127 research outputs found
Discovery of inverse-Compton X-ray emission and estimate of the volume-averaged magnetic field in a galaxy group
Observed in a significant fraction of clusters and groups of galaxies,
diffuse radio synchrotron emission reveals the presence of relativistic
electrons and magnetic fields permeating large-scale systems of galaxies.
Although these non-thermal electrons are expected to upscatter cosmic microwave
background photons up to hard X-ray energies, such inverse-Compton (IC) X-ray
emission has so far not been unambiguously detected on cluster/group scales.
Using deep, new proprietary XMM-Newton observations (200 ks of clean
exposure), we report a 4.6 detection of extended IC X-ray emission in
MRC 0116+111, an extraordinary group of galaxies at . Assuming a
spectral slope derived from low-frequency radio data, the detection remains
robust to systematic uncertainties. Together with low-frequency radio data from
GMRT, this detection provides an estimate for the volume-averaged magnetic
field of G within the central part of the group. This
value can serve as an anchor for studies of magnetic fields in the largest
gravitationally bound systems in the Universe.Comment: 11 pages, 7 figures, accepted for publication in MNRA
Shaken Snow Globes:Kinematic Tracers of the Multiphase Condensation Cascade in Massive Galaxies, Groups, and Clusters
We propose a novel method to constrain turbulence and bulk motions in massive galaxies, galaxy groups, and clusters, exploring both simulations and observations. As emerged in the recent picture of top-down multiphase condensation, hot gaseous halos are tightly linked to all other phases in terms of cospatiality and thermodynamics. While hot halos (∼10 7 K) are perturbed by subsonic turbulence, warm (∼10 4 K) ionized and neutral filaments condense out of the turbulent eddies. The peaks condense into cold molecular clouds (<100 K) raining in the core via chaotic cold accretion (CCA). We show that all phases are tightly linked in terms of the ensemble (wide-aperture) velocity dispersion along the line of sight. The correlation arises in complementary long-term AGN feedback simulations and high-resolution CCA runs, and is corroborated by the combined Hitomi and new Integral Field Unit measurements in the Perseus cluster. The ensemble multiphase gas distributions (from the UV to the radio band) are characterized by substantial spectral line broadening (σ v,los ≈ 100-200 ) with a mild line shift. On the other hand, pencil-beam detections (as H i absorption against the AGN backlight) sample the small-scale clouds displaying smaller broadening and significant line shifts of up to several 100 (for those falling toward the AGN), with increased scatter due to the turbulence intermittency. We present new ensemble σ v,los of the warm H+[N ii] gas in 72 observed cluster/group cores: the constraints are consistent with the simulations and can be used as robust proxies for the turbulent velocities, in particular for the challenging hot plasma (otherwise requiring extremely long X-ray exposures). Finally, we show that the physically motivated criterion C ≡ t cool/t eddy ≈ 1 best traces the condensation extent region and the presence of multiphase gas in observed clusters and groups. The ensemble method can be applied to many available spectroscopic data sets and can substantially advance our understanding of multiphase halos in light of the next-generation multiwavelength missions. </p
Magnetic Field Amplification in Galaxy Clusters and its Simulation
We review the present theoretical and numerical understanding of magnetic
field amplification in cosmic large-scale structure, on length scales of galaxy
clusters and beyond. Structure formation drives compression and turbulence,
which amplify tiny magnetic seed fields to the microGauss values that are
observed in the intracluster medium. This process is intimately connected to
the properties of turbulence and the microphysics of the intra-cluster medium.
Additional roles are played by merger induced shocks that sweep through the
intra-cluster medium and motions induced by sloshing cool cores. The accurate
simulation of magnetic field amplification in clusters still poses a serious
challenge for simulations of cosmological structure formation. We review the
current literature on cosmological simulations that include magnetic fields and
outline theoretical as well as numerical challenges.Comment: 60 pages, 19 Figure
The cavity of 3CR 196.1: H emission spatially associated with an X-ray cavity
We present a multifrequency analysis of the radio galaxy 3CR 196.1 (), associated with the brightest galaxy of the cool core cluster
CIZAJ0815.4-0303. This nearby radio galaxy shows a hybrid radio morphology and
an X-ray cavity, all signatures of a turbulent past activity, potentially due
to merger events and AGN outbursts. We present results of the comparison
between and VLT/MUSE data for the inner region of the galaxy cluster,
on a scale of tens of kpc. We discovered H + [N II]
emission spatially associated with the X-ray cavity (at 10 kpc from the
galaxy nucleus) instead of with its rim. This result differs from previous
discoveries of ionized gas surrounding X-ray cavities in other radio galaxies
harbored in galaxy clusters and could represent the first reported case of
ionized gas filling an X-ray cavity, either due to different AGN outbursts or
to the cooling of warm ( K) AGN outflows. We also found that
the H, [N II] and [S
II] emission lines show an additional redward
component, at 1000 kms from rest frame, with no detection in
H or [O III]. We believe the most likely
explanation for this redward component is the presence of a background gas
cloud since there appears to be a discrete difference in velocities between
this component and the rest frame.Comment: 15 pages, 8 figures, ApJ accepted, pre-proof versio
Evidence of Runaway Gas Cooling in the Absence of Supermassive Black Hole Feedback at the Epoch of Cluster Formation
Cosmological simulations, as well as mounting evidence from observations, have shown that supermassive black holes play a fundamental role in regulating the formation of stars throughout cosmic time. This has been clearly demonstrated in the case of galaxy clusters in which powerful feedback from the central black hole is preventing the hot intracluster gas from cooling catastrophically, thus reducing the expected star formation rates by orders of magnitude. These conclusions, however, have been almost entirely based on nearby clusters. Based on new Chandra X-ray observations, we present the first observational evidence for massive, runaway cooling occurring in the absence of supermassive black hole feedback in the high-redshift galaxy cluster SpARCS104922.6 + 564032.5 (z = 1.709). The hot intracluster gas appears to be fueling a massive burst of star formation (≈900 M⊙ yr⁻¹) that is offset by dozens of kpc from the central galaxy. The burst is co-spatial with the coolest intracluster gas but not associated with any galaxy in the cluster. In less than 100 million years, such runaway cooling can form the same amount of stars as in the Milky Way. Therefore, intracluster stars are not only produced by tidal stripping and the disruption of cluster galaxies, but can also be produced by runaway cooling of hot intracluster gas at early times. Overall, these observations show the dramatic impact when supermassive black hole feedback fails to operate in clusters. They indicate that in the highest overdensities, such as clusters and protoclusters, runaway cooling may be a new and important mechanism for fueling massive bursts of star formation in the early universe
Fine mapping of qSTV11KAS, a major QTL for rice stripe disease resistance
Rice stripe disease, caused by rice stripe virus (RSV), is one of the most serious diseases in temperate rice-growing areas. In the present study, we performed quantitative trait locus (QTL) analysis for RSV resistance using 98 backcross inbred lines derived from the cross between the highly resistant variety, Kasalath, and the highly susceptible variety, Nipponbare. Under artificial inoculation in the greenhouse, two QTLs for RSV resistance, designated qSTV7 and qSTV11KAS, were detected on chromosomes 7 and 11 respectively, whereas only one QTL was detected in the same location of chromosome 11 under natural inoculation in the field. The stability of qSTV11KAS was validated using 39 established chromosome segment substitution lines. Fine mapping of qSTV11KAS was carried out using 372 BC3F2:3 recombinants and 399 BC3F3:4 lines selected from 7,018 BC3F2 plants of the cross SL-234/Koshihikari. The qSTV11KAS was localized to a 39.2 kb region containing seven annotated genes. The most likely candidate gene, LOC_Os11g30910, is predicted to encode a sulfotransferase domain-containing protein. The predicted protein encoded by the Kasalath allele differs from Nipponbare by a single amino acid substitution and the deletion of two amino acids within the sulfotransferase domain. Marker-resistance association analysis revealed that the markers L104-155 bp and R48-194 bp were highly correlated with RSV resistance in the 148 landrace varieties. These results provide a basis for the cloning of qSTV11KAS, and the markers may be used for molecular breeding of RSV resistant rice varieties
Sphingomimetic multiple sclerosis drug FTY720 activates vesicular synaptobrevin and augments neuroendocrine secretion
Neurotransmission and secretion of hormones involve a sequence of protein/lipid interactions with lipid turnover impacting on vesicle trafficking and ultimately fusion of secretory vesicles with the plasma membrane. We previously demonstrated that sphingosine, a sphingolipid metabolite, promotes formation of the SNARE complex required for membrane fusion and also increases the rate of exocytosis in isolated nerve terminals, neuromuscular junctions, neuroendocrine cells and in hippocampal neurons. Recently a fungi-derived sphingosine homologue, FTY720, has been approved for treatment of multiple sclerosis. In its non-phosphorylated form FTY720 accumulates in the central nervous system, reaching high levels which could affect neuronal function. Considering close structural similarity of sphingosine and FTY720 we investigated whether FTY720 has an effect on regulated exocytosis. Our data demonstrate that FTY720 can activate vesicular synaptobrevin for SNARE complex formation and enhance exocytosis in neuroendocrine cells and neurons
Lethal Influenza Virus Infection in Macaques Is Associated with Early Dysregulation of Inflammatory Related Genes
The enormous toll on human life during the 1918–1919 Spanish influenza pandemic is a constant reminder of the potential lethality of influenza viruses. With the declaration by the World Health Organization of a new H1N1 influenza virus pandemic, and with continued human cases of highly pathogenic H5N1 avian influenza virus infection, a better understanding of the host response to highly pathogenic influenza viruses is essential. To this end, we compared pathology and global gene expression profiles in bronchial tissue from macaques infected with either the reconstructed 1918 pandemic virus or the highly pathogenic avian H5N1 virus A/Vietnam/1203/04. Severe pathology was observed in respiratory tissues from 1918 virus-infected animals as early as 12 hours after infection, and pathology steadily increased at later time points. Although tissues from animals infected with A/Vietnam/1203/04 also showed clear signs of pathology early on, less pathology was observed at later time points, and there was evidence of tissue repair. Global transcriptional profiles revealed that specific groups of genes associated with inflammation and cell death were up-regulated in bronchial tissues from animals infected with the 1918 virus but down-regulated in animals infected with A/Vietnam/1203/04. Importantly, the 1918 virus up-regulated key components of the inflammasome, NLRP3 and IL-1β, whereas these genes were down-regulated by A/Vietnam/1203/04 early after infection. TUNEL assays revealed that both viruses elicited an apoptotic response in lungs and bronchi, although the response occurred earlier during 1918 virus infection. Our findings suggest that the severity of disease in 1918 virus-infected macaques is a consequence of the early up-regulation of cell death and inflammatory related genes, in which additive or synergistic effects likely dictate the severity of tissue damage
An experimental study of low-level laser therapy in rat Achilles tendon injury
The aim of this controlled animal study was to investigate the effect of low-level laser therapy (LLLT) administered 30 min after injury to the Achilles tendon. The study animals comprised 16 Sprague Dawley male rats divided in two groups. The right Achilles tendons were injured by blunt trauma using a mini guillotine, and were treated with LLLT or placebo LLLT 30 min later. The injury and LLLT procedures were then repeated 15 hours later on the same tendon. One group received active LLLT (λ = 904 nm, 60 mW mean output power, 0.158 W/cm2 for 50 s, energy 3 J) and the other group received placebo LLLT 23 hours after LLLT. Ultrasonographic images were taken to measure the thickness of the right and left Achilles tendons. Animals were then killed, and all Achilles tendons were tested for ultimate tensile strength (UTS). All analyses were performed by blinded observers. There was a significant increase in tendon thickness in the active LLLT group when compared with the placebo group (p < 0.05) and there were no significant differences between the placebo and uninjured left tendons. There were no significant differences in UTS between laser-treated, placebo-treated and uninjured tendons. Laser irradiation of the Achilles tendon at 0.158 W/cm2 for 50 s (3 J) administered within the first 30 min after blunt trauma, and repeated after 15 h, appears to lead to edema of the tendon measured 23 hours after LLLT. The guillotine blunt trauma model seems suitable for inflicting tendon injury and measuring the effects of treatment on edema by ultrasonography and UTS. More studies are needed to further refine this model
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