End-User Development (EUD) : desenvolvimento pelo usuário final: conceitos, estratégias e casos de adoção : relatório de pesquisa

Pesquisa realizada com financiamento do Ministério da Ciência, Tecnologia, Inovações e Comunicações, Projeto de Cooperação “Aprimoramento do Framework de Soluções de Tecnologia da Informação”.Ministério da Ciência, Tecnologia, Inovações e Comunicaçõe

Desenvolvimento descentralizado por meio de End-User Development : avaliação tecnológica : relatório de pesquisa

Pesquisa realizada com financiamento do Ministério da Ciência, Tecnologia, Inovações e Comunicações, Projeto de Cooperação “Aprimoramento do Framework de Soluções de Tecnologia da Informação”. Ministério da Ciência, Tecnologia, Inovações e Comunicaçõe

Adolescents’ sleep quality during the COVID-19 pandemic

Objective: To assess the sleep quality of Brazilian adolescents during the COVID-19 pandemic. Methods: Observational, analytical, cross-sectional study with data from a questionnaire on individual characteristics and health, Epworth Sleepiness Scale and the Pittsburgh Sleep Quality Index (PSQI). 153 adolescents participated - 61.4% females, 38.6% males, aged 13 to 18 years, enrolled at school. Results: 58.2% worsened their sleep quality during the pandemic. In the PSQI, 22 (14.4%) had a good, 104 (68%), a poor sleep quality, 27 (17.6%), suggestive of sleep disorders. Excessive daytime sleepiness occurred in 44.4% of the students. Significant associations appeared between sleep and decreased school motivation (p = 0.005), and between sleep and sex (p = 0.015). The pandemic affected more the females - 25.5% reported worse sleep quality, 67% had PSQI scores suggestive of sleep disorders; 46 (30.1%) students reported stress, anxiety, sadness -76.1% were girls. Discussion: Adolescents had impaired sleep during the COVID-19 pandemic, reinforcing their sleep must be assessed in critical periods

Obesidade e as Intervenções Governamentais: análise de macrocontigências e metacontigencias

Resumo: este trabalho apresenta a visão analítico-comportamental nos três níveis de seleção de fatores relacionados à obesidade. São discutidos como cada nível de seleção determina comportamentos que produzem obesidade. A insuficiência da consideração da obesidade de modo individual é destacada. A atual epidemia da obesidade exige a consideração de fenômenos comportamentais no terceiro nível da cultura. Por fim, são discutidos políticas públicas que tentam intervir a partir da alteração de práticas culturais para alterar o atual status da epidemia da obesidade. Palavras-chave: Obesidade. Políticas Publicas. Práticas Culturais. Macrocontingências. Metacontingências

Schinus terebinthifolius leaf extract causes midgut damage, interfering with survival and development of Aedes aegypti larvae

In this study, a leaf extract from Schinus terebinthifolius was evaluated for effects on survival, development, and midgut of A. aegypti fourth instar larvae (L4), as well as for toxic effect on Artemia salina. Leaf extract was obtained using 0.15 M NaCl and evaluated for phytochemical composition and lectin activity. Early L4 larvae were incubated with the extract (0.3–1.35%, w/v) for 8 days, in presence or absence of food. Polymeric proanthocyanidins, hydrolysable tannins, heterosid and aglycone flavonoids, cinnamic acid derivatives, traces of steroids, and lectin activity were detected in the extract, which killed the larvae at an LC50 of 0.62% (unfed larvae) and 1.03% (fed larvae). Further, the larvae incubated with the extract reacted by eliminating the gut content. No larvae reached the pupal stage in treatments at concentrations between 0.5% and 1.35%, while in the control (fed larvae), 61.7% of individuals emerged as adults. The extract (1.0%) promoted intense disorganization of larval midgut epithelium, including deformation and hypertrophy of cells, disruption of microvilli, and vacuolization of cytoplasms, affecting digestive, enteroendocrine, regenerative, and proliferating cells. In addition, cells with fragmented DNA were observed. Separation of extract components by solid phase extraction revealed that cinnamic acid derivatives and flavonoids are involved in larvicidal effect of the extract, being the first most efficient in a short time after larvae treatment. The lectin present in the extract was isolated, but did not show deleterious effects on larvae. The extract and cinnamic acid derivatives were toxic to A. salina nauplii, while the flavonoids showed low toxicity. S. terebinthifolius leaf extract caused damage to the midgut of A. aegypti larvae, interfering with survival and development. The larvicidal effect of the extract can be attributed to cinnamic acid derivatives and flavonoids. The data obtained using A. salina indicates that caution should be used when employing this extract as a larvicidal agent

Prevalence of hepatitis B and hepatitis C among diabetes mellitus type 2 individuals

Diabetes mellitus type 2 (DM2) patients have higher risk to be infected with parenterally transmitted viruses, like hepatitis B or C virus. This study aims to determine HBV and HCV infection prevalence in DM2 patients from Northeast and Southeast Brazil. A total of 537 DM2 patients were included, 194 (36.12%) males and 343 (63.87%) females, with mean age of 57.13 +/- 11.49 years. HBV and HCV markers were determined using serological and molecular analysis, and risk factors were evaluated in a subgroup from Southeast (n = 84). Two HBV acute (HBsAg+/anti-HBc-) and one HBV chronic case (HBsAg+/anti-HBc+) were found. Six individuals (1.1%) were isolated anti-HBc, 37 (6.9%) had HBV infection resolved (anti-HBc+/anti-HBs+), 40 (7.4%) were considered HBV vaccinated (anti-HBc-/anti-HBs+). Thirteen patients (2.42%) had anti-HCV and 7 of them were HCV RNA+. In the subgroup, anti-HBc positivity was associated to age and anti-HCV positivity was associated to age, time of diabetes diagnosis, total bilirubin, indirect bilirubin, alkaline phosphatase at bivariate analysis, but none of them was statistically significant at multivariate analysis. As conclusion, low prevalence of HBV and high prevalence HCV was found in DM2 patients142CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPFundacao de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ)Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ); Brazilian National Counsel of Technological and Scientific Development (CNPq)National Council for Scientific and Technological Development (CNPq); Coordination of Improvement of Higher Level Personnel; Oswaldo Cruz Foundation (FIOCRUZ

Impaired chair-to-bed transfer ability leads to longer hospital stays among elderly patients

BACKGROUND: The study objectives were to identify the main predictive factors for long hospital stays and to propose new and improved methods of risk assessment. METHODS: This prospective cohort study was conducted in the clinics and surgical wards of a tertiary hospital and involved 523 elderly patients over 60 years of age. Demographic, clinical, functional, and cognitive characteristics assessed between 48 and 72 h after admission were analyzed to investigate correlations with lengths of stay greater than 10 days. Univariate and multivariate analyses were performed, and in the final model, long-term probability scores were estimated for each variable. RESULTS: Of the 523 patients studied, 33 (6.3%) remained hospitalized for more than 10 days. Multiple regression analysis revealed that both the presence of diabetes and the inability to perform chair-to-bed transfers (Barthel Index) remained significant risk predictors. Diabetes doubled the risk of prolonged hospital stays, while a chair-to-bed transfer score of 0 or 5 led to an eight-fold increase in risk. CONCLUSIONS: In this study, we propose an easy method that can be used, after external validation, to screen for long-term risk (using diabetes and bed/chair transfer) as a first step in identifying hospitalized elderly patients who will require comprehensive assessment to guide prevention plans and rehabilitation programs

AVALIAÇÃO DE EVENTOS ANTECEDENTES E SUBSEQUENTES A COMPORTAMENTOS ADEQUADOS E INADEQUADOS NA INTERAÇÃO PROFESSOR-ALUNO

The student-teacher interaction is a determinant aspect of learning in a classroom. The objective of this study was to conduct a functional evaluation of student-teacher interactions, in the classroom, in a municipal school with high levels of violence. Six students, aged between 9 and 16 years, participated in the study. They were 6th and 8th grade middle school students and they were assigned to two groups: Disciplined and Undisciplined. Ten teachers also participated, 9 of which were women and one man. The interactions between participants were recorded on camera. Researchers analyzed the videos by categorizing behaviors from students as adequate or inadequate, and recording the antecedents and subsequent events of each behavior. Results indicated no differences in emission of appropriate behaviors between students from the Disciplined and the Undisciplined groups. Few situations were observed in which the teacher presented events subsequent to the students’ behavior. When there were subsequent events these were more frequent for the adequate behavior of the members of the Disciplined Group and inadequate for the behavior of the members of the Undisciplined Group. Possible relationships between antecedent events, subsequent events and appropriate and inappropriate behaviors are discussed. It is suggested that teachers need to be trained in order to be able to identify functional relationships and intervene in the behavior of their students, thus favoring the emission of appropriate behaviors. We also suggest to conducting other research that investigates working conditions and environmental events that determine or limit teachers’ ability to intervene in their students’ behavior.Keywords: evaluating analysis; student-teacher interaction; adequate behavior; inadequate behavior.A interação professor-aluno é um aspecto determinante para aprendizagem em sala de aula. O objetivo deste estudo foi realizar a avaliação funcional da interação professor-aluno em sala de aula, em uma escola municipal com alto índice de violência. Participaram deste estudo seis estudantes com idades entre 9 a 16 anos, do 6o ao 8o ano do ensino fundamental, que compuseram dois grupos: Disciplinados e Indisciplinados; além de 10 professores, sendo nove mulheres e um homem. As interações entre os participantes foram registradas em vídeo. Pesquisadores analisaram os vídeos categorizando os comportamentos dos alunos como adequados e inadequados, registrando eventos anteriores e subsequentes desses comportamentos a partir de categorias de respostas dos professores. Os resultados indicam que não houve diferença de emissão de comportamentos apropriados entre alunos do Grupo Disciplinados ou do Grupo Indisciplinados. Já os comportamentos inadequados são mais frequentes entre os alunos do Grupo Indisciplinados. Foram observadas poucas situações nas quais o professor apresentava eventos subsequentes aos comportamentos dos alunos. Quando havia eventos subsequentes esses eram mais comuns para o comportamento adequado dos membros do Grupo Disciplinado e inadequados para o comportamento dos membros do Grupo Indisciplinado. Discute-se possíveis relações entre os eventos antecedentes, eventos subsequentes e comportamentos adequados e inadequados. Sugere-se treinamento aos professores para identificar relações funcionais e intervirem no comportamento de seus alunos. Além de condução de outras pesquisas que investiguem as condições de trabalho e eventos ambientais que determinam ou limitam a capacidade dos professores de intervirem no comportamento de seus alunos.Palavras-chave: avaliação funcional; interação professor-aluno; comportamento adequado; comportamento inadequado

Recomendações para oxigenoterapia domiciliar prolongada da Sociedade Brasileira de Pneumologia e Tisiologia (2022)

Some chronic respiratory diseases can cause hypoxemia and, in such cases, long-term home oxygen therapy (LTOT) is indicated as a treatment option primarily to improve patient quality of life and life expectancy. Home oxygen has been used for more than 70 years, and support for LTOT is based on two studies from the 1980s that demonstrated that oxygen use improves survival in patients with COPD. There is evidence that LTOT has other beneficial effects such as improved cognitive function, improved exercise capacity, and reduced hospitalizations. LTOT is indicated in other respiratory diseases that cause hypoxemia, on the basis of the same criteria as those used for COPD. There has been an increase in the use of LTOT, probably because of increased life expectancy and a higher prevalence of chronic respiratory diseases, as well as greater availability of LTOT in the health care system. The first Brazilian Thoracic Association consensus statement on LTOT was published in 2000. Twenty-two years later, we present this updated version. This document is a nonsystematic review of the literature, conducted by pulmonologists who evaluated scientific evidence and international guidelines on LTOT in the various diseases that cause hypoxemia and in specific situations (i.e., exercise, sleep, and air travel). These recommendations, produced with a view to clinical practice, contain several charts with information on indications for LTOT, oxygen sources, accessories, strategies for improved efficiency and effectiveness, and recommendations for the safe use of LTOT, as well as a LTOT prescribing model.Algumas doenças respiratórias crônicas podem evoluir com hipoxemia e, nessas situações, a oxigenoterapia domiciliar prolongada (ODP) está indicada como opção terapêutica com o objetivo principal de melhorar a qualidade e a expectativa de vida desses pacientes. O oxigênio domiciliar é usado há mais de 70 anos, e a ODP tem como base dois estudos da década de oitenta que demonstraram que o uso de oxigênio melhora a sobrevida de pacientes com DPOC. Existem evidências de que a ODP tem outros efeitos benéficos como melhora da função cognitiva e da capacidade de exercício e redução de hospitalizações. A ODP está indicada para outras doenças respiratórias que cursam com hipoxemia, segundo os mesmos critérios estabelecidos para a DPOC. Tem sido observado aumento no uso da ODP provavelmente pela maior expectativa de vida, maior prevalência de doenças respiratórias crônicas e maior disponibilidade de ODP no sistema de saúde. O primeiro consenso sobre ODP da Sociedade Brasileira de Pneumologia e Tisiologia foi publicado em 2000; após 22 anos, apresentamos esta versão atualizada. Este documento é uma revisão não sistemática da literatura, realizada por pneumologistas que avaliaram evidências científicas e diretrizes internacionais sobre ODP nas diversas doenças que cursam com hipoxemia e em situações específicas (exercício, sono e viagens aéreas). Estas recomendações, tendo em vista a prática clínica, oferecem diversos quadros com informações sobre indicações, fontes de oxigênio, acessórios e estratégias para melhor eficiência, efetividade e uso seguro da ODP, assim como um modelo para sua prescrição

Isolation and Characterization of Plant Growth-Promotion Diazotrophic Endophytic Bacteria Associated to Sugarcane (Saccharum officinarum L.) Grown in Paraíba, Brazil

Sugarcane is an important Brazilian commodity, being usually cultivated in soils with low natural fertility. This study aimed to isolate diazotrophic endophytes from sugarcane tissues and evaluate the morphological and physiological characteristics of their colonies as well as their plant growth-promoting (PGP) traits in select diazotrophic endophytic bacteria. Fifty-six bacterial isolates were identified in the sugarcane tissues, and these isolates presented distinct morphological and physiological traits. A total of thirty-five bacterial isolates were biochemically evaluated. Overall, Bacillus was the dominant genus. Isolates of Methylobacterium spp. and Brevibacillus agri were present only in leaves, while Herbaspirillum seropedicae occurred only in stems. Except to IPA-CF45A, all isolates were nitrogenase positive. All endophytes exhibit production of indol 3-acetic acid. Over 50% of endophytes solubilize phosphate, release N-acyl homoserine lactones, and present the activity of 1-aminocyclopropane-1-carboxylic acid deaminase, catalase, lipase and protease. The network analysis showed that isolates belonged to Burkholderia, Herbaspirillum, and Methylobacterium interact with Bacillus. Bacterial endophytes exhibited distinct morphological, physiological, and PGP traits that are useful for sustainable agriculture, highlighting the isolates IPA-CC33, IPA-CF65, IPA-CC9 and IPA-CF27. Further studies on the effects of these diazotrophic endophytes and their potential for providing microbial inoculants for improving sugarcane fields will provide valuable information to maintain the sustainability and environment quality.National Council for Scientific and Technological Development 426655/2018-