Physiological responses in a simulated canarian wrestling contest

La Lucha Canaria (LC) ha sido recientemente reconocida como deporte por el Consejo Superior de Deportes, aunque su origen se pierde en el tiempo. Sin embargo, no hay ningún trabajo en la bibliografía científica que describa qué ocurre fisiológicamente durante la competición en esta modalidad de lucha, y éste es el objetivo del presente trabajo. Con una muestra de 12 luchadores de alto nivel (puntales) simulamos el sistema de competición actual en Lucha Canaria. Se estudió la frecuencia cardiaca, la tensión arterial y la concentración de lactato en sangre en diferentes momentos de la simulación. Los patrones observados de respuesta de FC, TA y lactato, caracterizan a la competición en LC como un ejercicio intermitente, con picos de intensidad que superan el umbral láctico y determinan incrementos importantes de FC y TA sistólica. Este estudio es el primero en que se valora la respuesta fisiológica del luchador canario en competición.The aim of this article is to describe what happens from a physiological point of view in a Canarian Wrestling (CW) contest. The Spanish National Sports Council recognized Canarian Wrestling as a sport on June 1st, 2009, although its origin is not very well documented. No scientific article exists in the scientific literature to describe what happens physiologically during a CW contest. Twelve high level wrestlers were recruited to simulate a CW match. The study involved data about heart rate (HR), blood pressure (BP) and blood lactate levels (L) at different moments of the combat. The conclusions of the data observed concerning HR, BP and L classify Canarian Wrestling as an intermittent exercise, with intensity peaks that exceed the lactic threshold and high levels of HR and systolic BP. This is the first paper in which the physiological responses in a Canarian Wrestling competition are reported

Life history of an anticyclonic eddy

19 pages, 11 figures, 1 table, supporting information https://doi.org/10.1029/2004JC002526We use the trajectory of three buoys dragged below the surface mixed layer, together with sea surface temperature imagery, to examine the evolution of an anticyclonic warm-core eddy since its generation by the Canary Islands. Two buoys remain within the eddy during some 100 days, and the third one remains almost 200 days, while drifting southwestward up to 500 km with the mean Canary Current. The eddy merges with several younger anticyclonic and cyclonic eddies, in each occasion, suffering substantial changes. The eddy core, defined as a region with near-solid-body-type rotation and radial convergence, initially occupies the whole eddy. After interacting with another vortex the inner core markedly slows down, although it continues displaying radial convergence and relatively small radial oscillations, and an uncoupled outer ring is formed or enhanced, which revolves even more slowly and displays large radial fluctuations. The vortex extensive life is consistent with its inertially stable character and observations of radial convergence. A very simple model of vortex merging, where cylinders fuse conserving mass and angular momentum, gives fair results. The observations suggest that the eddy changes, as the result of its own slow evolution and sporadic mixing events, from a young stage, where the core retains its vorticity and occupies most of the eddy, through a mature stage, where the eddy has a reduced inner core and a slowly revolving outer ring, to a decay stage, where the vorticity maximum is substantially reducedThis work has been supported by the Spanish government through projects FRENTES (AMB95-0731), COCA (REN2000-1471-C02-02MAR), and BREDDIES (REN2001-2650/ANT) and the special action MAR1999-1489-E and by the European Union through projects CANIGO (MAS3-CT96-0060) and OASIS (EVK3-CT-2002-00073-OASIS)Peer Reviewe

¿Qué esperan encontrar los alumnos en los estudios de Psicología? Metas y motivos personales de los estudiantes en su primer año en la universidad

Numerosas investigaciones se han interesado por el perfil motivacional de ingreso de los universitarios. Sin embargo, se ha prestado menos atención al estudio de las metas que los estudiantes pretenden satisfacer cuando llegan a la universidad. En este trabajo presentamos un primer estudio con 610 alumnos de Psicología, de cuatro cursos consecutivos. En él se analiza la estructura factorial de una escala que evalúa la identificación de los estudiantes con diferentes tipos de motivos. En un segundo estudio, con otros 140 estudiantes, se relacionan las metas interpersonales con otras metas vitales, la satisfacción de necesidades psicológicas, el bienestar subjetivo y la presencia de pensamientos perfeccionistas. Los datos muestran la importancia de las metas de logro, de poder, de afiliación y de superación de problemas personales. Estas últimas presentan, además, una relación negativa con el bienestar y la satisfacción de necesidades psicológicas, y una relación positiva con el perfeccionismo. Nuestros resultados aportan un mayor conocimiento de los perfiles de los estudiantes de nuevo ingreso y las consecuencias que de ellos se derivan para su orientación académica

Modelling PM2.5 chemical composition with CAMx in southwest Spain

Comunicación presentada en: 2012 European Aerosol Conference (EAC-2012), B-WG01S2P30, celebrada del 2 al 7 de septiembre de 2012 en Granada

Measurements and simulation of speciated PM2.5 in south-west Europe

Chemically speciated concentrations of PM2.5 (sulphate, ammonium, nitrate, elemental and organic carbon) were simulated in south-west Europe using the three-dimensional air quality model CAMx driven by the MM5 meteorological model. The inner domain covered the south-west region of Spain with a high spatial (2 km × 2 km) and temporal resolution (1 h). The simulation results were evaluated against experimental data obtained in four intensive field campaigns performed in 2008 and 2009 at urban and rural sites. PM2.5 measurements of secondary inorganic compounds and carbonaceous aerosol plus a suite of major and trace elements were determined. High time resolution (10 min) measurements of Black Carbon (BC) were also conducted. The model captured the variability in the ammonium concentrations in both summer and winter periods, although it tended to underestimate the magnitude of concentrations, while for sulphate the performance was better during the summer periods. Particulate ammonium nitrate was only simulated in significant concentrations in the wintertime campaign. This was found to be consistent with the measured composition of PM2.5 where most of nitrate (79–94%) and a significant fraction of sulphate (24–37%) were estimated to be present as non-ammonium salts. These non-ammonium nitrate salts were attributed to the formation of NaNO3. The model PM2.5 primary elemental carbon simulations, evaluated with hourly resolution, captured the diurnal and seasonal variability of PM2.5 BC concentrations at the urban site while poorer performance was observed at the rural site. A large underestimation was observed for simulated PM2.5 organic carbon concentrations during all campaigns. Scenarios of pollution events linked to emissions from south-west Spain, shipping and contributions from more distant emission sources such as Portugal were identified. These results highlight how the distinct features of PM2.5 composition in southern Europe regions, such as the large contribution of non-ammonium salts, need to be taken into account both in model evaluation and in future implementation of aerosol modelling systems.The authors gratefully acknowledge funding from the Department of Innovation, Science and Enterprise of the Government of Andalusia through the research projects AER-REG (P07-RNM- 03125) and SIMAND (P07-RNM-02729) and from the Department of Environment, Andalusian Regional Government (project: 199/ 2011/C/00). In addition, we thank the Spanish Ministry of Economy and Competitiveness for funding through the project POLLINDUST (CGL2011-26259)

Biogeochemistry of dissolved and suspended organic matter in the Cape Vert Frontal Zone (NW Africa)

Oral communicationThe Cape Verde Frontal Zone (CVFZ) in the southern boundary of the Canary Current Upwelling Ecosystem, is a highly dynamic area, featuring large vertical and horizontal export fluxes of organic matter (OM) due to the interaction of the Cape Verde Front (CVF) with the Mauritanian upwelling. To study the interplay between transport and biogeochemical processes driving the distribution of OM in the CVFZ, full-depth profiles of dissolved (DOM) and suspended particulate (POM) OM were obtained during the FLUXES I cruise in August 2017. Distributions of surface DOM and POM and their stoichiometry were influenced by the mesoscale variability at the frontal region, showing significant differences north and south of the CVF and between stations close and distant to the Mauritanian coast. The C:N molar ratio of DOM and POM showed average vertical gradients, increasing from 12.1 and 8.0 in surface to 15.6 and 17.0 respectively in deeps waters, deviating from the traditional Redfield ratio. In the meso- and bathypelagic zones, meridional and cross-shore gradients were detected within samples belonging to the same water mass, indicating that their properties were re-shaped by biogeochemical processes within the CVFZ. Correlations between apparent oxygen utilization and OM indicate that DOM+POM contributed only to 8.1% of the carbon and 17.8% of the nitrogen mineralisation in the water column, suggesting that the local carbon demand is mainly supported by sinking POM and N containing compounds are mineralised to a larger extend than C containing compoundsASL

Design and baseline characteristics of SALT-HF trial: hypertonic saline therapy in ambulatory heart failure

Aims: Hypertonic saline solution (HSS) plus intravenous (IV) loop diuretic appears to enhance the diuretic response in patients hospitalized for heart failure (HF). The efficacy and safety of this therapy in the ambulatory setting have not been evaluated. We aimed to describe the design and baseline characteristics of the SALT-HF trial participants. Methods and results: ‘Efficacy of Saline Hypertonic Therapy in Ambulatory Patients with HF’ (SALT-HF) trial was a multicenter, double-blinded, and randomized study involving ambulatory patients who experienced worsening heart failure (WHF) without criteria for hospitalization. Enrolled patients had to present at least two signs of volume overload, use ≥ 80 mg of oral furosemide daily, and have elevated natriuretic peptides. Patients were randomized 1:1 to treatment with a 1-h infusion of IV furosemide plus HSS (2.6–3.4% NaCl depending on plasmatic sodium levels) versus a 1-h infusion of IV furosemide at the same dose (125–250 mg, depending on basal loop diuretic dose). Clinical, laboratory, and imaging parameters were collected at baseline and after 7 days, and a telephone visit was planned after 30 days. The primary endpoint was 3-h diuresis after treatment started. Secondary endpoints included (a) 7-day changes in congestion data, (b) 7-day changes in kidney function and electrolytes, (c) 30-day clinical events (need of IV diuretic, HF hospitalization, cardiovascular mortality, all-cause mortality or HF-hospitalization). Results: A total of 167 participants [median age, 81 years; interquartile range (IQR), 73–87, 30.5% females] were randomized across 13 sites between December 2020 and March 2023. Half of the participants (n = 82) had an ejection fraction >50%. Most patients showed a high burden of comorbidities, with a median Charlson index of 3 (IQR: 2–4). Common co-morbidities included diabetes mellitus (41%, n = 69), atrial fibrillation (80%, n = 134), and chronic kidney disease (64%, n = 107). Patients exhibited a poor functional NYHA class (69% presenting NYHA III) and several signs of congestion. The mean composite congestion score was 4.3 (standard deviation: 1.7). Ninety per cent of the patients (n = 151) presented oedema and jugular engorgement, and 71% (n = 118) showed lung B lines assessed by ultrasound. Median inferior vena cava diameter was 23 mm, (IQR: 21–25), and plasmatic levels of N-terminal-pro-B-type natriuretic peptide (NTproBNP) and antigen carbohydrate 125 (CA125) were increased (median NT-proBNP 4969 pg/mL, IQR: 2508–9328; median CA125 46 U/L, IQR: 20–114). Conclusions: SALT-HF trial randomized 167 ambulatory patients with WHF and will determine whether an infusion of hypertonic saline therapy plus furosemide increases diuresis and improves decongestion compared to equivalent furosemide administration alone

Chloro-Furanocembranolides from Leptogorgia sp. Improve Pancreatic Beta-Cell Proliferation

Type 2 diabetes (T2DM) is a complex disease linked to pancreatic beta-cell failure and insulin resistance. Current antidiabetic treatment regimens for T2DM include insulin sensitizers and insulin secretagogues. We have previously demonstrated that leptolide, a member of the furanocembranolides family, promotes pancreatic beta-cell proliferation in mice. Considering the beneficial effects of leptolide in diabetic mice, in this study, we aimed to address the capability of leptolide to improve insulin resistance associated with the pathology of obesity. To this end, we tested the hypothesis that leptolide should protect against fatty acid-induced insulin resistance in hepatocytes. In a time-dependent manner, leptolide (0.1 µM) augmented insulin-stimulated phosphorylation of protein kinase B (PKB) by two-fold above vehicle-treated HepG2 cells. In addition, leptolide (0.1 µM) counteracted palmitate-induced insulin resistance by augmenting by four-fold insulin-stimulated phosphorylation of PKB in HepG2 cells. In vivo, acute intraperitoneal administration of leptolide (0.1 mg/kg and 1 mg/kg) improved glucose tolerance and insulin sensitivity in lean mice. Likewise, prolonged leptolide treatment (0.1 mg/kg) in diet-induced obese mice improved insulin sensitivity. These effects were paralleled with an ~50% increased of insulin-stimulated phosphorylation of PKB in liver and skeletal muscle and reduced circulating pro-inflammatory cytokines in obese mice. We concluded that leptolide significantly improves insulin sensitivity in vitro and in obese mice, suggesting that leptolide may be another potential treatment for T2DMMinisterio de Ciencia e Innovación (SAF2009-0839 and RTA 2015-00010-C03-02). ARDM acknowledges funding from IMBRAIN project (FP7-REGPOT-2012-CT2012-31637-IMBRAIN) and from Cabildo de Tenerife (Agustín de Betancourt Programme). A.B.G. would like to thank Convenio Universidad de Magallanes (Chile) and CSIC, project 2009CL0031, for financial support

XI CIDU. La transformación digital de la universidad Congreso Iberoamericano de Docencia Universitaria

Nesta comunicação apresenta-se uma experiência de gamificação realizada numa turma online, numa Universidade Virtual. Foram utilizados como elementos de jogo pontos, badges, leadboard, avatares e desafios. Do ponto de vista do desenho da unidade curricular, foi proposto um desafio global, sob a forma de roleplaying, que percorreu todo o semestre. Para este desafio global contribuíram três outros desafios, nos quais os estudantes deveriam dinamizar discussões, sendo atribuídos pontos e badges em função da sua prestação. No que se refere à metodologia, tratou-se de uma investigação exploratória, com carácter qualitativo. Como técnicas de recolha de dados, privilegiou-se a observação, realizada durante toda a unidade curricular, complementada por um questionário aos estudantes no final do semestre. Constatou-se que a estratégia adotada incentivou a participação ativa dos estudantes, tendo estes gostado da experiência. Verificaram-se, contudo, algumas limitações, pelo facto de os estudantes desta amostra serem adultos trabalhadores a frequentar uma licenciatura online, com outros compromissos profissionais e familiares. Com efeito, verificou-se que vários deles mencionaram ter dificuldade na gestão do tempo, limitando a possibilidade de adesão a um percurso exigente em termos de participação ativa.In this paper, we present a gamification experiment that took place in an online class at a virtual university. The game elements were points, badges, leaderboard, avatars and challenges. Taking into account the curricular unit design, a global challenge was proposed, in the form of roleplaying, and took place along the whole semester. Three other challenges contributed to this global challenge: the students had to dynamize debates, and received points and badges, according to their performance. In terms of methodology, it consisted in an exploratory research of a qualitative character. Observation, complemented by a questionnaire made available to the students at the end of the semester, were the chosen techniques for data collection. It was observed that the adopted strategy motivated the students’ active participation, who really enjoyed the experience. However, some limitations were also observed, once these students, attending an online First Cycle Degree, are adults who have professional and family responsibilities and commitments. Actually, several of them mentioned that the difficulty in organizing their time did limit the possibility of participating in the challenge, which was indeed demanding in terms of active participation.info:eu-repo/semantics/publishedVersio