La importancia del trabajo con la familia en la atención a menores extranjeros no acompañados. Un estudio piloto

Los movimientos de población desde zonas con graves problemas económicos o de seguridad a otras con una mayor garantía en la satisfacción de necesidades básicas es uno de los fenómenos de nuestra era. Las dificultades propias que acarrea el proceso de migración se ven aumentadas cuando hablamos de Menores Extranjeros No Acompañados. El presente estudio es un proyecto piloto en el que se realizó una intervención grupal focalizada en la familia con una muestra de 12 menores procedentes todos ellos de Marruecos. De cada participante se obtuvo una media pretest/postest en las variables depresión, autoestima, alexitimia y relación familiar. Los análisis estadísticos indicaron la existencia de diferencias significativas pretest-postest en cada una de las variables objeto de estudio, así como elevados tamaños del efecto. Las mejoras que señalan los resultados sugieren que la intervención con el colectivo MENA debe de tomar en cuenta a la familia de origen del menor.The migration of people from places with huge economical or security problems to areas with broader guarantees has become a relevant topic of our age. The difficulties of the migration process itself raise when the migrating subjects are underage non accompanied children. The present study wants to show the results obtained in a pilot project where 12 Moroccan minors took part in a group treatment focused on family. From each participant, pretest and posttest measures were obtained in variables such as depression, self steem, alexythimia and family relationship. The statistical analysis show significative pretest-postest differences on each studied variable, as well as high effect sizes. These results suggest that when working with non accompanied foreign children the family of origin of the minor is a relevant factor that must be taken into account

Genomic transformation and social organization during the Copper Age-Bronze Age transition in southern Iberia

The emerging Bronze Age (BA) of southeastern Iberia saw marked social changes. Late Copper Age (CA) settlements were abandoned in favor of hilltop sites, and collective graves were largely replaced by single or double burials with often distinctive grave goods indirectly reflecting a hierarchical social organization, as exemplified by the BA El Argar group. We explored this transition from a genomic viewpoint by tripling the amount of data available for this period. Concomitant with the rise of El Argar starting ∼2200 cal BCE, we observe a complete turnover of Y-chromosome lineages along with the arrival of steppe-related ancestry. This pattern is consistent with a founder effect in male lineages, supported by our finding that males shared more relatives at sites than females. However, simple two-source models do not find support in some El Argar groups, suggesting additional genetic contributions from the Mediterranean that could predate the BA.This work was supported by the Max Planck Society (V.V.-M. and W.H.); European Research Council (ERC) grant 771234—PALEoRIDER (W.H.); Spanish Ministry of Economy, Industry and Competitiveness project HAR2017-85962-P (C.O., C.R.-H., M.I.F., E.C.B., C.V.-F., V.L., R.M., and R.R.); AGAUR 2017SGR1044 (C.O., C.R.-H., M.I.F., E.C.B., C.V.-F., V.L., R.M., and R.R.); ICREA Academia program (R.R.); John Templeton Foundation grant 61220 (D.R.); and Paul Allen Family Foundation (D.R.). D.R. is an Investigator of the Howard Hughes Medical Institute

Genomic transformation and social organization during the Copper Age-Bronze Age transition in southern Iberia

[EN]The emerging Bronze Age (BA) of southeastern Iberia saw marked social changes. Late Copper Age (CA) settlements were abandoned in favor of hilltop sites, and collective graves were largely replaced by single or double burials with often distinctive grave goods indirectly reflecting a hierarchical social organization, as exemplified by the BA El Argar group. We explored this transition from a genomic viewpoint by tripling the amount of data available for this period. Concomitant with the rise of El Argar starting similar to 2200 cal BCE, we observe a complete turnover of Y-chromosome lineages along with the arrival of steppe-related ancestry. This pattern is consistent with a founder effect in male lineages, supported by our finding that males shared more relatives at sites than females. However, simple two-source models do not find support in some El Argar groups, suggesting additional genetic contributions from the Mediterranean that could predate the BA.This work was supported by the Max Planck Society (V.V.-M. and W.H.); European Research Council (ERC) grant 771234-PALEoRIDER (W. H.); Spanish Ministry of Economy, Industry and Competitiveness project HAR2017-85962-P (C.O., C.R.-H., M.I.F., E.C.B., C.V.-F., V.L., R.M., and R.R.); AGAUR 2017SGR1044 (C.O., C.R.-H., M.I.F., E. C.B., C.V.-F., V. L., R.M., and R.R.); ICREA Academia program (R.R.); John Templeton Foundation grant 61220 (D.R.); and Paul Allen Family Foundation (D.R.). D.R. is an Investigator of the Howard Hughes Medical Institute

Riesgo quirúrgico tras resección pulmonar anatómica en cirugía torácica. Modelo predictivo a partir de una base de datos nacional multicéntrica

Introduction: the aim of this study was to develop a surgical risk prediction model in patients undergoing anatomic lung resections from the registry of the Spanish Video-Assisted Thoracic Surgery Group (GEVATS). Methods: data were collected from 3,533 patients undergoing anatomic lung resection for any diagnosis between December 20, 2016 and March 20, 2018. We defined a combined outcome variable: death or Clavien Dindo grade IV complication at 90 days after surgery. Univariate and multivariate analyses were performed by logistic regression. Internal validation of the model was performed using resampling techniques. Results: the incidence of the outcome variable was 4.29% (95% CI 3.6-4.9). The variables remaining in the final logistic model were: age, sex, previous lung cancer resection, dyspnea (mMRC), right pneumonectomy, and ppo DLCO. The performance parameters of the model adjusted by resampling were: C-statistic 0.712 (95% CI 0.648-0.750), Brier score 0.042 and bootstrap shrinkage 0.854. Conclusions: the risk prediction model obtained from the GEVATS database is a simple, valid, and reliable model that is a useful tool for establishing the risk of a patient undergoing anatomic lung resection

Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort

Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observed in prediction models is still high. Therefore, new risk factors need to be identified in order to better predict the risk of CKD in the population. Here, we analyzed the genetic association of 79 SNPs of proteins associated with mineral metabolism disturbances with CKD in a cohort that includes 2, 445 CKD cases and 559 controls. Genotyping was performed with matrix assisted laser desorption ionizationtime of flight mass spectrometry. We used logistic regression models considering different genetic inheritance models to assess the association of the SNPs with the prevalence of CKD, adjusting for known risk factors. Eight SNPs (rs1126616, rs35068180, rs2238135, rs1800247, rs385564, rs4236, rs2248359, and rs1564858) were associated with CKD even after adjusting by sex, age and race. A model containing five of these SNPs (rs1126616, rs35068180, rs1800247, rs4236, and rs2248359), diabetes and hypertension showed better performance than models considering only clinical risk factors, significantly increasing the area under the curve of the model without polymorphisms. Furthermore, one of the SNPs (the rs2248359) showed an interaction with hypertension, being the risk genotype affecting only hypertensive patients. We conclude that 5 SNPs related to proteins implicated in mineral metabolism disturbances (Osteopontin, osteocalcin, matrix gla protein, matrix metalloprotease 3 and 24 hydroxylase) are associated to an increased risk of suffering CKD

Ibilgailu elektrikoen potentzia-bihurgailuen hozte-metodoak

Ibilgailu elektrikoari loturiko potentzia-bihurgailuetan, korronte-dentsitate handitan (500 A ingurukoak) lan egiten duten IGBT transistoreak eta diodoak erabiltzen dira. Korronte altuak direla eta, handitu egiten dira gailu erdieroale horietan gertatzen diren kommutazio- eta kondukzio-galerak, eta ondorioz, potentzia-erdieroaleak berotu egiten dira. Moduluen efizientzia eta fidagarritasuna ziurtatzeko, beharrezkoa da hozte-sistema eraginkor eta egoki bat aukeratzea. Artikulu honetan, potentzia-bihurgailuen moduluen hozte-metodoak berrikusi eta eztabaidatuko dira.

Status and advances in Electric Vehicle’s power modules packaging technologies

Articulo Congreso PCIM 2016The technology used in the design of the high power density Electric Vehicle (EV) power inverters packaging (power modules electrical, thermal and thermo-mechanical properties) directly affect the power inverter performance, cost, reliability, efficiency and power density. In this paper the technical trends and advances in EV power module packaging technologies will be reviewed and actual manufactured automotive power modules will be evaluated. Advantages and disadvantages of such modules will be highlighted.This work has been carried out inside the Research and Education Unit UFI11/16 of the UPV/EHU and supported by the Department of Education, Universities and Research of the Basque Government within the fund for research groups of the Basque university system IT394-10 and by the University of the Basque Country. This work has been supported by the Ministerio de Economía y Competitividad of Spain within the project DPI2014-53685-C2-2-R and FEDER funds

Estado actual y avances en las tecnologías de ensamblado de los módulos de potencia asociados al vehículo eléctrico

Ponencia presentada a XXIII Seminario Anual de Automática, Electrónica Industrial e Instrumentación (SAAEI'16), Elche, 6-8 de julio de 2016Las tecnologías de ensamblado empleadas en el diseño de los módulos de potencia son de suma importancia y afectan directamente al rendimiento, fiabilidad, eficiencia y coste del inversor. El presente artículo trata de analizar y comparar las tecnologías de ensamblado empleadas actualmente en el diseño de módulos de potencia asociados al VE (Vehículo Eléctrico). En este sentido, se realiza una comparativa y se analizan las ventajas y desventajas que presentan los inversores de potencia empleados actualmente en los VE.El trabajo descrito en esta publicación ha sido generado en la Unidad de Formación e Investigación UFI11/16 financiada por la UPV/EHU y patrocinado por el Departamento de Educación, Universidades e Investigación del Gobierno Vasco en base a las ayudas para apoyar las actividades de grupos de investigación del sistema universitario vasco IT394-10. El trabajo ha sido financiado por el Ministerio de Economía y Competitividad a través del proyecto de investigación DPI2014-53685-C2-2-R y los fondos FEDER. Asimismo, ha sido financiado por el Gobierno Vasco a través del proyecto de investigación KT4TRANS del programa ELKARTEK (KK-2015/00047)

Mitochondrial DNA copy number differentiates the Leber's hereditary optic neuropathy affected individuals from the unaffected mutation carriers

[No abstract available