Dinuclear Co(II)‑Muconate Complex Displaying Distorted‑TrigonalPrismatic Geometry, 2D Supramolecular Array and Weak Antiferromagnetism

Influence of the 2D supramolecular array in the distorted trigonal prismatic geometry of a dinuclear Co(II)-muconate complex exhibiting weak antiferromagnetic exchange.Dinuclear complex [ Co2(H2O)4(dmb)2(muc)][muc] (1) (muc = muconate; dmb = 5,5′-dimethyl-2,2′-bipyridine), was obtained by self-assembly solution reaction, under ambient conditions, and it was structurally characterized by elemental analysis, IR spectroscopy and single crystal X-ray diffraction. The complex 1 crystallizes in the monoclinic system in the C2/c space group. Noticeably, the six-coordinated Co(II) centers display a distorted-trigonal prismatic configuration. This uncommon coordination geometry is attained due to the hydrogen bonding interactions of the crystalline structure of 1, yielding thus a 2D supramolecular array. Magnetic properties measurements reveal that metaprism 1 exhibits weak antiferromagnetic ordering with θ(C-W) = -14.4 K and an E2 = 0.032 cm− 1 accordingly to Curie–Weiss model and Rueff phenomenological approach, respectively.Universidad Autónoma del Estado de México Universidad Nacional Autónoma de Méxic

Morphology and Material Composition of the Mouthparts of Stromatium unicolor Olivier 1795 (Coleoptera: Cerambycidae) for Bionic Application

The novelty of this study is the deep analysis of the morphologic, geometric and mechanical performance of longhorn beetle larvae mouthparts. Furthermore, a metal nano identification of jaw reinforced parts was made. Background and Objectives: Analysis of insect mechanical properties has shown an important application in the develop of bionic technologies such as new materials, industrial machines and structural concepts. This study aims to determine the mechanical and geometric properties of longhorn beetle (Stromatium unicolor Olivier 1795) larvae mouthparts to improve the development of innovative cutting tools. In addition, this study obtains a nano identification of metals in the cuticle of the mouthparts, which will enable the development of new nontoxic and sustainable preservation agents against xylophagous insects based on nanoparticles. Materials and Methods: five third-larval-stage samples of Stromatium unicolor were used to study its mandible morphologic, geometric and mechanical properties. To this end, mouthparts were analyzed by several microscopic techniques using a scanning electron microscope, a stereomicroscope and an optical microscope. Composition analysis was performed using with two Analytical-Inca X-ray detectors, dispersive energy spectroscopy and dispersive wavelength spectroscopy. Results: The main geometric parameters of the insect jaw are the edge angle (β = 77.3°), maximum path depth of the insect (120 μm), length (800 µm) and mouthpart movement, which were identified and measured. The chemical analysis results of the jaw tissues shows the presence of zinc and manganese. Conclusions: The geometry and angles of the mouthparts can be applied in the fabrication of bionic self-sharpening cutting tools. Molecular compounds that form the reinforcing elements in the jaws can be used to develop wood preservatives based on nanometals and metal absorption and metabolism inhibitor

DISEÑO DE UN SISTEMA WEB QUE PERMITE LA GESTIÓN DEL CONOCIMIENTO

Este artículo tiene como objetivo presentar el diseño de Sinergia, un sistema web que permite la gestión del conocimiento y tiene como objetivo fomentar y registrar las buenas prácticas y experiencias que cada colaborador ha tenido dentro de las actividades o procesos que se manejan en el día a día durante el proceso de investigación formativa que se da en la Licenciatura en Informática para así aportar al mejoramiento y contribuir con su permanencia y crecimiento. Soportando el diseño de este sistema web dentro de la cultura organizacional con una visión centrada en los colaboradores del área de Investigación y sus procesos

Syntheses and Crystal Structures of Mn(II), Ni(II) and Cu(II) Coordination Compounds Assembled by Maleato and Dimethyl-2,2′-bipyridines

We have reported the synthesis and crystalline molecular and supramolecular structures of three novel complexes of Mn(II), Ni(II) and Cu(II), 1–3, respectively, employing maleato and dimethyl-2,2′-bipyridines as ligands. 1 is a 1D polymer, where the Mn centers are six-coordinated in a distorted octahedral geometry. 2 is a dinuclear complex, generated by supramolecular interactions, where Ni ions are six-coordinated in a distorted octahedral geometry. 3 is a dinuclear complex with five-coordinated Cu ions having a slightly-distorted square pyramidal geometry. Furthermore, solid-state assemblies on the structures of 1–3 generate supramolecular frameworks, mainly through hydrogen bonding: 2D for complexes 1 and 2, and 3D for complex 3. Thus, the versatility in the different coordination modes of maleato ligand: chelate bidentate and bridging- monodentate for polymer 1, monodentate for complex 2 and chelate bidentate for complex 3; has been evidenced by generating divergent coordination compounds of three different transition metals using facile self-assembly reactionsThree complexes: {[Mn(H2O)(mal)(5dmb)·H2O}n] (1); [ Ni2(H2O)6(mal)2(4dmb)2]·3H2O (2); [ Cu2(mal)2(4dmb)2]·3H2O (3); where mal = maleato, 4dmb = 4,4′-dimethyl-2,2′-bipyridine, and 5dmb = 5,5′-dimethyl-2,2′-bipyridine; have been synthesized, using self-assembly solution reactions at ambient conditions. Crystallographic studies show that 1 crystallizes in an orthorhombic system, space group Pna21, with a = 17.4067(4) Å, b = 11.9672(2) Å, c = 8.2075(2) Å; V = 1709.70(6) Å3. Complex 2 has a monoclinic system, space group C2/c, with a = 21.206(8) Å, b = 7.523(3) Å, c = 25.399(10) Å; β = 109.755(8)°; V = 3813(2) Å3. Complex 3 crystallizes in a monoclinic system, space group C2/c, with a = 14.6976(12) Å, b = 11.3849(10) Å, c = 22.1638(18) Å; β = 101.2998(17)°; V = 3636.8(5) Å3. Complex 1 is a one-dimensional (1D) polymer, where the Mn centers are six-coordinated in a distorted octahedral geometry. 2 is a dinuclear complex, generated by supramolecular interactions, where Ni ions are six-coordinated in a distorted octahedral geometry. 3 is a dinuclear complex with five-coordinated Cu ions having a distorted square pyramidal geometry. All three complexes exhibit hydrogen bonding interactions, which generate 2D supramolecular structures in 1 and 2, whereas in complex 3 a 3D supramolecular array is formed. These novel complexes prove that the self-assembly of a dicarboxylate ligand (mal) with three different first-row transition metals, can afford coordination compounds with diverse structural characteristics and dimensionality, which can be attributed to the different ligand coordination modes and the coordination properties of the employed metals

Emociones y extrema derecha: el caso de VOX en Andalucía

España ya no es la excepción del contexto europeo. La incorporación de VOX al sistema de partidos andaluz, primero, y después al español, representa el inicio de una nueva etapa política. Más allá de una lectura simplista sobre la extrema derecha, el objetivo de este artículo es establecer un perfil emocional que caracterice al votante de dicha formación política en contraposición a las restantes, y el de arrojar luz sobre las claves de la aparición de esta nueva fuerza política. Con la finalidad de analizar su irrupción, el presente artículo pretende construir un modelo estructural (SEM) que describa y explique los impactos y efectos de cada uno de los elementos que han estructurado el comportamiento político y la elección de voto a VOX.S

Acoustic detection and localisation system for Hylotrupes bajulus L. larvae using a MEMS microphone array

Producción CientíficaA novel system for acoustic detection of the presence of xylophagous insect larvae inside structural timber beams is presented. It is based on an extensive array of MEMS microphones that allows the acoustic detection and localisation of the larvae when they are active. In a first phase, the activity of the larvae is continuously detected by means of frequency filtering and a sliding energy estimator, and after that, a set of short-duration segmented signals is generated, which obtains the spatial localisation of the larvae, by means of a shaping algorithm based on delay-sum beamforming techniques. The tests carried out demonstrate that it is possible to detect and locate multiple larvae of Hylotrupes bajulus L. inside structural-sized pieces of wood of Pinus syilvestris L., as well as their internal trajectory. In the future, the system could address the identification of the specific type of xylophage responsible for the deterioration by using machine learning or equivalent techniques, based on the temporal and frequency information of the detected sound events. The aim of this work is to control unintentional infestions in the international timber trade, in the assembly and the use of infested timber and, in all cases, to be able to carry out selective, targeted and localised treatments and to verify their success.Junta de Castilla y León - UE-FEDER (VA228P20

1,4-Cyclohexanedicarboxylato-bridged cobalt coordination polymers: Synthesis, crystal structures and magnetic properties

1,4-Cyclohexanedicarboxylato-bridged cobalt coordination polymers: Synthesis, crystal structures and magnetic propertiesThree coordination polymers have been synthesized, using self-assembly solution reactions at ambient conditions, combining Co(II) ion with 1,4-ciclohexanedicarboxylic acid, in the presence of 1,10-phenantrolione and two different 2,20-bipyridines, as co-ligands: [Co(H2O)(cdc)(phen)]n (1); {[Co(H2O)(cdc)(4dmb)] 2H2O}n (2); {[Co(H2O)(cdc)(5dmb)] 3H2O}n (3), where cdc = e,a-cis-1,4-ciclohexanedicarboxylato, phen = 1,10-phenantroline, 4dmb = 4,40-dimethyl-2,20-bipyridine, and 5dmb = 5,50-dimethyl-2,20-bipyridine. Crystallographic studies show that these compounds have one-dimensional (1D) structures; Co(II) in 1–3 is six-coordinated with a distorted-octahedral coordination sphere. Complexes 2 and 3 exhibit a novel bridging motif of the cdc ligand in its equatorial, axial cis configuration. In addition, the solid-state self-assembly of the polymeric structure of 1 gives rise to a 2D supramolecular framework, mainly through hydrogen bonding. In contrast, complex 2 forms an infinite 1D supramolecular array, made of double Co ion rows bridged by hydrogen bonding interactions. Complex 3 generates an intricate 2D supramolecular framework also throughout hydrogen bonding. The thermal stabilities of the three coordination polymers were investigated. Magnetic properties measurements reveal that complexes 1–3 exhibit weak antiferromagnetic ordering with h(C-W) = 9.6, 5.8 and 7.5 K, and E2 = 0.51, 0.16 and 0.28 cm 1, accordingly to Curie-Weiss model and Rueff phenomenological approach, respectively

RELIGIOUS FREEDOM IN INDONESIA: Curious Cases of Dialogues, Fatwas and Laws

Sauropod dinosaurs include the largest terrestrial animals and are considered to have uninterrupted rapid rates of growth, which differs from their more basal relatives, which have a slower cyclical growth. Here we examine the bone microstructure of several sauropodo- morph dinosaurs, including basal taxa, as well as the more derived sauropods. Although our results agree that the plesiomorphic condition for Sauropodomorpha is cyclical growth dynamics, we found that the hypothesized dichotomy between the growth patterns of basal and more derived sauropodomorphs is not supported. Here, we show that sauropod-like growth dynamics of uninterrupted rapid growth also occurred in some basal sauropodo- morphs, and that some basal sauropods retained the plesiomorphic cyclical growth patterns. Among the sauropodomorpha it appears that the basal taxa exploited different growth strategies, but the more derived Eusauropoda successfully utilized rapid, uninterrupted growth strategies.Facultad de Ciencias Naturales y Muse

Methodology for the analysis of vulnerability to water watershed supplying climate variability

This research paper presents a methodology for the analysis of vulnerabi­lity of water supply sources with regional results (Popayan and Cajibío), considering the following points: 1) incorporation of relevant indicators of municipal water supply sources, 2) Local knowledge on perception, and identification of climate related problems, 3) mathematical procedures and adjust the algorithm for calculating the vulnerability and 4) coordination with territorial planning instruments. As a result, the vulnerability in the current scenario of the Rio Las Piedras subbasin (Popayán) is medium low (0.42) product generated by adaptive capacity developed synergistic processes between local actors; in contrast, the basin of the river Michicao (Cajibio) has a high average vulnerability (0.54) due to social dislocation, low institutional presence and zero environmental investment.Este artículo de investigación presenta una metodología para el análisis de vulnerabilidad de fuentes abastecedoras de agua con resultados regionales (Popayán y Cajibío), considerando los siguientes elementos: 1) Incorpora­ción de indicadores pertinentes para fuentes abastecedoras de acueductos municipales, 2) Saberes locales sobre percepción, clima e identificación de problemáticas relacionadas, 3) Procedimientos matemáticos y ajuste del algoritmo para calcular la vulnerabilidad y 4) articulación con instrumentos de planificación territorial. Como resultado, la vulnerabilidad en el escenario actual de la subcuenca río Las Piedras (Popayán) es medio baja (0,42), produc­to de la capacidad adaptativa generada por procesos sinérgicos desarrollados entre los actores locales; en contraste, la subcuenca del río Michicao (Cajibío) presenta una vulnerabilidad media alta (0,54), debido a la desarticulación social, baja presencia institucional y nula inversión ambiental

First reported double drug–drug interaction in a cancer renal patient under everolimus treatment: therapeutic drug monitoring and review of literature

Everolimus is an inhibitor of mammalian target of rapamycin (mTOR) used in both transplantation and cancer treatment (breast, renal and neuroendocrine). In transplantation, therapeutic drug monitoring (TDM) is recommended due to the potential drug-drug interactions with chronic medications, which can affect everolimus pharmacokinetics. In cancer treatment, everolimus is used at higher doses than in transplantation and without a systematic drug monitoring.We present a case report of a 72-year-old woman with epilepsy history to whom everolimus 10 mg QD was prescribed as third line of treatment for renal cell carcinoma (RCC). The potential drug interactions between everolimus and the patient's chronic medications, carbamazepine and phenytoin, are significant as both are known as strong inducers CYP3A4 metabolism, potentially leading to underexposure to everolimus.TDM of everolimus was recommended by the pharmacist. The literature suggests that a minimum plasma concentration (Cminss) of everolimus over 10 ng/ml is associated with better response to treatment and progression-free survival (PFS). The patient's everolimus dose had to be increased until 10 mg BID, and regular monitoring of everolimus levels showed an increase in Cminss from 3.7 ng/ml to 10.8 ng/ml.This case highlights the importance of checking for potential drug interactions and monitoring everolimus levels in patients on chronic medication, especially those with several inducers or inhibitors of CYP3A4 metabolism. TDM can help to ensure that patients are treated with their optimal dose, which can improve the effectiveness of the treatment or minimize the risk of toxicities