348 research outputs found
A Test of Cosmological Models using high-z Measurements of H(z)
The recently constructed Hubble diagram using a combined sample of SNLS and
SDSS-II Type Ia SNe, and an application of the Alcock-Paczynski (AP) test using
model-independent Baryon Acoustic Oscillation data, have suggested that the
principal constraint underlying the cosmic expansion is the total
equation-of-state of the cosmic fluid, rather than that of its dark energy.
These studies have focused on the critical redshift range (0 < z < 2) within
which the transition from decelerated to accelerated expansion is thought to
have occurred, and they suggest that the cosmic fluid has zero active mass,
consistent with a constant expansion rate. The evident impact of this
conclusion on cosmological theory calls for an independent confirmation. In
this paper, we carry out this crucial one-on-one comparison between the R_h=ct
Universe (an FRW cosmology with zero active mass) and wCDM/LCDM, using the
latest high-z measurements of H(z). Whereas the Type Ia SNe yield the
integrated luminosity distance, while the AP diagnostic tests the geometry of
the Universe, the Hubble parameter directly samples the expansion rate itself.
We find that the model-independent cosmic chronometer data prefer R_h}=ct over
wCDM/LCDM with a BIC likelihood of ~95% versus only ~5%, in strong support of
the earlier SNeIa and AP results. This contrasts with a recent analysis of H(z)
data based solely on BAO measurements which, however, strongly depend on the
assumed cosmology. We discuss why the latter approach is inappropriate for
model comparisons, and emphasize again the need for truly model-independent
observations to be used in cosmological tests.Comment: 22 pages, 1 figure, 1 table. Accepted for publication in the
Astronomical Journa
Olfactory Thresholds of the U.S. Population of Home-Dwelling Older Adults: Development and Validation of a Short, Reliable Measure
Current methods of olfactory sensitivity testing are logistically challenging and therefore infeasible for use in in-home surveys and other field settings. We developed a fast, easy and reliable method of assessing olfactory thresholds, and used it in the first study of olfactory sensitivity in a nationally representative sample of U.S. home-dwelling older adults. We validated our method via computer simulation together with a model estimated from 590 normosmics. Simulated subjects were assigned n-butanol thresholds drawn from the estimated normosmic distribution and based on these and the model, we simulated administration of both the staircase and constant stimuli methods. Our results replicate both the correlation between the two methods and their reliability as previously reported by studies using human subjects. Further simulations evaluated the reliability of different constant stimuli protocols, varying both the range of dilutions and number of stimuli (6–16). Six appropriately chosen dilutions were sufficient for good reliability (0.67) in normosmic subjects. Finally, we applied our method to design a 5-minute, in-home assessment of older adults (National Social Life, Health and Aging Project, or NSHAP), which had comparable reliability (0.56), despite many subjects having estimated thresholds above the strongest dilution. Thus, testing with a fast, 6-item constant stimuli protocol is informative, and permits olfactory testing in previously inaccessible research settings
Reflection Spectroscopy of the Black Hole Binary XTE J1752-223 in its Long-Stable Hard State
We present a detailed spectral analysis of the Black Hole Binary XTE
J1752-223 in the hard state of its 2009 outburst. Regular monitoring of this
source by RXTE provided high signal-to-noise spectra along the outburst rise
and decay. During one full month this source stalled at 30\% of its peak
count rate at a constant hardness and intensity. By combining all the data in
this exceptionally-stable hard state, we obtained an aggregate PCA spectrum
(3-45 keV) with 100 million counts, and a corresponding HEXTE spectrum (20-140
keV) with 5.8 million counts. Implementing a version of our reflection code
with a physical model for Comptonization, we obtain tight constraints on
important physical parameters for this system. In particular, the inner
accretion disk is measured very close in, at .
Assuming , we find a relatively high black hole
spin (). Imposing a lamppost geometry, we obtain a low
inclination ( deg), which agrees with the upper limit found in the
radio ( deg). However, we note that this model cannot be statistically
distinguished from a non-lamppost model with free emissivity index, for which
the inclination is markedly higher. Additionally, we find a relatively cool
corona ( keV), and large iron abundance ( solar). We further
find that properly accounting for Comptonization of the reflection emission
improves the fit significantly and causes an otherwise low reflection fraction
() to increase by an order of magnitude, in line with geometrical
expectations for a lamppost corona. We compare these results with similar
investigations reported for GX 339-4 in its bright hard state.Comment: Accepted for publication in ApJ. 11 pages, 7 figure
Anterior cingulate gamma-aminobutyric acid concentrations and electroconvulsive therapy
Objective
The anticonvulsant hypothesis posits that ECT’s mechanism of action is related to enhancement of endogenous anticonvulsant brain mechanisms. Results of prior studies investigating the role of the inhibitory neurotransmitter gamma‐aminobutyric acid (“GABA+”, GABA and coedited macromolecules) in the pathophysiology and treatment of depression remain inconclusive. The aim of our study was to investigate treatment‐responsive changes of GABA+ in subjects with a depressive episode receiving electroconvulsive therapy (ECT).
Methods
In total, 41 depressed subjects (DEP) and 35 healthy controls (HC) were recruited at two independent sites in Norway and the USA. MEGA‐PRESS was used for investigation of GABA+ in the anterior cingulate cortex. We assessed longitudinal and cross‐sectional differences between DEP and HC, as well as the relationship between GABA+ change and change in depression severity and number of ECTs. We also assessed longitudinal differences in cognitive performance and GABA+ levels.
Results
Depressive episode did not show a difference in GABA+ relative to HC (t71 = −0.36, p = .72) or in longitudinal analysis (t36 = 0.97, p = .34). Remitters and nonremitters did not show longitudinal (t36 = 1.12, p = .27) or cross‐sectional differences in GABA+. GABA+ levels were not related to changes in antidepressant response (t35 = 1.12, p = .27) or treatment number (t36 = 0.05, p = .96). An association between cognitive performance and GABA+ levels was found in DEP that completed cognitive effortful testing (t18 = 2.4, p = .03).
Conclusion
Our results failed to support GABA as a marker for depression and abnormal mood state and provide no support for the anticonvulsant hypothesis of ECT. ECT‐induced change in GABA concentrations may be related to change in cognitive function.publishedVersio
MESSENGER Observations of Large Flux Transfer Events at Mercury
Six flux transfer events (FTEs) were encountered during MESSENGER's first two flybys of Mercury (M1 and M2). For M1 the interplanetary magnetic field (IMF) was predominantly northward and four FTEs with durations of 1 to 6 s were observed in the magnetosheath following southward IMF turnings. The IMF was steadily southward during M2, and an FTE 4 s in duration was observed just inside the dawn magnetopause followed approx. 32 s later by a 7 s FTE in the magnetosheath. Flux rope models were fit to the magnetic field data to determine FTE dimensions and flux content. The largest FTE observed by MESSENGER had a diameter of approx. 1 R(sub M) (where R(sub M) is Mercury s radius), and its open magnetic field increased the fraction of the surface exposed to the solar wind by 10 - 20 percent and contributed up to approx. 30 kV to the cross-magnetospheric electric potential
Solar wind forcing at Mercury: WSA‐ENLIL model results
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97237/1/jgra50070.pd
Mercury's Weather-Beaten Surface: Understanding Mercury in the Context of Lunar and Asteroid Space Weathering Studies
Understanding the composition of Mercury's crust is key to comprehending the formation of the planet. The regolith, derived from the crustal bedrock, has been altered via a set of space weathering processes. These processes are the same set of mechanisms that work to form Mercury's exosphere, and are moderated by the local space environment and the presence of an intrinsic planetary magnetic field. The alterations need to be understood in order to determine the initial crustal compositions. The complex interrelationships between Mercury's exospheric processes, the space environment, and surface composition are examined and reviewed. The processes are examined in the context of our understanding of these same processes on the lunar and asteroid regoliths. Keywords: Mercury (planet) Space weathering Surface processes Exosphere Surface composition Space environment
Solar wind forcing at Mercury: WSA-ENLIL model results
Analysis and interpretation of observations from the MESSENGER spacecraft in orbit about Mercury require knowledge of solar wind “forcing” parameters. We have utilized the Wang-Sheeley-Arge (WSA)-ENLIL solar wind modeling tool in order to calculate the values of interplanetary magnetic field (IMF) strength (B), solar wind velocity (V) and density (n), ram pressure (~nV2), cross-magnetosphere electric field (V × B), Alfvén Mach number (MA), and other derived quantities of relevance for solar wind-magnetosphere interactions. We have compared upstream MESSENGER IMF and solar wind measurements to see how well the ENLIL model results compare. Such parameters as solar wind dynamic pressure are key for determining the Mercury magnetopause standoff distance, for example. We also use the relatively high-time-resolution B-field data from MESSENGER to estimate the strength of the product of the solar wind speed and southward IMF strength (Bs) at Mercury. This product VBs is the electric field that drives many magnetospheric dynamical processes and can be compared with the occurrence of energetic particle bursts within the Mercury magnetosphere. This quantity also serves as input to the global magnetohydrodynamic and kinetic magnetosphere models that are being used to explore magnetospheric and exospheric processes at Mercury. Moreover, this modeling can help assess near-real-time magnetospheric behavior for MESSENGER or other mission analysis and/or ground-based observational campaigns. We demonstrate that this solar wind forcing tool is a crucial step toward bringing heliospheric science expertise to bear on planetary exploration programs
Tomato: a crop species amenable to improvement by cellular and molecular methods
Tomato is a crop plant with a relatively small DNA content per haploid genome and a well developed genetics. Plant regeneration from explants and protoplasts is feasable which led to the development of efficient transformation procedures.
In view of the current data, the isolation of useful mutants at the cellular level probably will be of limited value in the genetic improvement of tomato. Protoplast fusion may lead to novel combinations of organelle and nuclear DNA (cybrids), whereas this technique also provides a means of introducing genetic information from alien species into tomato. Important developments have come from molecular approaches. Following the construction of an RFLP map, these RFLP markers can be used in tomato to tag quantitative traits bred in from related species. Both RFLP's and transposons are in the process of being used to clone desired genes for which no gene products are known. Cloned genes can be introduced and potentially improve specific properties of tomato especially those controlled by single genes. Recent results suggest that, in principle, phenotypic mutants can be created for cloned and characterized genes and will prove their value in further improving the cultivated tomato.
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