18,950 research outputs found
Determinants of tourism destination competitiveness in the countries most visited by international tourists: Proposal of a synthetic index
Tourism destination competitiveness is a multidimensional concept that is widely studied in the academic literature, but multiple factors make its measurement a difficult task. In this article, we design a synthetic index to rank the 80 countries that attract the majority of international tourists by level of tourism competitiveness. In order to do this, we use all of the simple variables included in the 2017 Travel & Tourism Competitiveness Index, proposing a new methodology for the construction of this synthetic index, which it solves the problems of aggregation of variables expressed in different measures, arbitrary weighting and duplicity of information; issues that remain unresolved by the TTCI. Likewise, we analyse the most influential dimensions in tourism competitiveness. Air transport infrastructures, cultural resources and ICT readiness are the key dimensions that explain the main disparities.Funding Agency
Spanish Ministry of Economy, Industry and Competitiveness
State Research Agency (SRA)
European Union (EU)
ECO2017-86822-Rinfo:eu-repo/semantics/publishedVersio
The determinants of pricing in pharmaceuticals : are U.S. prices really higher than those of Canada?
This paper studies price determination in pharmaceutical markets using data for 25 countries,
six years and a comprehensive list of products from the MIDAS IMS database. We show that
market power and the quality of the product has a significantly positive impact of prices. The
nationality of the producer appears to have a small and often insignificant impact on prices,
which suggests that countries which regulates prices have relatively little power to do it in a way
that advances narrow national interest. We produce a theoretical explanation for this
phenomenon based on the fact that low negotiated prices in a country would have a knock-on
effect in other markets, and is thus strongly resisted by producers. Another key finding is that
the U.S. has prices that are not significantly higher than those of countries with similar income
levels. This, together with the former observation on the effect of the nationality of producers
casts doubt on the ability of countries to pursue “free-riding" regulation
Variation of seed characteristic from natural and artificial selection in the genus Papaver
Papaveraceae is a mediterranean plant family with an important scientific, commercial and ethnobotanical interest. Includes wild species, which are distributed throughout the Spanish territory, as Papaver rhoeas, P. dubium, P. bracteatum, P. hybridum and the wild type of P. somniferum, which are representatives of the natural selection. The species with the greatest commercial interest is P. somniferum, whose management through improvement lines reflects the most profitable plant characteristics obtained by artificial selection: fast and vigorous growth, multiple flowers and big size capsules (1), traits that increase the production of morphine, codeine and thebaine among others opiates derived from the capsule leachate. Occasionally, some breeding lines of P. somniferum shown wild features, such as capsule dehiscence or extended germination time. Papaver becomes, thereby, an interesting plant genus to analyze the differential evolution experienced through natural and artificial selection. In this regard, previous studies reported that seed surface patter can be used in taxonomic classification of Papaveraceae family members (2). The main goal of this project was to characterize several seed traits variation among wild and cultivated samples. Seed size and shape was characterized using images analysis from macro-photography and the software ImageJ. Seed color, defined in the L, a*, b* color space, was recorded with an automatic colorimeter. Electron scanning microscopy (SEM) micrographs were used to study seed surface crosslinked patterns. Finally, confocal scanning microscopy allowed a preliminary approach to the internal seed tissue structure. The results shown that wild species seeds have deeper color than P. somniferum breeding lines but even among those it is possible to distinguish at least four main differentiated groups by color. Likewise, even if all breeded P. somniferum samples had larger seeds than wild species, probably as the results of artificial selection, there were clear variation among them. We discuss if the variations in these seed characteristics was the unintended result of the artificial trait breeding selection with agronomic interest.
References
* (1) Referencia general aquĂ
* (2) Referencia sobre caracteres de la superficie de la semilla como indicadores taxonĂłmicos
Funding
Authors thanks funding support from Alcaliber S.A. (OTRI-UMA-8.06/5.03.4280) and the University of Málaga to EMC, and Spanish Ministry of Enconomy and EU grant for AJMA (RYC-2011-08839).Universidad de Málaga. Campus de Excelencia Internacional AndalucĂa Tech
The Determinants of Pricing in Pharmaceuticals: Are U.S. Prices Really Higher than Those of Canada?
This paper studies price determination in pharmaceutical markets using data for 25 countries, six years and a comprehensive list of products from the MIDAS IMS database. We show that market power and the quality of the product has a significantly positive impact of prices. The nationality of the producer appears to have a small and often insignificant impact on prices, which suggests that countries which regulates prices have relatively little power to do it in a way that advances narrow national interest. We produce a theoretical explanation for this phenomenon based on the fact that low negotiated prices in a country would have a knock-on effect in other markets, and is thus strongly resisted by producers. Another key finding is that the U.S. has prices that are not significantly higher than those of countries with similar income levels. This, together with the former observation on the effect of the nationality of producers casts doubt on the ability of countries to pursPharmaceutical prices
The determinants of pricing in pharmaceuticals: Are U.S. prices really higher than those of Canada?
This paper studies price determination in pharmaceutical markets using data for 25 countries, six years and a comprehensive list of products from the MIDAS IMS database. We show that market power and the quality of the product has a significantly positive impact of prices. The nationality of the producer appears to have a small and often insignificant impact on prices, which suggests that countries which regulates prices have relatively little power to do it in a way that advances narrow national interest. We produce a theoretical explanation for this phenomenon based on the fact that low negotiated prices in a country would have a knock-on effect in other markets, and is thus strongly resisted by producers. Another key finding is that the U.S. has prices that are not significantly higher than those of countries with similar income levels. This, together with the former observation on the effect of the nationality of producers casts doubt on the ability of countries to pursue "free-riding" regulation.Pharmaceutical prices
Improving Knowledge Retrieval in Digital Libraries Applying Intelligent Techniques
Nowadays an enormous quantity of heterogeneous and distributed information is stored in the digital University. Exploring online collections to find knowledge relevant to a user’s interests is a challenging work. The artificial intelligence and Semantic Web provide a common framework that allows knowledge to
be shared and reused in an efficient way. In this work we propose a comprehensive approach for discovering E-learning objects in large digital collections based on analysis of recorded semantic metadata in those objects and the application of expert system technologies. We have used Case Based-Reasoning
methodology to develop a prototype for supporting efficient retrieval knowledge from online repositories.
We suggest a conceptual architecture for a semantic search engine. OntoUS is a collaborative effort that
proposes a new form of interaction between users and digital libraries, where the latter are adapted to users
and their surroundings
Ranking Alternatives on the Basis of the Intensity of Dominance and Fuzzy Logic within MAUT
We introduce dominance measuring methods to derive a ranking of alternatives to deal with incomplete information in multi-criteria decision making problems on the basis of Multi-Attribute Utility Theory (MAUT). We consider the situation where the alternative performances are represented by uniformly distributed intervals, and there exists imprecision concerning the decision-makersÂż preferences, by means of classes of individual utility functions and imprecise weights represented by weight intervals or fuzzy weights, respectively. An additive multi-attribute utility model is used to evaluate the alternatives under consideration, which is considered a valid approach in most practical cases. The approaches we propose are based on the dominance values between pairs of alternatives that can be computed by linear programming, which are then transformed into dominance intensities from which a dominance intensity measure is derived. The methods proposed are compared with other existing dominance measuring methods and other methodologies by Monte Carlo simulation techniques. The performance is analyzed in terms of two measures of efficacy: hit ratio, the proportion of all cases in which the method selects the same best alternative as in the TRUE ranking, and the Rank-order correlation, which represents how similar the overall rank structures of alternatives are in the TRUE ranking and in the ranking derived from the method. The approaches are illustrated with an example consisting on the selection of intervention strategies to restore an aquatic ecosystem contaminated by radionuclides
Demand methods of price management: An empirical research
One factor which companies often take as a reference point for their pricing decisions is demand. This, however, is often done only partially, with priority being given to quantitative factors rather than qualitative factors. In this context, the aim of this study was to supply companies with a tool to facilitate and enhance price management in areas related to demand.
In order to achieve this objective, the following procedure was implemented. Firstly, an extensive review of existing literature was carried out. This has made it possible to identify a set of factors which can influence consumer behaviour with respect to prices, and which should therefore be taken into account when making pricing decisions.
The factors identified were then grouped into several categories (variables related to price, variables related to the product, variables related to the characteristics and the behaviour of the consumer, and variables related to the context of the purchase), in order to offer an overall, linked view.
An empirical study was then carried out, interviewing price managers in a selection of companies from Andalusia (Spain). The objective was to gather data on their methods of price management, and to evaluate the practical usefulness of the sets of factors identified.
The results of the study have made it possible to draw some interesting conclusions on price management. One of these is the importance which companies attach to pricing decisions. These decisions were taken in all cases by higher management teams.
However, on analysing the factors which intervene in pricing decisions, it has been observed that their number is limited. In general, cost is still the major factor, while demandrelated aspects, in particular qualitative aspects, play a secondary role.
On investigating the reasons for the priority given to quantitative rather than
qualitative data, interviewees basically gave two answers. On the one hand, quantitative information (costs and sales) is easier to obtain, use and interpret than qualitative information (motivation, perception and attitude). On the other hand, most companies, and in particular the smaller ones, have no budget available for qualitative market studies.
There may be a third reason for this behaviour, which was not explicitly mentioned at first by interviewees. This is the lack of knowledge regarding qualitative demand factors: their nature, their meaning, their usefulness and the way in which they can be incorporated into pricing decisions.
This study is a first step towards solving this deficiency, since it proposes a chart which contains numerous restrictions in an integrated, organised fashion. Logically, it would be impractical to take them all into account simultaneously. This is where the work of each company begins, using market studies to establish priorities between the different factors
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