Universalism and Utilitarianism: An Evaluation of Two Popular Moral Theories in Business Decision Making

Moral theories remain a topic of interest, not just to moral philosophers, but increasingly in business circles as well, thanks to a tainted reputation that urges more awareness in this regard. Based on the expressed preferences of 163 undergraduate and graduate students of business ethics, this article briefly examines the two most popular theories, Universalism (Kantian) and Utilitarianism (consequentialist), and presents a SWOT analysis of both. Some of the strengths and weaknesses that will be discussed for Universalism are consistency, intension basis, and universalizability, while some of the discussed strengths and weaknesses for Utilitarianism are flexibility, outcome-basis, and lack of consistency. Subsequently, some common factors and discrepancies between the two theories will be discussed. In the conclusive section, some suggestions and recommendations are presented

A Mindful Moral Compass for Twenty-First Century Leadership: The Noble Eightfold Path

Marques reviews contemporary leaders in business, human rights advocacy, and social entrepreneur circles as examples of individuals who have channeled their efforts to guide their careers in a sustainable and morally responsible manner within the context of the ancient “Noble Eightfold Path,”— a core Buddhist philosophy. Applied to a secular world, Marques further identifies, explains, and applies the eight elements of the Path as a model for modern-day leadership

Compassionate Creativity: The Progressive Renaissance of a Seasoned Concept

In this article, I present the findings of a study conducted with 115 MBA students, who also were members of the workforce, about the qualities they would prefer to see in their managers and leaders. I first address the concerns of contemporary times by drawing an analogy between the main problems in business performance and those in business education, namely, a top-down approach, immoral practices, and stakeholder dissatisfaction. Based upon the results of the study, I then present the 10 Cs for leaders and managers, discuss their interdependency, draw a linkage with the foundational studies regarding relationship and task behaviors of leaders, and suggest a new perspective to include these behaviors in contemporary work settings

Cultivating Empathy: New Perspectives on Educating Business Leaders

Beyond rules, procedures, and manuals lie relationships. Jettisoning a formal hierarchical company structure allows all levels of management and employees to positively interact – this is where the key driver of “empathy” is so critical to continue building these relationships and molding a common organizational purpose

Towards a generic platform for developing CSCL applications using Grid infrastructure

The goal of this paper is to explore the possibility of using CSCL component-based software under a Grid infrastructure. The merge of these technologies represents an attractive, but probably quite laborious enterprise if we consider not only the benefits but also the barriers that we have to overcome. This work presents an attempt toward this direction by developing a generic platform of CSCL components and discussing the advantages that we could obtain if we adapted it to the Grid. We then propose a means that could make this adjustment possible due to the high degree of genericity that our library component is endowed with by being based on the generic programming paradigm. Finally, an application of our library is proposed both for validating the adequacy of the platform which it is based on and for indicating the possibilities gained by using it under the Grid.Peer ReviewedPostprint (published version

The Application of Interrater Reliability as a Solidification Instrument in a Phenomenological Study

Interrater reliability has thus far not been a common application in phenomenological studies. However, once the suggestion w a s brought up by a team of supervising professors during the preliminary orals of a phenomenological study, the utilization of this verification tool turned out to be vital to the credibility level of this type of inquiry, where the researcher is perceived as the main instrument and where bias may, hence, be difficult to eliminate. With creativeness and the appropriate calculation approach the researcher of the here reviewed qualitative study managed to apply this verification tool and found that the establishment of interrater reliability served as a great solidification to the research findings

LaCOLLA: A Middleware to Support Self-sufficient Collaborative Groups

In a decentralised and distributed environment, collaboration requiring the sharing and building of applications is a complex task. For this reason, we propose LaCOLLA, a fully decentralised peer-to-peer middleware that aims to simplify the process of incorporating collaborative functionalities into any application. It provides applications with certain essential collaborative functionalities: dissemination of information, storage, presence and transparency of location, management of members and groups, and execution of tasks. A distinguishing feature of LaCOLLA is that participants provide resources for the benefit of the group. This enables collaboration activities to take place in a collective environment using only the resources provided by participants in the collaboration (self-sufficiency). In this paper we present and evaluate the architecture of LaCOLLA, its API, and key aspects of its implementation

Revisiting the usefulness of the short acute octreotide test to predict treatment outcomes in acromegaly

Acromegaly; Acute octreotide test; PredictionAcromegalia; Test agudo de octreotida; PredicciónAcromegàlia; Test agut d'octreòtid; PrediccióIntroduction: We previously described that a short version of the acute octreotide test (sAOT) can predict the response to first-generation somatostatin receptor ligands (SRLs) in patients with acromegaly. We have prospectively reassessed the sAOT in patients from the ACROFAST study using current ultra-sensitive GH assays. We also studied the correlation of sAOT with tumor expression of E-cadherin and somatostatin receptor 2 (SSTR2) . Methods: A total of 47 patients treated with SRLs for 6 months were evaluated with the sAOT at diagnosis and correlated with SRLs’ response. Those patients whose IGF1 decreased to <3SDS from normal value were considered responders and those whose IGF1 was ≥3SDS, were considered non-responders. The 2 hours GH value (GH2h) after s.c. administration of 100 mcg of octreotide was used to define predictive cutoffs. E-cadherin and SSTR2 immunostaining in somatotropinoma tissue were investigated in 24/47 and 18/47 patients, respectively. Results: In all, 30 patients were responders and 17 were non-responders. GH2h was 0.68 (0.25-1.98) ng/mL in responders vs 2.35 (1.59-9.37) ng/mL in non-responders (p<0.001). GH2h = 1.4ng/mL showed the highest ability to identify responders (accuracy of 81%, sensitivity of 73.3%, and specificity of 94.1%). GH2h = 4.3ng/mL was the best cutoff for non-response prediction (accuracy of 74%, sensitivity of 35.3%, and specificity of 96.7%). Patients with E-cadherin-positive tumors showed a lower GH2h than those with E-cadherin-negative tumors [0.9 (0.3-2.1) vs 3.3 (1.5-12.1) ng/mL; p<0.01], and patients with positive E-cadherin presented a higher score of SSTR2 (7.5 ± 4.2 vs 3.3 ± 2.1; p=0.01). Conclusion: The sAOT is a good predictor tool for assessing response to SRLs and correlates with tumor E-cadherin and SSTR2 expression. Thus, it can be useful in clinical practice for therapeutic decision-making in patients with acromegaly.The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This research was funded by the Instituto de Salud Carlos III (PMP15/00027, co-funded by the European Union-ERDF; and PMP22/00021, funded by the European Union -NextGenerationEU); and Novartis through the REMAH (Registro Español Molecular de Adenomas Hipofisarios) consortium of the SEEN (Sociedad Española de Endocrinología y Nutrición). Novartis was not involved in the study design, analysis, interpretation of data, the writing of this article, or the decision to submit it for publication

Introducing MR‐TADF emitters into Light‐Emitting Electrochemical Cells for narrowband and efficient emission

The Umeå University authors wish to acknowledge generous financial support from the Swedish Research Council, the Swedish Energy Agency, Bertil och Britt Svenssons stiftelse för belysningsteknik, Länsstyrelsen Västerbotten, Kempestiftelserna, Olle Engkvists Stiftelse, Wenner-Gren Foundations, and the Wallenberg Initiative Materials Science for Sustainability, WISE. The St Andrews authors thank the Engineering and Physical Sciences Research Council (EP/R035164/1).Organic semiconductors that emit by the process of multi‐resonance thermally activated delayed fluorescence (MR‐TADF) can deliver narrowband and efficient electroluminescence while being processable from solvents and metal‐free. This renders them attractive for use as the emitter in sustainable light‐emitting electrochemical cells (LECs), but so far reports of narrowband and efficient MR‐TADF emission from LEC devices are absent. Here, this issue is addressed through careful and systematic material selection and device development. Specifically, the authors show that the detrimental aggregation tendency of an archetypal rigid and planar carbazole‐based MR‐TADF emitter can be inhibited by its dispersion into a compatible carbazole‐based blend host and an ionic‐liquid electrolyte, and it is further demonstrated that the tuning of this active material results in a desired balanced p‐ and n‐type electrochemical doping, a high solid‐state photoluminescence quantum yield of 91%, and singlet and triplet trapping on the MR‐TADF guest emitter. The introduction of this designed metal‐free active MR‐TADF material into a LEC, employing air‐stabile electrodes, results in bright blue electroluminescence of 500 cd m−2, which is delivered at a high external quantum efficiency of 3.8% and shows a narrow emission profile with a full‐width‐at‐half‐maximum of 31 nm.Publisher PDFPeer reviewe

Detection, quantification and genetic variability of Mycoplasma hyopneumoniae from apparently healthy and pneumonic swine

Mycoplasma hyopneumoniae is the causative agent of the Porcine Enzootic Pneumonia. However, this mycoplasma can be detected in healthy and symptomatic pigs, that difficults the conclusion for the etiology of this disease. In the present study we aimed to detect, quantify and do molecular analyses of M. hyopneumoniae strains in respiratory clinical samples recovered from healthy pigs and from those with pneumonia or other respiratory symptoms. The analytical sensitivity and specificity of PCR assays directed to Mollicutes detection and porcine mycoplasmas identification in clinical samples were evaluated. The identification of M. hyopneumoniae in the samples was performed using different molecular approaches, Multiplex PCR, Real Time PCR and Multilocus Variable-Number Tandem-Repeat amplification. Molecular characterization of the strains was achieved by determining and comparing the VNTR copy number directly in the samples. The highest number of samples positive to M. hyopneumoniae was identified by the multilocus VNTR amplification assay using labeled primers, followed by capillary electrophoresis. The highest concentration of M. hyopneumoniae was detected in pneumonic lungs (2, 3 * 108 genome copies /mL). The VNTR copy number analysis demonstrated that despite the high genetic variability of the M. hyopneumoniae strains, predominant strains in the swine farms could be identified by means of the VNTR copy number analysis of P97R1 and P146R3. (English)Molecular differences among Mycoplasma hyopneumoniae strains present in pneumonic lungs of swine have been largely studied. However, no comparative studies concerning the strains present in apparently healthy pigs have been carried out. This study aimed to detect, quantify and perform molecular analysis of M. hyopneumoniae strains in pig lungs with and without pneumonic lesions. The detection of M. hyopneumoniae was performed using multiplex PCR (YAMAGUTI, 2008), real-time PCR (STRAIT et al., 2008) and multiple VNTR amplification (VRANCKX et al., 2011). Molecular characterization of the strains was achieved by analysis of the VNTR copy number in P97R1, P146R3, H2R1 and H4. M. hyopneumoniae was detected in samples from healthy and pneumonic pigs and the amount of M. hyopneumoniae positive samples detected varied with the type of assay. The greater number of positive samples was identified by the multiple VNTR amplification combined with capillary electrophoresis. Using real-time PCR, 4.9*104 M. hyopneumoniae genome copies/mL was detected in apparently healthy lungs. A mean quantity of 3.9*106 M. hyopneumoniae genome copies/mL was detected in pneumonic lungs. The analysis of VNTR copy number demonstrated a high genetic variability of the M. hyopneumoniae strains present in apparently healthy and pneumonic lungs. Strains having 3 VNTR copy number in P97R1, were detected only in pneumonic lungs and strains having 40 and 43 VNTR copy number in P146R3 were detected only in apparently healthy lungs. Despite the genetic variability of M. hyopneumoniae, predominant strains in the swine farms could be identified.As diferenças moleculares entre as estirpes de Mycoplasma hyopneumoniae presentes em pulmões de suínos com pneumonia tem sido estudadas. Porém, estudos comparativos relativos as estirpes presentes nos suínos aparentemente saudáveis não foram levados a cabo. O objetivo do estudo foi a detecção, quantificação e analise molecular de M. hyopneumoniae nos pulmões suínos com e sem lesões pneumônicas. Para a detecção de M. hyopneumoniae usaramse o PCR Multiplo (YAMAGUTI, 2008), o PCR a Tempo Real (STRAIT et al., 2008) e a amplificação de múltiplo VNTR (VRANCKX et al., 2011). A caracterização molecular das estirpes foi realizada mediante a análise do número de copias de VNTR em P97R1, P146R3, H2R1 e H4. O M. hyopneumoniae foi detectado em amostras de suínos saudáveis e pneumônicos e a quantidade de M. hyopneumoniae nas amostras positivas variou com o tipo de ensaio. O maior número de amostras positivas foi identificado pela amplificação de múltiplas VNTR combinado com a eletroforese de capilares. Usando o PCR a Tempo Real, 4.9*104 copias de genoma/mL de M. hyopneumoniae foram detectadas em pulmões aparentemente saudáveis. Uma quantidade média de 3.9*106 copias de genoma/mL de M. hyopneumoniae foi detectada em pulmões pneumônicos. A análise do número de copias de VNTR demonstrou uma elevada variabilidade