Tracing dark energy with quasars

The nature of dark energy, driving the accelerated expansion of the Universe, is one of the most important issues in modern astrophysics. In order to understand this phenomenon, we need precise astrophysical probes of the universal expansion spanning wide redshift ranges. Quasars have recently emerged as such a probe, thanks to their high intrinsic luminosities and, most importantly, our ability to measure their luminosity distances independently of redshifts. Here we report our ongoing work on observational reverberation mapping using the time delay of the Mg II line, performed with the South African Large Telescope (SALT).Comment: 3 pages, 2 figures, submitted as PTA proceeding

Emission Line Galaxies and Active Galactic Nuclei in WINGS clusters

We present the analysis of the emission line galaxies members of 46 low redshift (0.04 < z < 0.07) clusters observed by WINGS (WIde-field Nearby Galaxy cluster Survey, Fasano et al. 2006). Emission line galaxies were identified following criteria that are meant to minimize biases against non-star forming galaxies and classified employing diagnostic diagrams. We have examined the emission line properties and frequencies of star forming galaxies, transition objects and active galactic nuclei (AGNs: LINERs and Seyferts), unclassified galaxies with emission lines, and quiescent galaxies with no detectable line emission. A deficit of emission line galaxies in the cluster environment is indicated by both a lower frequency with respect to control samples, and by a systematically lower Balmer emission line equivalent width and luminosity (up to one order of magnitude in equivalent width with respect to control samples for transition objects) that implies a lower amount of ionised gas per unit mass and a lower star formation rate if the source is classified as Hii region. A sizable population of transition objects and of low-luminosity LINERs (approx. 10 - 20% of all emission line galaxies) is detected among WINGS cluster galaxies. With respect to Hii sources they are a factor of approx. 1.5 more frequent than (or at least as frequent as) in control samples. Transition objects and LINERs in cluster are most affected in terms of line equivalent width by the environment and appear predominantly consistent with "retired" galaxies. Shock heating can be a possible gas excitation mechanism able to account for observed line ratios. Specific to the cluster environment, we suggest interaction between atomic and molecular gas and the intracluster medium as a possible physical cause of line-emitting shocks.Comment: Astronomy and Astrophysics, accepte

Radio Loud AGN in the Context of the Eigenvector 1 Parameter Space

We consider the properties of radio-loud (RL) AGN in the context of the Eigenvector 1 (E1) parameter space. RL sources show a restricted E1 parameter space occupation relative to the radio-quiet (RQ) majority. The Fanaroff-Riley II ``parent population'' of relatively un-boosted RL sources (median radio/optical flux ratio ~490) shows the most restricted occupation. RL sources have different broad line properties (and inferred black hole masses and Eddington ratios). FWHM H_beta for the broad line component in RL sources are at least twice as large as the RQ majority. The average broad FeII emission line strength is also about half that for RQ sources. Our sample suggests that the RL cutoff occurs near R_k=70 or logP(6cm)=32.0 ergs/s/Hz. Sources below this cutoff are RQ although we cannot rule out the existence of a distinct intermediate population. We show that the Doppler boosted core-dominated RL sources (median flux ratio ~1000) lie towards smaller FWHM(H_beta_bc) and stronger FeII in E1 as expected if the lines arise in an accretion disk. Our subsample of superluminal sources, with orientation inferred from the synchrotron self Compton model, reinforce this general E1 trend and allow us to estimate the role of source orientation in driving E1 domain occupation.Comment: 9 pages, 3 figures, accepted for publication in ApJ

The role of black hole mass in quasar radio activity

We use a homogeneous sample of about 300, 0.3 <~ z <~ 3, radio-loud quasars drawn from the FIRST and 2dF QSO surveys to investigate a possible dependence of radio activity on black-hole mass. By analyzing composite spectra for the populations of radio-quiet and radio-loud QSOs -- chosen to have the same redshift and luminosity distribution -- we find with high statistical significance that radio-loud quasars are on average associated with black holes of masses ~10^{8.6} M_sun, about twice as large as those measured for radio-quiet quasars (~10^{8.3} M_sun). We also find a clear dependence of black hole mass on optical luminosity of the form log (M_BH/M_sun)_{RL}= 8.57(\pm 0.06) - 0.27(\pm 0.06) (M_B + 24.5) and log (M_BH/M_sun)_{RQ}= 8.43(\pm 0.05) -0.32(\pm 0.06) (M_B + 24.5), respectively for the case of radio-loud and radio-quiet quasars. It is intriguing to note that these two trends run roughly parallel to each other, implying that radio-loud quasars are associated to black holes more massive than those producing the radio-quiet case at all sampled luminosities. On the other hand, in the case of radio-loud quasars, we find evidence for only a weak (if any) dependence of the black hole mass on radio power. The above findings seem to support the belief that there exists -- at a given optical luminosity -- a threshold black hole mass associated with the onset of significant radio activity such as that of radio-loud QSOs; however, once the activity is triggered, there appears to be very little connection between black hole mass and level of radio output.Comment: 10 pages, 10 figures, minor changes to match the accepted versio

The hybrid solution for the Fundamental Plane

By exploiting the database of early-type galaxies (ETGs) members of the WINGS survey of nearby clusters, we address here the long debated question of the origin and shape of the Fundamental Plane (FP). Our data suggest that different physical mechanisms concur in shaping and tilting the FP with respect to the virial plane (VP) expectation. In particular, an hybrid solution in which the structure of galaxies and their stellar population are the main contributors to the FP tilt seems to be favoured. We find that the bulk of the tilt should be attributed to structural non-homology, while stellar population effects play an important but less crucial role. Our data indicate that the differential FP tilt between the V and K-band is due to a sort of entanglement between structural and stellar population effects, for which the inward steepening of color profiles (V-K) tends to increase at increasing the stellar mass of ETGs. The same analysis applied to the ATLAS3D and SDSS data in common with WINGS (WSDSS throughout the paper) confirms our results, the only remarkable difference being the less important role of the stellar mass-to-light-ratio in determining the FP tilt. The ATLAS3D data also suggest that the tilt depends as well on the dark matter (DM) fraction and on the rotational contribution to the kinetic energy (Vrot/sigma). We show that the global properties of the FP can be understood in terms of the underlying correlation among mass, structure and stellar population of ETGs, for which, at increasing the stellar mass, ETGs become (on average) older and more centrally concentrated. Finally, we show that a Malmquist-like selection effect may mimic a differential evolution of the mass-to-light ratio for galaxies of different masses. This should be taken into account in the studies investigating the amount of the so called downsizing phenomenon.Comment: 22 pages, 17 figure

The Case for Optically-Thick High Velocity Broad Line Region Gas in Active Galactic Nuclei

A combined analysis of the profiles of the main broad quasar emission lines in both Hubble Space Telescope and optical spectra shows that while the profiles of the strong UV lines are quite similar, there is frequently a strong increase in the Ly-alpha/H-alpha ratio in the high-velocity gas. We show that the suggestion that the high velocity gas is optically-thin presents many problems. We show that the relative strengths of the high velocity wings arise naturally in an optically-thick BLR component. An optically-thick model successfully explains the equivalent widths of the lines, the Ly-alpha/H-alpha ratios and flatter Balmer decrements in the line wings, the strengths of CIII] and the lambda 1400 blend, and the strong variability of high-velocity, high-ionization lines (especially HeII and HeI).Comment: 34 pages in AASTeX, including 10 pages of figures. Submitted to Astrophysical Journa

Immunotherapy as a turning point in the treatment of acute myeloid leukemia

Acute myeloid leukemia (AML) is a malignant disease of hematopoietic precursors at the earliest stage of maturation, resulting in a clonalproliferation of myoblasts replacing normal hematopoiesis. AML represents one of the most common types of leukemia, mostly affecting elderly patients. To date, standard chemotherapy protocols are only effective in patients at low risk of relapse and therapy-related mortality. The average 5-year overall survival (OS) is approximately 28%. Allogeneic hematopoietic stem cell transplantation (HSCT) improves prognosis but is limited by donor availability, a relatively young age of patients, and absence of significant comorbidities. Moreover, it is associated with significant morbidity and mortality. However, increasing understanding of AML immunobiology is leading to the development of innovative therapeutic strategies. Immunotherapy is considered an attractive strategy for controlling and eliminating the disease. It can be a real breakthrough in the treatment of leukemia, especially in patients who are not eligible forintensive chemotherapy. In this review, we focused on the progress of immunotherapy in the field of AML by discussing monoclonal antibodies (mAbs), immune checkpoint inhibitors, chimeric antigen receptor T cells (CAR-T cells), and vaccine therapeutic choices

Black hole mass estimation from X-ray variability measurements in AGN

We propose a new method of estimation of the black hole masses in AGN based on the normalized excess variance, sigma_{nxs}^2. We derive a relation between sigma_{nxs}^2, the length of the observation, T, the light curve bin size, Delta t, and the black hole mass, assuming that (i) the power spectrum above the high frequency break, f_{bf}, has a slope of -2, (ii) the high frequency break scales with black hole mass, (iii) the power spectrum amplitude (in 'frequency x power' space) is universal and (iv) sigma_{nxs}^2 is calculated from observations of length T < 1/f_{bf}. Values of black hole masses in AGN obtained with this method are consistent with estimates based on other techniques such as reverberation mapping or the Mbh-stellar velocity dispersion relation. The method is formally equivalent to methods based on power spectrum scaling with mass but the use of the normalized excess variance has the big advantage of being applicable to relatively low quality data.Comment: 5 pages, 1 figure, 1 table, accepted for publication in MNRAS Letter. Added minor change on page 5 - corrected mistake (1/T 1/T > nu

The energetics of the central engine in the powerful quasar 3C 298

Galaxie

PG 1211+143: probing high frequency lags in a high mass AGN

We present the timing analysis of the four archived XMM-Newton observations of PG 1211+143. The source is well-known for its spectral complexity, comprising a strong soft-excess and different absorption systems. Soft energy band (0.3-0.7 keV) lags are detected over all the four observations, in the frequency range \nu \lsim 6 \times 10^{-4} Hz, where hard lags, similar to those observed in black hole X-ray binaries, are usually detected in smaller mass AGN. The lag magnitude is energy-dependent, showing two distinct trends apparently connectable to the two flux levels at which the source is observed. The results are discussed in the context of disk- and/or corona-reprocessing scenarios, and of disk wind models. Similarities with the high-frequency negative lag of 1H 0707-495 are highlighted, and, if confirmed, they would support the hypothesis that the lag in PG 1211+143 represents the signature of the same underlying mechanism, whose temporal characteristics scale with the mass of the central object.Comment: 6 pages, 6 figures, accepted for publication in MNRAS Letter