Estrategia de promoción de los atractivos culturales del municipio de Palacagüina durante el II semestre del año 2012.

La presente investigación se desarrolló en el municipio de Palacagüina, situado al norte de Nicaragua Palacagüina pertenece al departamento de Madriz, ubicado a 193 Km de la capital Managua y a 19 Km de Somoto. El municipio cuenta con un gran potencial para el desarrollo del turismo cultural, por su antigüedad y la herencia que existe desde épocas precolombinas y coloniales. Sin embargo la población desconoce el potencial turístico del municipio y no es considerado un polo de atracción turística. Sus atractivos culturales no están documentados y no cuentan con suficiente publicidad para dar a conocer estos atractivos y competir tanto a nivel nacional como internacional. Para la realización del presente trabajo: caracterizamos los principales atractivos culturales, clasificándolos en tangibles e intangibles. Determinamos el nivel de aceptación que tendría una revista que reúna esta información a acerca de estos atractivos, como una estrategia para promoverlos y dar a conocer información relevante, debido a que la actualmente existente está dispersa o incompleta. De esta manera se documentarían los principales atractivos culturales con que cuenta el municipio y se contribuiría a la sensibilización de la población. También como parte de nuestra estrategia de promoción creamos una página en facebook, la red social que usualmente se frecuenta en el país, con el fin de sensibilizara la población, principalmente al público más joven y hacer que se interesen más en este tema. También este permitirá atraer a una mayor cantidad de turistas tanto nacionales como internacionales. Estamos conscientes de que esto no es suficiente para rescatar y promover el patrimonio cultural, pero esperamos que nuestro trabajo de la pauta para futuras investigaciones en este tema, que permitan que la población esté informada y valore el patrimonio cultural que el municipio pose

AC mains synchronization loop for precalculated-based PFC converters using the output voltage measure

Common implementations of power factor correction include sensors for the input and output voltages and the input current. Many alternatives have been considered to reduce the number of sensors, especially the current sensor. One strategy is to precalculate the duty cycles that must be applied to every ac main, so the system only needs to synchronize them with the input voltage, and include a simple output voltage loop. The main problem with this approach is the sensibility to any synchronization error, because the input current is not measured, so its evolution is not continuously corrected. This paper shows how the synchronization error alters the current and the power factor, and it proposes several methods to detect and correct this error. All methods use the output voltage ADC, which is already used to control the output voltage, so the cost of the system is not increased. This technique can also be applied to any current sensorless PFC converter, because they are usually affected by leading or lagging currents, so the synchronization can be modified to reduce these effects. Results show that the implementation of this synchronization loop keeps a high-power factor under a wide synchronization error range, while the added logic is not significant.This research was funded by Spanish Ministerio de Economía y Competitividad grant number TEC2013-43017-R

Evaluation of the different numerical formats for HIL models of power converters after the adoption of VHDL-2008 by xilinx

Hardware in the loop is a widely used technique in power electronics, allowing to test and debug in real time (RT) at a low cost. In this context, field-programmable gate arrays (FPGAs) play an important role due to the high-speed requirements of RT simulations, in which area optimization is also crucial. Both characteristics, area and speed, are affected by the numerical formats (NFs) and their rounding modes. Regarding FPGAs, Xilinx is one of the largest manufacturers in the world, offering Vivado as its main design suite, but it was not until the release of Vivado 2020.2 that support for the IEEE NF libraries of VHDL-2008 was included. This work presents an exhaustive evaluation of the performance of Vivado 2020.2 in terms of area and speed using the native IEEE libraries of VHDL-2008 regarding NF. Results show that even though fixed-point NFs optimize area and speed, if a user prefers the use of floating-point NFs, with this new release, it can be synthesized—which could not be done in previous versions of Vivado. Although support for the native IEEE libraries of VHDL-2008 was included in Vivado 2020.2, it still lacks some issues regarding NF conversion during synthesis while support for simulation is not yet includedThis research received no external fundin

Routing Topologies of Wireless Sensor Networks for Health Monitoring of a Cultural Heritage Site

This paper provides a performance evaluation of tree and mesh routing topologies of wireless sensor networks (WSNs) in a cultural heritage site. The historical site selected was San Juan Bautista church in Talamanca de Jarama (Madrid, Spain). We report the preliminary analysis required to study the effects of heating in this historical location using WSNs to monitor the temperature and humidity conditions during periods of weeks. To test which routing topology was better for this kind of application, the WSNs were first deployed on the upper floor of the CAEND institute in Arganda del Rey simulating the church deployment, but in the former scenario there was no direct line of sight between the WSN elements. Two parameters were selected to evaluate the performance of the routing topologies of WSNs: the percentage of received messages and the lifetime of the wireless sensor network. To analyze in more detail which topology gave the best performance, other communication parameters were also measured. The tree topology used was the collection tree protocol and the mesh topology was the XMESH provided by MEMSIC (Andover, MA, USA). For the scenarios presented in this paper, it can be concluded that the tree topology lost fewer messages than the mesh topology.The Spanish Ministry of Economy and Competitiveness supported this research under grant numbers BIA2009-14395-C04-01 and TEC2012-38402-C04-03. The present study was also funded under project CGL2010-19554. S. Aparicio benefited from funding provided by the Spanish National Research Council (CSIC) through its Post-graduate Studies Council’s post-doctoral specialisation programme (JAE-Doc). Researcher Martínez-Garrido’s was supported by an International Programme for Recruiting Talent (PICATA) predoctoral fellowship awarded by the Moncloa Campus of International Excellence (UPM-UCM, CSIC). J. Ranz benefited from a FPI grant BES-2010-038826 of the Ministry of Education, Culture and Sports. We acknowledge support by the CSIC Open Access Publication Initiative through its Unit of Information Resources for Research (URICI

Acute Effects of Muscular Fatigue on Vertical Jump Performance in Acrobatic Gymnasts, Evaluated by Instrumented Insoles: A Pilot Study

The study of fatigue during training is becoming a very useful tool to avoid possible injuries not only during the training sessions but also during recovery time. Many researches have proved that concepts such as muscular fatigue and postactivation potentiation have a close relationship. With this aim, vertical jump can provide a very important information that can help to analyze the muscular fatigue that happened during this type of activity, mainly if the monitoring system is able to measure jumping parameters during their regular training session in their natural training environment. This study was performed with instrumented insoles called ECnsole. These insoles were tested with a group of twelve volunteers. In a tumbling surface, the participants performed a jumping protocol in three conditions: rest, fatigue-induced, and recovery. Using these validated insoles, the acrobatic gymnasts showed an inability to use the stretch-shortening cycle for improving vertical jumping performance after fatigue condition, although no deterioration of jump performance was found.Junta de Andalucía European Commission P10-TIC5997European Commissio

Calibration of semi-analytic models of galaxy formation using Particle Swarm Optimization

We present a fast and accurate method to select an optimal set of parameters in semi-analytic models of galaxy formation and evolution (SAMs). Our approach compares the results of a model against a set of observables applying a stochastic technique called Particle Swarm Optimization (PSO), a self-learning algorithm for localizing regions of maximum likelihood in multidimensional spaces that outperforms traditional sampling methods in terms of computational cost. We apply the PSO technique to the SAG semi-analytic model combined with merger trees extracted from a standard $\Lambda$CDM N-body simulation. The calibration is performed using a combination of observed galaxy properties as constraints, including the local stellar mass function and the black hole to bulge mass relation. We test the ability of the PSO algorithm to find the best set of free parameters of the model by comparing the results with those obtained using a MCMC exploration. Both methods find the same maximum likelihood region, however the PSO method requires one order of magnitude less evaluations. This new approach allows a fast estimation of the best-fitting parameter set in multidimensional spaces, providing a practical tool to test the consequences of including other astrophysical processes in SAMs.Comment: 11 pages, 4 figures, 1 table. Accepted for publication in ApJ. Comments are welcom

Virtual reality and augmented reality as strategies for teaching social skills to individuals with intellectual disability: a systematic review

Virtual reality (VR) and augmented reality (AR) programs have proliferated significantly in recent years and they are finding their way into different educational and therapeutic purposes. This systematic review aims at analyzing the virtual reality and augmented reality programs designed to promote the development of social skills in individuals with intellectual disability. Searches were carried out in the Scopus, Science Direct, Springer and Web of Science databases in the period from 2005 to 2020. A total of six articles met the inclusion criteria. A descriptive data analysis was performed. The results show that the clinical profile of the individuals who participated in the interventions is diverse. It can be concluded that there is some scientific evidence that points to the usefulness of VR and AR in the development of intervention programs to improve the social skills of individuals diagnosed with developmental deficits. However, it is necessary to acknowledge methodological limitations such as the lack of control groups, follow-up measures and of generalization of the resultsAgencia Nacional de Investigación e Innovació

Rethinking the Neural Basis of Prosody and Non-literal Language: Spared Pragmatics and Cognitive Compensation in a Bilingual With Extensive Right-Hemisphere Damage

Above and beyond the critical contributions of left perisylvian regions to language, the neural networks supporting pragmatic aspects of verbal communication in native and non-native languages (L1s and L2, respectively) have often been ascribed to the right hemisphere (RH). However, several reports have shown that left-hemisphere activity associated with pragmatic domains (e.g., prosody, indirect speech, figurative language) is comparable to or even greater than that observed in the RH, challenging the proposed putative role of the latter for relevant domains. Against this background, we report on an adult bilingual patient showing preservation of pragmatic verbal skills in both languages (L1: Spanish, L2: English) despite bilateral damage mainly focused on the RH. After two strokes, the patient sustained lesions in several regions previously implicated in pragmatic functions (vast portions of the right fronto-insulo-temporal cortices, the bilateral amygdalae and insular cortices, and the left putamen). Yet, comparison of linguistic and pragmatic skills with matched controls revealed spared performance on multiple relevant tasks in both her L1 and L2. Despite mild difficulties in some aspects of L2 prosody, she showed no deficits in comprehending metaphors and idioms, or understanding indirect speech acts in either language. Basic verbal skills were also preserved in both languages, including verbal auditory discrimination, repetition of words and pseudo-words, cognate processing, grammaticality judgments, equivalent recognition, and word and sentence translation. Taken together, the evidence shows that multiple functions of verbal communication can be widely spared despite extensive damage to the RH, and that claims for a putative relation between pragmatics and the RH may have been overemphasized in the monolingual and bilingual literature. We further discuss the case in light of previous reports of pragmatic and linguistic deficits following brain lesions and address its relation to cognitive compensation in bilingual patients

HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs

HuR/ELAVL1 is an RNA-binding protein involved in differentiation and stress response that acts primarily by stabilizing messenger RNA (mRNA) targets. HuR comprises three RNA recognition motifs (RRMs) where the structure and RNA binding of RRM3 and of full-length HuR remain poorly understood. Here, we report crystal structures of RRM3 free and bound to cognate RNAs. Our structural, NMR and biochemical data show that RRM3 mediates canonical RNA interactions and reveal molecular details of a dimerization interface localized on the -helical face of RRM3. NMR and SAXS analyses indicate that the three RRMs in full-length HuR are flexibly connected in the absence of RNA, while they adopt a more compact arrangement when bound to RNA. Based on these data and crystal structures of tandem RRM1,2- RNA and our RRM3-RNA complexes, we present a structural model of RNA recognition involving all three RRM domains of full-length HuR. Mutational analysis demonstrates that RRM3 dimerization and RNA binding is required for functional activity of fulllength HuR in vitro and to regulate target mRNAs levels in human cells, thus providing a fine-tuning for HuR activity in vivo.Peer reviewe

Whole genome sequencing and de novo assembly of Staphylococcus pseudintermedius: a pangenome approach to unravelling pathogenesis of canine pyoderma

Background Staphylococcus pseudintermedius is the main aetiological agent of canine pyoderma. Whole genome sequencing is the most comprehensive way of obtaining relevant genomic information about micro-organisms. Hypothesis/Objectives Oxford Nanopore technology enables quality sequencing and de novo assembly of the whole genome of S. pseudintermedius. Whole genome analysis of S. pseudintermedius may help to better understand the pathogenesis of canine pyodermas. Methods and materials Twenty-two strains of S. pseudintermedius isolated from the skin of five healthy dogs and 33 strains isolated from skin of 33 dogs with pyoderma were analysed. DNA was extracted and sequenced using Oxford Nanopore MinION, a new technology that delivers longer reads in a hand-held device. The pangenome was analysed and visualised with Anvi’o 6.1. Results Nanopore technology allowed the sequencing and de novo assembly of the genomes of 55 S. pseudintermedius strains isolated from healthy dogs and from dogs with pyoderma. The average genome size of S. pseudintermedius was 2.62 Mbp, with 48% being core genome. Pyoderma isolates contained a higher number of antimicrobial resistance genes, yet the total number of virulence factors genes did not change between isolates from healthy dogs and from dogs with pyoderma. Genomes of meticillin-resistant S. pseudintermedius (MRSP) strains were larger than those of meticillin-susceptible (MSSP) strains (2.80 Mbp versus 2.59 Mbp), as a consequence of a greater presence of antimicrobial resistance genes, phages and prophages. Conclusions and clinical importance This technique allows much more precise and easier characterisation of canine S. pseudintermedius populations and may lead to a better understanding of the pathogenesis of canine pyodermas.info:eu-repo/semantics/publishedVersio