191 research outputs found
A importancia do RH na implantação da gestão por competência na CREDIP
Artigo apresentado à Fundação Universidade Federal de Rondônia, Campus de Cacoal, como requisito parcial para obtenção do Título de Bacharel em Administração. Orientador: Prof. Me. Geraldo da Silva CorreiaPara ser bem sucedida, uma organização deve ser capaz de gerenciar as competências de seus colaboradores, mapeando, identificando e desenvolvendo as que são essenciais para seus processos de negócio e de trabalho. O modelo Gestão por Competências vem sendo inserido nas organizações como fator essencial ao atendimento de seus objetivos e tem surgido fortemente ligado à área de recursos humanos, significando uma renovação no papel prestado por essa área dentro das organizações. O presente artigo buscou, através de pesquisa exploratória, qualitativa, descrever a implantação do modelo de Gestão por Competências na Credip, relatando o processo de definição das competências, as dificuldades enfrentadas, as perspectivas em relação à gestão e também procurou demonstrar a importância do RH como elo de integração entre as estratégias e as competências individuais. Pode-se observar a participação ativa do RH no processo de implantação da Gestão por competências na Credip, que se encontra na etapa de identificação das competências dos colaboradores, que gerará o feedback entre gerência e colaboradores, possibilitando então o desenvolvimento dos mesmos. Os colaboradores no início acharam complexo o modelo, mas à medida que compreendem o processo, aceitam-no e passam a se comprometer com o mesmo. Caberá,
portanto, à cúpula da cooperativa zelar pela continuidade do processo que, até então, tem obtido êxito em todas as etapas
Violência doméstica contra crianças e adolescentes
Trabalho de Conclusão de Curso apresentado à Fundação Universidade Federal de Rondônia - Campus de Cacoal, como requisito parcial para obtenção do título de Bacharel em Direito. Orientador Prof. Me. Gilson Tetsuo
Miyakava.A violência doméstica é uma forma de agressão praticada dentro da instituição familiar, a dominação do mais fraco pelo mais forte, distingue-se da violência em si por ser praticada por pessoas que gozam do afeto e da confiança da vítima. O abusador utiliza-se de várias formas para atingir seus objetivos, sendo estas: a negligência, a violência psicológica, física e sexual. Na pesquisa realizada no Município de Nova Brasilândia do Oeste RO, foi analisado o perfil do agressor e suas formas de agir, nos casos estudados destaca-se quem são os principais abusadores e suas vítimas. Nos últimos anos houve uma grande preocupação tanto da sociedade quanto do Estado em proporcionar uma maior proteção à criança e ao adolescente, sendo criada
diversas Leis de proteção aos mesmos, tendo no bojo da Constituição da República Federativa do Brasil de 1988 e na Lei 8.069/90 - Estatuto da Criança e do Adolescente, seu marco maior, consolidando à criança e o adolescente como sujeito de direitos e consequentemente garantindo-lhes respeito na condição de pessoa humana. A sociedade por sua vez se mobiliza cada vez mais para a diminuição da violência nos lares, com a criação de organizações não governamentais, de apoio não somente à criança e ao adolescente, mas a toda instituição familiar
South-south cooperation in Lula da Silva administration’s foreign policy
O objetivo deste trabalho é discutir a política de cooperação Sul-Sul voltada para o desenvolvimento e executada pelo Brasil entre 2003 e 2010. O artigo discute até que ponto essa nova proposta de cooperação realizou-se efetivamente dentro de uma lógica sem condicionalidades, contrapondo-se às formas tradicionais marcadas por imposições por parte dos países doadores. Analisamos como essa cooperação foi
utilizada durante o governo do presidente Lula da Silva, como parte de sua estratégia de inserção internacional e instrumento para garantir o apoio de aliados.El objetivo de este trabajo es discutir la política de Cooperación Sur-Sur centrada en el tema del desarrollo, e implementada por Brasil entre 2003 y 2010. El artículo cuestiona en qué medida esta nueva propuesta de cooperación siguió efectivamente una lógica sin condicionamientos, en oposición a las formas tradicionales caracterizadas por las imposiciones hechas por los países donantes. El análisis busca verificar cómo la administración del presidente Lula da Silva utilizó esta cooperación como parte de su estrategia de inserción internacional y como herramienta para asegurar el apoyo de los aliados.Fil: Menezes, Roberto Goulart.
Universidad de Brasilia.Fil: Mariano, Karina Lilia P.
Universidad Estatal PaulistaFil: Klemig, Mariana Costa Guimarães.
Universidad de Brasilia
A new reconstruction method in the Fourier domain for 3D positron emission tomography
International audienc
Insecticide resistance in Aedes aegypti populations from Ceará, Brazil
<p>Abstract</p> <p>Background</p> <p>Organophosphates and pyrethroids are used widely in Brazil to control <it>Aedes aegypti</it>, the main vector of dengue viruses, under the auspices of the National Programme for Dengue Control. Resistance to these insecticides is widespread throughout Brazil. In Ceará the vector is present in 98% of districts and resistance to temephos has been reported previously. Here we measure resistance to temephos and the pyrethroid cypermethrin in three populations from Ceará and use biochemical and molecular assays to characterise resistance mechanisms.</p> <p>Results</p> <p>Resistance to temephos varied widely across the three studied populations, with resistance ratios (RR<sub>95</sub>) of 7.2, 30 and 192.7 in Juazeiro do Norte, Barbalha and Crato respectively. The high levels of resistance detected in Barbalha and Crato (RR<sub>95 </sub>≥ 30) imply a reduction of temephos efficacy, and indeed in simulated field tests reduced effectiveness was observed for the Barbalha population. Two populations (Crato and Barbalha) were also resistant to cypermethrin, whilst Juazeiro do Norte showed only an altered susceptibility. The <it>Ile1011Met kdr </it>mutation was detected in all three populations and <it>Val1016Ile </it>in Crato and Juazeiro do Norte. <it>1011Met </it>was significantly associated with resistance to cypermethrin in the Crato population. Biochemical tests showed that only the activity of esterases and GSTs, among the tested detoxification enzymes, was altered in these populations when compared with the Rockefeller strain.</p> <p>Conclusions</p> <p>Our results demonstrate that two <it>A. aegypti </it>populations from Ceará are under strong selection pressure by temephos, compromising the field effectiveness of this organophosphate. Our results also provide evidence that the process of reducing resistance to this larvicide in the field is difficult and slow and may require more than seven years for reversal. In addition, we show resistance to cypermethrin in two of the three populations studied, and for the first time the presence of the allele <it>1016Ile </it>in mosquito populations from northeastern Brazil. A significant association between <it>1011M</it>et and resistance was observed in one of the populations. Target-site mechanisms seem not to be implicated in temephos resistance, reinforcing the idea that for the studied populations, detoxification enzymes most likely play a major role in the resistance to this insecticide.</p
A preliminary analysis of the reduction of chemotherapy waste in the treatment of cancer with centralization of drug preparation
Convalescent plasma for COVID-19 in hospitalised patients : an open-label, randomised clinical trial
Background: The effects of convalescent plasma (CP) therapy in hospitalised patients with coronavirus disease 2019 (COVID-19) remain uncertain. This study investigates the effect of CP on clinical improvement in these patients. Methods: This is an investigator-initiated, randomised, parallel arm, open-label, superiority clinical trial. Patients were randomly (1:1) assigned to two infusions of CP plus standard of care (SOC) or SOC alone. The primary outcome was the proportion of patients with clinical improvement 28 days after enrolment. Results: A total of 160 (80 in each arm) patients (66.3% critically ill, 33.7% severely ill) completed the trial. The median (interquartile range (IQR)) age was 60.5 (48–68) years; 58.1% were male and the median (IQR) time from symptom onset to randomisation was 10 (8–12) days. Neutralising antibody titres >1:80 were present in 133 (83.1%) patients at baseline. The proportion of patients with clinical improvement on day 28 was 61.3% in the CP+SOC group and 65.0% in the SOC group (difference −3.7%, 95% CI −18.8–11.3%). The results were similar in the severe and critically ill subgroups. There was no significant difference between CP+SOC and SOC groups in pre-specified secondary outcomes, including 28-day mortality, days alive and free of respiratory support and duration of invasive ventilatory support. Inflammatory and other laboratory marker values on days 3, 7 and 14 were similar between groups. Conclusions: CP+SOC did not result in a higher proportion of clinical improvement on day 28 in hospitalised patients with COVID-19 compared to SOC alone
Assessment of Translocator Protein Density, as Marker of Neuroinflammation, in Major Depressive Disorder: A Pilot, Multicenter, Comparative, Controlled, Brain PET Study (INFLADEP Study)
Background: Major depressive disorder (MDD) is a serious public health problem with high lifetime prevalence (4.4–20%) in the general population. The monoamine hypothesis is the most widespread etiological theory of MDD. Also, recent scientific data has emphasized the importance of immuno-inflammatory pathways in the pathophysiology of MDD. The lack of data on the magnitude of brain neuroinflammation in MDD is the main limitation of this inflammatory hypothesis. Our team has previously demonstrated the relevance of [18F] DPA-714 as a neuroinflammation biomarker in humans. We formulated the following hypotheses for the current study: (i) Neuroinflammation in MDD can be measured by [18F] DPA-714; (ii) its levels are associated with clinical severity; (iii) it is accompanied by anatomical and functional alterations within the frontal-subcortical circuits; (iv) it is a marker of treatment resistance.Methods: Depressed patients will be recruited throughout 4 centers (Bordeaux, Montpellier, Tours, and Toulouse) of the French network from 13 expert centers for resistant depression. The patient population will be divided into 3 groups: (i) experimental group—patients with current MDD (n = 20), (ii) remitted depressed group—patients in remission but still being treated (n = 20); and, (iii) control group without any history of MDD (n = 20). The primary objective will be to compare PET data (i.e., distribution pattern of neuroinflammation) between the currently depressed group and the control group. Secondary objectives will be to: (i) compare neuroinflammation across groups (currently depressed group vs. remitted depressed group vs. control group); (ii) correlate neuroinflammation with clinical severity across groups; (iii) correlate neuroinflammation with MRI parameters for structural and functional integrity across groups; (iv) correlate neuroinflammation and peripheral markers of inflammation across groups.Discussion: This study will assess the effects of antidepressants on neuroinflammation as well as its role in the treatment response. It will contribute to clarify the putative relationships between neuroinflammation quantified by brain neuroimaging techniques and peripheral markers of inflammation. Lastly, it is expected to open innovative and promising therapeutic perspectives based on anti-inflammatory strategies for the management of treatment-resistant forms of MDD commonly seen in clinical practice.Clinical trial registration (reference: NCT03314155): https://www.clinicaltrials.gov/ct2/show/NCT03314155?term=neuroinflammation&cond=depression&cntry=FR&rank=
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