360 research outputs found

    Correction: New knowledge on the antiglycoxidative mechanism of chlorogenic acid

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    Correction for 'New knowledge on the antiglycoxidative mechanism of chlorogenic acid' by Beatriz Fernandez-Gomez et al., Food Funct., 2015, DOI: 10.1039/c5fo00194c

    Nurses' perceptions of patient safety culture : a mixed-methods study

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    There are relatively few qualitative studies concerning patient safety culture. We aimed to explore patient safety culture as perceived by the nursing staff in two public hospitals in Catalonia, Spain. A mixed-methods design was employed using a questionnaire, in-depth interviews, and non-participant observations. Sixty-two percent of the nursing staff rated patient safety as "Acceptable" but was not higher because of work pressure and lack of resources as perceived by staff. "Teamwork within units" had the highest rate of positive responses, and "Staffing" had the lowest rate. Emergency units showed more negative results than the other two units. Safety incidents are not always reported due to fear of punishment, reflecting a lack of positive safety culture. It is necessary to design and implement strategies that promote a positive culture to avoid punitive responses and apply and evaluate these changes

    Diagnosis of Education in values of students in the Master´s Degree of the UAEMéx. 2019

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    ArtículoEl objetivo de este trabajo es analizar los valores y la actitud en las que los estudiantes de la Maestría en Estudios para la Paz y el Desarrollo de la Facultad de Ciencias Políticas y Sociales de la UAEMéx enfrentan los conflictos en el aula, ya sea a través de la evasión, acomodación (complacencia), competición, negociación y la cooperación. Modelo que emplea Paco Cascón (2001) y a través de ello se vislumbran nuevas formas de hacer las paces, pues consideramos importante aprender a gestionar de manera positiva, creativa y pacífica los conflictos. Se emplea la investigación cuantitativa y documental para definir los valores, actitudes y estilos de afrontar el conflicto a través de indicadores de medición. Para la obtención de la información en campo, se aplicaron tres tipos diferentes de escalas de medición tipo Lickert con la finalidad de conocer cuáles valores tienen más arraigados los maestrantes, así como la actitud y el estilo de resolver sus conflictos en el aula. Los resultados más significativos fueron conocer si saben dialogar y obtuvimos que necesitan realizar esfuerzos para ser dialógicos. Respecto a los valores, los estudiantes respondieron que la honestidad era el más importante y en los resultados de las preguntas argumentaron que era el de justicia y el menos importante fue la creatividad. En los cinco estilos de afrontar el conflicto el más utilizado es la negociación dejando al estilo complaciente al final.Revista Cultura de Paz. Universidad Católica Particular en Loja, Ecuado

    Effect of Chitosan Edible Coating on the Biochemical and Physical Characteristics of Carp Fillet (Cyprinus carpio) Stored at −18ºC.

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    The effect of an edible coating (EC) with 1.5% chitosan as an additive, on common carp (Cyprinus carpio) fillet, was determined evaluating the biochemical, physicochemical, textural, microbiological, and nutritional characteristics periodically during its hydroperoxides content (HPC) (0.8324 nM hydroperoxides/mg of protein versus 0.5540 nM/mg with regard to the EC sample), as well as protein carbonyl content (PCC) (0.5860 nM versus 0.4743 nM of reactive carbonyl groups/mg of protein of noncoated material), keeping properties for a longer period of time, and a lower protein solubility (7.8 mg of supernatant protein/mg of total microbialgrowth,thecountwas2.2×10 CFU/gofsampleinmesophilesversus4.7×10 intheECsample.Theresultsindicatethat the use of EC added with chitosan maintains the quality of the product regarding lipid and protein oxidation until fourth month of storage, maintaining moisture content without variation for at least 3 months, and inhibits microbial growth up to 2 logarithmic units, during five months of frozen storage

    Phosphate, microbiota and ckd

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    Phosphate is a key uremic toxin associated with adverse outcomes. As chronic kidney disease (CKD) progresses, the kidney capacity to excrete excess dietary phosphate decreases, triggering compensatory endocrine responses that drive CKD-mineral and bone disorder (CKD-MBD). Eventu-ally, hyperphosphatemia develops, and low phosphate diet and phosphate binders are prescribed. Recent data have identified a potential role of the gut microbiota in mineral bone disorders. Thus, parathyroid hormone (PTH) only caused bone loss in mice whose microbiota was enriched in the Th17 cell-inducing taxa segmented filamentous bacteria. Furthermore, the microbiota was required for PTH to stimulate bone formation and increase bone mass, and this was dependent on bacterial production of the short-chain fatty acid butyrate. We review current knowledge on the relationship between phosphate, microbiota and CKD-MBD. Topics include microbial bioactive compounds of special interest in CKD, the impact of dietary phosphate and phosphate binders on the gut microbiota, the modulation of CKD-MBD by the microbiota and the potential therapeutic use of microbiota to treat CKD-MBD through the clinical translation of concepts from other fields of science such as the optimization of phosphorus utilization and the use of phosphate-accumulating organisms.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 860329, FIS/Fondos FEDER (PI18/01366, PI20/00744, PI19/00815, DTS18/00032, ERA-PerMed-JTC2018 (KIDNEY ATTACK AC18/00064 and PERSTIGAN AC18/00071, ISCIII-RETIC REDinREN RD016/0009), Sociedad Española de Nefrología, FRIAT, Comunidad de Madrid en Biomedicina B2017/BMD-3686 CIFRA2-C

    Effect of Chia Seed on Physicochemical and Sensory Characteristics of Common Carp Restructured as Functional Food

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    Physicochemical and sensory characteristics of restructured meat of common carp (Cyprinus carpio) fortified with 0-8 g/100 g of chia seed flour (CSF) was evaluated. It had a higher nutritional value (higher fibre content and protein retention] (p < 0.05) and better cooking characteristics (higher cooking yield and moisture retention) (p < 0.05) than the control. The colour (a*, b*) increased; lightness and whiteness index decrease (p < 0.05). Hardness increase (p < 0.05) occurred because of CSF addition. Differential scanning calorimetry showed that fibre fortification did not interfere with the thermal transitions of the restructured meat. No significant differences were detected with the preference test scores of 4% or 8% CSF compared with the control. Restructured (4%-8% CSF) had a higher content of fibre and fat, which could be linoleic and linolenic acid, and an increase in the content of protein compared with those of commercial products, among had 1.62 and 2.25 mg AGE/g. Therefore, the restructured properties of common carp were governed by CSF addition

    Identification of Importin 8 (IPO8) as the most accurate reference gene for the clinicopathological analysis of lung specimens

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    <p>Abstract</p> <p>Background</p> <p>The accurate normalization of differentially expressed genes in lung cancer is essential for the identification of novel therapeutic targets and biomarkers by real time RT-PCR and microarrays. Although classical "housekeeping" genes, such as GAPDH, HPRT1, and beta-actin have been widely used in the past, their accuracy as reference genes for lung tissues has not been proven.</p> <p>Results</p> <p>We have conducted a thorough analysis of a panel of 16 candidate reference genes for lung specimens and lung cell lines. Gene expression was measured by quantitative real time RT-PCR and expression stability was analyzed with the softwares <it>GeNorm </it>and <it>NormFinder</it>, mean of |ΔCt| (= |Ct Normal-Ct tumor|) ± SEM, and correlation coefficients among genes. Systematic comparison between candidates led us to the identification of a subset of suitable reference genes for clinical samples: IPO8, ACTB, POLR2A, 18S, and PPIA. Further analysis showed that IPO8 had a very low mean of |ΔCt| (0.70 ± 0.09), with no statistically significant differences between normal and malignant samples and with excellent expression stability.</p> <p>Conclusion</p> <p>Our data show that IPO8 is the most accurate reference gene for clinical lung specimens. In addition, we demonstrate that the commonly used genes GAPDH and HPRT1 are inappropriate to normalize data derived from lung biopsies, although they are suitable as reference genes for lung cell lines. We thus propose IPO8 as a novel reference gene for lung cancer samples.</p

    A Model for Electrodialytic Treatment of Lithium-Ion Batteries

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    New recycling processes for secondary batteries are needed to achieve sustainable use of natural resources. Indeed, many components in lithium ion batteries, such as cobalt and graphite, are in the European Union’s “Critical Raw Materials” list. Electrodialytic treatment of disposed lithium-ion batteries is a pioneer proposal for the selective recovery of some of these relevant elements. In this work, a model for the electrochemical technology of disposed batteries implemented using COMSOL Multiphysics is presented. The main aim of this model is the optimization of the extraction of valuable components from spent batteries and the prediction of experimental results, which entails a better understanding of the different process involved. The model is based on the Nernst-Planck- Poisson system of equations coupled with the local chemical equilibrium conditions. The model uses multi-scale discretization of the different components; including the assumed well-stirred compartments, the ion-exchange membranes and the diffuse double-layer at the surface of the membranes. Different cell configuration has been tested, and results were compared to experimental data for model validation.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. The authors acknowledge the financial support from the "Plan Propio de Investigación de la Universidad de Málaga" with project numbers PPIT.UMA.D1, PPIT.UMA.B1.2017/20 and PPIT.UMA.B5.2018/17. This work has also received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 778045

    EFECTO DE LA LEVADURA ENRIQUECIDA CON SELENIO Y SELENITO DE SODIO EN LA DIETA DE CERDOS EN FINALIZACIÓN SOBRE EL CONTENIDO DE GRASA INTRAMUSCULAR Y ACIDOS GRASOS

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    Se determinó el efecto de la adición de selenio (Se) orgánico (selenito de sodio) e inorgánico (levadura enriquecida con selenio) en el alimento sobre el contenido de grasa intramuscular y ácidos grasos músculos semimembranoso y longissimus dors en cerdos en finalización. Los animales (n=48) derivados de la cruza (Pic 337x (Camborough 22) fueron alimentados a base de maíz molido y pasta de soya. La dieta fue fortificada con Se en tres tratamientos, T0=0%, T1= 0.45ppm de levadura T2=0.45ppm selenito de sodio. Los animales fueron sacrificados a un peso de 110±5kg. Se determinó grasa bajo el método ISO-1443 modificado y los ácidos grasos por cromatografía de gases. Se realizó un ANOVA mediante arreglo factorial 3x2, las variables de estudio fueron, fuente de Se: 0, 0.45 ppm de Se orgánico y 0.45 de Se inorgánico, sexo: machos y hembras. Hubo efecto de tratamiento (P 0.05) para los ácidos grasos en el músculo longisimus dorsi, aumentando la concentración de C16, C18, C18:2; en el músculo semimembranosus no hubo diferencias con respecto a los tratamientos, para la variable sexo se demostró que los machos fueron los más pesados al sacrificio
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