11 research outputs found

    Information technologies in teaching humanitarian disciplines

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    The use of information technology in teaching humanitarian disciplines contributes to the formation of highly qualified, competitive specialists who can adapt to rapidly changing conditions, possessing a high level of development of critical and creative thinking, ready for professional self-development and self-improvement, for the implementation of reflection, capable of setting goals and systematically achieving them. The work actualizes the importance of information technology in the training of highly qualified competitive specialists capable of implementing professional activities at a high level. The purpose of the article is to analyze the experience of implementing information technologies in teaching humanitarian disciplines. Smart boards, multimedia installations, document cameras, electronic textbooks, electronic educational platforms and others were used as information technologies used in the teaching of the humanities. The study made it possible to reveal the influence of information technologies on the level of formation of students' competencies

    Molecular Determinants of Ethionamide Resistance in Clinical Isolates of <i>Mycobacterium tuberculosis</i>

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    Background: Ethionamide and prothionamide are now included in group C of the WHO recommended drugs for the treatment of tuberculosis resistant to rifampicin and multidrug-resistant tuberculosis. The clinical relevance of ethionamide and prothionamide has increased with the wide spread of resistant tuberculosis. Methods: We retrospectively analyzed 349 clinical isolates obtained between 2016 and 2020. The susceptibility to ethionamide was tested using both the BactecTM MGITTM 960 system and the SensititreTM MYCOTB plate. Results: The MIC of ethionamide increases with the total resistance of the isolates in a row from susceptible to XDR strains. A significant part of the isolates have a MIC below the breakpoint: 25%, 36%, and 50% for XDR, pre-XDR, and MDR strains. Sensitivity and specificity of detection of mutations were 96% and 86% using MGIT resistance as a reference. Conclusions: Phenotypic methods for testing ethionamide are imperfectly correlated, and the isolates with MIC of 5 mg/L have the intermediate resistance. A significant proportion of resistant TB cases are susceptible and eligible for ethionamide treatment. Resistance could be explained using only analysis of loci ethA, PfabG1, and inhA for most isolates in the Moscow region. The promoter mutation PfabG1 c(-15)t predicts resistance to ethionamide with high specificity but low sensitivity

    Information technologies in teaching humanitarian disciplines

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    The use of information technology in teaching humanitarian disciplines contributes to the formation of highly qualified, competitive specialists who can adapt to rapidly changing conditions, possessing a high level of development of critical and creative thinking, ready for professional self-development and self-improvement, for the implementation of reflection, capable of setting goals and systematically achieving them. The work actualizes the importance of information technology in the training of highly qualified competitive specialists capable of implementing professional activities at a high level. The purpose of the article is to analyze the experience of implementing information technologies in teaching humanitarian disciplines. Smart boards, multimedia installations, document cameras, electronic textbooks, electronic educational platforms and others were used as information technologies used in the teaching of the humanities. The study made it possible to reveal the influence of information technologies on the level of formation of students' competencies.El uso de la tecnología de la información en la enseñanza de disciplinas humanitarias contribuye a la formación de especialistas altamente calificados y competitivos que pueden adaptarse a condiciones rápidamente cambiantes, poseer un alto nivel de desarrollo del pensamiento crítico y creativo, listos para el autodesarrollo y la superación profesional. para la implementación de la reflexión, capaz de fijar metas y alcanzarlas de manera sistemática. El trabajo actualiza la importancia de la tecnología de la información en la formación de especialistas competitivos altamente calificados capaces de implementar actividades profesionales de alto nivel. El propósito del artículo es analizar la experiencia de implementar tecnologías de la información en la enseñanza de disciplinas humanitarias. Se utilizaron pizarrones inteligentes, instalaciones multimedia, cámaras de documentos, libros de texto electrónicos, plataformas educativas electrónicas y otros como tecnologías de la información utilizadas en la enseñanza de las humanidades. El estudio permitió revelar la influencia de las tecnologías de la información en el nivel de formación de las competencias de los estudiantes

    Bright Single-Photon Sources for the Telecommunication O-Band Based on an InAs Quantum Dot with (In)GaAs Asymmetric Barriers in a Photonic Nanoantenna

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    We report on single-photon emitters for the telecommunication O-band (1260&ndash;1360 nm), which comprise an InAs/(In)GaAs quantum dot with asymmetric barriers, placed inside a semiconductor tapered nanocolumn acting as a photonic nanoantenna. The implemented design of the barriers provides a shift in the quantum dot radiation wavelength towards the O-band, while the nanoantenna collects the radiation and ensures its effective output. With non-resonant optical pumping, the average count rate of emitted single photons exceeds 10 MHz with the second-order correlation function g(2)(0) = 0.18 at 8 K

    The Flow Regimes of the Fuel Water Coal Slurries in the Canals of Spraying Devices

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    В статье рассмотрены вопросы течения высококонцентрированных водоугольных топливных суспензий при подаче их на сжигание через распыливающие устройства – форсунки. Исследованы режимы течения суспензий в тонких каналах распыливающих устройств. Установлено, что при течении ВУС по тонким каналам нарушается режим течения, что обусловлено взаимным влиянием геометрических размеров и параметров течения суспензии при организации ее сжигания в топочных камерах энергоустановок. Поэтому конструктивные размеры, особенно выходные диаметры отверстий форсунок, необходимо подбирать, учитывая полученные аналитические выражения, которые должны быть уточнены при проведении модельных и натурных экспериментов с конкретными типами ВУС постоянного составаThe article deals with the flow of highly concentrated water-coal fuel slurries (WCS) when they are added for the combustion through spraying devices – nozzles. The flow regimes of slurries in thin canals of spraying devices are studied. It is established that during the WCS flow through thin canals, the flow regime is violated, which is caused by the mutual influence of geometric dimensions and flow parameters of the slurries when it is burned in combustion chambers of power plants. Therefore, the design dimensions, especially the outlet diameters of the nozzle holes, must be selected, taking into account the obtained analytical expressions, which should be refined in carrying out model and full-scale experiments with specific types of WCS of constant compositio

    The Flow Regimes of the Fuel Water Coal Slurries in the Canals of Spraying Devices

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    В статье рассмотрены вопросы течения высококонцентрированных водоугольных топливных суспензий при подаче их на сжигание через распыливающие устройства – форсунки. Исследованы режимы течения суспензий в тонких каналах распыливающих устройств. Установлено, что при течении ВУС по тонким каналам нарушается режим течения, что обусловлено взаимным влиянием геометрических размеров и параметров течения суспензии при организации ее сжигания в топочных камерах энергоустановок. Поэтому конструктивные размеры, особенно выходные диаметры отверстий форсунок, необходимо подбирать, учитывая полученные аналитические выражения, которые должны быть уточнены при проведении модельных и натурных экспериментов с конкретными типами ВУС постоянного составаThe article deals with the flow of highly concentrated water-coal fuel slurries (WCS) when they are added for the combustion through spraying devices – nozzles. The flow regimes of slurries in thin canals of spraying devices are studied. It is established that during the WCS flow through thin canals, the flow regime is violated, which is caused by the mutual influence of geometric dimensions and flow parameters of the slurries when it is burned in combustion chambers of power plants. Therefore, the design dimensions, especially the outlet diameters of the nozzle holes, must be selected, taking into account the obtained analytical expressions, which should be refined in carrying out model and full-scale experiments with specific types of WCS of constant compositio

    Towards Bright Single-Photon Emission in Elliptical Micropillars

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    In recent years, single-photon sources (SPSs) based on the emission of a single semiconductor quantum dot (QD) have been actively developed. While the purity and indistinguishability of single photons are already close to ideal values, the high brightness of SPSs remains a challenge. The widely used resonant excitation with cross-polarization filtering usually leads to at least a two-fold reduction in the single-photon counts rate, since single-photon emission is usually unpolarized, or its polarization state is close to that of the exciting laser. One of the solutions is the use of polarization-selective microcavities, which allows one to redirect most of the QD emission to a specific polarization determined by the optical mode of the microcavity. In the present work, elliptical micropillars with distributed Bragg reflectors are investigated theoretically and experimentally as a promising design of such polarization-selective microcavities. The impact of ellipticity, ellipse area and verticality of the side walls on the splitting of the optical fundamental mode is investigated. The study of the near-field pattern allows us to detect the presence of higher-order optical modes, which are classified theoretically. The possibility of obtaining strongly polarized single-photon QD radiation associated with the short-wavelength fundamental cavity mode is shown

    Quantum dot lasers and relevant nanoheterostructures

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    Spectral and power characteristics of QD stripe lasers operating in two-state lasing regime have been studied in a wide range of operation conditions. It was demonstrated that neither self-heating nor increase of the homogeneous broadening are responsible for quenching of the ground-state lasing beyond the two-state lasing threshold. It was found that difference in electron and hole capture rates strongly affects light-current curve. Modulation p-type doping is shown to enhance the peak power of GS lasing transition. Microring and microdisk structures (D = 4-9 mu m) comprising 1.3 mu m InAs/InGaAs quantum dots have been fabricated and studied by mu-PL and NSOM. Ground-state lasing was achieved well above root temperature (up to 380 K). Effect of inner diameter on threshold characteristics was evaluated
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