 13.6 (9.0) in the PMR group and 6.1 (7.4) and 16.8 (11.6) in the SCS group. At 12 months, SRS was 5.5 (6.0) and SSS 15.3 (11.3) in the PMR group and 6.9 (8.2) and 15.1 (10.9) in the SCS group. There was no significant difference between the two treatment groups adjusted for baseline (p = 1.0 for SRS, p = 0.29 for SSS).</p> <p>Conclusion</p> <p>There was no significant difference in myocardial perfusion one year post treatment with SCS or PMR.</p

Additional Thoughts on Rigor in Wildlife Science: Unappreciated Impediments

Traditionally, most scientists accepted reductionist and mechanistic approaches as the rigorous way to do science. Sells et al. (2018) recently raised the argument about reliability in wildlife science. Chamberlin (1890), Platt (1964), Romesburg (1981, 1991, 2009), and Williams (1997) were rightly referenced as very influential papers. My intention in this letter is not to refute the essence of the Sells et al. (2018) commentary but to add seldom addressed but important aspects that influence the attainment of rigor and certainty in wildlife studies. The elements of a rigorous approach (i.e., strong inference) as described by Platt (1964) included devising alternative hypotheses, devising ≥1 crucial experiments that will exclude ≥1 of the hypotheses, and carrying out the experiment to get a clean result. The process was then repeated using logical inductive trees (i.e., a continually bifurcated statement hypotheses approach) to obtain the essential cause for the effect. Platt (1964) agreed with Popper (1959) that science advanced only by disproof. He argued that this was a hard doctrine and leads to disputations between scientists, but that Chamberlin\u27s (1890) method of multiple working hypotheses helped to remove that difficulty. Platt (1964) emphasized inductive inference and crucial and critical experiments whereby alternate hypotheses are refuted. Romesburg (1981) explained that in wildlife biology, induction (reliable associations) and retroduction (developing hypotheses) were the basis for almost all wildlife research but were not sufficient. He proposed the hypothetical‐deductive (H‐D) method as a more reliable approach. Citing Harvey (1969), and Popper (1962), Romesburg (1981:294) explained that “Starting with the research hypothesis, usually obtained by retroduction, predictions are made about other classes of facts that should be true if the research hypothesis is actually true.” The hypothesis is then tested indirectly by using logic to deduce one or more test consequences (Romesburg 2014). Data are then collected in a statistical framework. Romesburg (1981) distinguished between a research hypothesis (i.e., a conjecture about some process) versus a statistical hypothesis (i.e., a conjecture about classes of facts encompassed by the process). Williams (1997) clearly explained the differences between necessary and sufficient causation and gave examples of the coherent logic both entailed. He summarized that the science endeavor included theory, hypotheses, predictions, observations, and comparison of predictions against data, and argued that inductive and deductive logic were required for testing hypotheses. Importantly, Williams (1997:1014) recognized that wildlife biology often involves simultaneous complementary explanatory factors, requiring “the framing of many scientifically interesting issues about cause and effect in terms of the relative contribution of multiple causal factors.” Over the years, many others have addressed the issue of rigor and reliability in the Journal of Wildlife Management (JWM) and the Wildlife Society Bulletin (WSB) either directly (McNab 1983, Eberhardt 1988, Anderson 2001) or indirectly (Steidl et al. 1997, Guthery et al. 2001). This is not a complete list and is limited primarily to JWM and WSB but gives an idea of the wide interest in achieving reliable results from wildlife studies

Dirty Bomb Fallout

At present, there is a significant need to develop decontamination agents that can be used effectively after detonation of a radiological dispersal device (RDD) in an urban environment. There is also a need for the development of reproducible test surfaces to be used to determine the efficacy of the agent being developed. Researchers at Lawrence Livermore National Laboratory (LLNL), under the auspices of the US Department of Energy (DoE), conducted a field study to evaluate the deposition of an explosively dispersed radionuclide surrogate (CsCl) on grime-bearing and non-grime-bearing urban surfaces. The goal was to investigate the preparation and contamination of urban surfaces that closely mimic what one would expect to encounter following the detonation of an RDD. Migration of Cs into concrete surfaces was investigated in detail. Many non-proliferation, security and response organizations that have modeled RDD scenarios use cesium-137, as well as cobalt-60, strontium-90, americium-241 as the most likely RDD agents. Cesium-137 is an isotope of concern for possible use in an RDD due to its potential availability resulting from its widespread legitimate use in construction, geotechnical and medical industrial devices. In some Cs-containing instruments the Cesium-137 is present as the highly dispersible and water soluble salt, cesium chloride (CsCl). In this form Cs is able to rapidly disperse in the environment, as witnessed in the 1987 Goiania accident in Brazil, when inadvertent dispersal of a radiotherapy source resulted in fatalities and injuries

Convergence of dynamic vegetation net productivity responses to precipitation variability from 10 years of MODIS EVI

According to Global Climate Models (GCMs) the occurrence of extreme events of precipitation will be more frequent in the future. Therefore, important challenges arise regarding climate variability, which are mainly related to the understanding of ecosystem responses to changes in precipitation patterns. Previous studies have found that Above-ground Net Primary Productivity (ANPP) was positively related to increases in annual precipitation and this relation may converge across biomes during dry years. One challenge in studying this ecosystem response at the continental scale is the lack of ANPP field measurements over extended areas. In this study, the MODIS EVI was utilized as a surrogate for ANPP and combined with precipitation datasets from twelve different experimental sites across the United States over a 10-year period. Results from this analysis confirmed that integrated-EVI for different biomes converged toward common precipitation use efficiency during water-limited periods and may be a viable surrogate for ANPP measurements for further ecological research

Observation of two new Ξb−\Xi_b^- baryon resonances

Two structures are observed close to the kinematic threshold in the $\Xi_b^0 \pi^-$ mass spectrum in a sample of proton-proton collision data, corresponding to an integrated luminosity of 3.0 fb$^{-1}$ recorded by the LHCb experiment. In the quark model, two baryonic resonances with quark content $bds$ are expected in this mass region: the spin-parity $J^P = \frac{1}{2}^+$ and $J^P=\frac{3}{2}^+$ states, denoted $\Xi_b^{\prime -}$ and $\Xi_b^{*-}$. Interpreting the structures as these resonances, we measure the mass differences and the width of the heavier state to be $m(\Xi_b^{\prime -}) - m(\Xi_b^0) - m(\pi^{-}) = 3.653 \pm 0.018 \pm 0.006$ MeV$/c^2$, $m(\Xi_b^{*-}) - m(\Xi_b^0) - m(\pi^{-}) = 23.96 \pm 0.12 \pm 0.06$ MeV$/c^2$, $\Gamma(\Xi_b^{*-}) = 1.65 \pm 0.31 \pm 0.10$ MeV, where the first and second uncertainties are statistical and systematic, respectively. The width of the lighter state is consistent with zero, and we place an upper limit of $\Gamma(\Xi_b^{\prime -}) < 0.08$ MeV at 95% confidence level. Relative production rates of these states are also reported.Comment: 17 pages, 2 figure