38 research outputs found

    EELISA Credential: The Recognition Of Commitment And Impact In The Addressing Of Societal Challenges In The EELISA Alliance

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    EELISA Credential is a unique recognition process provided to EELISA students, professional and alumni who are part of the mission-driven EELISA communities and reflects the commitment and impact level achieved in the addressing of a societal challenge. The EELISA Credential is an individual, progressive environment on which students collect badges. These badges are acquired after verifying the achievement of an educational outcome level after participating in community\u27s educational activities. A badge represents the unit of learning acquisition and impact that corresponds to an educational outcome. It is reflected in the EELISA Credential which itself refers to an impact level and a Sustainable Development Goal (SDG). The impact level represents the badge measurement scale. In the EELISA Credential, there are 5 levels of impact (discovery, knowledge, engagement, action, transformation) that correspond to learning objectives relative to SDGs. The education activities proposed by EELISA Communities are defined around a societal challenge defined by a problem owner (faculty, students, local communities). Each activity is centered in 1 or 2 SDGs, and recognizes a maximum of 4 badges. Through the involvement in the activities of EELISA Communities, students enrich their EELISA Credential in areas addressing Sustainable Developments Goals (SDGs), progressively improving their capacity for understanding, action and transformation. In this practice paper, we will present the requirements for activities to be part of the EELISA Credential, representative and successful activities, the Quality Assurance system, the lessons learnt in the process of implementing the credential and how EELISA Credential will evolve in the future

    Análisis de una cuenca mio-pliocena relacionada a un ambiente volcánico: la cuenca Livitaca, Cusco

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    Como parte de los estudios realizados por el INGEMMET en la actualización de la Carta Geológica Nacional a escala 1/50000, en la zona de Livitaca se pudieron reconocer unidades volcanosedimentarias, descritas anteriormente por Mendívil & Dávila (1994) y Manrique (1992), que ponen en evidencia la existencia de sedimentos lacustres desarrollados en un ambiente volcánico, la cual hemos denominado: Cuenca Livitaca. Esta cuenca se encuentra en la Cordillera Occidental Sur del Perú, en el distrito de Livitaca, departamento del Cusco, y cubre un área aproximada de 32 km2. El cartografiado geológico del lugar y el levantamiento de columnas estratigráficas han permitido reconocer y estudiar esta cuenca, y así, poder determinar su evolución sedimentaria y paleogeográfica

    Micropropagation of four varieties of cassava (manihot sculenta crantz) with export and industrial potential in the Dominican Republic

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    Cassava (Manihot sculenta Crantz) has been a source of carbohydrates for low-income sectors of the population worldwide. Cassava is implicit in food security and sovereignty. The limitations of this crop to produce it are the lack of healthy material for planting and low yield levels. Cuttings from conventional cassava plantings are infested with pathogens and these are difficult to eliminate with existing procedures. This affects growth and yield. The massive in vitro multiplication of cassava contributes to the food security of Dominicans and the recovery of export markets. In vitro cassava plants were obtained to supply producers with high quality and yield varieties. In addition to being used in agro-industry, strengthening exports and satisfying the demand for material, it is important that the extraction of healthy material exceeds the traditional supply. For this reason, in vitro culture techniques are playing an important role in the maintenance of collections, sanitation and rejuvenation of the material whose yields are tripled when using in vitro cassava plants

    Persistence of COVID-19 Symptoms after Recovery in Mexican Population

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    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease (COVID-19), a highly contagious infectious disease that has caused many deaths worldwide. Despite global efforts, it continues to cause great losses, and leaving multiple unknowns that we must resolve in order to face the pandemic more effectively. One of the questions that has arisen recently is what happens, after recovering from COVID-19. For this reason, the objective of this study is to identify the risk of presenting persistent symptoms in recovered from COVID-19. This case-control study was conducted in one state of Mexico. Initially the data were obtained from the participants, through a questionnaire about symptoms that they had at the moment of the interview. Initially were captured the collected data, to make a dataset. After the pre-processed using the R project tool to eliminate outliers or missing data. Obtained finally a total of 219 participants, 141 recovered and 78 controls. It was used confidence level of 90% and a margin of error of 7%. From results it was obtained that all symptoms have an associated risk in those recovered. The relative risk of the selected symptoms in the recovered patients goes from 3 to 22 times, being infinite for the case of dyspnea, due to the fact that there is no control that presents this symptom at the moment of the interview, followed by the nausea and the anosmia with a RR of 8.5. Therefore, public health strategies must be rethought, to treat or rehabilitate, avoiding chronic problems in patients recovered from COVID-19

    Tecnologías de la información y de las comunicaciones aplicadas a problemas de agricultura regional

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    Se presenta una línea de I+D de gran interés regional, aplicada al problema de racionalización y uso adecuado del agua para riego de cultivos en climas áridos. Los temas abordados son transversales a varias áreas, como programación, arquitectura de computadoras, investigación operativa, bases de datos y análisis de sistemas. Los problemas provienen de empresas del medio, que a su vez se benefician de los resultados obtenidos. Se debe notar que en los proyectos participan alumnos avanzados activamente, por lo que los desarrollos propuestos convergen en tesinas de grado de la Ingeniería en Sistemas de la UNdeC.Eje: Innovación en Sistemas de SoftwareRed de Universidades con Carreras en Informática (RedUNCI

    A crowdsourcing database for the copy-number variation of the spanish population

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    Background: Despite being a very common type of genetic variation, the distribution of copy-number variations (CNVs) in the population is still poorly understood. The knowledge of the genetic variability, especially at the level of the local population, is a critical factor for distinguishing pathogenic from non-pathogenic variation in the discovery of new disease variants. Results: Here, we present the SPAnish Copy Number Alterations Collaborative Server (SPACNACS), which currently contains copy number variation profiles obtained from more than 400 genomes and exomes of unrelated Spanish individuals. By means of a collaborative crowdsourcing effort whole genome and whole exome sequencing data, produced by local genomic projects and for other purposes, is continuously collected. Once checked both, the Spanish ancestry and the lack of kinship with other individuals in the SPACNACS, the CNVs are inferred for these sequences and they are used to populate the database. A web interface allows querying the database with different filters that include ICD10 upper categories. This allows discarding samples from the disease under study and obtaining pseudo-control CNV profiles from the local population. We also show here additional studies on the local impact of CNVs in some phenotypes and on pharmacogenomic variants. SPACNACS can be accessed at: http://csvs.clinbioinfosspa.es/spacnacs/. Conclusion: SPACNACS facilitates disease gene discovery by providing detailed information of the local variability of the population and exemplifies how to reuse genomic data produced for other purposes to build a local reference database.This work is supported by Grants PID2020-117979RB-I00 from the Spanish Ministry of Science and Innovation; by the Institute of Health Carlos III (project IMPaCT-Data, exp. IMP/00019, IMP/00009 and PI20/01305), co-funded by the European Union, European Regional Development Fund (ERDF, “A way to make Europe”)

    Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885

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    The authors wish to make the following corrections to this paper [...]

    Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study

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    (1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery

    Reperfusion treatment in acute ischaemic stroke due to cervical and cerebral artery dissection: results of a Spanish national multicentre study

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    Introducción: El ictus isquémico (II) por disección arterial cervicocerebral (DAC) es una entidad infrecuente y existen pocos datos sobre el uso de terapias de reperfusión como la fibrinólisis intravenosa y la trombectomía mecánica. Se analizó el uso de dichas terapias en pacientes con II por DAC y se comparó con aquellos pacientes reperfundidos con II por otras causas. Método: Estudio observacional retrospectivo multicéntrico de pacientes con II por DAC basado en el Registro Nacional de Ictus de la Sociedad Española de Neurología durante el periodo 2011-2019. Se realizaron análisis comparativos entre: a) pacientes con DAC tratados y no tratados con terapias de reperfusión y b) pacientes reperfundidos con II por DAC y pacientes reperfundidos con II por otras causas. Se incluyeron variables epidemiológicas, del ictus y resultados al alta y a los 3 meses. Resultados: Un total de 21.037 pacientes con II fueron incluidos; 223 (1%) fueron por DAC y 68 (30%) recibieron tratamiento de reperfusión. El uso de tratamientos de reperfusión fue menor en los casos de DAC de arteria vertebral y mayor en los casos de oclusión carotídea. Los pacientes con II por DAC reperfundidos respecto a aquellos con II reperfundidos por otras causas fueron más jóvenes, la trombectomía mecánica se utilizó más y la fibrinólisis intravenosa menos. Las complicaciones hemorrágicas, la mortalidad y la autonomía a los 3 meses fueron similares. Conclusiones: Las terapias de reperfusión se usan con frecuencia en los pacientes con II por DAC. Los resultados demuestran eficacia y seguridad y son equiparables a los pacientes tratados con terapias de reperfusión por II de otras causas.Introduction: Ischaemic stroke (IS) due to cervical and cerebral artery dissection (CAD) is a rare entity, and few data are available on the use of such reperfusion therapies as intravenous fibrinolysis and mechanical thrombectomy in these patients. We analysed the use of these treatments in patients with IS due to CAD and compared them against patients receiving reperfusion treatment for IS of other aetiologies. Method: We conducted an observational, retrospective, multicentre study of patients with IS due to CAD recorded in the National Stroke Registry of the Spanish Society of Neurology during the period 2011-2019. Comparative analyses were performed between: a) patients with CAD treated and not treated with reperfusion therapies and b) patients treated with reperfusion for IS due to CAD and patients treated with reperfusion for IS due to other causes. Epidemiological data, stroke variables, and outcomes at discharge and at 3 months were included in the analysis. Results: The study included 21,037 patients with IS: 223 (1%) had IS due to CAD, of whom 68 (30%) received reperfusion treatment. Reperfusion treatments were used less frequently in cases of vertebral artery dissection and more frequently in patients with carotid artery occlusion. Compared to patients with IS due to other causes, patients with CAD were younger, more frequently underwent mechanicalthrombectomy, and less frequently received intravenous fibri nolysis. Rates of haemorrhagic complications, mortality, and independence at 3 months were similar in both groups. Conclusions: Reperfusion therapy is frequently used in patients with IS due to CAD. The outcomes of these patients demonstrate the efficacy and safety of reperfusion treatments, and are comparable to the outcomes of patients with IS due to other aetiologie

    Un discurrir en el hábitat más íntimo del ser [humano]

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    ¿Qué es una Casa? ¿Qué significa LA CASA? Resulta muy diferente definir LA CASA en términos de concepto que definirla en términos de significado. En la Psicología, se utilizan dos términos relacionados con cada objeto: significado y significante. El significado hace referencia al concepto en sí y, en ese sentido, una casa sería un lugar para habitar, es decir, “un techo encima de la cabeza”, en palabras del profesor mencionado por el editor de este libro. El significante, por su lado, hace referencia al sentido, a la representación mental, al símbolo, a la imagen, a la percepción que, de ese concepto, pueda construir cada persona y, en ese sentido, puede evocar otros conceptos como hogar, refugio, protección, unión, afecto, recuerdos, oportunidades, valores, sabores, olores, eventos, familia, pareja, realización, pasado, futuro, etc
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