Household determinants of biocontaminant exposures in Canadian homes

Exposure to biocontaminants, such as dust mites, animal dander, bacteria, and mold, is associated with a range of health effects. This study identified household characteristics associated with indoor biocontaminant loadings in four Canadian cities. Floor dust was collected in 290 Canadian homes in Edmonton, Halifax, Montreal, and Windsor. The dust samples were analyzed for house dust mite allergens (Der f 1 and Der p 1), cat allergen (Fel d 1), cockroach allergen (Bla g 1), beta-(1,3)-D-glucan, and endotoxin. Household information was obtained through questionnaires and home inspections. We performed univariate and multivariate analyses to identify household determinants of biocontaminant loadings and mold odor presence. We observed large regional variations for all biocontaminants, except for cockroach allergen. The ranges of the contaminants measured in loadings and concentrations were similar to that of previous Canadian studies. Household characteristics including presence of carpeting, low floor cleaning frequency, older home age, presence of pets, and indoor relative humidity above 45% were positively associated with the presence of multiple indoor biocontaminants. High floor cleaning frequency and use of dehumidifiers were negatively associated with the presence of multiple indoor biocontaminants. Mold odor was positively associated with older home age, past water damage, and visible mold growth

Residential heating with wood and coal: health impacts and policy options in Europe and North America

Residential heating with wood and coal is an important source of ambient (outdoor) air pollution; it can also cause substantial indoor air pollution through either direct exposure or infiltration from outside. Evidence links emissions from wood and coal heating to serious health effects such as illness and death from respiratory and cardiovascular diseases. Burning wood and coal also emits carcinogenic compounds. The report describes the health effects of and policy options for dealing with residential heating with wood and coal in Europe and the United States. The results presented indicate that it will be difficult to tackle problems with outdoor air pollution in many parts of the world without addressing this source sector. National, regional and local administrations, politicians and the public at large need a better understanding of the role of wood biomass heating as a major source of harmful outdoor air pollutants (especially fine particles). This report is intended to help increase such an understanding

Predictors of Indoor Air Concentrations in Smoking and Non-Smoking Residences

Indoor concentrations of air pollutants (benzene, toluene, formaldehyde, acetaldehyde, acrolein, nitrogen dioxide, particulate matter, elemental carbon and ozone) were measured in residences in Regina, Saskatchewan, Canada. Data were collected in 106 homes in winter and 111 homes in summer of 2007, with 71 homes participating in both seasons. In addition, data for relative humidity, temperature, air exchange rates, housing characteristics and occupants’ activities during sampling were collected. Multiple linear regression analysis was used to construct season-specific models for the air pollutants. Where smoking was a major contributor to indoor concentrations, separate models were constructed for all homes and for those homes with no cigarette smoke exposure. The housing characteristics and occupants’ activities investigated in this study explained between 11% and 53% of the variability in indoor air pollutant concentrations, with ventilation, age of home and attached garage being important predictors for many pollutants

Quantifying the health impacts of ambient air pollutants: recommendations of a WHO/Europe project

© 2015, The Author(s). Objective: Quantitative estimates of air pollution health impacts have become an increasingly critical input to policy decisions. The WHO project “Health risks of air pollution in Europe—HRAPIE” was implemented to provide the evidence-based concentration–response functions for quantifying air pollution health impacts to support the 2013 revision of the air quality policy for the European Union (EU). Methods: A group of experts convened by WHO Regional Office for Europe reviewed the accumulated primary research evidence together with some commissioned reviews and recommended concentration–response functions for air pollutant–health outcome pairs for which there was sufficient evidence for a causal association. Results: The concentration–response functions link several indicators of mortality and morbidity with short- and long-term exposure to particulate matter, ozone and nitrogen dioxide. The project also provides guidance on the use of these functions and associated baseline health information in the cost–benefit analysis. Conclusions: The project results provide the scientific basis for formulating policy actions to improve air quality and thereby reduce the burden of disease associated with air pollution in Europe

Quantifying the health impacts of ambient air pollutants: recommendations of a WHO/Europe project.

OBJECTIVE: Quantitative estimates of air pollution health impacts have become an increasingly critical input to policy decisions. The WHO project "Health risks of air pollution in Europe--HRAPIE" was implemented to provide the evidence-based concentration-response functions for quantifying air pollution health impacts to support the 2013 revision of the air quality policy for the European Union (EU). METHODS: A group of experts convened by WHO Regional Office for Europe reviewed the accumulated primary research evidence together with some commissioned reviews and recommended concentration-response functions for air pollutant-health outcome pairs for which there was sufficient evidence for a causal association. RESULTS: The concentration-response functions link several indicators of mortality and morbidity with short- and long-term exposure to particulate matter, ozone and nitrogen dioxide. The project also provides guidance on the use of these functions and associated baseline health information in the cost-benefit analysis. CONCLUSIONS: The project results provide the scientific basis for formulating policy actions to improve air quality and thereby reduce the burden of disease associated with air pollution in Europe

Serge Tousignant : jeux d'espaces, jeux de regards : le catalogue

L'exposition qui fait l'objet de ce catalogue a malheureusement été annulée à cause de la pandémie, mais elle aurait dû se tenir au Carrefour des arts et des sciences de l’Université de Montréal du 8 avril au 12 juin 2020.Catalogue d'exposition préparé à l'hiver 2020 dans le cadre du cours HAR 6080 / MSL 6509 : Muséologie et histoire de l'art, donné par la professeure Christine Bernier.Catalogue préparé sous la direction de Christine Bernie

Response to: Premature deaths attributed to ambient air pollutants: let us interpret the Robins-Greenland theorem correctly.

We thank Morfeld and Erren for their continued interest in the WHO Health risks of air pollution in Europe (HRAPIE) report (WHO Regional Office for Europe 2013). The key point of contention seems to be the interpretation of the numbers of ‘premature deaths’ associated with air pollution (or any other) exposure. In the IJPH article that is at the basis of the two letters written by Morfeld and Erren (Heroux et al. 2015), the limitations of calculating and using numbers of ‘premature deaths’ were perhaps not sufficiently explained. We elaborated on this in our first response (Heroux et al. 2016), arguing that the criticized calculation of ‘premature deaths’ produces a reasonable albeit ambiguous estimate, for which reason calculation of years of life lost is a more preferable approach. We would like to point out that the HRAPIE report really is about identification of concentration–response functions to be further used in health impact assessments, and therefore did not pretend to provide a discussion of estimating etiologic fractions. Morfeld and Erren single out the one numerical example of an impact assessment given in our paper, and that example was not a result from the HRAPIE work itself but a quote from a report from the European Commission (2013). We never intended to give the impression that these numbers refer to individually identifiable, attributable deaths, however.Peer reviewe

European Collaborative Action - Urban Air, Indoor Environment and Human Exposure, Report No 30, Framework for health-based ventilation guidelines in Europe

The present report describes the findings and recommendations of the HealthVent (Health-based ventilation guidelines for Europe) project that funded by the European Commission’s Directorate General for Health and Consumers in the framework of the Second Programme of Community Action in the Field of Health (2008-2013). HealthVent developed a framework for health-based ventilation guidelines for public and residential buildings in Europe and assessed the consequences of implementing these guidelines, bearing in mind future trends in the built environment, including energy efficiency and environmental sustainability issues.JRC.F.2-Consumer Products Safet

A review of the experimental evidence on the toxicokinetics of carbon monoxide: the potential role of pathophysiology among susceptible groups

Abstract Background Acute high level carbon monoxide (CO) exposure can cause immediate cardio-respiratory arrest in anyone, but the effects of lower level exposures in susceptible persons are less well known. The percentage of CO-bound hemoglobin in blood (carboxyhemoglobin; COHb) is a marker of exposure and potential health outcomes. Indoor air quality guidelines developed by the World Health Organization and Health Canada, among others, are set so that CO exposure does not lead to COHb levels above 2.0%, a target based on experimental evidence on toxicodynamic relationships between COHb and cardiac performance among persons with cardiovascular disease (CVD). The guidelines do not consider the role of pathophysiological influences on toxicokinetic relationships. Physiological deficits that contribute to increased CO uptake, decreased CO elimination, and increased COHb formation can alter relationships between CO exposures and resulting COHb levels, and consequently, the severity of outcomes. Following three fatalities attributed to CO in a long-term care facility (LTCF), we queried whether pathologies other than CVD could alter CO-COHb relationships. Our primary objective was to inform susceptibility-specific modeling that accounts for physiological deficits that may alter CO-COHb relationships, ultimately to better inform CO management in LTCFs. Methods We reviewed experimental studies investigating relationships between CO, COHb, and outcomes related to health or physiological outcomes among healthy persons, persons with CVD, and six additional physiologically susceptible groups considered relevant to LTCF residents: persons with chronic obstructive pulmonary disease (COPD), anemia, cerebrovascular disease (CBD), heart failure, multiple co-morbidities, and persons of older age (≥ 60 years). Results We identified 54 studies published since 1946. Six studies investigated toxicokinetics among healthy persons, and the remaining investigated toxicodynamics, mainly among healthy persons and persons with CVD. We identified one study each of CO dynamics in persons with COPD, anemia and persons of older age, and no studies of persons with CBD, heart failure, or multiple co-morbidities. Considerable heterogeneity existed for exposure scenarios and outcomes investigated. Conclusions Limited experimental human evidence on the effects of physiological deficits relevant to CO kinetics exists to support indoor air CO guidelines. Both experimentation and modeling are needed to assess how physiological deficits influence the CO-COHb relationship, particularly at sub-acute exposures relevant to indoor environments. Such evidence would better inform indoor air quality guidelines and CO management in indoor settings where susceptible groups are housed

Expanding perspectives on the poverty trap for smallholder farmers in Tanzania : the role of rural input supply chains

Smallholder farmers across rural landscapes remain trapped in a vicious cycle of endemic poverty where interconnected challenges limit their ability to improve their livelihoods. Our study of smallholder farmers’ relationships with suppliers and several stakeholders across the Tanzanian rural agro-input supply chain offers an extended perspective on the persistence of endemic poverty and broadens the discussion on the future of sustainable food production and smallholder livelihoods. Through interviews and focus groups, we use a grounded theory methodology to develop a systemic approach to understanding the complexities of this landscape as related to smallholder agro-input sourcing activities. Our causal loop diagram framework provides a unique perspective on the poverty trap experienced by smallholder farmers in this context. Our findings may be useful in targeting practical and sustainable directions towards overcoming the poverty trap, ultimately enabling smallholders to increase wealth and improve their livelihoods through sustainable practices