6,692 research outputs found

    Medique con cuidado

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    The Cultural Construction of the Maine Sporting Camps

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    Maine’s lakes and forests attracted a growing number of urban hunters and anglers after 1880. Attracted in part by the informality and remoteness of the Maine woods, these urban recreationists nevertheless imposed their own sense of order and propriety upon the culture of the sporting camp. Urban “sports “ went “back to nature, ” yet maintained their status - and their social distance - as ladies and gentlemen.

    Mutual information between geomagnetic indices and the solar wind as seen by WIND : implications for propagation time estimates

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    The determination of delay times of solar wind conditions at the sunward libration point to effects on Earth is investigated using mutual information. This measures the amount of information shared between two timeseries. We consider the mutual information content of solar wind observations, from WIND, and the geomagnetic indices. The success of five commonly used schemes for estimating interplanetary propagation times is examined. Propagation assuming a fixed plane normal at 45 degrees to the GSE x-axis (i.e. the Parker Spiral estimate) is found to give optimal mutual information. The mutual information depends on the point in space chosen as the target for the propagation estimate, and we find that it is maximized by choosing a point in the nightside rather than dayside magnetosphere. In addition, we employ recurrence plot analysis to visualize contributions to the mutual information, this suggests that it appears on timescales of hours rather than minutes

    Information entropy and nucleon correlations in nuclei

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    The information entropies in coordinate and momentum spaces and their sum (SrS_r, SkS_k, SS) are evaluated for many nuclei using "experimental" densities or/and momentum distributions. The results are compared with the harmonic oscillator model and with the short-range correlated distributions. It is found that SrS_r depends strongly on lnA\ln A and does not depend very much on the model. The behaviour of SkS_k is opposite. The various cases we consider can be classified according to either the quantity of the experimental data we use or by the values of SS, i.e., the increase of the quality of the density and of the momentum distributions leads to an increase of the values of SS. In all cases, apart from the linear relation S=a+blnAS=a+b\ln A, the linear relation S=aV+bVlnVS=a_V+b_V \ln V also holds. V is the mean volume of the nucleus. If SS is considered as an ensemble entropy, a relation between AA or VV and the ensemble volume can be found. Finally, comparing different electron scattering experiments for the same nucleus, it is found that the larger the momentum transfer ranges, the larger the information entropy is. It is concluded that SS could be used to compare different experiments for the same nucleus and to choose the most reliable one.Comment: 14 pages, 4 figures, 2 table

    Recruitment of Activation Receptors at Inhibitory NK Cell Immune Synapses

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    Natural killer (NK) cell activation receptors accumulate by an actin-dependent process at cytotoxic immune synapses where they provide synergistic signals that trigger NK cell effector functions. In contrast, NK cell inhibitory receptors, including members of the MHC class I-specific killer cell Ig-like receptor (KIR) family, accumulate at inhibitory immune synapses, block actin dynamics, and prevent actin-dependent phosphorylation of activation receptors. Therefore, one would predict inhibition of actin-dependent accumulation of activation receptors when inhibitory receptors are engaged. By confocal imaging of primary human NK cells in contact with target cells expressing physiological ligands of NK cell receptors, we show here that this prediction is incorrect. Target cells included a human cell line and transfected Drosophila insect cells that expressed ligands of NK cell activation receptors in combination with an MHC class I ligand of inhibitory KIR. The two NK cell activation receptors CD2 and 2B4 accumulated and co-localized with KIR at inhibitory immune synapses. In fact, KIR promoted CD2 and 2B4 clustering, as CD2 and 2B4 accumulated more efficiently at inhibitory synapses. In contrast, accumulation of KIR and of activation receptors at inhibitory synapses correlated with reduced density of the integrin LFA-1. These results imply that inhibitory KIR does not prevent CD2 and 2B4 signaling by blocking their accumulation at NK cell immune synapses, but by blocking their ability to signal within inhibitory synapses

    An automatic system for crystal growth studies at constant supersaturation

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    An automatic system for growing crystals from seeded supersaturated solutions at constant supersaturation is described. Control of burettes and data acquisition are controlled by computer. The system was tested with a study of the calcium oxalate kinetics of crystal growth

    Implementation Strategies for Interventions Aiming to Increase Participation in Mail-Out Bowel Cancer Screening Programs: A Realist Review.

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    Background: Bowel cancer is the third most commonly diagnosed cancer and the third most common cause of cancer-related death, with 1,849,518 new cases of bowel diagnosed and 880,792 deaths reported globally in 2018 alone. Survival can be improved through early detection via national mail-out bowel cancer screening programs; however, participation remains low in many countries. Behavior change is therefore required to increase participation. This realist review aims to (a) identify the behavior change techniques (BCTs) used in each intervention, (b) understand the mechanisms of action (MoAs) responsible for the BCT effectiveness, and (c) apply a behavior change model to inform how MoAs can be combined to increase screening participation. Methods: We systematically reviewed the literature for interventions aiming to increase participation in mail-out bowel cancer screening. We used a four-stage realist synthesis approach whereby (1) interventions were extracted from each study; (2) BCTs applied in each intervention were identified and coded using the BCT Taxonomy-v1; (3) the Theory and Techniques Tool was used to link BCTs to their MoA; and (4) BCTs and MoAs were categorized according to their effectiveness and what Health Action Process Approach (HAPA) stage of change they would affect. Results: We identified 68 intervention trials using 26 unique BCTs and 13 MoAs to increase participation. Sixteen BCTs and 10 MoAs were identified within the interventions that successfully increased participation rates. Interventions targeting both stages of the HAPA model had a higher success rate (80%) than those targeting one stage of change (51%). When targeting only one stage, interventions targeting the volitional stage had a higher success rate (71%) than interventions targeting only the motivational stage of change (26%). Conclusion: Importantly, this review identified a suite of BCTs and MoAs effective for increasing participation in mail-out bowel cancer screening programs. With increased participation in bowel cancer screening leading to improved survival, our findings are key to informing the improvement of policy and interventions that aim to increase screening using specific strategies at key stages of health decision-making

    Liquid heat capacity in the approach from the solid state: anharmonic theory

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    Calculating liquid energy and heat capacity in general form is an open problem in condensed matter physics. We develop a recent approach to liquids from the solid state by accounting for the contribution of anharmonicity and thermal expansion to liquid energy and heat capacity. We subsequently compare theoretical predictions to the experiments results of 5 commonly discussed liquids, and find a good agreement with no free fitting parameters. We discuss and compare the proposed theory to previous approaches.Comment: 8 pages, 6 figure
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