3,329 research outputs found
Assessment of unintentional islanding operations in distribution networks with large induction motors
This paper is aimed at assessing the impact of unintentional islanding operations (IOs) in the presence of large induction motors (IMs) within distribution networks (DNs). When a fault occurs,followingthecircuitbreaker(CB)faultclearing,theIMsacttransientlyasgenerators,duetoits inertia, until the CB reclosing takes place. The present work is the outcome of a project carried out in a small DN, where ¿eld measurements were recorded over two years. This paper provides a detailed description of the test system, a selected list of ¿eld measurements, and a discussion on modeling guidelinesusedtocreatethemodeloftheactualpowersystem. Themaingoalistovalidatethesystem model by comparing ¿eld measurements with simulation results. The comparison of simulations and ¿eld measurements prove the appropriateness of the modeling guidelines used in this work and highlight the high accuracy achieved in the implemented three-phase Matlab/Simulink modelPostprint (published version
A survey of genes encoding H2O2-producing GMC oxidoreductases in 10 Polyporales genomes
The genomes of three representative Polyporales (Bjerkandera adusta, Phlebia brevispora and a member of the Ganoderma lucidum complex) recently were sequenced to expand our knowledge on the diversity and distribution of genes involved in degradation of plant polymers in this Basidiomycota order, which includes most wood-rotting fungi. Oxidases, including members of the glucose-methanol-choline (GMC) oxidoreductase superfamily, play a central role in the above degradative process because they generate extracellular H2O2 acting as the ultimate oxidizer in both white-rot and brown-rot decay. The survey was completed by analyzing the GMC genes in the available genomes of seven more species to cover the four Polyporales clades. First, an in silico search for sequences encoding members of the aryl-alcohol oxidase, glucose oxidase, methanol oxidase, pyranose oxidase, cellobiose dehydrogenase and pyranose dehydrogenase families was performed. The curated sequences were subjected to an analysis of their evolutionary relationships, followed by estimation of gene duplication/ reduction history during fungal evolution. Second, the molecular structures of the near one hundred GMC oxidoreductases identified were modeled to gain insight into their structural variation and expected catalytic properties. In contrast to ligninolytic peroxidases, whose genes are present in all white-rot Polyporales genomes and absent from those of brown-rot species, the H2O2-generating oxidases are widely distributed in both fungal types. This indicates that the GMC oxidases provide H2O2 for both ligninolytic peroxidase activity (in white-rot decay) and Fenton attack on cellulose (in brown-rot decay), after the transition between both decay patterns in Polyporales occurred
Terminal Antennas in ACE2
The ACE Network of Excellence was a European Commission funded Network of Excellence, which lasted from 2004 to 2007. One of the activities performed by this Network was in the frame of terminal antennas. In this activity, three aspects were covered in three projects: Small antenna technologies, small terminal antenna technologies and benchmarking of small terminal antennas measurement facilities. The overall aim was to identify the newest trends in antenna design and measurement for personal communications devices, and suggest novel solutions and design methodologies for various applications. The results of this work are presented in this paper
Incidence of Hypertension in a Cohort of Spanish University Graduates:The SUN Study
Hypertension is a major public health problem. However,
no estimates of age- and sex-specific incidences are available
for the Spanish population. Our objective was to estimate
the incidence of hypertension in a cohort of university
graduates in Spain. We followed up 5648 individuals aged
25-65 years who were initially free of hypertension, diabetes,
and cardiovascular disease for a median of 30 months. New
diagnoses of hypertension were identified using mailed
questionnaires. We validated the self-reported diagnosis of
hypertension. In 18 250 person-years of follow-up, we
identified 248 new cases of hypertension. The unadjusted
incidences of hypertension in women and men were 8.2 per
1000 person-years (95% CI, 6.7-10.1) and 21.8 per 1000
person-years (95% CI, 18.6-25.4), respectively. The
cumulative probability of receiving a medical diagnosis of
hypertension by the age of 65 years was 50% among women
and 72% among men. In conclusion, we have provided new
evidence confirming that hypertension is one of the most
important public health problems in Spain
Situación actual del personal técnico-deportivo en las empresas del sector en la Comunidad Valenciana
Actualmente, el tema de los recursos humanos está produciendo un fuerte impacto en España y sólo hay que acercarse a la bibliografía empresarial para comprobar que el estudio del sector de la actividad física y el deporte representa un campo de interés científico y social que requiere ser investigado. Mediante una metodología cuantitativa de corte descriptivo y mediante el empleo de la entrevista estandarizada como instrumento de recogida de información se reproducen aquellas características más relevantes observadas en la Comunidad Valenciana. Los resultados explican que las personas que trabajan en funciones físico-deportivas en empresas del sector son mayoritariamente hombres jóvenes que desarrollan una amplia variedad de las mismas, con situaciones laborales en las que no existe contratación y manifestando una elevada temporalidad. Asimismo, el estudio revela que más de la mitad de las personas desempeñan su trabajo con una duración laboral que no supera los cuatro años, existiendo personas sin titulación oficial de actividad física y deporte, y siendo el aspecto más importante para encontrar trabajo los contactos personales
SNP rs403212791 in exon 2 of the MTNR1A gene is associated with reproductive seasonality in the Rasa aragonesa sheep breed
The aim of this study was to characterize and identify causative SNPs in the MTNR1A gene responsible for the reproductive seasonality traits in the Rasa aragonesa sheep breed. A total of 290 ewes (155, 84 and 51 mature, young and ewe lambs, respectively) from one flock were controlled from January to August. The following three reproductive seasonality traits were considered: the total days of anoestrus (TDA) and the progesterone cycling months (P4CM); both ovarian function seasonality traits based on blood progesterone levels; and the oestrus cycling months (OCM) based on oestrous detection, which indicate behavioural signs of oestrous. We have sequenced the total coding region plus 733 and 251 bp from the promoter and 3'-UTR regions, respectively, from the gene in 268 ewes. We found 9 and 4 SNPs associated with seasonality traits in the promoter (for TDA and P4CM) and exon 2 (for the three traits), respectively. The SNPs located in the gene promoter modify the putative binding sites for various trans-acting factors. In exon 2, two synonymous SNPs affect RFLP sites, rs406779174/RsaI (for the three traits) and rs430181568/MnlI (for OCM), and they have been related with seasonal reproductive activity in previous association studies with other breeds. SNP rs400830807, which is located in the 3'-UTR, was associated with the three traits, but this did not modify the putative target sites for ovine miRNAs according to in silico predictions. Finally, the SNP rs403212791 (NW_014639035.1: g.15099004G > A), which is also associated with the three seasonality phenotypes, was the most significant SNP detected in this study and was a non-synonymous polymorphism, leading a change from an Arginine to a Cysteine (R336C). Haplotype analyses confirmed the association results and showed that the effects found for the seasonality traits were caused by the SNPs located in exon 2. We have demonstrated that the T allele in the SNP rs403212791 in the MNTR1A gene is associated with a lower TDA and higher P4CM and OCM values in the Rasa Aragonesa breed
A survey of genes encoding H2O2-producing GMC oxidoreductases in 10 Polyporales genomes
The genomes of three representative Polyporales (Bjerkandera adusta, Phlebia brevispora and a member of the Ganoderma lucidum complex) recently were sequenced to expand our knowledge on the diversity and distribution of genes involved in degradation of plant polymers in this Basidiomycota order, which includes most wood-rotting fungi. Oxidases, including members of the glucose-methanol-choline (GMC) oxidoreductase superfamily, play a central role in the above degradative process because they generate extracellular H2O2 acting as the ultimate oxidizer in both white-rot and brown-rot decay. The survey was completed by analyzing the GMC genes in the available genomes of seven more species to cover the four Polyporales clades. First, an in silico search for sequences encoding members of the aryl-alcohol oxidase, glucose oxidase, methanol oxidase, pyranose oxidase, cellobiose dehydrogenase and pyranose dehydrogenase families was performed. The curated sequences were subjected to an analysis of their evolutionary relationships, followed by estimation of gene duplication/ reduction history during fungal evolution. Second, the molecular structures of the near one hundred GMC oxidoreductases identified were modeled to gain insight into their structural variation and expected catalytic properties. In contrast to ligninolytic peroxidases, whose genes are present in all white-rot Polyporales genomes and absent from those of brown-rot species, the H2O2-generating oxidases are widely distributed in both fungal types. This indicates that the GMC oxidases provide H2O2 for both ligninolytic peroxidase activity (in white-rot decay) and Fenton attack on cellulose (in brown-rot decay), after the transition between both decay patterns in Polyporales occurred
Cytotoxic effect against 3T3 fibroblasts cells of saffron floral bio-residues extracts
For every kilogram of saffron spice produced, about 63 kg of floral bio-residues (FB) (tepals, stamens and styles) are thrown away. Extracts of these bio-residues in water (W1), water:HCl (100:1, v/v) (W2), ethanol (E3), ethanol:HCl (100:1, v/v) (E4), dichloromethane (D5) and hexane (H6) were prepared. Their composition in flavonols and anthocyanins, and their effect on cell viability were determined. W1 was the richest in kaempferol 3-sophoroside (30.34 mg/g dry FB) and delphinidin 3,5-diglucoside (15.98 mg/g dry FB). The highest tested concentration (900 μg/ml) of W1, W2, E4, D5 and H6 did not significantly decrease the cell viability. Only E3 at that concentration caused a significant decrease of 38% in the cell viability. Therefore, all extracts studied are not cytotoxic at concentrations lower than 900 μg/ml, and W1 is proposed as the optimal for food applications due to its greater contribution of phenolic compounds
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