A Rural New Mexico Village\u27s Perspectives of Local Problems, Strengths and Solutions: Asset Mapping and Issue Prioritization for Community Development

Understanding community perspectives regarding local needs, problems and assets is an important step towards community development. Needs assessments help identify gaps in public policies and/or available public services, such as public utilities, public safety, education, housing, health, and transportation, as well as asses the local/regional economy that affect the quality of life of residents. Assessment data helps to inform the development of useful interventions and data informed decision-making processes that can later be evaluated for their effectiveness and/or to make improvements and adjustments to public policies, and local initiatives to reach community goals. In rural communities, needs assessments can help prioritize issues/needs/wants among the various community stakeholders and inform comprehensive planning, program and policy development, and allocation of limited resources. This community-based action research examined the needs, problems, and local assets in the rural community of Magdalena, New Mexico. Input obtained from community stakeholders including citizens, village leaders, and businesses was designed to help support and strengthen the rural village volunteer-based governance system, improve community relations and civic engagement, and increase support for community-based organizations and businesses that serve the local community. The assessment was conducted in six phases, over a 24-month period and includes: 1) project planning, 2) methodology design, 3) data collection, 4) analysis, 5) reporting and 6) dissemination of the findings to the community. The needs assessment data collection included a mix methods process, in which key informant interviews, a communitywide survey, and text analysis provided multiple avenues to gain community perspectives. A literature review and examination of existing data that pertain to the study was included. The results of the study produced a Village of Magdalena Asset Map of the community’s resources, as well as prioritization of concerns by community members: which included economic development, public safety, food security, and youth resources and recreation

Order of convergence of the finite element method for the p(x)-Laplacian

In this work, we study the rate of convergence of the finite element method for the p(x) Laplacian (⁠1<p1≤p(x)≤p2≤2⁠) in a bounded convex domain in R2⁠.Fil: Del Pezzo, Leandro. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Matemática; ArgentinaFil: Martinez, Sandra Rita. Universidad Nacional de General Sarmiento. Instituto de Ciencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Matemática; Argentin

A comprehensive resource for induced pluripotent stem cells from patients with primary tauopathies

Primary tauopathies are characterized neuropathologically by inclusions containing abnormal forms of the microtubule-associated protein tau (MAPT) and clinically by diverse neuropsychiatric, cognitive, and motor impairments. Autosomal dominant mutations in the MAPT gene cause heterogeneous forms of frontotemporal lobar degeneration with tauopathy (FTLD-Tau). Common and rare variants in the MAPT gene increase the risk for sporadic FTLD-Tau, including progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). We generated a collection of fibroblasts from 140 MAPT mutation/risk variant carriers, PSP, CBD, and cognitively normal controls; 31 induced pluripotent stem cell (iPSC) lines from MAPT mutation carriers, non-carrier family members, and autopsy-confirmed PSP patients; 33 genome engineered iPSCs that were corrected or mutagenized; and forebrain neural progenitor cells (NPCs). Here, we present a resource of fibroblasts, iPSCs, and NPCs with comprehensive clinical histories that can be accessed by the scientific community for disease modeling and development of novel therapeutics for tauopathies

Ghost crab predation of loggerhead turtle eggs across thermal habitats

The reproductive success of sea turtles is highly influenced by the environmental and biological conditions of the nesting beach. Maio Island, Cabo Verde, one of the main nesting sites for the Northeast Atlantic loggerhead subpopulation, displays marked heterogeneity of sand coloration, with dark, mixed and light sandy beaches, resulting in different thermal habitats. Considering that sand temperature can influence both sea turtle embryo development and predatory activity by ghost crabs – the main predators of clutches and hatchlings at Cabo Verde – we surveyed loggerhead nesting beaches at Maio Island, with three sand colorations (‘beach type’), to assess: 1) the density and size of ghost crab burrows, as a proxy for ghost crab density and size, and 2) ghost crab predation on 70 loggerhead nests. We further assessed nest site selection, by considering the number of nesting activities and clutches laid across beach type. There were no evident trends in the distributions of ghost crab density and size between years or beach type. We found that ghost crab predation is a major source of mortality in Maio Island, affecting 67.8% (n = 59) of the nests. Ghost crab predation was variable between beaches, but generally, at the warmer dark sand beaches, clutch mortality was mostly caused by ghost crab predation (53.2%, n = 17), while at the mixed sand beaches mortality by predation was low (7.5%, n = 18), compared to mortality due to other causes (49.9%), indicating that other factors can also significantly impact clutch survival. The mixed sand beaches had more nesting activities and higher nest density (2.29/m2; 1.25/m2, respectively), compared to the light sand (0.72/m2; 0.35/m2) and the dark sand beaches (0.73/m2; 0.27/m2), suggesting a possible predation-free nesting preference. Our findings show that some beaches are in need of nest protection, thus we recommend both in situ nest protection and egg translocation to safe hatcheries, depending on the threats identified, to enhance clutch survival at such heterogeneous nesting areas as Maio Island.Fundação para a Ciência e Tecnologia - FCTinfo:eu-repo/semantics/publishedVersio

Critical Professional Development: Centering the Social Justice Needs of Teachers

As a response to increasingly technocratic, top-down teacher professional development that we refer to as antidialogical professional development (APD), this article theorizes a model of critical professional development (CPD) where teachers are engaged as politically-aware individuals who have a stake in teaching and transforming society.  Illuminating three US based case studies of CPD that emerged in response to the unmet needs of justice-oriented teachers- The People’s Education Movement, New York Collective of Radical Educators’ Inquiry to Action groups, and the Institute for Teachers of Color Committed to Racial Justice- this article uses Freire’s framework of dialogical action to analyze shared critical practices.  In each independent case, teachers were engaged in a cooperative dialectical process, there was a strong emphasis on unity amongst participants around their social justice goals, the structure was organized through shared power between teachers and organizers, and teacher and student needs were centered using a practice of cultural synthesis.  Reframing the possibilities of teacher professional development through this model of critical, dialogical practice, this article offers a critique of the banking methods and technical content traditionally used within APD, and provides insights into how teachers can successfully be positioned as experts in their own social justice-oriented professional growth

“Principales avances tecnológicos en el proceso de transformación del café y sus perspectivas”

En el proceso de transformación del café específicamente en el beneficiado húmedo, existe una conciencia generalizada sobre la necesidad de buscar soluciones de corto plazo que permitan reducir al máximo la contaminación del medio ambiente, sin afectar negativamente la productividad de sus industrias y la calidad final del grano. En materia de apropiación e innovación tecnológica; por lo general el beneficiador carece de un adecuado asesoramiento para identificar el proceso de reconversión que mejor se adapte a su situación particular. Las principales debilidades encontradas en la aplicación de la tecnología en el proceso de transformación del café es la falta de financiamiento tanto a productores como a beneficiadores de café lo que no les permite realizar innovaciones en su maquinaria, remodelaciones en sus beneficios y fincas y tienen que seguir trabajando con maquinaria obsoleta que utilizan desde hace 40 años. En la actualidad algunos productores con la ayuda de organismos internacionales han realizado cambios tecnológicos en el proceso de transformación del café teniendo un mayor impacto en el medioambiente con el uso de los subproductos del proceso de beneficiado húmedo en elaboración de compostajes (lombricultura, lagunas de filtración), conforman el beneficiado ecológico; en relación al beneficio seco algunos beneficios están haciendo uso de la clasificadora conocida como ojo electrónico. Las principales alternativas en maquinarias son las siguientes: En el beneficiado húmedo (Desmucilaginador mecánico que reduce el tiempo de fermentación, disminuye el consumo de agua en el despulpado, tornillos helicoidales que transportan café y pulpa en el despulpado ecológico); en el proceso Semi industrial (ojo electrónico, banda transportadora de sacos, mezcladora de café) lo que le permite una mayor productividad en el proceso de transformación del caf

Understanding pseudo-albinism in sole (Solea senegalensis): a transcriptomics and metagenomics approach

Pseudo-albinism is a pigmentation disorder observed in flatfish aquaculture with a complex, multi-factor aetiology. We tested the hypothesis that pigmentation abnormalities are an overt signal of more generalised modifications in tissue structure and function, using as a model the Senegalese sole and two important innate immune barriers, the skin and intestine, and their microbiomes. Stereological analyses in pseudo-albino sole revealed a significantly increased mucous cell number in skin (P < 0.001) and a significantly thicker muscle layer and lamina propria in gut (P < 0.001). RNA-seq transcriptome analysis of the skin and gut identified 573 differentially expressed transcripts (DETs, FDR < 0.05) between pseudo-albino and pigmented soles (one pool/tissue from 4 individuals/phenotype). DETs were mainly linked to pigment production, skin structure and regeneration and smooth muscle contraction. The microbiome (16 S rRNA analysis) was highly diverse in pigmented and pseudo-albino skin but in gut had low complexity and diverged between the two pigmentation phenotypes. Quantitative PCR revealed significantly lower loads of Mycoplasma (P < 0.05) and Vibrio bacteria (P < 0.01) in pseudo-albino compared to the control. The study revealed that pseudo-albinism in addition to pigmentation changes was associated with generalised changes in the skin and gut structure and a modification in the gut microbiome.Agência financiadora H2020 European Funds MSCA-RISE project 691102 Portuguese national funds from FCT - Foundation for Science and Technology UID/Multi/04326/2019 Portuguese national funds from the operational programme CRESC Algarve 2020 EMBRC. PT ALG-01-0145-FEDER-022121 Portuguese national funds from the operational programme COMPETE 2020 EMBRC. PT ALG-01-0145-FEDER-022121 European Union (EU) 654008 Fundacao para a Ciencia e a Tecnologia (FCT) SFRH/BPD/84033/2012 Portuguese Institute for Employment and Vocational Training 0068/ET/18info:eu-repo/semantics/publishedVersio

El método científico y el logro de competencia indaga en estudiantes de secundaria de una institución educativa Ancash, 2023

El objetivo principal del presente trabajo de investigación fue determinar la relación entre el método científico y el logro de la competencia indaga en los discentes de cuarto grado de secundaria de una institución educativa Ancash, 2023. La investigación fue de tipo cuantitativo en su nivel explicativo y diseño no experimental o transaccional. La muestra fue de 60 estudiantes, se utilizó como técnica la observación y como instrumento la escala de Likert; para el análisis de datos se empleó el Excel 2016 y estadístico SPSS versión 24. Los resultados se obtuvieron al aplicar una encuesta a los estudiantes para determinar si existe la relación entre las dimensiones del método científico y la competencia indaga, donde se determinó que existe relación; se evaluó la fiabilidad de los instrumentos con el Alfa de Cronbach, la prueba de normalidad de los datos a través de KolmogorovSmirnov, y se contrastó la hipótesis mediante el estadístico Rho de Spearman, cuyo valor de p=0.002 < 0.05, con lo cual se validó la hipótesis; así mismo, con los resultados de la prueba de normalidad, se concluye que existe relación entre las dimensiones del método científico y la competencia indaga

In Vitro Anti-Candida Activity of Lidocaine and Nitroglycerin: Alone and Combined

The aim of this work was to study the anti-Candida activity of lidocaine and nitroglycerin alone and in combination. Ten Candida strains were included, corresponding to 1 collection type strain (ATCC 10231) and 9 clinical isolates: 4 C. albicans, 2 C. glabrata, 1 C. tropicalis, 1 C. krusei, and 1 C. parapsilosis. The CLSI reference M27-A3 micromethod was used to determine the anti-Candida activity of the drugs alone; minimal inhibitory and lethal concentrations were determined. The classic checkboard technique was used to determine the activity of combined drugs. Lidocaine fungicidal effect was dosedependent. Nitroglycerin exhibited a higher effect. The drugs combination resulted in a reduction of the inhibitory concentration, corresponding to an additive effect. In conclusion, both drugs exhibited an interesting anti-Candida activity. The combination of lidocaine with nitroglycerin was shown to have an additive effect against Candida spp., predicting the interest to include, in the future, these drugs in a new delivery system for the treatment of mucocutaneous candidosis

Effect of Levels of Self-Regulation and Situational Stress on Achievement Emotions in Undergraduate Students: Class, Study and Testing

Achievement emotions constitute one important variable among the many variables of students’ learning. The aim of this research was to analyze the differential effect of university students’ levels of self-regulation (1 = low, 2 = medium and 3 = high), and of their level of perceived stress in three academic situations (1 = class, 2 = study time and 3 = testing), on the type of achievement emotionality they experience (positive and negative emotions). The following hypotheses were established: (1) a higher level of student self-regulation would be accompanied by higher levels of positive emotionality and lower levels of negative emotionality and (2) a higher level of situational stress would predispose higher levels of negative emotionality and lower levels of positive emotionality. A total of 520 university students completed three self-reports with validated inventories. Descriptive, correlational, and structural prediction analyses (SEM) were performed, as well as 3 × 3 ANOVAs, under an ex post facto design by selection. The results showed overall fulfillment of the hypotheses, except for a few specific emotions. Implications for prevention and psychoeducational guidance in the sphere of university education are discussed.Spanish Government PGC2018-094672-B-I00European Social Fund (ESF)University of Almeria, Spain UAL18-SEJ-DO31-A-FEDE