257 research outputs found

    Defect mediated melting and the breaking of quantum double symmetries

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    In this paper, we apply the method of breaking quantum double symmetries to some cases of defect mediated melting. The formalism allows for a systematic classification of possible defect condensates and the subsequent confinement and/or liberation of other degrees of freedom. We also show that the breaking of a double symmetry may well involve a (partial) restoration of an original symmetry. A detailed analysis of a number of simple but representative examples is given, where we focus on systems with global internal and external (space) symmetries. We start by rephrasing some of the well known cases involving an Abelian defect condensate, such as the Kosterlitz-Thouless transition and one-dimensional melting, in our language. Then we proceed to the non-Abelian case of a hexagonal crystal, where the hexatic phase is realized if translational defects condense in a particular rotationally invariant state. Other conceivable phases are also described in our framework.Comment: 10 pages, 4 figures, updated reference

    Inner speech sustains predictable task switching: direct evidence in adults

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    It has been proposed that inner speech supports task selection in task-switching studies, especially when the need for endogenous control is increased. This has been established through the suppression of inner speech in cognitive-flexibility tasks that leads to poorer performance. The aim of this study is to quantify the role of inner speech in a flexibility task by using surface laryngeal electromyography, which, contrary to previous studies, enables participants to freely verbalise the tasks. We manipulated endogenous and exogenous flexibility in a mathematical switching task paradigm. Experiment 1 shows that inner speech acts as a support for switching and is recruited more often when the tasks are of an endogenous type. The main result of Experiment 2 that language is recruited more for the mixing cost than for the switch cost (regardless of the endogenous factor) extends past findings obtained through articulatory suppression

    French translation and validation of the Jefferson Scale of Empathy - Health Professions Student version

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    Background: Background: Jefferson Scale of Empathy is one of the most widely used tools worldwide to assess empathy. The extended version for Health Professions Students (JSE HPS) has not yet been translated into French. Objective: The aim of our study was to translate the JSE HPS into French and assess the psychometric properties of this new version (JSE HPS Fr). Methods: The JSE HPS was translated according to international recommendations. The main psychometric qualities (test-retest reliability, internal consistency, floor and ceiling effects and construct validity) were studied in a sample of physiotherapy students. Participants provided general information (age, gender, year of study) and completed the JSE HPS Fr and the Questionnaire of Cognitive and Affective Empathy (QCAE). Participants were also asked to complete the JSE-HPS-Fr again one week later to assess its test-retest reliability. Results: 408 students (161 males and 247 females; mean age: 21.3 years) participated. The JSE HPS Fr demonstrated good test-retest reliability for the total score (ICC=0.81) and good internal consistency (α Cronbach: 0.79). The JSE HPS also showed good convergent validity with the QCAE questionnaire (r=0.41, p<0.05). No floor or ceiling effects were observed. Conclusions: The results indicate that the JSE HPS Fr is a valid and reliable tool to assess the level of empathy of French-speaking physiotherapy students

    GRIDKIT: Pluggable overlay networks for Grid computing

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    A `second generation' approach to the provision of Grid middleware is now emerging which is built on service-oriented architecture and web services standards and technologies. However, advanced Grid applications have significant demands that are not addressed by present-day web services platforms. As one prime example, current platforms do not support the rich diversity of communication `interaction types' that are demanded by advanced applications (e.g. publish-subscribe, media streaming, peer-to-peer interaction). In the paper we describe the Gridkit middleware which augments the basic service-oriented architecture to address this particular deficiency. We particularly focus on the communications infrastructure support required to support multiple interaction types in a unified, principled and extensible manner-which we present in terms of the novel concept of pluggable overlay networks

    On Form Factors in nested Bethe Ansatz systems

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    We investigate form factors of local operators in the multi-component Quantum Non-linear Schr\"odinger model, a prototype theory solvable by the so-called nested Bethe Ansatz. We determine the analytic properties of the infinite volume form factors using the coordinate Bethe Ansatz solution and we establish a connection with the finite volume matrix elements. In the two-component models we derive a set of recursion relations for the "magnonic form factors", which are the matrix elements on the nested Bethe Ansatz states. In certain simple cases (involving states with only one spin-impurity) we obtain explicit solutions for the recursion relations.Comment: 34 pages, v2 (minor modifications

    Ultra-cold Polarized Fermi Gases

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    Recent experiments with ultra-cold atoms have demonstrated the possibility of realizing experimentally fermionic superfluids with imbalanced spin populations. We discuss how these developments have shed a new light on a half- century old open problem in condensed matter physics, and raised new interrogations of their own.Comment: 27 pages; 8 figures; Published in Report in Rep. Prog. Phys. 73 112401 (2010

    Liver Proteomic Response To Hypertriglyceridemia In Human-apolipoprotein C-iii Transgenic Mice At Cellular And Mitochondrial Compartment Levels

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    Background: Hypertriglyceridemia (HTG) is defined as a triglyceride (TG) plasma level exceeding 150 mg/dl and is tightly associated with atherosclerosis, metabolic syndrome, obesity, diabetes and acute pancreatitis. The present study was undertaken to investigate the mitochondrial, sub-mitochondrial and cellular proteomic impact of hypertriglyceridemia in the hepatocytes of hypertriglyceridemic transgenic mice (overexpressing the human apolipoproteinC-III). Methods. Quantitative proteomics (2D-DIGE) analysis was carried out on both "low-expressor" (LE) and "high- expressor" (HE) mice, respectively exhibiting moderate and severe HTG, to characterize the effect of the TG plasma level on the proteomic response. Results: The mitoproteome analysis has revealed a large-scale phenomenon in transgenic mice, i.e. a general down-regulation of matricial proteins and up-regulation of inner membrane proteins. These data also demonstrate that the magnitude of proteomic changes strongly depends on the TG plasma level. Our different analyses indicate that, in HE mice, the capacity of several metabolic pathways is altered to promote the availability of acetyl-CoA, glycerol-3-phosphate, ATP and NADPH for TG de novo biosynthesis. The up-regulation of several cytosolic ROS detoxifying enzymes has also been observed, suggesting that the cytoplasm of HTG mice is subjected to oxidative stress. Moreover, our results suggest that iron over-accumulation takes place in the cytosol of HE mice hepatocytes and may contribute to enhance oxidative stress and to promote cellular proliferation. Conclusions: These results indicate that the metabolic response to HTG in human apolipoprotein C-III overexpressing mice may support a high TG production rate and that the cytosol of hepatocytes is subjected to an important oxidative stress, probably as a result of FFA over-accumulation, iron overload and enhanced activity of some ROS-producing catabolic enzymes. © 2014 Ehx et al.; licensee BioMed Central Ltd.131Grundy, S.M., Brewer Jr., H.B., Cleeman, J.I., Smith Jr., S.C., Lenfant, C., Definition of Metabolic Syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition (2004) Circulation, 109 (3), pp. 433-438. , DOI 10.1161/01.CIR.0000111245.75752.C6Reid, A.E., Nonalcoholic steatohepatitis (2001) Gastroenterology, 121 (3), pp. 710-723Toskes, P.P., Hyperlipidemic pancreatitis (1990) Gastroenterol Clin North Am, 19, pp. 783-791Ginsberg, H.N., Ngoc-Anh, L., Goldberg, I.J., Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. 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insulin resistance (2011) Hepatology, 54, pp. 1650-1660Mathy, G., Navet, R., Gerkens, P., Leprince, P., De Pauw, E., Sluse-Goffart, C.M., Sluse, F.E., Douette, P., Saccharomyces cerevisiae mitoproteome plasticity in response to recombinant alternative ubiquinol oxidase (2006) Journal of Proteome Research, 5 (2), pp. 339-348. , DOI 10.1021/pr050346eKnowles, M.R., Cervino, S., Skynner, H.A., Hunt, S.P., De Felipe, C., Salim, K., Meneses-Lorente, G., Guest, P.C., Multiplex proteomic analysis by two-dimensional differential in-gel electrophoresis (2003) Proteomics, 3 (7), pp. 1162-1171. , DOI 10.1002/pmic.200300437Cardoso, A.R., Queliconi, B.B., Kowaltowski, A.J., Mitochondrial ion transport pathways: Role in metabolic diseases (2010) Biochim Biophys Acta, 1797, pp. 832-838Bonnard, C., Durand, A., Peyrol, S., Chanseaume, E., Chauvin, M.-A., Morio, B., Vidal, H., Rieusset, J., Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant 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    Colonist, 1889-02-15

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    The Colonist began on 6 March 1886, changing its name to The Newfoundland Colonist after 18 July 1891. Having printed local and international news Monday to Saturday for six years, the paper came to an abrupt end when its offices were destroyed in The Great Fire of 8 July 1892.Title variations recorded in Alternative Title, as needed

    ISGRI: the INTEGRAL Soft Gamma-Ray Imager

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    For the first time in the history of high energy astronomy, a large CdTe gamma-ray camera is operating in space. ISGRI is the low-energy camera of the IBIS telescope on board the INTEGRAL satellite. This paper details its design and its in-flight behavior and performances. Having a sensitive area of 2621 cm2^2 with a spatial resolution of 4.6 mm, a low threshold around 12 keV and an energy resolution of \sim 8% at 60 keV, ISGRI shows absolutely no signs of degradation after 9 months in orbit. All aspects of its in-flight behavior and scientific performance are fully nominal, and in particular the observed background level confirms the expected sensitivity of 1 milliCrab for a 106^6s observation.Comment: INTEGRAL A&A special issu

    Theory of excited state absorptions in phenylene-based π\pi-conjugated polymers

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    Within a rigid-band correlated electron model for oligomers of poly-(paraphenylene) (PPP) and poly-(paraphenylenevinylene) (PPV), we show that there exist two fundamentally different classes of two-photon Ag_g states in these systems to which photoinduced absorption (PA) can occur. At relatively lower energies there occur Ag_g states which are superpositions of one electron - one hole (1e--1h) and two electron -- two hole (2e--2h) excitations, that are both comprised of the highest delocalized valence band and the lowest delocalized conduction band states only. The dominant PA is to one specific member of this class of states (the mAg_g). In addition to the above class of Ag_g states, PA can also occur to a higher energy kAg_g state whose 2e--2h component is {\em different} and has significant contributions from excitations involving both delocalized and localized bands. Our calculated scaled energies of the mAg_g and the kAg_g agree reasonably well to the experimentally observed low and high energy PAs in PPV. The calculated relative intensities of the two PAs are also in qualitative agreement with experiment. In the case of ladder-type PPP and its oligomers, we predict from our theoretical work a new intense PA at an energy considerably lower than the region where PA have been observed currently. Based on earlier work that showed that efficient charge--carrier generation occurs upon excitation to odd--parity states that involve both delocalized and localized bands, we speculate that it is the characteristic electronic nature of the kAg_g that leads to charge generation subsequent to excitation to this state, as found experimentally.Comment: Revtex4 style, 2 figures inserted in the text, three tables, 10 page
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