Engineering the Cambrian explosion: the earliest bioturbators as ecosystem engineers

By applying modern biological criteria to trace fossil types and assessing burrow morphology, complexity, depth, potential burrow function and the likelihood of bioirrigation, we assign ecosystem engineering impact (EEI) values to the key ichnotaxa in the lowermost Cambrian (Fortunian). Surface traces such as Monomorphichnus have minimal impact on sediment properties and have very low EEI values; quasi-infaunal traces of organisms that were surficial modifiers or biodiffusors, such as Planolites, have moderate EEI values; and deeper infaunal, gallery biodiffusive or upward-conveying/downward-conveying traces, such as Teichichnus and Gyrolithes, have the highest EEI values. The key Cambrian ichnotaxon Treptichnus pedum has a moderate to high EEI value, depending on its functional interpretation. Most of the major functional groups of modern bioturbators are found to have evolved during the earliest Cambrian, including burrow types that are highly likely to have been bioirrigated. In fine-grained (or microbially bound) sedimentary environments, trace-makers of bioirrigated burrows would have had a particularly significant impact, generating advective fluid flow within the sediment for the first time, in marked contrast with the otherwise diffusive porewater systems of the Proterozoic. This innovation is likely to have created significant ecospace and engineered fundamentally new infaunal environments for macrobiotic and microbiotic organisms alike

Confirming the metazoan character of a 565Ma trace-fossil assemblage from Mistaken Point, Newfoundland

Surface locomotory trace fossils from the Mistaken Point Formation of Newfoundland, dated at ∼ 565 Ma, suggest that organisms capable of controlled locomotion and possessing muscular tissue may have existed among Avalonian Ediacaran macrofossil assemblages. Here we describe the Mistaken Point trace-fossil assemblage in full, discuss its stratigraphic context within the Mistaken Point Formation, and explore the competing hypotheses for the formation of the traces. We find that the trace fossils, preserved within a turbidite succession in a deep-marine depositional environment, are not attributable to abiogenic structures, to Ediacaran tubular or filamentous body fossils, to rangeomorph stems, or to a host of late Ediacaran and early Phanerozoic ichnofossils. Specimens within the assemblage show some similarities to the ichnogenera Helminthoidichnites and Archaeonassa, but discrepancies in certain aspects of their structure mean that we do not formally attribute them to these ichnotaxa at this time. The Mistaken Point ichnofossils possess morphological characteristics indicative of formation by an organism with a round base. Comparison with traces formed by modern organisms of such character appears to rule out formation by protistan, echinoderm, or annelid styles of movement, but is consistent with organisms moving via muscular controlled locomotion in a similar way to some modern mollusks and actinian cnidarians. We suggest therefore that the Mistaken Point trace-fossil assemblage reveals the presence of muscular metazoans in late Ediacaran deep-marine ecosystems. Such organisms cannot yet be attributed to specific phyla, but their inferred locomotory mechanisms share closest similarities with those utilized by extant actinians

Union renewal in historical perspective

This article revisits contemporary union renewal/revival debates through comparison with the late 1930s resurgence of trade unionism in the UK’s engineering industry. It is argued that the 1930s union renewal arose from more favourable contextual conditions than those currently obtaining. It was led by political activists, with better-articulated organisation and greater resonance in the working class than their contemporary counterparts, and who were assisted by state policy and pro-worker forces. Conclusions are drawn in relation to current debates

Post-fossilization processes and their implications for understanding Ediacaran macrofossil assemblages

Fossil assemblages from Newfoundland's Avalon Peninsula preserve diverse examples of the enigmatic Ediacaran macrobiota, offering some of the earliest evidence for large and complex multicellular life. These fossils are exposed on extensive coastal bedding planes in extraordinary abundances, permitting palaeoecological studies based on census data from spatially extensive palaeocommunities. Such studies have been used to constrain the reproductive strategy and phylogenetic placement of Ediacaran organisms. Geological mapping and stratigraphic correlation in the Mistaken Point Ecological Reserve reveal that some fossil-bearing surfaces can be tracked over distances of several kilometres. These laterally extensive surfaces reveal that the modern processes by which the sediment overlying a fossil surface is removed may impose important controls on the observed composition of fossil assemblages. Weathering and erosion – along with factors associated with tectonics, metamorphism and discovery – are here grouped as ‘post-fossilization processes’ and introduce biases that are often not explicitly accounted for in palaeoecological studies. Specifically, post-fossilization processes may differentially influence the preservational fidelity of individual specimens on a given surface and generate features that could be mistaken for original morphological characters. We therefore recommend that post-fossilization processes must be considered when undertaking palaeoecological studies in Ediacaran successions in Newfoundland and, potentially, elsewhere

The arrangement of possible muscle fibres in the Ediacaran taxon <i>Haootia quadriformis</i>

Haootia quadriformis from Newfoundland, Canada, is one of the most unusual impressions of a soft-bodied macro-organism yet described from the late Ediacaran Period. Interpreted as a metazoan of cnidarian grade, the body impression of H. quadriformis possesses features interpreted as fibrous structures that represent possible evidence for muscular tissue. Evidence both in support of and against a relationship between H. quadriformis and the Staurozoa, one of the cnidarian groups to which Haootia was compared in Liu et al., is outlined by Miranda et al.. Our intention in our original paper was to illustrate the staurozoan body plan for comparative purposes, rather than suggest homology or direct ancestry. Nevertheless, fresh insights from workers with expertise in the biology of extant cnidarians are welcomed

Fifty years of spellchecking

A short history of spellchecking from the late 1950s to the present day, describing its development through dictionary lookup, affix stripping, correction, confusion sets, and edit distance to the use of gigantic databases

Effects of drive amplitude on continuous jet break-up

We develop a one-dimensional model of jet breakup in continuous inkjet printing to explore the nonlinear behavior caused by finite-amplitude modulations in the driving velocity, where jet stability deviates from classic (linear) “Rayleigh” behavior. At low driving amplitudes and high Weber numbers, the spatial instability produces drops that pinch-off downstream of the connecting filament, leading to the production of small satellite droplets between the main drops. On the other hand, we identify a range of driving amplitudes where pinching becomes “inverted,” occurring upstream of the filament connecting the main drops, rather than downstream. This inverted breakup is preferable in printing, as it increases the likelihood of satellite drops merging with the main drops. We find that this behavior can be controlled by the addition of a second harmonic to the driving signal. This model is in quantitative agreement with a full axisymmetric simulation, which incorporates nozzle geometry

Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue

Fenretinide (FEN) is a synthetic retinoid that inhibits obesity and insulin resistance in high-fat diet (HFD)-fed mice and completely prevents 3T3-L1 pre-adipocyte differentiation. The aim of this study was to determine the mechanism(s) of FEN action in 3T3-L1 adipocytes and in mice. We used the 3T3-L1 model of adipogenesis, fully differentiated 3T3-L1 adipocytes and adipose tissue from HFD-induced obese mice to investigate the mechanisms of FEN action. We measured expression of adipogenic and retinoid genes by qPCR and activation of nutrient-signalling pathways by western blotting. Global lipid and metabolite analysis was performed and specific ceramide lipid species measured by liquid chromatography-mass spectrometry. We provide direct evidence that FEN inhibits 3T3-L1 adipogenesis via RA-receptor (RAR)-dependent signaling. However, RARα antagonism did not prevent FEN-induced decreases in lipid levels in mature 3T3-L1 adipocytes, suggesting an RAR-independent mechanism. Lipidomics analysis revealed that FEN increased dihydroceramide lipid species 5- to 16-fold in adipocytes, indicating an inhibition of the final step of ceramide biosynthesis. A similar blockade in adipose tissue from FEN-treated obese mice was associated with a complete normalisation of impaired mitochondrial β-oxidation and tricarboxylic acid cycle flux. The FEN catabolite, 4-oxo-N-(4-hydroxyphenyl)retinamide (4-OXO), also decreased lipid accumulation without affecting adipogenesis. FEN and 4-OXO (but not RA) treatment additionally led to the activation of p38-MAPK, peIF2α and autophagy markers in adipocytes. Overall our data reveals FEN utilises both RAR-dependent and -independent pathways to regulate adipocyte biology, both of which may be required for FEN to prevent obesity and insulin resistance in vivo

British trade unions and the academics: the case of Unionlearn

Unionlearn and union learning representatives were developed by the British TUC to match workers with education and training opportunities, strengthen the economy, foster market inclusion and facilitate social mobility. Their contribution to union revitalisation was emphasised. This article questions whether, with unions confronting global crisis, this is a necessary initiative. It stemmed from TUC failure to achieve policy goals, institutional needs, consequent acceptance of a lesser role, and the availability of state finance. Claims by academics that it provides influence over state policy and contributes to revitalisation remain inadequately evidenced. Union resurgence is not immanent. The way forward is through adversarial grassroots organising and socialist education, not through retooling capital, improving members’ marketability and partnership with a hostile state