519 research outputs found
How to promote interdisciplinary R&D in the academia: the case of the “House of the Future”
While empirical research does indeed suggest that collaborative R&D has many desirable outcomes,
it is also clear that collaborative work is difficult and expensive. The challenge becomes increasingly
sharp as complex and expensive research questions require a large pool of resources and a
combination of specialized disciplines. As a result, different organizations get involved in
interdisciplinary projects to expand the frontiers of knowledge. This paper analyzes the strategy
and methodological approaches used to mobilize interdisciplinary R&D within a universityindustry
network named ‘House of the Future’. We discuss the implications of our research for
R&D networks design
Innovation cooperation networks: case of a multisectoral and interdisciplinary partnership
Network cooperation processes gained special interest in the new knowledge economy as
they provide better conditions to innovation and knowledge creation and diffusion.
Although the importance of this strategic tool has been increasingly recognized,
individualistic behaviour tends to prevail within small and medium-sized firms and many of
them continue to exhibit an attitude of resistance when dealing with collaborative
experiences.
This paper has two main goals. First, it explores how networks can promote innovation
and help overcome the difficulties inherent in cooperation processes. Second, it illustrates
an innovative approach to network cooperation in a multisectoral and inter-disciplinary
environment, presenting the experience of the “House of the Future” network in Aveiro,
Portugal
Caractéristiques et classification des principaux sols du Val Jaguaribe (Etat du Ceara, Brésil)
Corpo, maturação biológica e actividade física: um olhar interactivo em crianças e jovens madeirenses
Cada vez mais a sociedade moderna é olhada através da sua condição
física, enquanto factor de bem-estar, saúde, qualidade de vida e longevidade
dos seus membros.
Os indicadores demográficos actuais da população madeirense
apontam no sentido de uma considerável componente juvenil, adolescente e
jovem. No entanto, a evolução demográfica prevista, decorrente de um
acentuado decréscimo da natalidade, leva a prever um comportamento diverso
da pirâmide de idades, assumindo particular ênfase as questões relacionadas
com o estudo e a investigação do corpo, a procura de padrões, a descrição
normativa, a interpretação das mudanças e o espaço morfológico externo, que
se vem enquadrar no território de investigação reservado à somatotipologia
Octonion Quantum Chromodynamics
Starting with the usual definitions of octonions, an attempt has been made to
establish the relations between octonion basis elements and Gell-Mann \lambda
matrices of SU(3)symmetry on comparing the multiplication tables for Gell-Mann
\lambda matrices of SU(3)symmetry and octonion basis elements. Consequently,
the quantum chromo dynamics (QCD) has been reformulated and it is shown that
the theory of strong interactions could be explained better in terms of
non-associative octonion algebra. Further, the octonion automorphism group
SU(3) has been suitably handled with split basis of octonion algebra showing
that the SU(3)_{C}gauge theory of colored quarks carries two real gauge fields
which are responsible for the existence of two gauge potentials respectively
associated with electric charge and magnetic monopole and supports well the
idea that the colored quarks are dyons
Dual imaging gold nanoplatforms for targeted radiotheranostics
Gold nanoparticles (AuNPs) are interesting for the design of new cancer theranostic tools, mainly due to their biocompatibility, easy molecular vectorization, and good biological half-life. Herein, we report a gold nanoparticle platform as a bimodal imaging probe, capable of coordinating Gd3+ for Magnetic Resonance Imaging (MRI) and 67Ga3+ for Single Photon Emission Computed Tomography (SPECT) imaging. Our AuNPs carry a bombesin analogue with anity towards the gastrin releasing peptide receptor (GRPr), overexpressed in a variety of human cancer cells, namely PC3 prostate cancer cells. The potential of these multimodal imaging nanoconstructs was thoroughly investigated by the assessment of their magnetic properties, in vitro cellular uptake, biodistribution, and radiosensitisation assays. The relaxometric properties predict a potential T1-and T2-MRI application. The promising in vitro cellular uptake of 67Ga/Gd-based bombesin containing particles was confirmed through biodistribution studies in tumor bearing mice, indicating their integrity and ability to target the GRPr. Radiosensitization studies revealed the therapeutic potential of the nanoparticles. Moreover, the DOTA chelating unit moiety versatility gives a high theranostic potential through the coordination of other therapeutically interesting radiometals. Altogether, our nanoparticles are interesting nanomaterial for theranostic application and as bimodal T1-and T2-MRI / SPECT imaging probes.This research was funded by FCT (Portuguese Foundation for Science and Technology), grant
numbers EXCL/QEQ-MED/0233/2012, UID/Multi/04349/2013 and PTDC/MED-QUI/29649/2017. CFGCG and
MMCAC thank FCT and FEDER through the COMPETE Program for funding the CQC (UID/QUI/00313/2013 and
PEst-OE/QUI/UI0313/2014). P.L-L. thanks Ministry of Economy, Industry and Competitiviy for SAF2017-83043-R,
and Comunity of Madrid, FEDER and FSE for S2017/BMD-368
Influência de extratos de formas evolutivas sobre atividades de oviposição de fêmeas de Aedes (s) albopictus (Skuse)
Surtos de enfermidades transmitidas por alimentos causados por Salmonella Enteritidis
OBJETIVO: São descritos surtos de salmonelose notificados no período de julho de 1993 a junho de 1997 na região Noroeste do Estado de São Paulo, Brasil, tendo em vista os vários surtos de veiculação alimentar ocasionados por Salmonella nessa região. MÉTODO: Foram obtidos 19 inquéritos epidemiológicos para análise de dados, 87 amostras de fezes e 38 amostras de alimentos, incluindo 12 de ovos para análise microbiológica. Cepas de Salmonella foram submetidas a sorotipagem, fagotipagem e teste de sensibilidade a 13 agentes antimicrobianos. RESULTADOS: Foram acometidas 906 pessoas com 295 hospitalizações. Cepas de Salmonella Enteritidis Fagotipo 4 foram isoladas de 80,5% das coproculturas, de todas amostras de alimentose de 41,7% dos ovos. Em 22 (95,7%) surtos os a salmonela foi veiculada por alimentos contendo ovos crus ou semicrus. Os testes de sensibilidade a antimicrobianos revelaram sensibilidade à maioria das cepas. CONCLUSÕES: Considerando os resultados obtidos, torna-se necessária a implantação e intensificação de medidas de controle na produção e armazenamento dos ovos, além da orientação à população quanto aos riscos no consumo inadequado desse alimento.OBJECTIVE: It is to describe outbreaks of salmonellosis reported from July 1993 through June 1997 in the Northwest region of S. Paulo State, Brazil, one of the areas where several foodborne outbreaks of salmonellosis have been recently detected. METHOD: Data of 19 epidemiological investigations were analysed; 87 stool specimens and 38 food samples (including 12 of shell eggs) were processed for microbiological analysis. Salmonella strains were identified by serotyping, phagetyping and antimicrobial susceptibility testing. RESULTS: There were 906 ill persons including 295 hospitalized patients. Phage type 4 (PT 4) Salmonella Enteritidis strains were isolated from 80.5% of stool samples, from all food samples and from 41.7% of eggs. Of the outbreaks, 95.7% were associated with the consumption of food containing raw or undercooked eggs. All strains were susceptible to the 13 antimicrobials, except the strains from the nosocomial outbreak. CONCLUSIONS: The results obtained show the need for the implementation of control measures regarding egg procdution and storage, as well as for guidance to the public as to the risks involved in the consumption of inadequately prepared eggs
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