502 research outputs found

    LerĂžy Seafood Group ASA : Strategisk regnskapsanalyse og verdivurdering

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    I denne masterutredningen er det blitt utfĂžrt en omfattende strategisk regnskapsanalyse og verdivurdering av LerĂžy Seafood Group ASA (LerĂžy). Masteroppgavens formĂ„l er Ă„ estimere verdien av egenkapitalen per 31. desember 2022. Fundamental verdivurdering er oppgavens hovedmetode, supplert med komparativ verdsettelse. Det endelige verdiestimatet ble avslutningsvis sammenlignet med bĂžrskurs pĂ„ verdsettelsestidspunktet, for Ă„ avgi en anbefalt handlingsstrategi av LerĂžy-aksjen. FĂžrste del av masteroppgaven begynner med en presentasjon av LerĂžy og oppdrettsbransjen, deretter fĂžlger strategisk analyse. Den eksterne bransjeanalysen belyser at oppdrettsnĂŠringen er attraktiv, dette bekreftes senere av lĂžnnsomhetsanalysen som viser en bransjefordel pĂ„ 7,3 %. Restriktiv konsesjonspolitikk medfĂžrer hĂžye inngangsbarrierer som fĂžlgelig demper konkurransen. MiljĂžmessige utfordringer er bransjens stĂžrste trussel og svekker produksjonen av laks. HĂžy etterspĂžrsel etter laks som sĂ„dan kombinert med begrensninger i tilbudet, driver prisene opp. Internanalysen avdekker at LerĂžy ikke har varig konkurransefortrinn. Den negative ressursfordelen tilskrives en marginulempe, som beror pĂ„ at LerĂžy har hĂžyere driftskostnader per krone i driftsinntekter enn bransjen. Dette mener vi skyldes hĂžyere relative fĂŽrkostnader. Rentabilitetsanalysen konkluderer med negativ ressursfordel pĂ„ -2,4%. Del 2 av oppgaven begynner med en omfattende omgrupperings- og justeringsprosess av LerĂžy og de komparative selskapenes regnskap. Fra regnskapsanalysen fremgikk det at LerĂžy ikke innehar likviditets- eller soliditetsrisiko, og er godt rustet til Ă„ hĂ„ndtere potensielle nedgangstider. Videre ble selskapets historiske avkastningskrav estimert, samt utarbeiding av rentabilitetsanalyser. LĂžnnsomhetsanalysen slo fast at LerĂžy i perioden 2016-2022 har oppnĂ„dd strategisk fordel pĂ„ 5,58%, bakteppet er i hovedsak bransjefordelen. I siste del av oppgaven ble det utarbeidet et fremtidsregnskap og -krav. Usikkerhet i dag vedrĂžrende grunnrenteskatt vil medfĂžre en lavere strategisk fordel pĂ„ kort sikt, men mot steady state har vi estimert en vekst pĂ„ 3,29%. Den fundamentale verdsettelsen resulterte i et verdiestimat pĂ„ 55,5 kr per aksje. For Ă„ fastslĂ„ usikkerheten i verdiestimatet ble det foretatt en simuleringsanalyse av de viktigste budsjettdriverne. Analysen fastslo hĂžy usikkerhet, verdiestimatet var sĂŠrlig fĂžlsomt overfor endringer i driftsinntektsvekst og netto driftsmargin ved budsjetthorisonten. Vi benyttet multipler som supplerende verdsettelse, gjennomsnittet av disse ble 71,17 kr per aksje. Ved Ă„ vekte den fundamentale metoden 80 % og den komparative verdsettelsen 20 %, kom vi frem til et endelig estimat pĂ„ kroner 58,6 per aksje. Den 23. mai 2023 var bĂžrskursen 50,8, dermed konkluderer oppgaven med kjĂžpsanbefaling pĂ„ aksjen. Årsaken til at vĂ„rt estimat er hĂžyere enn bĂžrskursen, skyldes i hovedsak at markedet er mer pessimistisk til grunnrenteskatten.nhhma

    PERAN GEREJA DALAM MENINGKATKAN MOTIVASI UNTUK BERIBADAH SECARA TATAP MUKA PASCA PANDEMI COVID

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    After two years of a pandemic where worship activities could not be carried out and were limited, the government began to relax the rules for worship, and churches resumed their activities and held face-to-face worship. Even though some congregations are starting to come to worship face-to-face enthusiastically, others are still choosing to worship online. During the hybrid worship period, where online services are still held simultaneously as face-to-face services, the church seeks various ways to invite the entire congregation back to attend services. Based on direct observations and interviews with pastors and congregations that have attended, various factors have been found that can be a driving force for congregations longing to attend face-to-face activities; the church also uses various creative ways to provoke the desire of congregations that are not present to be able to feel and remember the enjoyment worship directly. Efforts to attract the congregation to return to attendance, thanks to the role of the pastor's attention to the congregation and various supporting factors, have resulted in the return of almost the entire congregation for face-to-face worship.Setelah dua tahun pandemi dimana kegiatan beribadah tidak dapat dilakukan dan dibatasi, pemerintah mulai melonggarkan aturan beribadah, gereja memulai kembali beraktifitas dan mengadakan ibadah tatap muka. Walaupun sebagian jemaat mulai antusias datang beribadah tatap muka, sebagian jemaat yang tetap memilih beribadah daring. Dalam masa ibadah hybrid dimana ibadah on line masih dilaksanakan bersamaan ibadah tatap muka, gereja mencari berbagai cara kembali mengajak seluruh jemaat kembali hadir dalam ibadah. Berdasarkan pengamatan dan wawancara secara langsung dengan gembala dan jemaat yang telah hadir didapati berbagai faktor yang dapat menjadi pendorong untuk jemaat rindu untuk hadir dalam kegiatan tatap muka, gereja juga menggunakan berbagai cara yang kreatif untuk memancing keinginan jemaat yang belum hadir dapat merasakan dan mengingat kembali kenikmatan beribadah secara langsung. Usaha untuk menarik jemaat untuk kembali hadir berkat peran perhatian gembala kepada jemaat dan berbagai faktor pendukungnya membuahkan hasil dengan kembali hadirnya hampir seluruh jemaat untuk beribadah tatap muka

    Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force

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    Background: Therapeutic targets have been defined for diseases like diabetes, hypertension or rheumatoid arthritis and adhering to them has improved outcomes. Such targets are just emerging for spondyloarthritis (SpA). Objective: To define the treatment target for SpA including ankylosing spondylitis and psoriatic arthritis (PsA) and develop recommendations for achieving the target, including a treat-to-target management strategy. Methods: Based on results of a systematic literature review and expert opinion, a task force of expert physicians and patients developed recommendations which were broadly discussed and voted upon in a Delphi-like process. Level of evidence, grade and strength of the recommendations were derived by respective means. The commonalities between axial SpA, peripheral SpA and PsA were discussed in detail. Results: Although the literature review did not reveal trials comparing a treat-to-target approach with another or no strategy, it provided indirect evidence regarding an optimised approach to therapy that facilitated the development of recommendations. The group agreed on 5 overarching principles and 11 recommendations; 9 of these recommendations related commonly to the whole spectrum of SpA and PsA, and only 2 were designed separately for axial SpA, peripheral SpA and PsA. The main treatment target, which should be based on a shared decision with the patient, was defined as remission, with the alternative target of low disease activity. Follow-up examinations at regular intervals that depend on the patient's status should safeguard the evolution of disease activity towards the targeted goal. Additional recommendations relate to extra-articular and extramusculoskeletal aspects and other important factors, such as comorbidity. While the level of evidence was generally quite low, the mean strength of recommendation was 9-10 (10: maximum agreement) for all recommendations. A research agenda was formulated. Conclusions: The task force defined the treatment target as remission or, alternatively, low disease activity, being aware that the evidence base is not strong and needs to be expanded by future research. These recommendations can inform the various stakeholders about expert opinion that aims for reaching optimal outcomes of SpA

    Immunological corollary of the pulmonary mycobiome in bronchiectasis:The Cameb study

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    Understanding the composition and clinical importance of the fungal mycobiome was recently identified as a key topic in a “research priorities” consensus statement for bronchiectasis. Patients were recruited as part of the CAMEB study: an international multicentre cross-sectional Cohort of Asian and Matched European Bronchiectasis patients. The mycobiome was determined in 238 patients by targeted amplicon shotgun sequencing of the 18S–28S rRNA internally transcribed spacer regions ITS1 and ITS2. Specific quantitative PCR for detection of and conidial quantification for a range of airway Aspergillus species was performed. Sputum galactomannan, Aspergillus specific IgE, IgG and TARC (thymus and activation regulated chemokine) levels were measured systemically and associated to clinical outcomes. The bronchiectasis mycobiome is distinct and characterised by specific fungal genera, including Aspergillus, Cryptococcus and Clavispora. Aspergillus fumigatus (in Singapore/Kuala Lumpur) and Aspergillus terreus (in Dundee) dominated profiles, the latter associating with exacerbations. High frequencies of Aspergillus-associated disease including sensitisation and allergic bronchopulmonary aspergillosis were detected. Each revealed distinct mycobiome profiles, and associated with more severe disease, poorer pulmonary function and increased exacerbations. The pulmonary mycobiome is of clinical relevance in bronchiectasis. Screening for Aspergillus-associated disease should be considered even in apparently stable patients.MOE (Min. of Education, S’pore)NMRC (Natl Medical Research Council, S’pore)Published versio

    Distinct 'Immuno-Allertypes' of Disease and High Frequencies of Sensitisation in Non-Cystic-Fibrosis Bronchiectasis

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    Rationale: Allergic sensitization is associated with poor clinical outcomes in asthma, chronic obstructive pulmonary disease, and cystic fibrosis; however, its presence, frequency, and clinical significance in non–cystic fibrosis bronchiectasis remain unclear. Objectives: To determine the frequency and geographic variability that exists in a sensitization pattern to common and specific allergens, including house dust mite and fungi, and to correlate such patterns to airway immune-inflammatory status and clinical outcomes in bronchiectasis. Methods: Patients with bronchiectasis were recruited in Asia (Singapore and Malaysia) and the United Kingdom (Scotland) (n = 238), forming the Cohort of Asian and Matched European Bronchiectasis, which matched recruited patients on age, sex, and bronchiectasis severity. Specific IgE response against a range of common allergens was determined, combined with airway immune-inflammatory status and correlated to clinical outcomes. Clinically relevant patient clusters, based on sensitization pattern and airway immune profiles (“immunoallertypes”), were determined. Measurements and Main Results: A high frequency of sensitization to multiple allergens was detected in bronchiectasis, exceeding that in a comparator cohort with allergic rhinitis (n = 149). Sensitization was associated with poor clinical outcomes, including decreased pulmonary function and more severe disease. “Sensitized bronchiectasis” was classified into two immunoallertypes: one fungal driven and proinflammatory, the other house dust mite driven and chemokine dominant, with the former demonstrating poorer clinical outcome. Conclusions: Allergic sensitization occurs at high frequency in patients with bronchiectasis recruited from different global centers. Improving endophenotyping of sensitized bronchiectasis, a clinically significant state, and a “treatable trait” permits therapeutic intervention in appropriate patients, and may allow improved stratification in future bronchiectasis research and clinical trials.Ministry of Education (MOE)Ministry of Health (MOH)National Medical Research Council (NMRC)Published versionSupported by the Singapore Ministry of Health’s National Medical Research Council under its Transition Award NMRC/TA/0048/2016 (S.H.C.) and Changi General Hospital Research grant CHF2016.03-P (T.B.L.). The work performed at NUS was supported by the Singapore Ministry of Education Academic Research Fund, SIgN, and National Medical Research Council grants N-154-000-038-001, R-154-000-404-112, R-154-000-553-112, R-154-000-565-112, R-154-000-630-112, R-154-000-A08-592, R-154-000-A27-597, SIgN-06-006, SIgN-08-020, and NMRC/1150/2008 (F.T.C.); J.D.C. is supported by the GSK/British Lung Foundation Chair of Respiratory Research

    Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

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    The production of tt‟ , W+bb‟ and W+cc‟ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓΜ , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of tt‟t\overline{t}, W+bb‟W+b\overline{b} and W+cc‟W+c\overline{c} is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 ±\pm 0.02 \mbox{fb}^{-1}. The WW bosons are reconstructed in the decays W→ℓΜW\rightarrow\ell\nu, where ℓ\ell denotes muon or electron, while the bb and cc quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

    Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

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    Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a ZZ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 <pT<100< p_{\textrm{T}} < 100 GeV and in the pseudorapidity range 2.5<η<42.5 < \eta < 4. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb−1^{-1}. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages

    Study of the B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

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    The decay B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} is studied in proton-proton collisions at a center-of-mass energy of s=13\sqrt{s}=13 TeV using data corresponding to an integrated luminosity of 5 fb−1\mathrm{fb}^{-1} collected by the LHCb experiment. In the Λc+K−\Lambda_{c}^+ K^{-} system, the Ξc(2930)0\Xi_{c}(2930)^{0} state observed at the BaBar and Belle experiments is resolved into two narrower states, Ξc(2923)0\Xi_{c}(2923)^{0} and Ξc(2939)0\Xi_{c}(2939)^{0}, whose masses and widths are measured to be m(Ξc(2923)0)=2924.5±0.4±1.1 MeV,m(Ξc(2939)0)=2938.5±0.9±2.3 MeV,Γ(Ξc(2923)0)=0004.8±0.9±1.5 MeV,Γ(Ξc(2939)0)=0011.0±1.9±7.5 MeV, m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV}, where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt Λc+K−\Lambda_{c}^{+} K^{-} sample. Evidence of a new Ξc(2880)0\Xi_{c}(2880)^{0} state is found with a local significance of 3.8 σ3.8\,\sigma, whose mass and width are measured to be 2881.8±3.1±8.5 MeV2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV} and 12.4±5.3±5.8 MeV12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}, respectively. In addition, evidence of a new decay mode Ξc(2790)0→Λc+K−\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-} is found with a significance of 3.7 σ3.7\,\sigma. The relative branching fraction of B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} with respect to the B−→D+D−K−B^{-} \to D^{+} D^{-} K^{-} decay is measured to be 2.36±0.11±0.22±0.252.36 \pm 0.11 \pm 0.22 \pm 0.25, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages

    Participatory Research for Low-resourced Machine Translation:A Case Study in African Languages

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    Research in NLP lacks geographic diversity, and the question of how NLP can be scaled to low-resourced languages has not yet been adequately solved. "Low-resourced"-ness is a complex problem going beyond data availability and reflects systemic problems in society. In this paper, we focus on the task of Machine Translation (MT), that plays a crucial role for information accessibility and communication worldwide. Despite immense improvements in MT over the past decade, MT is centered around a few high-resourced languages. As MT researchers cannot solve the problem of low-resourcedness alone, we propose participatory research as a means to involve all necessary agents required in the MT development process. We demonstrate the feasibility and scalability of participatory research with a case study on MT for African languages. Its implementation leads to a collection of novel translation datasets, MT benchmarks for over 30 languages, with human evaluations for a third of them, and enables participants without formal training to make a unique scientific contribution. Benchmarks, models, data, code, and evaluation results are released under https://github.com/masakhane-io/masakhane-mt

    Angular analysis of the B-0 -&gt; K*(0) e(+) e(-) decay in the low-q(2) region

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    An angular analysis of the B0→K∗0e+e−B^0 \rightarrow K^{*0} e^+ e^- decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 {\mbox{fb}^{-1}}, collected by the LHCb experiment in pppp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2q^2) interval between 0.002 and 1.120 GeV2 ⁣/c4{\mathrm{\,Ge\kern -0.1em V^2\!/}c^4}. The angular observables FLF_{\mathrm{L}} and ATReA_{\mathrm{T}}^{\mathrm{Re}} which are related to the K∗0K^{*0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL=0.16±0.06±0.03F_{\mathrm{L}}= 0.16 \pm 0.06 \pm0.03 and ATRe=0.10±0.18±0.05A_{\mathrm{T}}^{\mathrm{Re}} = 0.10 \pm 0.18 \pm 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)A_{\mathrm{T}}^{(2)} and ATImA_{\mathrm{T}}^{\mathrm{Im}} which are sensitive to the photon polarisation in this q2q^2 range, are found to be AT(2)=−0.23±0.23±0.05A_{\mathrm{T}}^{(2)} = -0.23 \pm 0.23 \pm 0.05 and ATIm=0.14±0.22±0.05A_{\mathrm{T}}^{\mathrm{Im}} =0.14 \pm 0.22 \pm 0.05. The results are consistent with Standard Model predictions.An angular analysis of the B0^{0} → K^{*}^{0} e+^{+} e−^{−} decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 fb−1^{−1}, collected by the LHCb experiment in pp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2^{2}) interval between 0.002 and 1.120 GeV2^{2} /c4^{4}. The angular observables FL_{L} and ATRe_{T}^{Re} which are related to the K^{*}^{0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL_{L} = 0.16 ± 0.06 ± 0.03 and ATRe_{T}^{Re}  = 0.10 ± 0.18 ± 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)_{T}^{(2)} and ATIm_{T}^{Im} which are sensitive to the photon polarisation in this q2^{2} range, are found to be AT(2)_{T}^{(2)}  = − 0.23 ± 0.23 ± 0.05 and ATIm_{T}^{Im}  = 0.14 ± 0.22 ± 0.05. The results are consistent with Standard Model predictions.An angular analysis of the B0→K∗0e+e−B^0 \rightarrow K^{*0} e^+ e^- decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 {\mbox{fb}^{-1}}, collected by the LHCb experiment in pppp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2q^2) interval between 0.002 and 1.120 GeV2 ⁣/c4{\mathrm{\,Ge\kern -0.1em V^2\!/}c^4}. The angular observables FLF_{\mathrm{L}} and ATReA_{\mathrm{T}}^{\mathrm{Re}} which are related to the K∗0K^{*0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL=0.16±0.06±0.03F_{\mathrm{L}}= 0.16 \pm 0.06 \pm0.03 and ATRe=0.10±0.18±0.05A_{\mathrm{T}}^{\mathrm{Re}} = 0.10 \pm 0.18 \pm 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)A_{\mathrm{T}}^{(2)} and ATImA_{\mathrm{T}}^{\mathrm{Im}} which are sensitive to the photon polarisation in this q2q^2 range, are found to be AT(2)=−0.23±0.23±0.05A_{\mathrm{T}}^{(2)} = -0.23 \pm 0.23 \pm 0.05 and ATIm=0.14±0.22±0.05A_{\mathrm{T}}^{\mathrm{Im}} =0.14 \pm 0.22 \pm 0.05. The results are consistent with Standard Model predictions
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