How Oregon State University Programming Supports the Development of Agritourism Activities (Including Farm-Direct Sales) in Oregon

Oregon State University (OSU) faculty members have supported the success of agriculture producers and their businesses for more than 100 years. Through research, education and community engagement, OSU faculty have helped agriculture producers and value-added operators respond to threats and opportunities in a manner that has brought vitality and sustainability to the state’s multi-billion dollar agriculture industry. A segment of OSU faculty members has been supporting the growth of an emerging sector of agriculture in Oregon—known as agritourism—for many years. Agritourism includes farm-direct sales and four other categories of agritourism activities.

The contribution of X-linked coding variation to severe developmental disorders

Abstract: Over 130 X-linked genes have been robustly associated with developmental disorders, and X-linked causes have been hypothesised to underlie the higher developmental disorder rates in males. Here, we evaluate the burden of X-linked coding variation in 11,044 developmental disorder patients, and find a similar rate of X-linked causes in males and females (6.0% and 6.9%, respectively), indicating that such variants do not account for the 1.4-fold male bias. We develop an improved strategy to detect X-linked developmental disorders and identify 23 significant genes, all of which were previously known, consistent with our inference that the vast majority of the X-linked burden is in known developmental disorder-associated genes. Importantly, we estimate that, in male probands, only 13% of inherited rare missense variants in known developmental disorder-associated genes are likely to be pathogenic. Our results demonstrate that statistical analysis of large datasets can refine our understanding of modes of inheritance for individual X-linked disorders

Global urban environmental change drives adaptation in white clover

Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale

Crime victimization among injection drug users

This study uses routine activity theory to examine violent and property crime victimization among a sample of 308 injection drug users (IDUs). We estimate prevalence rates and identify factors that contribute to the victimization of IDUs. The findings suggest that victimization rates of IDUs were much higher than rates found for the general urban population. Generally, crime involvement did not contribute significantly to victimization risk. Use of crack-cocaine increased the likelihood of property crime victimization whereas heroin use decreased the probability of both violent and property crime victimization. Other drug lifestyle activities (i.e., waiting in uncomfortable situations to buy drugs) also affected victimization risk Finally, the results suggest that victimization differed by age and by gender, despite controls for drug use and drug lifestyle activities. Explanations for these results are offered. </jats:p

The consistency of self-reported HIV risk behavior among injection drug users

OBJECTIVES. Most studies of risk factors for human immunodeficiency virus (HIV) rely heavily on retrospective self-reports. The degree to which these reports provide reliable information has received little research attention. The purpose of this study was to assess the extent to which the reliability of retrospective self-report data is affected over time. METHODS. Data were examined from a longitudinal study of risk behaviors among injection drug users. Structured interviews were administered to 366 injection drug users who were asked to recall behaviors that they had reported 6, 12, or 18 months earlier. RESULTS. Kappa coefficients showed moderate initial memory loss for injection and sexual risk behaviors. After 6 months, time had little effect on the ability of injection drug users to recall injection and sexual risk behaviors. For ordinal measures of risk, subjects who gave different reports over time were most likely to disagree by one response category. CONCLUSIONS. These findings support the use of retrospective self-reports in assessing HIV risk behaviors among injection drug users. Retrospective inquiry is likely to remain an important method for collecting data over time

Employment Among Chronic Drug Users at Baseline and 6-Month Follow-Up

Most studies of unemployment among chronic drug users (CDUs) are drug-user treatment-based and there is little information on employment/unemployment among CDUs not in treatment. Between June 2003 and September 2004, 492 CDUs in Miami-Dade, Florida, were administered a quantitative survey at baseline and 6 months later; employment status was measured. Descriptive statistics showed that only 15% were employed at both periods, an equal percentage becoming employed and unemployed at 6 months. The majority of CDUs were unemployed at both time periods. Men were more likely than women to exhibit consistent employment over the two time periods. The study's limitations are noted and future research is suggested. This study was IRB-approved and funded by the National Institute on Drug Abuse