574 research outputs found
12. The Internal Learning System – A Tool for Tracking and Enhancing Empowerment Outcomes and Wider Social Impacts of Microfinance
Participatory Learning for Women's Empowerment in Micro?Finance Programmes: Negotiating Complexity, Conflict and Change
summary Micro?finance programmes for women are currently promoted not only as a strategy for poverty alleviation but also for women's empowerment. However, the complexity of empowerment itself and interlinkages with policy make conventional research methodologies extremely lengthy and costly. This article proposes frameworks and participatory methodologies for integrating empowerment concerns into ongoing programme learning. These would themselves be a contribution to empowerment. First, programme staff would be given a more representative and reliable exposure to the priorities and problems of programme participants. Second, it would develop networks and a forum for discussion between women themselves on issues relevant to their interests and integrated into programme decision?making. The quantitative and qualitative information obtained by programmes and clients on an ongoing basis would be directly and immediately available to inform policy decisions and enable independent outsider research to be cost?effectively targeted to issues where it is really needed for policy development
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Angiotensin {II}-induced redox-sensitive {SGLT}1 and 2 expression promotes high glucose-induced endothelial cell senescence
High glucose (HG)-induced endothelial senescence and dysfunction contribute to the increased cardiovascular risk in diabetes. Empagliflozin, a selective sodium glucose co-transporter2 (SGLT2) inhibitor, reduced the risk of cardiovascular mortality in type 2 diabetic patients but the protective mechanism remains unclear. This study examines the role of SGLT2 in HG-induced endothelial senescence and dysfunction. Porcine coronary artery cultured endothelial cells (ECs) or segments were exposed to HG (25 mmol/L) before determination of senescence-associated beta-galactosidase activity, protein level by Western blot and immunofluorescence staining, mRNA by RT-PCR, nitric oxide (NO) by electron paramagnetic resonance, oxidative stress using dihydroethidium and glucose uptake using 2-NBD-glucose. HG increased ECs senescence markers and oxidative stress, down-regulated eNOS expression and NO formation, and induced the expression of VCAM-1, tissue factor, and the local angiotensin system, all these effects were prevented by empagliflozin. Empagliflozin and LX-4211 (dual SGLT1/2 inhibitor) reduced glucose uptake stimulated by HG and H2O2 in ECs. HG increased SGLT1 and 2 protein levels in cultured ECs and native endothelium. Inhibition of the angiotensin system prevented HG-induced ECs senescence and SGLT1 and 2 expression. Thus, HG-induced ECs ageing is driven by the local angiotensin system via the redox-sensitive up-regulation of SGLT1 and 2, and, in turn, enhanced glucotoxicity
Public participation in the process of EIA intentions of wind power plants in the Czech Republic
Public participation in decision-making process is an important function of the process called Environmental Impact Assessment (EIA). The respect for the public right in the participation of environmental impact assessment and the right to information are generally controlled by non-governmental organizations (NGOs) in cooperation with the Ministry of Environment. The support of public is provided in the cases in which queried entity tries not to give the requested information in the appropriate range. NGOs do not follow how the public is involved in the EIA process, and how the comments are relevant or incorporated and whether the final standpoint is influenced. This standpoint is not monitored by Czech Statistical Office. The article deals with the involvement of the general public in the EIA process of wind power plants in the Czech Republic. In selected regions (Moravskoslezský, Olomoucký, Ústecký and Jihomoravský), not only the quantity but also the relevance of the comments in relation to the outcome of the process are evaluated. The own typology groups of the public (individuals, petitions, self-government etc.) and also applying comments (noise, nature protection, administrative mistakes etc.) were used for the evaluation. All intentions obtained concurring standpoints in the case of zero or low interest of the public.O
Engaging fringe stakeholders in business and society research: applying visual participatory research methods
Business and society (B&S) researchers, as well as practitioners, have been critiqued for ignoring those with less voice and power (e.g. women, non-literate or indigenous peoples) often referred to as ‘fringe stakeholders’. Existing methods used in B&S research often fail to address issues of meaningful participation, voice and power, especially in developing countries. In this article we stress the utility of visual participatory research (VPR) methods in B&S research to fill this gap. Through a case study on engaging Ghanaian cocoa farmers on gender inequality issues we explore how VPR methods may be used by researchers to achieve more inclusive, and thus more credible, stakeholder research that can improve decision-making within businesses. Furthermore, we argue that ingrained social and environmental problems tackled by B&S research and the unique context in which they occur may open up new opportunities to develop participatory visual methods for social change
Programme Impact Assessment in Micro?Finance: The Need for Analysis of Real Markets
summary Impact assessment in micro?finance has focused on the impact of services on users and the ability of the organisation delivering those services to sustain its operations into the future. However, a focus on building organisations capable of long?term provision assumes that they will have a positive impact on the efficiency of the financial market. This is an assumption which impact assessment should also test but which has so far been neglected. Moreover, the search for a framework within which to undertake such an assessment must incorporate the complex array of social and political, as well as economic, relationships which financial markets embody. A fourfold analytical approach is proposed which can incorporate gender relations and which focuses on state involvement, market organisation, market structure and social embeddedness
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